AR082312A1 - Una composicion farmaceutica de combinacion para tratar diabetes y desordenes metabolicos - Google Patents
Una composicion farmaceutica de combinacion para tratar diabetes y desordenes metabolicosInfo
- Publication number
- AR082312A1 AR082312A1 ARP110102642A ARP110102642A AR082312A1 AR 082312 A1 AR082312 A1 AR 082312A1 AR P110102642 A ARP110102642 A AR P110102642A AR P110102642 A ARP110102642 A AR P110102642A AR 082312 A1 AR082312 A1 AR 082312A1
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- metabolic disorders
- pharmaceutical combination
- combination composition
- treat diabetes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
Abstract
Una composición farmacéutica para administrar a un paciente que sufre desde diabetes hasta otras enfermedades metabólicas, la composición comprende: a) una forma activada potenciada de un anticuerpo contra un receptor de insulina humana, y b) una forma activada potenciada de un anticuerpo contra la NO-sintasa endotelial.Reivindicación 11: La composición farmacéutica de la reivindicación 1, caracterizada porque dicho receptor de insulina humana consiste en una secuencia seleccionada del grupo que consiste en SEQ ID Nº 1, SEQ ID Nº 2, SEQ ID Nº 3, SEQ ID Nº 4, SEQ ID Nº 5, SEQ ID Nº 6, SEQ ID Nº 7, SEQ ID Nº 8, SEQ ID Nº 9, SEQ ID Nº 10, SEQ ID Nº 11, SEQ ID Nº 12, SEQ ID Nº 13, SEQ ID Nº 14. Reivindicación 12: La composición farmacéutica de la reivindicación 1, caracterizada porque dicha NO-sintasa endotelial consiste en una secuencia provista en SEQ. ID Nº 15, SEQ ID Nº 16, SEQ ID Nº 17, SEQ ID Nº 18, SEQ ID Nº 19, SEQ ID Nº 20, SEQ ID Nº 21, SEQ ID Nº 22.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010130348/15A RU2531048C2 (ru) | 2010-07-21 | 2010-07-21 | Лекарственное средство для уменьшения резистентности к инсулину и лечения сахарного диабета и способ повышения эффективности лечения сахарного диабета инсулином и/или гипогликемическими препаратами |
| RU2011127051/15A RU2509572C2 (ru) | 2011-07-01 | 2011-07-01 | Лекарственное средство для уменьшения резистентности к инсулину и для лечения сахарного диабета, способ уменьшения резистентности к инсулину, способ лечения сахарного диабета и способ лечения сахарного диабета инсулином и/или гипогликемическими препаратами |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR082312A1 true AR082312A1 (es) | 2012-11-28 |
Family
ID=44899155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP110102642A AR082312A1 (es) | 2010-07-21 | 2011-07-21 | Una composicion farmaceutica de combinacion para tratar diabetes y desordenes metabolicos |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8617555B2 (es) |
| EP (2) | EP2595658A2 (es) |
| JP (2) | JP2013533268A (es) |
| KR (2) | KR20130103486A (es) |
| CN (1) | CN103118707A (es) |
| AR (1) | AR082312A1 (es) |
| AU (1) | AU2011281240B2 (es) |
| BR (1) | BR112013001299A2 (es) |
| CA (1) | CA2805961A1 (es) |
| CL (1) | CL2013000200A1 (es) |
| CZ (1) | CZ2013124A3 (es) |
| DE (1) | DE112011102396T5 (es) |
| DK (1) | DK201370089A (es) |
| EA (1) | EA029847B1 (es) |
| EE (1) | EE05761B1 (es) |
| ES (1) | ES2445846R1 (es) |
| FI (1) | FI20135152L (es) |
| FR (1) | FR2962913A1 (es) |
| GB (2) | GB2552405B (es) |
| IT (1) | ITTO20110627A1 (es) |
| LT (1) | LT5980B (es) |
| MX (1) | MX2013000804A (es) |
| MY (1) | MY160979A (es) |
| NO (1) | NO20130265A1 (es) |
| NZ (1) | NZ606964A (es) |
| PE (1) | PE20130815A1 (es) |
| SE (1) | SE1350212A1 (es) |
| SG (1) | SG187578A1 (es) |
| WO (1) | WO2012010966A2 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2181297C2 (ru) | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
| UA76638C2 (en) | 2002-08-02 | 2006-08-15 | Oleh Illich Epshtein | Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon |
| RU2309732C1 (ru) * | 2006-03-13 | 2007-11-10 | Олег Ильич Эпштейн | Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата |
