JP2010532173A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010532173A5 JP2010532173A5 JP2010515226A JP2010515226A JP2010532173A5 JP 2010532173 A5 JP2010532173 A5 JP 2010532173A5 JP 2010515226 A JP2010515226 A JP 2010515226A JP 2010515226 A JP2010515226 A JP 2010515226A JP 2010532173 A5 JP2010532173 A5 JP 2010532173A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- pluripotent
- cell
- population
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims description 122
- 238000000034 method Methods 0.000 claims description 60
- 239000007788 liquid Substances 0.000 claims description 26
- 102000035195 Peptidases Human genes 0.000 claims description 25
- 108091005804 Peptidases Proteins 0.000 claims description 25
- 239000002609 medium Substances 0.000 claims description 25
- 239000001963 growth medium Substances 0.000 claims description 22
- 239000003112 inhibitor Substances 0.000 claims description 20
- 238000000926 separation method Methods 0.000 claims description 19
- 108091000080 Phosphotransferase Proteins 0.000 claims description 14
- 102000020233 phosphotransferase Human genes 0.000 claims description 14
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims description 9
- 238000004113 cell culture Methods 0.000 claims description 9
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims description 9
- 238000004891 communication Methods 0.000 claims description 8
- 238000013019 agitation Methods 0.000 claims description 7
- 230000012010 growth Effects 0.000 claims description 6
- 229940122618 Trypsin inhibitor Drugs 0.000 claims description 5
- 101710162629 Trypsin inhibitor Proteins 0.000 claims description 5
- VVBXXVAFSPEIJQ-CVIPOMFBSA-N [(2r)-3-[[(2r)-1-[[(2s,5r,8r,11r,12s,15s,18s,21s)-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-5-[(4-hydroxyphenyl)methyl]-4,11-dimethyl-2-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]am Chemical compound C([C@@H]1C(=O)N[C@@H](C(=O)O[C@H](C)[C@@H](C(N[C@@H](CCCN=C(N)N)C(=O)N[C@H]2CC[C@H](O)N(C2=O)[C@@H](CC(C)C)C(=O)N1C)=O)NC(=O)[C@H](NC(=O)[C@H](O)COS(O)(=O)=O)CC(C)C)C(C)C)C1=CC=C(O)C=C1 VVBXXVAFSPEIJQ-CVIPOMFBSA-N 0.000 claims description 5
- 230000010261 cell growth Effects 0.000 claims description 5
- 239000002753 trypsin inhibitor Substances 0.000 claims description 5
- 102000004142 Trypsin Human genes 0.000 claims description 4
- 108090000631 Trypsin Proteins 0.000 claims description 4
- 230000004069 differentiation Effects 0.000 claims description 4
- 238000012423 maintenance Methods 0.000 claims description 4
- 230000035755 proliferation Effects 0.000 claims description 4
- 239000012588 trypsin Substances 0.000 claims description 4
- 102000004190 Enzymes Human genes 0.000 claims description 3
- 108090000790 Enzymes Proteins 0.000 claims description 3
- 235000010469 Glycine max Nutrition 0.000 claims description 3
- 244000068988 Glycine max Species 0.000 claims description 3
- 239000004365 Protease Substances 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 210000005260 human cell Anatomy 0.000 claims description 2
- 238000010899 nucleation Methods 0.000 claims description 2
- 210000001778 pluripotent stem cell Anatomy 0.000 claims description 2
- 235000019833 protease Nutrition 0.000 claims description 2
- 235000019419 proteases Nutrition 0.000 claims description 2
- 230000001810 trypsinlike Effects 0.000 claims description 2
- 102000000568 rho-Associated Kinases Human genes 0.000 claims 9
