AU2008280799B2 - Immunogenic polypeptides and monoclonal antibodies - Google Patents

Immunogenic polypeptides and monoclonal antibodies Download PDF

Info

Publication number
AU2008280799B2
AU2008280799B2 AU2008280799A AU2008280799A AU2008280799B2 AU 2008280799 B2 AU2008280799 B2 AU 2008280799B2 AU 2008280799 A AU2008280799 A AU 2008280799A AU 2008280799 A AU2008280799 A AU 2008280799A AU 2008280799 B2 AU2008280799 B2 AU 2008280799B2
Authority
AU
Australia
Prior art keywords
seq
polypeptide
composition
phtd
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008280799A
Other languages
English (en)
Other versions
AU2008280799A1 (en
Inventor
Roger Brookes
Robert Charlebois
Martina Ochs
Jeremy Yethon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Sanofi Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Ltd filed Critical Sanofi Pasteur Ltd
Publication of AU2008280799A1 publication Critical patent/AU2008280799A1/en
Application granted granted Critical
Publication of AU2008280799B2 publication Critical patent/AU2008280799B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
AU2008280799A 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies Ceased AU2008280799B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96172307P 2007-07-23 2007-07-23
US60/961,723 2007-07-23
PCT/CA2008/001353 WO2009012588A1 (en) 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies

Publications (2)

Publication Number Publication Date
AU2008280799A1 AU2008280799A1 (en) 2009-01-29
AU2008280799B2 true AU2008280799B2 (en) 2013-07-11

Family

ID=40280955

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008280799A Ceased AU2008280799B2 (en) 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies

Country Status (12)

Country Link
US (1) US8337846B2 (enExample)
EP (1) EP2183366B1 (enExample)
JP (3) JP2010535015A (enExample)
KR (1) KR101595234B1 (enExample)
CN (1) CN101802198B (enExample)
AU (1) AU2008280799B2 (enExample)
BR (1) BRPI0814127A2 (enExample)
CA (1) CA2694466A1 (enExample)
ES (1) ES2397488T3 (enExample)
IL (1) IL203429A0 (enExample)
WO (1) WO2009012588A1 (enExample)
ZA (1) ZA201001260B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
WO2011075822A1 (en) 2009-12-22 2011-06-30 Sanofi Pasteur Limited Immunogenic compositions and related methods
KR20120107121A (ko) 2009-12-22 2012-09-28 사노피 파스퇴르 리미티드 면역원성 조성물
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
AU2011336366B2 (en) 2010-12-03 2016-05-12 Sanofi Pasteur Limited Composition for immunization against Streptococcus pneumoniae
KR20140033127A (ko) 2011-05-17 2014-03-17 글락소스미스클라인 바이오로지칼즈 에스.에이. 스트렙토코쿠스 뉴모니애에 대한 백신
EP2810078A4 (en) * 2012-02-01 2016-02-17 Oklahoma Med Res Found HUMAN STREPTOCOCCUS PNEUMONIAE ANTIBODIES AND APPLICATIONS THEREOF
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CN105754952B (zh) * 2016-02-16 2020-07-10 中国农业科学院兰州兽医研究所 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
GB201711635D0 (en) 2017-07-19 2017-08-30 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2019180618A1 (en) * 2018-03-20 2019-09-26 Sanofi Pasteur Limited Methods for determining adjuvanted protein concentration and percent adsorption using intrinsic fluorescence
CN117396502A (zh) * 2021-02-09 2024-01-12 佐治亚大学研究基金会有限公司 针对肺炎球菌抗原的人类单克隆抗体

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001098334A2 (en) * 2000-06-20 2001-12-27 Shire Biochem Inc. Streptococcus antigens
WO2003054007A2 (en) * 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81370A (en) * 1986-02-07 1991-06-30 Genetic Systems Corp Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions
ES2198405T3 (es) * 1991-11-22 2004-02-01 Nabi Biopharmaceuticals Antigenos de superficie de tipo i asociados a staphylococcus epidermis.
US6582708B1 (en) * 2000-06-28 2003-06-24 The Procter & Gamble Company Tooth whitening substance
CA2355364C (en) 1998-12-21 2014-03-18 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
PL205041B1 (pl) * 1998-12-23 2010-03-31 Id Biomedical Corp Izolowany polinukleotyd, wektor zawierający izolowany polinukleotyd, komórka gospodarza transfekowana lub transformowana za pomocą tego wektora, sposób wytwarzania polipeptydu kodowanego przez izolowany polinukleotyd, izolowany polipeptyd, chimeryczny polipeptyd, kompozycja do szczepionek zawierająca polipeptyd oraz jej zastosowanie w leczeniu lub zapobieganiu zakażeniu osobnika paciorkowcem
CN1198932C (zh) * 1999-03-26 2005-04-27 科特克斯(Om)有限公司 肺炎链球菌抗原
EP1290019A2 (en) * 2000-06-14 2003-03-12 Cytovax Biotechnologies Inc. Use of coiled-coil structural scaffold to generate structure-specific peptides
US7074415B2 (en) * 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
GB0130215D0 (en) 2001-12-18 2002-02-06 Glaxosmithkline Biolog Sa Vaccine
US6720918B2 (en) * 2002-09-17 2004-04-13 Space Systems/Loral, Inc. Antenna distortion estimation and compensation
US7635487B2 (en) * 2003-04-15 2009-12-22 Intercell Ag S. pneumoniae antigens
AU2004257206A1 (en) * 2003-07-10 2005-01-27 Wyeth Holdings Corporation Recombinant expression of Streptococcus pyogenes cysteine protease and immunogenic compositions thereof
EP1919934A2 (en) * 2005-05-13 2008-05-14 Novartis Vaccines and Diagnostics, Inc. Serum resistance factors of gram positive bacteria
JP5509176B2 (ja) * 2011-10-21 2014-06-04 株式会社日立製作所 計算機システムおよび計算機システムにおけるモジュール引き継ぎ方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001098334A2 (en) * 2000-06-20 2001-12-27 Shire Biochem Inc. Streptococcus antigens
WO2003054007A2 (en) * 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens

