JP2010526807A5 - - Google Patents

Download PDF

Info

Publication number
JP2010526807A5
JP2010526807A5 JP2010507419A JP2010507419A JP2010526807A5 JP 2010526807 A5 JP2010526807 A5 JP 2010526807A5 JP 2010507419 A JP2010507419 A JP 2010507419A JP 2010507419 A JP2010507419 A JP 2010507419A JP 2010526807 A5 JP2010526807 A5 JP 2010526807A5
Authority
JP
Japan
Prior art keywords
alkyl
group
substituted
halogens
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010507419A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010526807A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/005726 external-priority patent/WO2008137105A1/en
Publication of JP2010526807A publication Critical patent/JP2010526807A/ja
Publication of JP2010526807A5 publication Critical patent/JP2010526807A5/ja
Pending legal-status Critical Current

Links

JP2010507419A 2007-05-07 2008-05-02 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法 Pending JP2010526807A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92794907P 2007-05-07 2007-05-07
PCT/US2008/005726 WO2008137105A1 (en) 2007-05-07 2008-05-02 Method of treatment using fused aromatic compounds having anti-diabetic activity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014002247A Division JP2014088424A (ja) 2007-05-07 2014-01-09 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法

Publications (2)

Publication Number Publication Date
JP2010526807A JP2010526807A (ja) 2010-08-05
JP2010526807A5 true JP2010526807A5 (enExample) 2011-05-26

Family

ID=39943845

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010507419A Pending JP2010526807A (ja) 2007-05-07 2008-05-02 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
JP2014002247A Pending JP2014088424A (ja) 2007-05-07 2014-01-09 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
JP2015145891A Pending JP2015227359A (ja) 2007-05-07 2015-07-23 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2014002247A Pending JP2014088424A (ja) 2007-05-07 2014-01-09 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法
JP2015145891A Pending JP2015227359A (ja) 2007-05-07 2015-07-23 抗糖尿病活性を有する縮合芳香族化合物を用いた治療法

Country Status (6)

Country Link
US (1) US8338458B2 (enExample)
EP (1) EP2155187B1 (enExample)
JP (3) JP2010526807A (enExample)
AU (1) AU2008248186B2 (enExample)
CA (1) CA2688187C (enExample)
WO (1) WO2008137105A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013068486A1 (en) 2011-11-08 2013-05-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the diagnosis and treatment of male infertility
WO2014134772A1 (en) 2013-03-04 2014-09-12 Merck Sharp & Dohme Corp. Compounds inhibiting leucine-rich repeat kinase enzyme activity
US9440952B2 (en) 2013-03-04 2016-09-13 Merck Sharp & Dohme Corp. Compounds inhibiting leucine-rich repeat kinase enzyme activity
WO2014134776A1 (en) 2013-03-04 2014-09-12 Merck Sharp & Dohme Corp. Compounds inhibiting leucine-rich repeat kinase enzyme activity
WO2014134774A1 (en) 2013-03-04 2014-09-12 Merck Sharp & Dohme Corp. Compounds inhibiting leucine-rich repeat kinase enzyme activity
AU2017269335B2 (en) 2016-05-26 2021-07-01 Recurium Ip Holdings, Llc EGFR inhibitor compounds
EP3740207A4 (en) 2018-01-16 2021-10-13 Syros Pharmaceuticals, Inc. CYCLINE-DEPENDENT KINASE 7 (CDK7) INHIBITORS
WO2019143730A1 (en) 2018-01-16 2019-07-25 Syros Pharmaceuticals, Inc. Inhibitors of cyclin-dependent kinase 7 (cdk7)
US12240869B2 (en) 2018-11-01 2025-03-04 Syros Pharmaceuticals, Inc. Inhibitors of cyclin-dependent kinase 7 (CDK7)
WO2021138391A1 (en) 2019-12-30 2021-07-08 Tyra Biosciences, Inc. Indazole compounds
CR20230325A (es) 2020-12-30 2023-12-11 Tyra Biosciences Inc Compuestos de indazol como inhibidores de cinasas

