JP2010535015A5 - - Google Patents
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- Publication number
- JP2010535015A5 JP2010535015A5 JP2010517242A JP2010517242A JP2010535015A5 JP 2010535015 A5 JP2010535015 A5 JP 2010535015A5 JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010535015 A5 JP2010535015 A5 JP 2010535015A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- seq
- monoclonal antibody
- produced
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 34
- 108090000765 processed proteins & peptides Proteins 0.000 claims 22
- 210000004408 hybridoma Anatomy 0.000 claims 19
- 229920001184 polypeptide Polymers 0.000 claims 19
- 102000004196 processed proteins & peptides Human genes 0.000 claims 19
- 241000699666 Mus <mouse, genus> Species 0.000 claims 18
- 102000039446 nucleic acids Human genes 0.000 claims 17
- 108020004707 nucleic acids Proteins 0.000 claims 17
- 150000007523 nucleic acids Chemical class 0.000 claims 17
- 239000000523 sample Substances 0.000 claims 11
- 239000012472 biological sample Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 241000194017 Streptococcus Species 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 5
- 208000035109 Pneumococcal Infections Diseases 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 4
- 230000002163 immunogen Effects 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 238000003259 recombinant expression Methods 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 201000009906 Meningitis Diseases 0.000 claims 1
- 241000699670 Mus sp. Species 0.000 claims 1
- 206010033078 Otitis media Diseases 0.000 claims 1
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 206010061372 Streptococcal infection Diseases 0.000 claims 1
- 108700029229 Transcriptional Regulatory Elements Proteins 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002949 hemolytic effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000007922 nasal spray Substances 0.000 claims 1
- 229940097496 nasal spray Drugs 0.000 claims 1
- 239000006199 nebulizer Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96172307P | 2007-07-23 | 2007-07-23 | |
| PCT/CA2008/001353 WO2009012588A1 (en) | 2007-07-23 | 2008-07-23 | Immunogenic polypeptides and monoclonal antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013089148A Division JP6204053B2 (ja) | 2007-07-23 | 2013-04-22 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010535015A JP2010535015A (ja) | 2010-11-18 |
| JP2010535015A5 true JP2010535015A5 (enExample) | 2011-08-11 |
Family
ID=40280955
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517242A Pending JP2010535015A (ja) | 2007-07-23 | 2008-07-23 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
| JP2013089148A Expired - Fee Related JP6204053B2 (ja) | 2007-07-23 | 2013-04-22 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
| JP2015196681A Pending JP2016005482A (ja) | 2007-07-23 | 2015-10-02 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013089148A Expired - Fee Related JP6204053B2 (ja) | 2007-07-23 | 2013-04-22 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
| JP2015196681A Pending JP2016005482A (ja) | 2007-07-23 | 2015-10-02 | 免疫原性のポリペプチドおよびモノクローナル抗体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8337846B2 (enExample) |
| EP (1) | EP2183366B1 (enExample) |
| JP (3) | JP2010535015A (enExample) |
| KR (1) | KR101595234B1 (enExample) |
| CN (1) | CN101802198B (enExample) |
| AU (1) | AU2008280799B2 (enExample) |
| BR (1) | BRPI0814127A2 (enExample) |
| CA (1) | CA2694466A1 (enExample) |
| ES (1) | ES2397488T3 (enExample) |
| IL (1) | IL203429A0 (enExample) |
| WO (1) | WO2009012588A1 (enExample) |
| ZA (1) | ZA201001260B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| US20130183350A1 (en) | 2009-12-22 | 2013-07-18 | Kevin Harper | Immunogenic compositions |
| CA2784447A1 (en) | 2009-12-22 | 2011-06-30 | Sanofi Pasteur Limited | Adjuvanted immunogenic compositions and related methods |
| GB201003920D0 (en) * | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
