JP2010532656A5 - - Google Patents
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- Publication number
- JP2010532656A5 JP2010532656A5 JP2009545705A JP2009545705A JP2010532656A5 JP 2010532656 A5 JP2010532656 A5 JP 2010532656A5 JP 2009545705 A JP2009545705 A JP 2009545705A JP 2009545705 A JP2009545705 A JP 2009545705A JP 2010532656 A5 JP2010532656 A5 JP 2010532656A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- fusion protein
- nucleic acid
- acid molecule
- immunogenic composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000037240 fusion proteins Human genes 0.000 claims 3
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 229960005486 vaccines Drugs 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000000240 adjuvant Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000003308 immunostimulating Effects 0.000 claims 1
Claims (6)
- LVL068（配列番号８１）；LVL155（配列番号９３）；LVL078（配列番号８５）；およびLVL157（配列番号９７）からなる群から選択される構築物を含む融合タンパク質。
- 請求項１に記載の融合タンパク質をコードする核酸分子。
- 請求項２に記載の核酸分子を含むベクター。
- 請求項３に記載のベクターで形質転換された宿主細胞。
- 請求項１に記載の融合タンパク質を含み、アジュバント、および/または免疫賦活性サイトカインまたはケモカインをさらに含む、免疫原性組成物またはワクチン。
- 医療において使用するための、請求項５に記載の免疫原性組成物またはワクチン。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0700759A GB0700759D0 (en) | 2007-01-15 | 2007-01-15 | Novel fusion protein |
| US91484807P | 2007-04-30 | 2007-04-30 | |
| US91492507P | 2007-04-30 | 2007-04-30 | |
| GB0709707A GB0709707D0 (en) | 2007-05-21 | 2007-05-21 | Novel fusion protein |
| PCT/US2008/050879 WO2008089074A2 (en) | 2007-01-15 | 2008-01-11 | Fusion proteins comprising the tumor rejection antigens ny-eso-1 and lage-1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010532656A JP2010532656A (ja) | 2010-10-14 |
| JP2010532656A5 true JP2010532656A5 (ja) | 2011-02-24 |
Family
ID=41111108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009545705A Pending JP2010532656A (ja) | 2007-01-15 | 2008-01-11 | 癌退縮抗原ｎｙ−ｅｓｏ−１およびｌａｇｅ−１を含む融合タンパク質 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2118128B1 (ja) |
| JP (1) | JP2010532656A (ja) |
| KR (1) | KR20090122426A (ja) |
| BR (1) | BRPI0806501A2 (ja) |
| CA (1) | CA2674458A1 (ja) |
| DK (1) | DK2118128T3 (ja) |
| EA (1) | EA016818B1 (ja) |
| ES (1) | ES2398492T3 (ja) |
| HR (1) | HRP20130022T1 (ja) |
| MX (1) | MX2009007572A (ja) |
| PE (1) | PE20081687A1 (ja) |
| PL (1) | PL2118128T3 (ja) |
| SI (1) | SI2118128T1 (ja) |
| TW (1) | TW200902049A (ja) |
| WO (1) | WO2008089074A2 (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008308474A (ja) * | 2007-06-18 | 2008-12-25 | Nitto Denko Corp | 抗原ペプチド製剤の調製方法 |
| KR20120002534A (ko) | 2009-03-17 | 2012-01-05 | 엠디엑스헬스 에스에이 | 유전자 발현의 향상된 검출 |
| GB0910046D0 (en) | 2009-06-10 | 2009-07-22 | Glaxosmithkline Biolog Sa | Novel compositions |
| CA2847332A1 (en) * | 2011-08-31 | 2013-03-07 | Mie University | Vaccine preparation for cancer treatment |
| GB201116248D0 (en) | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
| CN105555756B (zh) * | 2013-06-28 | 2018-12-07 | 奥克兰联合服务有限公司 | 氨基酸缀合物和肽缀合物及缀合方法 |
| JP6558699B2 (ja) | 2013-10-01 | 2019-08-14 | 国立大学法人三重大学 | 抗原提示を促進するエピトープ間配列を含むｔ細胞誘導ワクチン |
| JP2018505152A (ja) | 2014-12-23 | 2018-02-22 | アン ブリンブル マーガレット | アミノ酸複合体及びペプチド複合体ならびにそれらの使用 |
| KR20180128915A (ko) | 2016-02-26 | 2018-12-04 | 오클랜드 유니서비시즈 리미티드 | 아미노산 및 펩티드 접합체 및 접합 방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06205672A (ja) * | 1992-03-19 | 1994-07-26 | Nippon Zeon Co Ltd | 日本脳炎ウイルス及びｂ型肝炎ウイルスの表面抗原タンパク質の抗原部位を持つキメラタンパク質の製造法、およびそれに用いる組み換えバキュロウイルス |
| US6686147B1 (en) * | 1998-07-15 | 2004-02-03 | Ludwig Institute For Cancer Research | Cancer associated antigens and uses therefor |
| PT1272633E (pt) * | 2000-03-30 | 2011-06-27 | Dendreon Corp | Composições e métodos para imunoterapia baseada em células dendríticas |
| US20030044813A1 (en) * | 2001-03-30 | 2003-03-06 | Old Lloyd J. | Cancer-testis antigens |
| EP1708741B1 (en) * | 2003-12-24 | 2016-03-30 | Aduro Biotech | Recombinant nucleic acid molecules encoding fusion proteins comprising antigens and bacterial secretory signal polypeptides, expression cassettes, and bacteria, and methods of use thereof |
| GB0409940D0 (en) * | 2004-05-04 | 2004-06-09 | Glaxosmithkline Biolog Sa | Vaccine |
| NZ555907A (en) * | 2004-11-16 | 2009-12-24 | Aeras Global Tb Vaccine Found | Multivalent vaccines comprising recombinant viral vectors |
| CA2653402A1 (en) * | 2006-05-26 | 2007-12-06 | Glaxosmithkline Biologicals S.A. | Method |
| AU2008207025B2 (en) * | 2007-01-15 | 2012-08-23 | Glaxosmithkline Biologicals Sa | Vaccine |
-
2008
- 2008-01-11 TW TW097101220A patent/TW200902049A/zh unknown
- 2008-01-11 EP EP08727588A patent/EP2118128B1/en not_active Not-in-force
- 2008-01-11 PL PL08727588T patent/PL2118128T3/pl unknown
- 2008-01-11 DK DK08727588.9T patent/DK2118128T3/da active
- 2008-01-11 SI SI200830870T patent/SI2118128T1/sl unknown
- 2008-01-11 BR BRPI0806501-2A2A patent/BRPI0806501A2/pt not_active IP Right Cessation
- 2008-01-11 KR KR1020097016892A patent/KR20090122426A/ko not_active Application Discontinuation
- 2008-01-11 JP JP2009545705A patent/JP2010532656A/ja active Pending
- 2008-01-11 CA CA002674458A patent/CA2674458A1/en not_active Abandoned
- 2008-01-11 ES ES08727588T patent/ES2398492T3/es active Active
- 2008-01-11 EA EA200900738A patent/EA016818B1/ru not_active IP Right Cessation
- 2008-01-11 WO PCT/US2008/050879 patent/WO2008089074A2/en active Application Filing
- 2008-01-11 PE PE2008000128A patent/PE20081687A1/es not_active Application Discontinuation
- 2008-01-11 MX MX2009007572A patent/MX2009007572A/es active IP Right Grant
-
2013
- 2013-01-14 HR HRP20130022AT patent/HRP20130022T1/hr unknown
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