- 108010041788 rho-Associated Kinases Proteins 0.000 claims 9
- ADDJDJQFPKUMAF-SFHVURJKSA-N (4s)-5-amino-5-oxo-4-[[4-(4-phenylthiophen-2-yl)benzoyl]amino]pentanoic acid Chemical compound C1=CC(C(=O)N[C@@H](CCC(O)=O)C(=O)N)=CC=C1C1=CC(C=2C=CC=CC=2)=CS1 ADDJDJQFPKUMAF-SFHVURJKSA-N 0.000 claims 1
- 229940121649 protein inhibitor Drugs 0.000 claims 1
- 239000012268 protein inhibitor Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000011435 rock Substances 0.000 description 9
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94701307P | 2007-06-29 | 2007-06-29 | |
| US60/947,013 | 2007-06-29 | ||
| PCT/US2008/068814 WO2009006422A1 (en) | 2007-06-29 | 2008-06-30 | Automated method and apparatus for embryonic stem cell culture |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014063625A Division JP2014110817A (ja) | 2007-06-29 | 2014-03-26 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016125186A Division JP2016168056A (ja) | 2007-06-29 | 2016-06-24 | 胚性幹細胞培養のための自動化された方法および装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010532173A JP2010532173A (ja) | 2010-10-07 |
| JP2010532173A5 true JP2010532173A5 (https=) | 2012-07-26 |
| JP5991796B2 JP5991796B2 (ja) | 2016-09-14 |
Family
ID=39672032
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515226A Active JP5991796B2 (ja) | 2007-06-29 | 2008-06-30 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2014063625A Pending JP2014110817A (ja) | 2007-06-29 | 2014-03-26 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016125186A Pending JP2016168056A (ja) | 2007-06-29 | 2016-06-24 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016217785A Pending JP2017023158A (ja) | 2007-06-29 | 2016-11-08 | 胚性幹細胞培養のための自動化された方法および装置 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014063625A Pending JP2014110817A (ja) | 2007-06-29 | 2014-03-26 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016125186A Pending JP2016168056A (ja) | 2007-06-29 | 2016-06-24 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016217785A Pending JP2017023158A (ja) | 2007-06-29 | 2016-11-08 | 胚性幹細胞培養のための自動化された方法および装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8815585B2 (https=) |
| EP (2) | EP2173863B1 (https=) |
| JP (4) | JP5991796B2 (https=) |
| KR (2) | KR20160005142A (https=) |
| AU (1) | AU2008272949B2 (https=) |
| CA (1) | CA2691793A1 (https=) |
| DK (2) | DK3293256T3 (https=) |
| WO (1) | WO2009006422A1 (https=) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007026353A2 (en) | 2005-08-29 | 2007-03-08 | Technion Research & Development Foundation Ltd. | Media for culturing stem cells |
| EP2059586B1 (en) | 2006-08-02 | 2016-07-20 | Technion Research & Development Foundation Ltd. | Methods of expanding embryonic stem cells in a suspension culture |
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| CA3114827C (en) | 2007-07-31 | 2023-09-05 | Lifescan, Inc. | Differentiation of human embryonic stem cells to pancreatic endocrine |
| KR101731474B1 (ko) | 2008-02-21 | 2017-05-11 | 얀센 바이오테크 인코포레이티드 | 세포 부착, 배양 및 탈리를 위한 방법, 표면 개질 플레이트 및 조성물 |
| US8691565B2 (en) | 2008-03-05 | 2014-04-08 | Terumo Bct, Inc. | Method of reseeding adherent cells grown in a hollow fiber bioreactor system |
| US8828720B2 (en) | 2008-03-17 | 2014-09-09 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US9458431B2 (en) | 2008-03-17 | 2016-10-04 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US8691569B2 (en) | 2008-03-17 | 2014-04-08 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| SG188918A1 (https=) | 2008-03-17 | 2013-04-30 | Agency Science Tech & Res | |