| EA200802440A1 (ru) * | 2006-06-06 | 2009-06-30 | Олег Ильич ЭПШТЕЙН | Лекарственное средство для лечения ожирения, сахарного диабета и заболеваний с нарушением толерантности к глюкозе |
| GB2496337A (en) | 2010-07-15 | 2013-05-08 | Oleg Lliich Epshtein | Combination pharmaceutical composition and methods of treating diseases or conditions associated with neurodegenerative diseases |
| EP2593477A2 (en) | 2010-07-15 | 2013-05-22 | Oleg Iliich Epshtein | Pharmaceutical compositions and methods of treatment |
| EA030566B1 (ru) * | 2010-07-15 | 2018-08-31 | Олег Ильич ЭПШТЕЙН | Способ повышения терапевтической эффективности активированной-потенцированной формы антитела к эндогенной биомолекуле и фармацевтическая композиция |
| MX356678B (es) * | 2010-07-21 | 2018-06-08 | Oleg Iliich Epshtein | Composición farmacéutica y combinación y métodos para tratar las enfermedades o las condiciones asociadas con la enfermedad o condición respiratoria. |
| ITTO20110630A1 (it) * | 2010-07-21 | 2012-01-22 | Oleg Iliich Epshtein | Composizioni farmaceutiche di combinazione e metodo per trattare vertigini, cinetosi e distonia vascolare vegetativa |
| GB2496343B (en) | 2010-07-21 | 2017-11-01 | Iliich Epshtein Oleg | A method of treating attention deficit hyperactivity disorder |
| ES2510940R1 (es) * | 2010-08-06 | 2015-03-27 | Oleg Iliich Epshtein | Composición farmacéutica combinada y su uso para preparar un medicamento destinado al tratamiento y prevención de las enfermedades infecciosas |
| TWI588153B (zh) * | 2012-05-18 | 2017-06-21 | 中國醫藥大學 | 多胜肽、編碼該多胜肽之核酸分子、以及該多胜肽之應用 |
| RU2013111961A (ru) | 2013-03-18 | 2014-09-27 | Олег Ильич Эпштейн | Способ определения выраженности модифицирующей активности, ассоциированной с носителем |
| RU2013111962A (ru) | 2013-03-18 | 2014-09-27 | Олег Ильич Эпштейн | Способ определения выраженности модифицирующей активности, ассоциированной с носителем |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4311897A (en) | 1979-08-28 | 1982-01-19 | Union Carbide Corporation | Plasma arc torch and nozzle assembly |
| US5811437A (en) * | 1996-05-21 | 1998-09-22 | Eli Lilly And Company | Methods of increasing nitric oxide synthesis |
| US6150500A (en) * | 1996-07-12 | 2000-11-21 | Salerno; John C. | Activators of endothelial nitric oxide synthase |
| WO1999026657A1 (en) * | 1997-11-25 | 1999-06-03 | Musc Foundation For Research Development | Inhibitors of nitric oxide synthase |
| US6933272B1 (en) * | 1998-09-22 | 2005-08-23 | Erik Helmerhorst | Use of non-peptidyl compounds for the treatment of insulin related ailments |
| RU2181297C2 (ru) * | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
| UA76638C2 (en) | 2002-08-02 | 2006-08-15 | Oleh Illich Epshtein | Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon |
| UA76639C2 (uk) * | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Гомеопатичний лікарський засіб та спосіб лікування еректильних дисфункцій |
| UA76641C2 (uk) | 2002-08-02 | 2006-08-15 | Олєг Ільіч Епштєйн | Гомеопатичний лікарський засіб та спосіб лікування захворювань передміхурової залози |
| WO2004017913A2 (en) * | 2002-08-22 | 2004-03-04 | Nutrition 21, Inc. | Arginine silicate inositol complex and use thereof |
| TWI345470B (en) | 2003-03-14 | 2011-07-21 | Nutrition Res Inc | Homeopathic formulations useful for treating pain and/or inflammation |
| WO2005067928A1 (en) * | 2004-01-20 | 2005-07-28 | Astellas Pharma Inc. | Method for treating erectile dysfunction |
| RU2438707C2 (ru) * | 2006-06-06 | 2012-01-10 | Олег Ильич Эпштейн | Лекарственное средство для перорального лечения сахарного диабета и других заболеваний, сопровождающихся нарушением толерантности к глюкозе, и способ получения твердой лекарственной формы для пероральной терапии сахарного диабета и других заболеваний, сопровождающихся нарушением толерантности к глюкозе |
