CA2685805A1 - Klebsiella antigens - Google Patents

Klebsiella antigens Download PDF

Info

Publication number
CA2685805A1
CA2685805A1 CA002685805A CA2685805A CA2685805A1 CA 2685805 A1 CA2685805 A1 CA 2685805A1 CA 002685805 A CA002685805 A CA 002685805A CA 2685805 A CA2685805 A CA 2685805A CA 2685805 A1 CA2685805 A1 CA 2685805A1
Authority
CA
Canada
Prior art keywords
seq
amino acids
antigen
nucleic acid
pneumoniae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002685805A
Other languages
English (en)
French (fr)
Inventor
Sharmila Bakshi
Thomas Cipps
Markus Hanner
Jutta Pikalo
Christina Satke
Eszter Nagy
Urban Lundberg
Dagmar Zierer
Andreas Meinke
Birgit Noiges
Ulrike Stierschneider
Alexander Von Gabain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valneva Austria GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2685805A1 publication Critical patent/CA2685805A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26Klebsiella (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0266Klebsiella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1228Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002685805A 2007-05-02 2008-04-29 Klebsiella antigens Abandoned CA2685805A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07107344 2007-05-02
EP07107344.9 2007-05-02
PCT/EP2008/055214 WO2008135446A2 (en) 2007-05-02 2008-04-29 Klebsiella antigens

Publications (1)

Publication Number Publication Date
CA2685805A1 true CA2685805A1 (en) 2008-11-13

Family

ID=39708006

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002685805A Abandoned CA2685805A1 (en) 2007-05-02 2008-04-29 Klebsiella antigens

Country Status (7)