| SG188904A1 (en) | 2008-03-17 | 2013-04-30 | Scripps Research Inst | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
| PL2310492T3 (pl) | 2008-06-30 | 2015-12-31 | Janssen Biotech Inc | Różnocowanie pluripotencjalnych komórek macierzystych |
| EP2295538B1 (en) * | 2008-07-07 | 2015-10-21 | Takara Bio Inc. | Method for production of pluripotent stem cell |
| ES2584053T3 (es) | 2008-11-20 | 2016-09-23 | Janssen Biotech, Inc. | Métodos y composiciones para la unión de células y cultivo en sustratos planos |
| ES2642070T3 (es) | 2008-11-20 | 2017-11-15 | Janssen Biotech, Inc. | Cultivo de células madre pluripotentes en microportadores |
| BRPI0922572A2 (pt) | 2008-12-17 | 2019-09-24 | Scripps Research Inst | método para cultivar células pluripotentes, cultura de células de mamífero pluripotentes, meio de cultura de célula, célula animal pluripotente isolada, e, método para aumentar a pluripotência de uma célula de mamífero. |
| EP2398897B1 (en) | 2009-02-20 | 2017-06-28 | Cellular Dynamics International, Inc. | Methods and compositions for the differentiation of stem cells |
| US9150829B2 (en) | 2009-03-20 | 2015-10-06 | Agency For Science, Technoloy And Research | Culture of pluripotent and multipotent cells on microcarriers |
| KR102058901B1 (ko) | 2009-07-20 | 2019-12-24 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| WO2011043077A1 (ja) * | 2009-10-09 | 2011-04-14 | 川崎重工業株式会社 | 未分化多能性幹細胞の識別方法及び装置並びに自動培養方法及び装置 |
| AU2010306627B2 (en) | 2009-10-16 | 2014-07-17 | The Scripps Research Institute | Induction of pluripotent cells |
| ES2539487T3 (es) | 2009-11-04 | 2015-07-01 | Cellular Dynamics International, Inc. | Reprogramación episómica con compuestos químicos |
| EP3633025B1 (en) | 2009-11-12 | 2022-09-14 | Technion Research & Development Foundation Ltd. | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
| CA2725728C (en) * | 2009-11-24 | 2014-01-28 | University Of Connecticut | Differentiation of human embryonic and induced pluripotent stem cells |
| SG181687A1 (en) | 2009-12-23 | 2012-07-30 | Centocor Ortho Biotech Inc | Differentiation of human embryonic stem cells |
| EP2542667A4 (en) | 2010-03-01 | 2013-07-31 | Janssen Biotech Inc | PROCESS FOR CLEANING CELLS OBTAINED FROM PLURIPOTENTIAL STEM CELLS |
| CA2800498C (en) | 2010-03-31 | 2021-11-16 | The Scripps Research Institute | Reprogramming cells |
| AU2011250651B2 (en) * | 2010-05-05 | 2015-10-08 | Genea Ip Holdings Pty Limited | Media and methods for cell culture |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| JP5696144B2 (ja) | 2010-06-25 | 2015-04-08 | 川崎重工業株式会社 | 多能性幹細胞コロニーの識別方法及び装置並びに多能性幹細胞の自動培養方法及び装置 |
| CN103221536B (zh) | 2010-08-31 | 2016-08-31 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
| CA2810488C (en) | 2010-09-07 | 2025-05-06 | Technion Research & Development Foundation Limited | NEW PROCESSES AND CULTURE MEDIA FOR THE CULTURE OF MULTIPOTENTED STEM CELLS |
| WO2012087965A2 (en) | 2010-12-22 | 2012-06-28 | Fate Therapauetics, Inc. | Cell culture platform for single cell sorting and enhanced reprogramming of ipscs |
| KR101293300B1 (ko) * | 2011-04-05 | 2013-08-09 | (주)로고스바이오시스템스 | 세포의 분리시기를 판정하는 방법과, 이를 이용한 세포의 계대 배양 방법 및 계대 배양 장치 |
| WO2013058403A1 (ja) * | 2011-10-21 | 2013-04-25 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| WO2013082509A1 (en) | 2011-12-01 | 2013-06-06 | The New York Stem Cell Foundation | Automated system for producing induced pluripotent stem cells or differentiated cells |
| US10428309B2 (en) | 2011-12-01 | 2019-10-01 | New York Stem Cell Foundation, Inc. | Systems and methods for producing stem cells and differentiated cells |
| KR102203056B1 (ko) | 2011-12-22 | 2021-01-14 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 단일 인슐린 호르몬 양성 세포로의 분화 |
| CN102604894B (zh) | 2012-02-29 | 2014-07-30 | 中国科学院广州生物医药与健康研究院 | 用于制备神经干细胞的培养基及其用途 |
| AU2013271581B2 (en) | 2012-06-08 | 2018-08-09 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endocrine cells |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| BR112015015770A2 (pt) | 2012-12-31 | 2017-07-11 | Janssen Biotech Inc | cultivo de células-tronco embrionárias humanas na interface ar-líquido para diferenciação em células pancreáticas endócrinas |
| JP6557147B2 (ja) | 2012-12-31 | 2019-08-07 | ヤンセン バイオテツク，インコーポレーテツド | Ｈｂ９調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| RU2687379C2 (ru) | 2012-12-31 | 2019-05-13 | Янссен Байотек, Инк. | Суспендирование и кластеризация плюрипотентных клеток человека с целью их дифференцировки в панкреатические эндокринные клетки |
| US9790465B2 (en) | 2013-04-30 | 2017-10-17 | Corning Incorporated | Spheroid cell culture well article and methods thereof |
| US10465158B2 (en) | 2013-07-12 | 2019-11-05 | President And Fellows Of Harvard College | Systems and methods for cell culture device interconnection and fluidic device interconnection |
| US10202568B2 (en) | 2013-08-12 | 2019-02-12 | Invivosciences Inc. | Automated cell culture system and method |
| SG11201606934SA (en) | 2014-03-04 | 2016-09-29 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| US10006006B2 (en) | 2014-05-16 | 2018-06-26 | Janssen Biotech, Inc. | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells |
| WO2016028880A1 (en) | 2014-08-19 | 2016-02-25 | Cellular Dynamics International, Inc. | Neural networks formed from cells derived from pluripotent stem cells |
| WO2016044681A1 (en) | 2014-09-18 | 2016-03-24 | North Carolina State University | Mammalian lung spheroids and lung spheroid cells and uses thereof |
| EP3212759A1 (en) | 2014-10-29 | 2017-09-06 | Corning Incorporated | Cell culture insert |
| WO2016069930A1 (en) | 2014-10-29 | 2016-05-06 | Corning Incorporated | Microwell design and fabrication for generation of cell culture aggregates |
| JP6930914B2 (ja) | 2014-10-29 | 2021-09-01 | コーニング インコーポレイテッド | 灌流バイオリアクタ・プラットフォーム |
| AU2015363008B2 (en) | 2014-12-19 | 2021-12-09 | Janssen Biotech, Inc. | Suspension culturing of pluripotent stem cells |
| US9944894B2 (en) | 2015-01-16 | 2018-04-17 | General Electric Company | Pluripotent stem cell expansion and passage using a rocking platform bioreactor |
| EP3315604A4 (en) * | 2015-06-25 | 2018-12-26 | Kaneka Corporation | Liquid injection method |
| WO2017007278A1 (ko) * | 2015-07-09 | 2017-01-12 | 사회복지법인 삼성생명공익재단 | 자동 세포 배양기 및 그 배양기의 동작 방법 |
| CN108138130A (zh) | 2015-08-31 | 2018-06-08 | 爱平世股份有限公司 | 多能干细胞制造系统和生产诱导多能干细胞的方法 |
| AU2016331926B2 (en) | 2015-10-01 | 2021-12-09 | Berkeley Lights, Inc. | Well-plate incubator |
| SG10202111851YA (en) | 2015-10-16 | 2021-12-30 | Fate Therapeutics Inc | Platform for the Induction & Maintenance of Ground State Pluripotency |
| CN109069870B (zh) | 2016-02-24 | 2022-04-29 | 洛克菲勒大学 | 基于胚胎细胞的用于亨廷顿氏病的治疗候选物筛选系统、模型及它们的应用 |
| JP6943449B2 (ja) * | 2016-03-21 | 2021-09-29 | グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー | 撹拌タンクバイオリアクタを用いた多能性幹細胞の増殖および継代 |
| DK3443073T3 (da) | 2016-04-14 | 2024-09-02 | Janssen Biotech Inc | Differentiering af pluripotente stamceller til intestinale mellemtarmendodermceller |
| JP2018000130A (ja) * | 2016-07-05 | 2018-01-11 | 株式会社Ihi | 細胞培養装置 |
| KR102711870B1 (ko) * | 2016-07-19 | 2024-10-02 | 아셀라타 리미티드 | 현탁 내 만능줄기세포를 배양하기 위한 배양 배지 |
| DE102016114043B3 (de) | 2016-07-29 | 2017-08-10 | Technische Universität Dresden | Vorrichtung zur Isolierung von Stammzellen aus fötalen Geweben |
| WO2018044699A1 (en) | 2016-08-27 | 2018-03-08 | 3D Biotek, Llc | Bioreactor |
| EP3538644B1 (en) * | 2016-11-10 | 2021-12-29 | Becton, Dickinson and Company | Timeline system for monitoring a culture media protocol |
| CA3045898A1 (en) * | 2016-12-01 | 2018-06-07 | Berkeley Lights, Inc. | Well-plate incubator |
| US20190382706A1 (en) * | 2017-02-27 | 2019-12-19 | Koji Tanabe | Somatic cell production system |
| CN115247129A (zh) * | 2017-02-27 | 2022-10-28 | 田边刚士 | 细胞处理装置 |
| EP3652290B1 (en) | 2017-07-14 | 2022-05-04 | Corning Incorporated | 3d cell culture vessels for manual or automatic media exchange |
| JP7197557B2 (ja) | 2017-07-14 | 2022-12-27 | コーニング インコーポレイテッド | 多孔性支持体を有する細胞培養槽 |
| JP7195302B2 (ja) | 2017-07-14 | 2022-12-23 | コーニング インコーポレイテッド | ３ｄ培養のための細胞培養容器及び３ｄ細胞の培養方法 |
| US11857970B2 (en) | 2017-07-14 | 2024-01-02 | Corning Incorporated | Cell culture vessel |
| KR102220125B1 (ko) * | 2018-04-26 | 2021-02-25 | (주)세포바이오 | 세포배양 자동화 장치 및 방법 |
| WO2020013847A1 (en) | 2018-07-13 | 2020-01-16 | Corning Incorporated | Microcavity dishes with sidewall including liquid medium delivery surface |
| CN111065725B (zh) | 2018-07-13 | 2024-03-29 | 康宁股份有限公司 | 包括具有互联的壁的微板的流体装置 |
| WO2020013845A1 (en) | 2018-07-13 | 2020-01-16 | Corning Incorporated | Cell culture vessels with stabilizer devices |
| US20230035127A1 (en) * | 2021-07-21 | 2023-02-02 | University Of Maryland, College Park | Culture and differentiation of pluripotent stem cells |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4284412A (en) | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
| JPS58155087A (ja) * | 1982-03-12 | 1983-09-14 | Olympus Optical Co Ltd | 細胞の自動培養装置 |
| US4498766A (en) | 1982-03-25 | 1985-02-12 | Becton, Dickinson And Company | Light beam focal spot elongation in flow cytometry devices |
| US4661913A (en) | 1984-09-11 | 1987-04-28 | Becton, Dickinson And Company | Apparatus and method for the detection and classification of articles using flow cytometry techniques |
| US4767206A (en) | 1984-12-24 | 1988-08-30 | Flow Cytometry Standards Corporation | Calibration method for flow cytometry using fluorescent microbeads and synthesis thereof |
| US4774189A (en) | 1984-12-24 | 1988-09-27 | Flow Cytometry Standards Corp. | Fluorescent calibration microbeads simulating stained cells |
| US4857451A (en) | 1984-12-24 | 1989-08-15 | Flow Cytometry Standards Corporation | Method of compensating and calibrating a flow cytometer, and microbead standards kit therefor |
| US4989977A (en) | 1985-07-29 | 1991-02-05 | Becton, Dickinson And Company | Flow cytometry apparatus with improved light beam adjustment |
| US4714682A (en) | 1985-12-11 | 1987-12-22 | Flow Cytometry Standards Corporation | Fluorescent calibration microbeads simulating stained cells |
