JP2017524348A5 - - Google Patents

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Publication number
JP2017524348A5
JP2017524348A5 JP2016572566A JP2016572566A JP2017524348A5 JP 2017524348 A5 JP2017524348 A5 JP 2017524348A5 JP 2016572566 A JP2016572566 A JP 2016572566A JP 2016572566 A JP2016572566 A JP 2016572566A JP 2017524348 A5 JP2017524348 A5 JP 2017524348A5
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JP
Japan
Prior art keywords
ptpn2
leukocytes
cell
inhibitor
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016572566A
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English (en)
Japanese (ja)
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JP2017524348A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/AU2015/050318 external-priority patent/WO2015188228A1/en
Publication of JP2017524348A publication Critical patent/JP2017524348A/ja
Publication of JP2017524348A5 publication Critical patent/JP2017524348A5/ja
Pending legal-status Critical Current

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JP2016572566A 2014-06-10 2015-06-10 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法 Pending JP2017524348A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2014902203 2014-06-10
AU2014902203A AU2014902203A0 (en) 2014-06-10 Method of producing cells for adoptive cell transfer
AU2015901171 2015-03-31
AU2015901171A AU2015901171A0 (en) 2015-03-31 Method of producing cells for adoptive cell transfer (2)
PCT/AU2015/050318 WO2015188228A1 (en) 2014-06-10 2015-06-10 Method of producing leukocytes using ptpn2 inhibition for adoptive cell transfer

Publications (2)

Publication Number Publication Date
JP2017524348A JP2017524348A (ja) 2017-08-31
JP2017524348A5 true JP2017524348A5 (enExample) 2018-06-07

Family

ID=54832624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016572566A Pending JP2017524348A (ja) 2014-06-10 2015-06-10 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法

Country Status (5)

Country Link
US (2) US20170224731A1 (enExample)
EP (1) EP3154555A4 (enExample)
JP (1) JP2017524348A (enExample)
AU (1) AU2015274242A1 (enExample)
WO (1) WO2015188228A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL295616A (en) 2015-07-31 2022-10-01 Us Health Adapted cells and treatment methods
EP4338799A3 (en) 2016-10-18 2024-06-05 Regents of the University of Minnesota Tumor infiltrating lymphocytes and methods of therapy
WO2018148378A1 (en) * 2017-02-08 2018-08-16 Dana-Farber Cancer Institute, Inc. Modulating biomarkers to increase tumor immunity and improve the efficiacy of cancer immunotherapy
EP3645021A4 (en) 2017-06-30 2021-04-21 Intima Bioscience, Inc. ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
WO2019036815A1 (en) * 2017-08-24 2019-02-28 The Royal Institution For The Advancement Of Learning/Mcgill University ENHANCEMENT OF CD8 + T LYMPHOCYTES FOR ADOPTIVE CELL THERAPY BY INHIBITING PTPN1 (PTP1B) AND PTPN2 (TC-PTP))
JP2021518160A (ja) 2018-03-15 2021-08-02 ケーエスキュー セラピューティクス， インコーポレイテッド 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法
AU2019236204B2 (en) 2018-03-15 2026-02-26 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
EP3765608A4 (en) * 2018-03-15 2022-01-12 KSQ Therapeutics, Inc. GENE REGULATORY COMPOSITIONS AND METHODS FOR IMPROVED IMMUNOTHERAPY
US20210207095A1 (en) * 2018-06-01 2021-07-08 Monash University Methods of activating cells via ptp 1b inhibition
CA3104507A1 (en) 2018-06-21 2019-12-26 Calico Life Sciences Llc Protein tyrosine phosphatase inhibitors and methods of use thereof
WO2020072126A2 (en) * 2018-08-07 2020-04-09 Dana-Farber Cancer Institute, Inc. Modulating ptpn2 to increase immune responses and perturbing gene expression in hematopoietic stem cell lineages
WO2020163365A2 (en) * 2019-02-04 2020-08-13 KSQ Therapeutics, Inc. Combination gene targets for improved immunotherapy
MX2021010544A (es) 2019-03-14 2021-10-01 Calico Life Sciences Llc Inhibidores de la proteina tirosina fosfatasa y metodos para usarlos.
US12188045B2 (en) 2019-06-07 2025-01-07 KSQ Therapeutics, Inc. Guide RNA combinations and methods of use
KR20220119038A (ko) * 2019-11-25 2022-08-26 케이에스큐 세러퓨틱스 인코포레이티드 종양 침윤 림프구의 활성화 및 확장을 위한 방법
AU2020395612A1 (en) * 2019-12-04 2022-06-09 Monash University Methods of activating cytotoxic leukocytes using PTP1B and PTPN2 inhibitors
CA3163012A1 (en) * 2019-12-12 2021-06-17 Yi Liu Compositions and methods for potentiating immune activity
CN113827727B (zh) * 2020-06-24 2025-04-29 上海交通大学医学院附属瑞金医院 Ptpn2抑制剂在kras突变肿瘤中的应用
KR20240099259A (ko) 2021-10-14 2024-06-28 아스널 바이오사이언시스, 인크. 공동 발현된 shrna 및 논리 게이트 시스템을 갖는 면역 세포
JP2026507228A (ja) 2023-03-03 2026-02-27 アーセナル バイオサイエンシズ インコーポレイテッド Ｐｓｍａ及びｃａ９を標的とするシステム
TW202500126A (zh) 2023-05-24 2025-01-01 美商金橘生物科技公司 雜環化合物及其用途
WO2025075947A1 (en) * 2023-10-06 2025-04-10 Purdue Research Foundation Selective tc-ptp degraders for cancer immunotherapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008043181A1 (en) * 2006-10-12 2008-04-17 Mcgill University Augmenting stem cell populations by modulating t-cell protein tyrosine phosphatase (tc-ptp)
WO2010118241A2 (en) * 2009-04-08 2010-10-14 Indiana University Research & Technology Corporation Inhibitors of protein tyrosine phosphatases
US9937205B2 (en) * 2012-09-04 2018-04-10 The Trustees Of The University Of Pennsylvania Inhibition of diacylglycerol kinase to augment adoptive T cell transfer
AR092745A1 (es) * 2012-10-01 2015-04-29 Univ Pennsylvania Composiciones que comprenden un dominio de union anti-fap y metodos para hacer blanco en celulas estromales para el tratamiento del cancer
WO2014066137A1 (en) * 2012-10-22 2014-05-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for enhancing cancer immunotherapy
RU2725542C2 (ru) * 2013-05-13 2020-07-02 Селлектис Способы конструирования высокоактивных т-клеток для иммунотерапии
CN105431524B (zh) * 2013-06-10 2020-04-21 达娜-法勃肿瘤研究所公司 用于降低肿瘤细胞的免疫抑制的方法和组合物
WO2015127548A1 (en) * 2014-02-28 2015-09-03 The Royal Institution For The Advancement Of Learning / Mcgill University Tc-ptp inhibitors as apc activators for immunotherapy
WO2015136001A1 (en) * 2014-03-11 2015-09-17 Cellectis Method for generating t-cells compatible for allogenic transplantation

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