JP2010535015A - 免疫原性のポリペプチドおよびモノクローナル抗体 - Google Patents

免疫原性のポリペプチドおよびモノクローナル抗体 Download PDF

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Publication number
JP2010535015A
JP2010535015A JP2010517242A JP2010517242A JP2010535015A JP 2010535015 A JP2010535015 A JP 2010535015A JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010517242 A JP2010517242 A JP 2010517242A JP 2010535015 A JP2010535015 A JP 2010535015A
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JP
Japan
Prior art keywords
seq
produced
hybridoma
nucleic acid
mouse
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JP2010517242A
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English (en)
Japanese (ja)
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JP2010535015A5 (enExample
Inventor
オクス，マルティナ
ブルックス，ロジャー
チャールボイス，ロバート
イェソン，ジェレミー
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Sanofi Pasteur Ltd
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Sanofi Pasteur Ltd
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Publication of JP2010535015A publication Critical patent/JP2010535015A/ja
Publication of JP2010535015A5 publication Critical patent/JP2010535015A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
JP2010517242A 2007-07-23 2008-07-23 免疫原性のポリペプチドおよびモノクローナル抗体 Pending JP2010535015A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96172307P 2007-07-23 2007-07-23
PCT/CA2008/001353 WO2009012588A1 (en) 2007-07-23 2008-07-23 Immunogenic polypeptides and monoclonal antibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013089148A Division JP6204053B2 (ja) 2007-07-23 2013-04-22 免疫原性のポリペプチドおよびモノクローナル抗体

Publications (2)

Publication Number Publication Date
JP2010535015A true JP2010535015A (ja) 2010-11-18
JP2010535015A5 JP2010535015A5 (enExample) 2011-08-11

Family

ID=40280955

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010517242A Pending JP2010535015A (ja) 2007-07-23 2008-07-23 免疫原性のポリペプチドおよびモノクローナル抗体
JP2013089148A Expired - Fee Related JP6204053B2 (ja) 2007-07-23 2013-04-22 免疫原性のポリペプチドおよびモノクローナル抗体
JP2015196681A Pending JP2016005482A (ja) 2007-07-23 2015-10-02 免疫原性のポリペプチドおよびモノクローナル抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2013089148A Expired - Fee Related JP6204053B2 (ja) 2007-07-23 2013-04-22 免疫原性のポリペプチドおよびモノクローナル抗体
JP2015196681A Pending JP2016005482A (ja) 2007-07-23 2015-10-02 免疫原性のポリペプチドおよびモノクローナル抗体

Country Status (12)

Country Link
US (1) US8337846B2 (enExample)
EP (1) EP2183366B1 (enExample)
JP (3) JP2010535015A (enExample)
KR (1) KR101595234B1 (enExample)
CN (1) CN101802198B (enExample)
AU (1) AU2008280799B2 (enExample)
BR (1) BRPI0814127A2 (enExample)
CA (1) CA2694466A1 (enExample)
ES (1) ES2397488T3 (enExample)
IL (1) IL203429A0 (enExample)
WO (1) WO2009012588A1 (enExample)
ZA (1) ZA201001260B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021518559A (ja) * 2018-03-20 2021-08-02 サノフィ パスツ−ル リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ 固有蛍光を使用して、アジュバント化タンパク質濃度及びパーセント吸着を決定する方法

Families Citing this family (12)

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US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
WO2011075822A1 (en) 2009-12-22 2011-06-30 Sanofi Pasteur Limited Immunogenic compositions and related methods
KR20120107121A (ko) 2009-12-22 2012-09-28 사노피 파스퇴르 리미티드 면역원성 조성물
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
AU2011336366B2 (en) 2010-12-03 2016-05-12 Sanofi Pasteur Limited Composition for immunization against Streptococcus pneumoniae
KR20140033127A (ko) 2011-05-17 2014-03-17 글락소스미스클라인 바이오로지칼즈 에스.에이. 스트렙토코쿠스 뉴모니애에 대한 백신
EP2810078A4 (en) * 2012-02-01 2016-02-17 Oklahoma Med Res Found HUMAN STREPTOCOCCUS PNEUMONIAE ANTIBODIES AND APPLICATIONS THEREOF
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CN105754952B (zh) * 2016-02-16 2020-07-10 中国农业科学院兰州兽医研究所 抗羊痘病毒k3l蛋白c末端的单克隆抗体及其应用
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
GB201711635D0 (en) 2017-07-19 2017-08-30 Glaxosmithkline Biologicals Sa Immunogenic composition
CN117396502A (zh) * 2021-02-09 2024-01-12 佐治亚大学研究基金会有限公司 针对肺炎球菌抗原的人类单克隆抗体

Citations (1)

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WO2003054007A2 (en) * 2001-12-20 2003-07-03 Shire Biochem Inc. Streptococcus antigens

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ES2198405T3 (es) * 1991-11-22 2004-02-01 Nabi Biopharmaceuticals Antigenos de superficie de tipo i asociados a staphylococcus epidermis.
US6582708B1 (en) * 2000-06-28 2003-06-24 The Procter & Gamble Company Tooth whitening substance
CA2355364C (en) 1998-12-21 2014-03-18 Medimmune, Inc. Streptococcus pneumoniae proteins and immunogenic fragments for vaccines
US7128918B1 (en) * 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
PL205041B1 (pl) * 1998-12-23 2010-03-31 Id Biomedical Corp Izolowany polinukleotyd, wektor zawierający izolowany polinukleotyd, komórka gospodarza transfekowana lub transformowana za pomocą tego wektora, sposób wytwarzania polipeptydu kodowanego przez izolowany polinukleotyd, izolowany polipeptyd, chimeryczny polipeptyd, kompozycja do szczepionek zawierająca polipeptyd oraz jej zastosowanie w leczeniu lub zapobieganiu zakażeniu osobnika paciorkowcem
CN1198932C (zh) * 1999-03-26 2005-04-27 科特克斯(Om)有限公司 肺炎链球菌抗原
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021518559A (ja) * 2018-03-20 2021-08-02 サノフィ パスツ−ル リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ 固有蛍光を使用して、アジュバント化タンパク質濃度及びパーセント吸着を決定する方法
JP7413271B2 (ja) 2018-03-20 2024-01-15 サノフィ パスツ－ル リミテッド 固有蛍光を使用して、アジュバント化タンパク質濃度及びパーセント吸着を決定する方法

Also Published As

Publication number Publication date
BRPI0814127A2 (pt) 2015-02-03
IL203429A0 (en) 2011-07-31
CN101802198A (zh) 2010-08-11
JP6204053B2 (ja) 2017-09-27
AU2008280799A1 (en) 2009-01-29
US8337846B2 (en) 2012-12-25
CN101802198B (zh) 2016-02-17
EP2183366B1 (en) 2012-10-24
AU2008280799B2 (en) 2013-07-11
CA2694466A1 (en) 2009-01-29
JP2013212108A (ja) 2013-10-17
WO2009012588A1 (en) 2009-01-29
KR20100053564A (ko) 2010-05-20
JP2016005482A (ja) 2016-01-14
KR101595234B1 (ko) 2016-02-26
US20100297133A1 (en) 2010-11-25
ZA201001260B (en) 2010-10-27
EP2183366A4 (en) 2010-09-01
EP2183366A1 (en) 2010-05-12
ES2397488T3 (es) 2013-03-07

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