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1856997A (en) 1996-02-02 1997-08-22 Merck & Co., Inc. Method for raising hdl cholesterol levels
ATE236137T1 (de) 1996-02-02 2003-04-15 Merck & Co Inc Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit
CA2386750A1 (en) 1999-10-22 2001-05-03 Merck & Co. Inc. Pharmaceuticals for treating obesity
EP1259494A4 (en) 2000-02-18 2004-09-15 Merck & Co Inc ARYLOXYACETIC ACIDS FOR DIABETES AND LIPID DISORDERS
JP2001354671A (ja) 2000-04-14 2001-12-25 Nippon Chemiphar Co Ltd ペルオキシソーム増殖剤応答性受容体δの活性化剤
JP2004513076A (ja) 2000-07-25 2004-04-30 メルク　エンド　カムパニー　インコーポレーテッド 糖尿病治療で有用なｎ−置換インドール類
US6897231B2 (en) 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
PE20021002A1 (es) 2001-02-02 2002-12-06 Takeda Chemical Industries Ltd Compuestos heterociclicos condensados
US7091230B2 (en) 2001-02-09 2006-08-15 Merck & Co., Inc. 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders
EP1385508B1 (en) 2001-03-27 2008-05-21 Merck & Co., Inc. Dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
US6573287B2 (en) 2001-04-12 2003-06-03 Bristo-Myers Squibb Company 2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
FR2824825B1 (fr) 2001-05-15 2005-05-06 Servier Lab Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE60209348T2 (de) 2001-06-20 2006-10-12 Merck & Co., Inc. Dipeptidylpeptidase-hemmer zur behandlung von diabetes
EP1406872B1 (en) 2001-06-20 2007-12-19 Merck & Co., Inc. Dipeptidyl peptidase inhibitors for the treatment of diabetes
GB0115517D0 (en) 2001-06-25 2001-08-15 Ferring Bv Novel antidiabetic agents
WO2003002593A2 (en) 2001-06-27 2003-01-09 Probiodrug Ag Peptide structures useful for competitive modulation of dipeptidyl peptidase iv catalysis
ATE370943T1 (de) 2001-06-27 2007-09-15 Smithkline Beecham Corp Fluoropyrrolidine als dipeptidyl-peptidase inhibitoren
WO2003002530A2 (en) 2001-06-27 2003-01-09 Smithkline Beecham Corporation Pyrrolidines as dipeptidyl peptidase inhibitors
CN1723196A (zh) 2001-06-27 2006-01-18 史密丝克莱恩比彻姆公司 作为二肽酶抑制剂的氟代吡咯烷
EP1404675B1 (en) 2001-07-03 2008-03-12 Novo Nordisk A/S Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
UA74912C2 (en) 2001-07-06 2006-02-15 Merck & Co Inc Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
US20050107450A1 (en) * 2001-12-21 2005-05-19 Brown Kathleen K. Dosing regimen for ppar-gamma activators
EP1490335B1 (en) 2002-03-25 2007-09-19 Merck & Co., Inc. Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
JP4530852B2 (ja) 2002-07-15 2010-08-25 メルク・シャープ・エンド・ドーム・コーポレイション 糖尿病治療のためのピペリジノピリミジンジペプチジルペプチダーゼ阻害剤
AU2003254852A1 (en) 2002-08-08 2004-02-25 Takeda Pharmaceutical Company Limited Fused heterocyclic compounds as peptidase inhibitors
NZ538031A (en) 2002-08-29 2007-10-26 Merck & Co Inc Indoles having anti-diabetic activity
JP4340232B2 (ja) 2002-08-29 2009-10-07 メルク エンド カムパニー インコーポレーテッド 抗糖尿病活性を有するインドール類
ATE370141T1 (de) 2002-10-07 2007-09-15 Merck & Co Inc Antidiabetische heterocyclische beta- aminoverbindungen als inhibitoren von dipeptidylpeptidase
DK1556362T3 (da) 2002-10-18 2008-06-09 Merck & Co Inc Heterocykliske beta-aminodipeptidylpeptidaseinhibitorer til behandling eller forebyggelse af diabetes
MXPA05004890A (es) 2002-11-07 2005-07-22 Merck & Co Inc Derivados de fenilalanina como inhibidores de dipeptidilpeptidasa para el tratamiento o prevencion de diabetes.
US7737295B2 (en) 2004-04-13 2010-06-15 Merck Sharp & Dohme Corp. CETP inhibitors
DOP2005000123A (es) 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
ATE488236T1 (de) 2004-09-16 2010-12-15 Merck Sharp & Dohme Verbindungen zur behandlung von dyslipidämie und anderer lipidstörungen
DK1848430T3 (da) * 2004-12-31 2017-11-06 Dr Reddys Laboratories Ltd Nye benzylamin-derivativer som cetp-inhibitors
TW200640453A (en) * 2005-01-28 2006-12-01 Lilly Co Eli Formulations and dosing regimen for PPAR-α modulators
WO2006096564A1 (en) * 2005-03-04 2006-09-14 Merck & Co., Inc. Fused aromatic compounds having anti-diabetic activity
EP1858844A4 (en) 2005-03-10 2009-04-22 Merck & Co Inc NEW CRYSTALLINE FORMS OF ANTIDIABETIC COMPOUNDS

Similar Documents

Publication Publication Date Title
JP2005508318A5 (enExample)
TWI376370B (en) Compounds for inflammation and immune-related uses
JP2007514756A5 (enExample)
JP6409004B2 (ja) ソルチリン阻害剤としてのｎ置換された５置換フタルアミド酸
JP2019034943A5 (enExample)
JP2007500720A5 (enExample)
JP2018536648A5 (enExample)
JP2019517487A5 (enExample)
JP2009533410A5 (enExample)
JP2009542717A5 (enExample)
RU2017131875A (ru) Трехъядерные соединения и их применение в медицине
JP2014518853A5 (enExample)
CN101090724A (zh) 用于抑制人硬脂酰CoA去饱和酶的吡啶衍生物
WO2009114994A1 (zh) 哒嗪酮类化合物在制备抗肿瘤药物中的用途
TW200403210A (en) Benzamide derivatives
JP2013500314A5 (enExample)
JP2009513703A5 (enExample)
JP2012507566A5 (enExample)
JP2010529203A5 (enExample)
JP2009531390A5 (enExample)
JP2018516963A5 (enExample)
CA2798610A1 (en) Bicyclic heteroaryl compounds as gpr119 modulators
JP2016508506A5 (enExample)
JP2017538773A5 (enExample)
JP2009530398A5 (enExample)