| CA2819758A1 (en) | 2010-12-03 | 2012-06-07 | Sanofi Pasteur Limited | Composition for immunization against streptococcus pneumoniae |
| BR112013029514A2 (pt) | 2011-05-17 | 2019-09-24 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, e, método de tratar ou impedir uma doença |
| JP2015508755A (ja) * | 2012-02-01 | 2015-03-23 | オクラホマ メディカル リサーチ ファウンデーションＯｋｌａｈｏｍａ Ｍｅｄｉｃａｌ Ｒｅｓｅａｒｃｈｆｏｕｎｄａｔｉｏｎ | ヒト肺炎連鎖球菌抗体およびその使用 |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| CN105754952B (zh) * | 2016-02-16 | 2020-07-10 | 中国农业科学院兰州兽医研究所 | 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用 |
| GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| WO2019180618A1 (en) * | 2018-03-20 | 2019-09-26 | Sanofi Pasteur Limited | Methods for determining adjuvanted protein concentration and percent adsorption using intrinsic fluorescence |
| EP4291306A1 (en) * | 2021-02-09 | 2023-12-20 | University of Georgia Research Foundation, Inc. | Human monoclonal antibodies against pneumococcal antigens |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL81370A (en) * | 1986-02-07 | 1991-06-30 | Genetic Systems Corp | Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions |
| JP4087896B2 (ja) * | 1991-11-22 | 2008-05-21 | ナビ・バイオフアーマシユテイカルズ | スタフィロコッカス・エピダーミジス関連ｉ及びｉｉ型表面抗原 |
| US6582708B1 (en) * | 2000-06-28 | 2003-06-24 | The Procter & Gamble Company | Tooth whitening substance |
| DK1140157T3 (da) | 1998-12-21 | 2009-06-08 | Medimmune Inc | Streptococcus pneumoniae-proteiner og immunogene fragmenter til vacciner |
| ATE394489T1 (de) * | 1998-12-23 | 2008-05-15 | Id Biomedical Corp | Streptococcus antigene |
| US7128918B1 (en) * | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| WO2000058475A2 (en) * | 1999-03-26 | 2000-10-05 | Provalis Uk Limited | Streptococcus pneumoniae antigens |
| JP2004503565A (ja) * | 2000-06-14 | 2004-02-05 | サイトヴァックス・バイオテクノロジーズ・インコーポレーテッド | 構造特異的ペプチドを生産するためのコイルドコイル構造的骨格の使用 |
| EA006232B1 (ru) * | 2000-06-20 | 2005-10-27 | Ай Ди Биомедикал Корпорейшн | Стрептококковые антигены |
| US7074415B2 (en) * | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
| GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| GB0130215D0 (en) * | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
| AU2002351623A1 (en) * | 2001-12-20 | 2003-07-09 | Shire Biochem Inc. | Streptococcus antigens |
| US6720918B2 (en) * | 2002-09-17 | 2004-04-13 | Space Systems/Loral, Inc. | Antenna distortion estimation and compensation |
| EP2336357A1 (en) * | 2003-04-15 | 2011-06-22 | Intercell AG | S. pneumoniae antigens |
| BRPI0412418A (pt) * | 2003-07-10 | 2006-08-22 | Wyeth Corp | expressão recombinante de protease de cisteìna de streptococcus pyogenes e composições imunogênicas da mesma |
| EP1919934A2 (en) * | 2005-05-13 | 2008-05-14 | Novartis Vaccines and Diagnostics, Inc. | Serum resistance factors of gram positive bacteria |
| JP5509176B2 (ja) * | 2011-10-21 | 2014-06-04 | 株式会社日立製作所 | 計算機システムおよび計算機システムにおけるモジュール引き継ぎ方法 |
-
2008
- 2008-07-23 AU AU2008280799A patent/AU2008280799B2/en not_active Ceased
- 2008-07-23 JP JP2010517242A patent/JP2010535015A/ja active Pending
- 2008-07-23 WO PCT/CA2008/001353 patent/WO2009012588A1/en not_active Ceased
- 2008-07-23 CA CA2694466A patent/CA2694466A1/en not_active Abandoned
- 2008-07-23 EP EP08783266A patent/EP2183366B1/en not_active Not-in-force
- 2008-07-23 ES ES08783266T patent/ES2397488T3/es active Active
- 2008-07-23 KR KR1020107003640A patent/KR101595234B1/ko not_active Expired - Fee Related
- 2008-07-23 BR BRPI0814127-4A2A patent/BRPI0814127A2/pt not_active Application Discontinuation
- 2008-07-23 CN CN200880108203.5A patent/CN101802198B/zh not_active Expired - Fee Related
- 2008-07-23 US US12/670,150 patent/US8337846B2/en not_active Expired - Fee Related
-
2010
- 2010-01-21 IL IL203429A patent/IL203429A0/en unknown
- 2010-02-22 ZA ZA201001260A patent/ZA201001260B/xx unknown
-
2013
- 2013-04-22 JP JP2013089148A patent/JP6204053B2/ja not_active Expired - Fee Related
-
2015
- 2015-10-02 JP JP2015196681A patent/JP2016005482A/ja active Pending
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