Also Published As

Publication number Publication date
BRPI0814127A2 (pt) 2015-02-03
IL203429A0 (en) 2011-07-31
CN101802198A (zh) 2010-08-11
JP6204053B2 (ja) 2017-09-27
AU2008280799A1 (en) 2009-01-29
US8337846B2 (en) 2012-12-25
CN101802198B (zh) 2016-02-17
EP2183366B1 (en) 2012-10-24
CA2694466A1 (en) 2009-01-29
JP2010535015A (ja) 2010-11-18
JP2013212108A (ja) 2013-10-17
WO2009012588A1 (en) 2009-01-29
KR20100053564A (ko) 2010-05-20
JP2016005482A (ja) 2016-01-14
KR101595234B1 (ko) 2016-02-26
US20100297133A1 (en) 2010-11-25
ZA201001260B (en) 2010-10-27
EP2183366A4 (en) 2010-09-01
EP2183366A1 (en) 2010-05-12
ES2397488T3 (es) 2013-03-07

Similar Documents

Publication Publication Date Title
US8337846B2 (en) Immunogenic polypeptides and monoclonal antibodies
AU2009329782B2 (en) Modified Streptococcus pneumonia pneumolysin (PLY) polypeptides
JP4469026B2 (ja) Ｓｔｒｅｐｔｏｃｏｃｃｕｓ ｐｎｅｕｍｏｎｉａｅの抗原およびワクチン
CA2347849C (en) Omp85 proteins of neisseria gonorrhoeae and neisseria meningitidis, compositions containing same and methods of use thereof
KR20070122458A (ko) 표재성 스트렙토코커스 뉴모니아 폴리펩티드
PL197449B1 (pl) Wyizolowane polipeptydy, immunogenne fragmenty tych polipeptydów, wyizolowane polinukleotydy, wektor ekspresyjny, komórka gospodarza zawierająca taki wektor, sposób wytwarzania polipeptydu, sposób ekspresji polinukleotydu, kompozycja szczepionki, przeciwciało immunospecyficzne w stosunku do polipeptydu lub jego immunogennego fragmentu, sposób diagnozowania zakażenia Neisseria meningitidis, zastosowania kompozycji zawierającej polipeptyd lub jego immunogenny fragment, lub polinukleotyd i kompozycja terapeutyczna do leczenia choroby wywołanej przez Neisseria meningitidis
AU2013204613A1 (en) Modified Streptococcus pneumonia pneumolysin (PLY) polypeptides
US20040131634A1 (en) Neisseria lactoferrin binding protein
US20130184200A1 (en) Immunogenic Polypeptides and Monoclonal Antibodies
Class et al. Patent application title: Immunogenic Polypeptides and Monoclonal Antibodies Inventors: Martina Ochs (Toronto, CA) Roger Brooks (Toronto, CA) Robert Charlebois (Toronto, CA) Jeremy Yethon (Milton, CA)
AU2016254447A1 (en) Modified Streptococcus pneumonia pneumolysin (PLY) polypeptides
EP1535928A2 (en) Omp85 proteins of Neisseria gonorrhoeae and Neisseria meningitidis, compositions containing same and methods of use thereof
US20080039386A1 (en) Methods and Compositions for Diagnosing and Preventing a Group B Streptococcal Infection
EP1939215A1 (en) Omp85 proteins of neisseria gonorrhoeae and neisseria meningitidis, compositions containing same and methods of use thereof
HK1243089A1 (en) Immunogenic pcpa polypeptides and uses thereof
CZ20004395A3 (cs) Antigenní polypeptidy Neisseria meningitidis, příslušné polynukleotidy a protektivní protilátky
CA2634911A1 (en) Neisseria meningitidis vaccines and their use

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired