JP2010531855A5 - - Google Patents
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- JP2010531855A5 JP2010531855A5 JP2010513989A JP2010513989A JP2010531855A5 JP 2010531855 A5 JP2010531855 A5 JP 2010531855A5 JP 2010513989 A JP2010513989 A JP 2010513989A JP 2010513989 A JP2010513989 A JP 2010513989A JP 2010531855 A5 JP2010531855 A5 JP 2010531855A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- compound
- formula
- hydrogen
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 19
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 claims 10
- 229910052739 hydrogen Inorganic materials 0.000 claims 10
- 239000001257 hydrogen Substances 0.000 claims 10
- 125000000547 substituted alkyl group Chemical group 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 150000003254 radicals Chemical class 0.000 claims 6
- 239000002253 acid Substances 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 3
- 125000002877 alkyl aryl group Chemical group 0.000 claims 2
- 150000003862 amino acid derivatives Chemical class 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 125000003277 amino group Chemical group 0.000 claims 2
- 238000003776 cleavage reaction Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229920006395 saturated elastomer Polymers 0.000 claims 2
- 230000007017 scission Effects 0.000 claims 2
- 125000005017 substituted alkenyl group Chemical group 0.000 claims 2
- 125000005415 substituted alkoxy group Chemical group 0.000 claims 2
- 125000003107 substituted aryl group Chemical group 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000005016 Intestinal Neoplasms Diseases 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 201000002313 intestinal cancer Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- -1 unsaturated aliphatic radicals Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07111716 | 2007-07-04 | ||
| PCT/EP2008/058600 WO2009004060A1 (de) | 2007-07-04 | 2008-07-03 | Neue triazenverbindungen zur behandlung von krebs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010531855A JP2010531855A (ja) | 2010-09-30 |
| JP2010531855A5 true JP2010531855A5 (enExample) | 2011-09-08 |
Family
ID=38606533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010513989A Pending JP2010531855A (ja) | 2007-07-04 | 2008-07-03 | ガン治療のための新規なトリアゼン化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8034797B2 (enExample) |
| EP (1) | EP2167459A1 (enExample) |
| JP (1) | JP2010531855A (enExample) |
| KR (1) | KR20100031620A (enExample) |
| CN (2) | CN101796020A (enExample) |
| AU (1) | AU2008270269B2 (enExample) |
| BR (2) | BRPI0814614A2 (enExample) |
| CA (1) | CA2691178A1 (enExample) |
| EA (1) | EA201000141A1 (enExample) |
| MX (1) | MX2010000223A (enExample) |
| NZ (1) | NZ582346A (enExample) |
| TW (1) | TW200908986A (enExample) |
| WO (1) | WO2009004060A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA024381B1 (ru) * | 2011-03-16 | 2016-09-30 | Криэйтив Терапьютикс Гмбх | Замещенные дифенильные производные |
| WO2012130850A1 (de) | 2011-03-31 | 2012-10-04 | Bayer Pharma Aktiengesellschaft | Gewebetargeting mit onkoziden verbrückten diphenylderivaten zur selektiven behandlung von sexualorgantumoren |
| EP2557075A1 (de) | 2011-08-09 | 2013-02-13 | Trin Therapeutics GmbH | Neue Triazenverbindungen zur Behandlung von Krebs |
| EP2758367B1 (de) | 2011-09-23 | 2015-11-18 | DoubleHill GmbH | Neue isocyanat- und isothiocyanat-verbindungen zur behandlung von krebs |
| CN105566153B (zh) * | 2014-10-14 | 2019-05-31 | 中国医学科学院药物研究所 | 偶氮苯衍生物及其制法和药物组合物与用途 |
| CN109776526A (zh) * | 2019-01-23 | 2019-05-21 | 西南医科大学 | 稠环三唑-(磺酰基)三氮烯类衍生物及其合成方法和用途 |
| DE102020125641A1 (de) | 2020-09-25 | 2022-03-31 | Creative Therapeutics Gmbh | Wirkstoffe und Arzneimittel für die Therapie von Viruserkrankungen, insbesondere Corona-Infektionen, insbesondere COVID-19 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1793115A1 (de) * | 1968-08-03 | 1972-02-03 | Bayer Ag | Neue Triazenderivate |
| BE789138A (fr) * | 1971-09-24 | 1973-03-22 | Bayer Ag | Nouveaux derives triazeniques, leur procede de preparation et medicament les contenant |
| DE10324496A1 (de) * | 2003-05-30 | 2004-12-16 | Bayer Healthcare Ag | Targetorientierte Chemotherapie von Tumoren der Sexualorgane |
-
2008
- 2008-07-03 CN CN200880105688A patent/CN101796020A/zh active Pending
- 2008-07-03 JP JP2010513989A patent/JP2010531855A/ja active Pending
- 2008-07-03 US US12/296,475 patent/US8034797B2/en not_active Expired - Fee Related
- 2008-07-03 CA CA2691178A patent/CA2691178A1/en not_active Abandoned
- 2008-07-03 BR BRPI0814614-4A patent/BRPI0814614A2/pt not_active IP Right Cessation
- 2008-07-03 NZ NZ582346A patent/NZ582346A/en not_active IP Right Cessation
- 2008-07-03 EP EP08774712A patent/EP2167459A1/de not_active Withdrawn
- 2008-07-03 KR KR1020107001039A patent/KR20100031620A/ko not_active Withdrawn
- 2008-07-03 CN CN2011103288515A patent/CN102424657A/zh active Pending
- 2008-07-03 WO PCT/EP2008/058600 patent/WO2009004060A1/de not_active Ceased
- 2008-07-03 TW TW097125031A patent/TW200908986A/zh unknown
- 2008-07-03 EA EA201000141A patent/EA201000141A1/ru unknown
- 2008-07-03 BR BRPI0823332-2A patent/BRPI0823332A2/pt not_active IP Right Cessation
- 2008-07-03 MX MX2010000223A patent/MX2010000223A/es active IP Right Grant
- 2008-07-03 AU AU2008270269A patent/AU2008270269B2/en not_active Expired - Fee Related
-
2011
- 2011-08-09 US US13/205,831 patent/US8426390B2/en not_active Expired - Fee Related
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