MX2010000223A - Compuestos de triazina novedosos para el tratamiento de cancer. - Google Patents

Compuestos de triazina novedosos para el tratamiento de cancer.

Info

Publication number
MX2010000223A
MX2010000223A MX2010000223A MX2010000223A MX2010000223A MX 2010000223 A MX2010000223 A MX 2010000223A MX 2010000223 A MX2010000223 A MX 2010000223A MX 2010000223 A MX2010000223 A MX 2010000223A MX 2010000223 A MX2010000223 A MX 2010000223A
Authority
MX
Mexico
Prior art keywords
triazine compounds
treatment
cancer
novel triazine
novel
Prior art date
Application number
MX2010000223A
Other languages
English (en)
Inventor
Jochen Kalbe
Rudolf Reiter
Rster Heinz F
Original Assignee
Trin Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trin Pharma Gmbh filed Critical Trin Pharma Gmbh
Publication of MX2010000223A publication Critical patent/MX2010000223A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/22—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond containing chains of three or more nitrogen atoms with one or more nitrogen-to-nitrogen double bonds
    • C07C245/24—Chains of only three nitrogen atoms, e.g. diazoamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • C07C309/15—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton the nitrogen atom of at least one of the amino groups being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invenci?n se refiere a compuestos de triazina novedosos, a procedimientos para prepararlos, a una composici?n farmac?utica que los comprenden, y al uso de los mismos para el tratamiento de c?nceres en humanos; los compuestos de triazina novedosos son notables, en comparaci?n con los compuestos de triazina conocidos, por eficacia mejorada con simult?neamente toxicidad reducida, es decir, por menos efectos secundarios.
MX2010000223A 2007-07-04 2008-07-03 Compuestos de triazina novedosos para el tratamiento de cancer. MX2010000223A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07111716 2007-07-04
PCT/EP2008/058600 WO2009004060A1 (de) 2007-07-04 2008-07-03 Neue triazenverbindungen zur behandlung von krebs

Publications (1)

Publication Number Publication Date
MX2010000223A true MX2010000223A (es) 2010-04-30

Family

ID=38606533

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010000223A MX2010000223A (es) 2007-07-04 2008-07-03 Compuestos de triazina novedosos para el tratamiento de cancer.

Country Status (13)

Country Link
US (2) US8034797B2 (es)
EP (1) EP2167459A1 (es)
JP (1) JP2010531855A (es)
KR (1) KR20100031620A (es)
CN (2) CN102424657A (es)
AU (1) AU2008270269B2 (es)
BR (2) BRPI0814614A2 (es)
CA (1) CA2691178A1 (es)
EA (1) EA201000141A1 (es)
MX (1) MX2010000223A (es)
NZ (1) NZ582346A (es)
TW (1) TW200908986A (es)
WO (1) WO2009004060A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014515734A (ja) * 2011-03-16 2014-07-03 クリエイティブ セラポーティクス ゲーエムベーハー 置換ジフェニル誘導体
WO2012130850A1 (de) 2011-03-31 2012-10-04 Bayer Pharma Aktiengesellschaft Gewebetargeting mit onkoziden verbrückten diphenylderivaten zur selektiven behandlung von sexualorgantumoren
EP2557075A1 (de) 2011-08-09 2013-02-13 Trin Therapeutics GmbH Neue Triazenverbindungen zur Behandlung von Krebs
RU2014116229A (ru) 2011-09-23 2015-10-27 Даблхил Гмбх Новые соединения изоцианата и изотиоцианата для лечения злокачественных новообразований
CN105566153B (zh) * 2014-10-14 2019-05-31 中国医学科学院药物研究所 偶氮苯衍生物及其制法和药物组合物与用途
CN109776526A (zh) * 2019-01-23 2019-05-21 西南医科大学 稠环三唑-(磺酰基)三氮烯类衍生物及其合成方法和用途
DE102020125641A1 (de) 2020-09-25 2022-03-31 Creative Therapeutics Gmbh Wirkstoffe und Arzneimittel für die Therapie von Viruserkrankungen, insbesondere Corona-Infektionen, insbesondere COVID-19

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793115A1 (de) * 1968-08-03 1972-02-03 Bayer Ag Neue Triazenderivate
BE789138A (fr) * 1971-09-24 1973-03-22 Bayer Ag Nouveaux derives triazeniques, leur procede de preparation et medicament les contenant
DE10324496A1 (de) * 2003-05-30 2004-12-16 Bayer Healthcare Ag Targetorientierte Chemotherapie von Tumoren der Sexualorgane

Also Published As

Publication number Publication date
CN102424657A (zh) 2012-04-25
EA201000141A1 (ru) 2010-06-30
KR20100031620A (ko) 2010-03-23
US20120028927A1 (en) 2012-02-02
AU2008270269B2 (en) 2013-04-04
BRPI0823332A2 (pt) 2013-07-30
EP2167459A1 (de) 2010-03-31
CN101796020A (zh) 2010-08-04
JP2010531855A (ja) 2010-09-30
US8034797B2 (en) 2011-10-11
TW200908986A (en) 2009-03-01
AU2008270269A1 (en) 2009-01-08
NZ582346A (en) 2012-04-27
AU2008270269A2 (en) 2012-04-12
BRPI0814614A2 (pt) 2011-11-29
CA2691178A1 (en) 2009-01-08
WO2009004060A1 (de) 2009-01-08
US20100234327A1 (en) 2010-09-16
US8426390B2 (en) 2013-04-23

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Legal Events

Date Code Title Description
GB Transfer or rights
FG Grant or registration