JP2010526034A5 - - Google Patents
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- Publication number
- JP2010526034A5 JP2010526034A5 JP2010504215A JP2010504215A JP2010526034A5 JP 2010526034 A5 JP2010526034 A5 JP 2010526034A5 JP 2010504215 A JP2010504215 A JP 2010504215A JP 2010504215 A JP2010504215 A JP 2010504215A JP 2010526034 A5 JP2010526034 A5 JP 2010526034A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- dendritic cells
- polynucleotide
- shrna
- desired antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 8
- 102000036639 antigens Human genes 0.000 claims 8
- 108091007433 antigens Proteins 0.000 claims 8
- 210000004443 dendritic cell Anatomy 0.000 claims 8
- 108091027967 Small hairpin RNA Proteins 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 239000004055 small Interfering RNA Substances 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 3
- 230000002708 enhancing effect Effects 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 108091005485 macrophage scavenger receptors Proteins 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 102000014452 scavenger receptors Human genes 0.000 claims 3
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92362807P | 2007-04-16 | 2007-04-16 | |
| US60/923,628 | 2007-04-16 | ||
| PCT/US2008/060479 WO2008131006A2 (en) | 2007-04-16 | 2008-04-16 | Method for inhibiting scavenger receptor-a and increasing immune response to antigens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010526034A JP2010526034A (ja) | 2010-07-29 |
| JP2010526034A5 true JP2010526034A5 (enExample) | 2011-05-19 |
| JP5565906B2 JP5565906B2 (ja) | 2014-08-06 |
Family
ID=39853929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010504215A Expired - Fee Related JP5565906B2 (ja) | 2007-04-16 | 2008-04-16 | スカベンジャー受容体−ａを抑制する方法および抗原への免疫応答を増大する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8133875B2 (enExample) |
| EP (1) | EP2147011A4 (enExample) |
| JP (1) | JP5565906B2 (enExample) |
| CN (1) | CN101675066A (enExample) |
| CA (1) | CA2684278C (enExample) |
| WO (1) | WO2008131006A2 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2790203C (en) * | 2010-02-19 | 2019-05-14 | Norman Latov | Inhibitor of macrophage scavenger receptor 1 (msr1) for the treatment of autoimmune demyelinating diseases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5881000A (en) | 1999-06-24 | 2001-01-09 | Smithkline Beecham Corporation | Macrophage scavenger receptor antagonists |
| GB9927328D0 (en) * | 1999-11-18 | 2000-01-12 | Lorantis Ltd | Immunotherapy |
| WO2003042246A2 (en) * | 2001-11-14 | 2003-05-22 | Lorantis Limited | Inhibitors of the notch signalling pathway for use in the treatment of cancer |
| EP1601374B2 (en) * | 2003-03-12 | 2012-05-23 | Rappaport Family Institute for Research in the Medical Sciences | Compositions and methods for diagnosing and treating an inflammation |
-
2008
- 2008-04-16 WO PCT/US2008/060479 patent/WO2008131006A2/en not_active Ceased
- 2008-04-16 US US12/104,105 patent/US8133875B2/en active Active
- 2008-04-16 CN CN200880012072A patent/CN101675066A/zh active Pending
- 2008-04-16 EP EP08745977A patent/EP2147011A4/en not_active Ceased
- 2008-04-16 CA CA2684278A patent/CA2684278C/en not_active Expired - Fee Related
- 2008-04-16 JP JP2010504215A patent/JP5565906B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-06 US US13/413,177 patent/US8314076B2/en active Active
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