| US5160974A (en) | 1990-06-25 | 1992-11-03 | Flow Science, Inc. | Closed sample cell for use in flow cytometry |
| US5478722A (en) | 1991-02-17 | 1995-12-26 | The Curators Of The University Of Missouri | Preserved cell preparations for flow cytometry and immunology |
| JP3246664B2 (ja) | 1993-01-29 | 2002-01-15 | ニュー ブルンズウイック サイエンティフィック カンパニー インコーポレイテッド | 足場および懸濁細胞の培養方法並びにその装置 |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6325114B1 (en) | 2000-02-01 | 2001-12-04 | Incyte Genomics, Inc. | Pipetting station apparatus |
| WO2003087292A2 (en) * | 2002-04-08 | 2003-10-23 | Millenium Biologix Inc. | Automated tissue engineering system |
| DE102004043256B4 (de) | 2004-09-07 | 2013-09-19 | Rheinische Friedrich-Wilhelms-Universität Bonn | Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension |
| CN101052712A (zh) | 2004-09-08 | 2007-10-10 | 威斯康星校友研究基金会 | 培养人胚胎干细胞 |
| US20060198827A1 (en) * | 2005-02-04 | 2006-09-07 | Shulamit Levenberg | Engineering vascularized muscle tissue |
| US20060199265A1 (en) * | 2005-03-02 | 2006-09-07 | Wolf Michael F | Seeding implantable medical devices with cells |
-
2008
- 2008-06-30 US US12/164,969 patent/US8815585B2/en active Active
- 2008-06-30 WO PCT/US2008/068814 patent/WO2009006422A1/en not_active Ceased
- 2008-06-30 DK DK17192886.4T patent/DK3293256T3/da active
- 2008-06-30 JP JP2010515226A patent/JP5991796B2/ja active Active
- 2008-06-30 AU AU2008272949A patent/AU2008272949B2/en active Active
- 2008-06-30 CA CA2691793A patent/CA2691793A1/en not_active Abandoned
- 2008-06-30 EP EP08781187.3A patent/EP2173863B1/en active Active
- 2008-06-30 EP EP17192886.4A patent/EP3293256B1/en active Active
- 2008-06-30 DK DK08781187.3T patent/DK2173863T3/en active
- 2008-06-30 KR KR1020157036767A patent/KR20160005142A/ko not_active Ceased
- 2008-06-30 KR KR1020107002003A patent/KR20100059789A/ko not_active Ceased
-
2013
- 2013-03-19 US US13/847,349 patent/US20130316445A1/en not_active Abandoned
-
2014
- 2014-03-26 JP JP2014063625A patent/JP2014110817A/ja active Pending
-
2016
- 2016-06-24 JP JP2016125186A patent/JP2016168056A/ja active Pending
- 2016-11-08 JP JP2016217785A patent/JP2017023158A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010532173A5 (https=) | ||
| KR102671098B1 (ko) | 세포 미소구획 및 제조 방법 | |
| Amsterdam et al. | Structural and functional characterization of isolated pancreatic exocrine cells | |
| DK2173863T3 (en) | Automated method and apparatus for embryonic stem cell culture | |
| JP2016168056A5 (https=) | ||
| Stambaugh et al. | Comparative studies of the acrosomal enzymes of rabbit, rhesus monkey, and human spermatozoa | |
| JP2013500724A5 (https=) | ||
| AU2012255724B2 (en) | Passaging and harvesting formulation and method for human pluripotent stem cells | |
| JP2024544563A (ja) | ナイーブ型ウシ胚性幹細胞の誘導 | |
| WO2021116362A1 (en) | Expansion of stem cells in suspension in a bioreactor | |
| JP6054223B2 (ja) | 幹細胞培養装置、幹細胞培養方法 | |
| TWI656214B (zh) | 清洗卵子或受精卵表面的方法 | |
| Chen et al. | Derivation of human embryonic stem cells by immunosurgery | |
| WO2019097946A1 (ja) | 自動培養装置、細胞培養方法 | |
| JP2022158092A (ja) | 馴化細胞作製方法 | |
| JPH05192135A (ja) | 動物細胞の担体からの剥離及び移植方法 | |
| Meng et al. | Derivation and expansion of human embryonic stem cells under xeno-free, defined conditions | |
| WO2015013875A1 (zh) | 一种全能干细胞培养方法 | |
| Meng et al. | Static and Suspension Culture of Human Embryonic Stem Cells | |
| HK1229368B (en) | A method of cleaning the surface of eggs or fertilized eggs |