JP2010532657A - クレブシエラ属の抗原 - Google Patents

クレブシエラ属の抗原 Download PDF

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JP2010532657A
JP2010532657A JP2010504730A JP2010504730A JP2010532657A JP 2010532657 A JP2010532657 A JP 2010532657A JP 2010504730 A JP2010504730 A JP 2010504730A JP 2010504730 A JP2010504730 A JP 2010504730A JP 2010532657 A JP2010532657 A JP 2010532657A
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seq
amino acids
antigen
nucleic acid
klebsiella
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Japanese (ja)
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JP2010532657A5 (enExample
Inventor
シャーミラ バクシ
トマス シップス
マルクス ハナー
ジュッタ ピカロ
クリスティーナ サッケ
エスター ナージ
アーバン ランドバーグ
ダグマー ツィーレル
アンドリアス メインケ
ビルギット ノイジス
ウルリケ シュティーアシュナイダー
ガバイン アレクサンダー ボン
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インターセル アーゲー
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Publication of JP2010532657A publication Critical patent/JP2010532657A/ja
Publication of JP2010532657A5 publication Critical patent/JP2010532657A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26Klebsiella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0266Klebsiella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2010504730A 2007-05-02 2008-04-29 クレブシエラ属の抗原 Pending JP2010532657A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07107344 2007-05-02
PCT/EP2008/055214 WO2008135446A2 (en) 2007-05-02 2008-04-29 Klebsiella antigens

Publications (2)

Publication Number Publication Date
JP2010532657A true JP2010532657A (ja) 2010-10-14
JP2010532657A5 JP2010532657A5 (enExample) 2011-07-14

Family

ID=39708006

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010504730A Pending JP2010532657A (ja) 2007-05-02 2008-04-29 クレブシエラ属の抗原

Country Status (7)

Country Link
US (3) US8236326B2 (enExample)
EP (5) EP2152731A2 (enExample)
JP (1) JP2010532657A (enExample)
CN (1) CN102015754A (enExample)
AU (1) AU2008248755A1 (enExample)
CA (1) CA2685805A1 (enExample)
WO (1) WO2008135446A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2685805A1 (en) * 2007-05-02 2008-11-13 Intercell Ag Klebsiella antigens
AU2009287339B2 (en) * 2008-08-28 2015-11-26 The University Of Queensland Mutant bacterial glycoproteins and uses thereof
WO2013112696A1 (en) * 2012-01-27 2013-08-01 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Compositions and methods for immunization against bacteria expressing a carbapenemase
KR101605846B1 (ko) * 2013-11-20 2016-03-23 한국과학기술연구원 클렙시엘라 뉴모니아에 특이적으로 결합하는 단일가닥 핵산 앱타머 및 이를 이용한 클렙시엘라 뉴모니아 검출 방법
EP3485907B1 (en) * 2015-01-12 2023-06-28 Evaxion Biotech ApS Treatment and prophylaxis of k. pneumoniae infection
US11000582B2 (en) 2015-07-10 2021-05-11 Epitopix, Llc Proteins and immunizing compositions containing klebsiella proteins and methods of use
JP2018527924A (ja) * 2015-08-24 2018-09-27 メディミューン,エルエルシー Mrkaポリペプチド、抗体、およびその使用
CN108699137A (zh) * 2015-10-28 2018-10-23 阿尔萨尼斯生物科学有限责任公司 靶向基于甘露聚糖的肺炎克雷伯氏菌的o-抗原的抗体
KR20190077306A (ko) 2016-08-05 2019-07-03 메디뮨 엘엘씨 항-o2 항체 및 이의 용도
JP2019531708A (ja) * 2016-08-12 2019-11-07 エックスフォー・ファーマシューティカルズ(オーストリア)ゲーエムべーハー クレブシエラ・ニューモニエo3特異的抗体
CN109843917B (zh) 2016-10-19 2023-10-03 免疫医疗有限责任公司 抗o1抗体及其用途
CN110540595B (zh) * 2018-12-20 2021-04-06 湖北工业大学 一种肺炎克雷伯菌抗体乳胶微球免疫层析检测试纸的制备方法
CN110540599B (zh) * 2018-12-20 2021-04-06 湖北工业大学 基于肺炎克雷伯菌表面蛋白抗体的肺炎克雷伯菌Elisa检测试剂盒及制备方法
CN110540600B (zh) * 2018-12-20 2021-01-29 湖北工业大学 基于肺炎克雷伯菌表面蛋白的乳胶微球免疫层析试纸的制备方法
CN111150839A (zh) * 2019-12-17 2020-05-15 中国科学院深圳先进技术研究院 一种用于免疫接种的组合物及其制备方法
CN112505324A (zh) * 2020-11-06 2021-03-16 杭州迅耀生物科技有限公司 一种新型冠状病毒检测方法
CN116033922B (zh) * 2021-08-25 2025-08-19 北京三诺佳邑生物技术有限责任公司 特异性识别肺炎克雷伯菌o1抗原的抗体及其应用
CN115838431A (zh) * 2022-07-08 2023-03-24 中国人民解放军陆军军医大学 一种用作肺炎克雷伯菌疫苗抗原的融合蛋白KP-Ag2及其应用
WO2025177313A1 (en) * 2024-02-23 2025-08-28 Bharat Serums And Vaccines Limited Antibodies against klebsiella pneumoniae and implementations thereof

Citations (1)

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Publication number Priority date Publication date Assignee Title
US6610836B1 (en) * 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics

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IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
WO1991018088A1 (en) 1990-05-23 1991-11-28 The United States Of America, Represented By The Secretary, United States Department Of Commerce Adeno-associated virus (aav)-based eucaryotic vectors
US5475096A (en) 1990-06-11 1995-12-12 University Research Corporation Nucleic acid ligands
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ATE228529T1 (de) * 1996-08-30 2002-12-15 Jens Peter Fuerste Spiegelselektion und spiegelevolution von nucleinsäuren
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US6610836B1 (en) * 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics

Also Published As

Publication number Publication date
EP2489673A2 (en) 2012-08-22
WO2008135446A3 (en) 2009-03-12
AU2008248755A1 (en) 2008-11-13
CN102015754A (zh) 2011-04-13
US20130230526A9 (en) 2013-09-05
EP2338902A1 (en) 2011-06-29
WO2008135446A2 (en) 2008-11-13
EP2360177A1 (en) 2011-08-24
US20110236410A1 (en) 2011-09-29
EP2489673A3 (en) 2012-09-12
EP2338902A8 (en) 2011-08-03
US8637052B2 (en) 2014-01-28
EP2152731A2 (en) 2010-02-17
EP2497779A1 (en) 2012-09-12
US20140212448A1 (en) 2014-07-31
US8236326B2 (en) 2012-08-07
US20130011403A1 (en) 2013-01-10
CA2685805A1 (en) 2008-11-13

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