Country Link
US (3) US8236326B2 (enExample)
EP (5) EP2152731A2 (enExample)
JP (1) JP2010532657A (enExample)
CN (1) CN102015754A (enExample)
AU (1) AU2008248755A1 (enExample)
CA (1) CA2685805A1 (enExample)
WO (1) WO2008135446A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2152731A2 (en) * 2007-05-02 2010-02-17 Intercell AG Klebsiella antigens
AU2009287339B2 (en) * 2008-08-28 2015-11-26 The University Of Queensland Mutant bacterial glycoproteins and uses thereof
WO2013112696A1 (en) * 2012-01-27 2013-08-01 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Compositions and methods for immunization against bacteria expressing a carbapenemase
KR101605846B1 (ko) * 2013-11-20 2016-03-23 한국과학기술연구원 클렙시엘라 뉴모니아에 특이적으로 결합하는 단일가닥 핵산 앱타머 및 이를 이용한 클렙시엘라 뉴모니아 검출 방법
EP4279080A3 (en) * 2015-01-12 2024-02-21 Evaxion Biotech A/S Treatment and prophylaxis of k. pneumoniae infection
CA2991907A1 (en) * 2015-07-10 2017-01-19 Douglas T. Burkhardt Proteins and immunizing compositions containing klebsiella proteins and methods of use
MX2018001964A (es) * 2015-08-24 2018-06-19 Medimmune Llc Polipeptidos mrka, anticuerpos y usos de los mismos.
MX2018005015A (es) * 2015-10-28 2019-06-24 Arsanis Biosciences Gmbh Anticuerpos dirigidos a un antigeno-o de manano de la k. pneumoniae.
SG11201900027XA (en) * 2016-08-05 2019-02-27 Medimmune Llc Anti-o2 antibodies and uses thereof
EP3497124A1 (en) 2016-08-12 2019-06-19 ARSANIS Biosciences GmbH Klebsiella pneumoniae o3 specific antibodies
WO2018075375A1 (en) * 2016-10-19 2018-04-26 Medimmune, Llc Anti-o1 antibodies and uses thereof
CN110540599B (zh) * 2018-12-20 2021-04-06 湖北工业大学 基于肺炎克雷伯菌表面蛋白抗体的肺炎克雷伯菌Elisa检测试剂盒及制备方法
CN110540600B (zh) * 2018-12-20 2021-01-29 湖北工业大学 基于肺炎克雷伯菌表面蛋白的乳胶微球免疫层析试纸的制备方法
CN110540595B (zh) * 2018-12-20 2021-04-06 湖北工业大学 一种肺炎克雷伯菌抗体乳胶微球免疫层析检测试纸的制备方法
CN111150839A (zh) * 2019-12-17 2020-05-15 中国科学院深圳先进技术研究院 一种用于免疫接种的组合物及其制备方法
CN112505324A (zh) * 2020-11-06 2021-03-16 杭州迅耀生物科技有限公司 一种新型冠状病毒检测方法
CN116033922B (zh) * 2021-08-25 2025-08-19 北京三诺佳邑生物技术有限责任公司 特异性识别肺炎克雷伯菌o1抗原的抗体及其应用
CN115838431A (zh) * 2022-07-08 2023-03-24 中国人民解放军陆军军医大学 一种用作肺炎克雷伯菌疫苗抗原的融合蛋白KP-Ag2及其应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
WO1991018088A1 (en) 1990-05-23 1991-11-28 The United States Of America, Represented By The Secretary, United States Department Of Commerce Adeno-associated virus (aav)-based eucaryotic vectors
KR970002255B1 (ko) 1990-06-11 1997-02-26 넥스스타 파아마슈티컬드, 인크. 핵산 리간드
DK0464533T3 (da) 1990-06-28 1999-04-26 Gen Hospital Corp Fusionsproteiner med immunglobulindele, deres fremstilling og anvendelse
EP0772619B2 (en) 1994-07-15 2010-12-08 The University of Iowa Research Foundation Immunomodulatory oligonucleotides
RS50101B (sr) 1996-02-24 2009-01-22 Boehringer Ingelheim International Gmbh., Farmaceutski preparati za imunomodulaciju
JP2001504448A (ja) 1996-08-30 2001-04-03 フュルステ,イェンス,ペーター 核酸の鏡面対称選択および進化
US5849902A (en) 1996-09-26 1998-12-15 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
US6958239B2 (en) 1996-11-21 2005-10-25 Oligos Etc Inc. Three component chimeric antisense oligonucleotides
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
DE19803453A1 (de) 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
US6610836B1 (en) * 1999-01-29 2003-08-26 Genome Therapeutics Corporation Nucleic acid amino acid sequences relating to Klebsiella pneumoniae for diagnostics and therapeutics
AT408721B (de) 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
AT409085B (de) 2000-01-28 2002-05-27 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
WO2001078767A2 (en) 2000-04-14 2001-10-25 Cistem Biotechnologies Gmbh Pharmaceutical preparations comprising modified peptides
AT410173B (de) 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung
RU2413520C2 (ru) 2000-06-08 2011-03-10 Интерселл Аг Вакцинная композиция, содержащая иммуностимулирующие олигодезоксинуклеотиды
CA2418854A1 (en) 2000-08-17 2002-02-21 Jorg Fritz A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof
AT410635B (de) 2000-10-18 2003-06-25 Cistem Biotechnologies Gmbh Vakzin-zusammensetzung
EP1390495B1 (en) 2001-05-21 2007-07-04 Intercell AG Immunostimulatory oligodeoxynucleic molecules
WO2003047602A1 (en) 2001-12-07 2003-06-12 Intercell Ag Immunostimulatory oligodeoxynucleotides
WO2005103073A2 (en) * 2004-04-27 2005-11-03 Intercell Ag Td antigens
EP2152731A2 (en) * 2007-05-02 2010-02-17 Intercell AG Klebsiella antigens
DE102012005675A1 (de) 2012-03-21 2013-09-26 Daimler Ag Kraftfahrzeugantriebsstrangvorrichtung mit einem Mehrgruppengetriebe

Also Published As

Publication number Publication date
EP2338902A8 (en) 2011-08-03
EP2360177A1 (en) 2011-08-24
WO2008135446A3 (en) 2009-03-12
WO2008135446A2 (en) 2008-11-13
US20110236410A1 (en) 2011-09-29
EP2497779A1 (en) 2012-09-12
US20130011403A1 (en) 2013-01-10
EP2489673A3 (en) 2012-09-12
US8637052B2 (en) 2014-01-28
EP2152731A2 (en) 2010-02-17
CN102015754A (zh) 2011-04-13
US20130230526A9 (en) 2013-09-05
JP2010532657A (ja) 2010-10-14
US8236326B2 (en) 2012-08-07
EP2338902A1 (en) 2011-06-29
AU2008248755A1 (en) 2008-11-13
EP2489673A2 (en) 2012-08-22
US20140212448A1 (en) 2014-07-31

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140429