| EA200802440A1 (ru) * | 2006-06-06 | 2009-06-30 | Олег Ильич ЭПШТЕЙН | Лекарственное средство для лечения ожирения, сахарного диабета и заболеваний с нарушением толерантности к глюкозе |
| GB0812019D0 (en) * | 2008-07-02 | 2008-08-06 | Asterion Ltd | Insulin |
| GB2496337A (en) * | 2010-07-15 | 2013-05-08 | Oleg Lliich Epshtein | Combination pharmaceutical composition and methods of treating diseases or conditions associated with neurodegenerative diseases |
| EA030566B1 (ru) * | 2010-07-15 | 2018-08-31 | Олег Ильич ЭПШТЕЙН | Способ повышения терапевтической эффективности активированной-потенцированной формы антитела к эндогенной биомолекуле и фармацевтическая композиция |
| EP2593477A2 (en) * | 2010-07-15 | 2013-05-22 | Oleg Iliich Epshtein | Pharmaceutical compositions and methods of treatment |
| ITTO20110630A1 (it) * | 2010-07-21 | 2012-01-22 | Oleg Iliich Epshtein | Composizioni farmaceutiche di combinazione e metodo per trattare vertigini, cinetosi e distonia vascolare vegetativa |
| MX356678B (es) * | 2010-07-21 | 2018-06-08 | Oleg Iliich Epshtein | Composición farmacéutica y combinación y métodos para tratar las enfermedades o las condiciones asociadas con la enfermedad o condición respiratoria. |
-
2011
- 2011-07-15 BR BR112013001299A patent/BR112013001299A2/pt not_active Application Discontinuation
- 2011-07-15 JP JP2013520235A patent/JP2013533268A/ja active Pending
- 2011-07-15 EA EA201300124A patent/EA029847B1/ru not_active IP Right Cessation
- 2011-07-15 MY MYPI2013000225A patent/MY160979A/en unknown
- 2011-07-15 GB GB1707872.6A patent/GB2552405B/en not_active Expired - Fee Related
- 2011-07-15 KR KR1020137004330A patent/KR20130103486A/ko active Application Filing
- 2011-07-15 US US13/135,891 patent/US8617555B2/en active Active
- 2011-07-15 PE PE2013000114A patent/PE20130815A1/es not_active Application Discontinuation
- 2011-07-15 EP EP11773314.7A patent/EP2595658A2/en not_active Ceased
- 2011-07-15 CN CN2011800454899A patent/CN103118707A/zh active Pending
- 2011-07-15 SE SE1350212A patent/SE1350212A1/sv unknown
- 2011-07-15 FR FR1156480A patent/FR2962913A1/fr not_active Withdrawn
- 2011-07-15 AU AU2011281240A patent/AU2011281240B2/en not_active Ceased
- 2011-07-15 KR KR1020187032943A patent/KR20180127515A/ko not_active Application Discontinuation
- 2011-07-15 EE EEP201300007A patent/EE05761B1/et not_active IP Right Cessation
- 2011-07-15 CZ CZ20130124A patent/CZ2013124A3/cs unknown
- 2011-07-15 DE DE112011102396T patent/DE112011102396T5/de not_active Withdrawn
- 2011-07-15 CA CA2805961A patent/CA2805961A1/en not_active Abandoned
- 2011-07-15 WO PCT/IB2011/002177 patent/WO2012010966A2/en active Application Filing
- 2011-07-15 GB GB1302924.4A patent/GB2496799B/en not_active Expired - Fee Related
- 2011-07-15 NZ NZ606964A patent/NZ606964A/en not_active IP Right Cessation
- 2011-07-15 IT IT000627A patent/ITTO20110627A1/it unknown
- 2011-07-15 MX MX2013000804A patent/MX2013000804A/es active IP Right Grant
- 2011-07-15 ES ES201390009A patent/ES2445846R1/es active Pending
- 2011-07-15 EP EP19213849.3A patent/EP3693018A1/en not_active Withdrawn
- 2011-07-15 SG SG2013004817A patent/SG187578A1/en unknown
- 2011-07-21 AR ARP110102642A patent/AR082312A1/es not_active Application Discontinuation
-
2013
- 2013-01-21 CL CL2013000200A patent/CL2013000200A1/es unknown
- 2013-02-18 NO NO20130265A patent/NO20130265A1/no not_active Application Discontinuation
- 2013-02-19 LT LT2013018A patent/LT5980B/lt not_active IP Right Cessation
- 2013-02-19 DK DKPA201370089A patent/DK201370089A/da not_active Application Discontinuation
- 2013-02-21 FI FI20135152A patent/FI20135152L/fi not_active Application Discontinuation
-
2016
- 2016-07-01 JP JP2016131729A patent/JP2016222684A/ja active Pending
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