AU2008280799B2 - Immunogenic polypeptides and monoclonal antibodies - Google Patents

Immunogenic polypeptides and monoclonal antibodies Download PDF

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Publication number
AU2008280799B2
AU2008280799B2 AU2008280799A AU2008280799A AU2008280799B2 AU 2008280799 B2 AU2008280799 B2 AU 2008280799B2 AU 2008280799 A AU2008280799 A AU 2008280799A AU 2008280799 A AU2008280799 A AU 2008280799A AU 2008280799 B2 AU2008280799 B2 AU 2008280799B2
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AU
Australia
Prior art keywords
seq
polypeptide
composition
phtd
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008280799A
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English (en)
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AU2008280799A1 (en
Inventor
Roger Brookes
Robert Charlebois
Martina Ochs
Jeremy Yethon
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Sanofi Pasteur Ltd
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Sanofi Pasteur Ltd
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Publication of AU2008280799A1 publication Critical patent/AU2008280799A1/en
Application granted granted Critical
Publication of AU2008280799B2 publication Critical patent/AU2008280799B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
AU2008280799A 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies Ceased AU2008280799B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96172307P 2007-07-23 2007-07-23
US60/961,723 2007-07-23
PCT/CA2008/001353 WO2009012588A1 (en) 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies

Publications (2)

Publication Number Publication Date
AU2008280799A1 AU2008280799A1 (en) 2009-01-29
AU2008280799B2 true AU2008280799B2 (en) 2013-07-11

Family

ID=40280955

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008280799A Ceased AU2008280799B2 (en) 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies

Country Status (12)

Country Link
US (1) US8337846B2 (enExample)
EP (1) EP2183366B1 (enExample)
JP (3) JP2010535015A (enExample)
KR (1) KR101595234B1 (enExample)
CN (1) CN101802198B (enExample)
AU (1) AU2008280799B2 (enExample)
BR (1) BRPI0814127A2 (enExample)
CA (1) CA2694466A1 (enExample)
ES (1) ES2397488T3 (enExample)
IL (1) IL203429A0 (enExample)
WO (1) WO2009012588A1 (enExample)
ZA (1) ZA201001260B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
US20130183350A1 (en) 2009-12-22 2013-07-18 Kevin Harper Immunogenic compositions
CA2784447A1 (en) 2009-12-22 2011-06-30 Sanofi Pasteur Limited Adjuvanted immunogenic compositions and related methods
GB201003920D0 (en) * 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
CA2819758A1 (en) 2010-12-03 2012-06-07 Sanofi Pasteur Limited Composition for immunization against streptococcus pneumoniae
BR112013029514A2 (pt) 2011-05-17 2019-09-24 Glaxosmithkline Biologicals Sa composição imunogênica, vacina, e, método de tratar ou impedir uma doença
JP2015508755A (ja) * 2012-02-01 2015-03-23 オクラホマ メディカル リサーチ ファウンデーションOklahoma Medical Researchfoundation ヒト肺炎連鎖球菌抗体およびその使用
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CN105754952B (zh) * 2016-02-16 2020-07-10 中国农业科学院兰州兽医研究所 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
WO2019180618A1 (en) * 2018-03-20 2019-09-26 Sanofi Pasteur Limited Methods for determining adjuvanted protein concentration and percent adsorption using intrinsic fluorescence
EP4291306A1 (en) * 2021-02-09 2023-12-20 University of Georgia Research Foundation, Inc. Human monoclonal antibodies against pneumococcal antigens

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001098334A2 (en) * 2000-06-20 2001-12-27 Shire Biochem Inc. Streptococcus antigens
WO2003054007A2 (en) * 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81370A (en) * 1986-02-07 1991-06-30 Genetic Systems Corp Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions
JP4087896B2 (ja) * 1991-11-22 2008-05-21 ナビ・バイオフアーマシユテイカルズ スタフィロコッカス・エピダーミジス関連i及びii型表面抗原
US6582708B1 (en) * 2000-06-28 2003-06-24 The Procter & Gamble Company Tooth whitening substance
DK1140157T3 (da) 1998-12-21 2009-06-08 Medimmune Inc Streptococcus pneumoniae-proteiner og immunogene fragmenter til vacciner
ATE394489T1 (de) * 1998-12-23 2008-05-15 Id Biomedical Corp Streptococcus antigene
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
WO2000058475A2 (en) * 1999-03-26 2000-10-05 Provalis Uk Limited Streptococcus pneumoniae antigens
JP2004503565A (ja) * 2000-06-14 2004-02-05 サイトヴァックス・バイオテクノロジーズ・インコーポレーテッド 構造特異的ペプチドを生産するためのコイルドコイル構造的骨格の使用
US7074415B2 (en) * 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
GB0130215D0 (en) * 2001-12-18 2002-02-06 Glaxosmithkline Biolog Sa Vaccine
US6720918B2 (en) * 2002-09-17 2004-04-13 Space Systems/Loral, Inc. Antenna distortion estimation and compensation
EP2336357A1 (en) * 2003-04-15 2011-06-22 Intercell AG S. pneumoniae antigens
BRPI0412418A (pt) * 2003-07-10 2006-08-22 Wyeth Corp expressão recombinante de protease de cisteìna de streptococcus pyogenes e composições imunogênicas da mesma
EP1919934A2 (en) * 2005-05-13 2008-05-14 Novartis Vaccines and Diagnostics, Inc. Serum resistance factors of gram positive bacteria
JP5509176B2 (ja) * 2011-10-21 2014-06-04 株式会社日立製作所 計算機システムおよび計算機システムにおけるモジュール引き継ぎ方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001098334A2 (en) * 2000-06-20 2001-12-27 Shire Biochem Inc. Streptococcus antigens
WO2003054007A2 (en) * 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens

Also Published As

Publication number Publication date
US20100297133A1 (en) 2010-11-25
ZA201001260B (en) 2010-10-27
JP2010535015A (ja) 2010-11-18
US8337846B2 (en) 2012-12-25
CN101802198B (zh) 2016-02-17
CA2694466A1 (en) 2009-01-29
WO2009012588A1 (en) 2009-01-29
EP2183366B1 (en) 2012-10-24
BRPI0814127A2 (pt) 2015-02-03
AU2008280799A1 (en) 2009-01-29
JP2016005482A (ja) 2016-01-14
JP6204053B2 (ja) 2017-09-27
EP2183366A4 (en) 2010-09-01
IL203429A0 (en) 2011-07-31
CN101802198A (zh) 2010-08-11
ES2397488T3 (es) 2013-03-07
KR101595234B1 (ko) 2016-02-26
KR20100053564A (ko) 2010-05-20
EP2183366A1 (en) 2010-05-12
JP2013212108A (ja) 2013-10-17

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