JP2017524348A - 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法 - Google Patents

養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法 Download PDF

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JP2017524348A
JP2017524348A JP2016572566A JP2016572566A JP2017524348A JP 2017524348 A JP2017524348 A JP 2017524348A JP 2016572566 A JP2016572566 A JP 2016572566A JP 2016572566 A JP2016572566 A JP 2016572566A JP 2017524348 A JP2017524348 A JP 2017524348A
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cells
ptpn2
cancer
cell
leukocytes
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JP2017524348A5 (enExample
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トニー ティガニス，
トニー ティガニス，
フロリアン ウィーデ，
フロリアン ウィーデ，
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Monash University
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Monash University
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JP2016572566A 2014-06-10 2015-06-10 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法 Pending JP2017524348A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2014902203 2014-06-10
AU2014902203A AU2014902203A0 (en) 2014-06-10 Method of producing cells for adoptive cell transfer
AU2015901171A AU2015901171A0 (en) 2015-03-31 Method of producing cells for adoptive cell transfer (2)
AU2015901171 2015-03-31
PCT/AU2015/050318 WO2015188228A1 (en) 2014-06-10 2015-06-10 Method of producing leukocytes using ptpn2 inhibition for adoptive cell transfer

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JP2017524348A true JP2017524348A (ja) 2017-08-31
JP2017524348A5 JP2017524348A5 (enExample) 2018-06-07

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US (2) US20170224731A1 (enExample)
EP (1) EP3154555A4 (enExample)
JP (1) JP2017524348A (enExample)
AU (1) AU2015274242A1 (enExample)
WO (1) WO2015188228A1 (enExample)

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JP2021518162A (ja) * 2018-03-15 2021-08-02 ケーエスキュー セラピューティクス， インコーポレイテッド 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法
JP2022519595A (ja) * 2019-02-04 2022-03-24 ケーエスキュー セラピューティクス， インコーポレイテッド 免疫療法の改善のための遺伝子標的の組み合わせ
JP2023502780A (ja) * 2019-11-25 2023-01-25 ケーエスキュー セラピューティクス， インコーポレイテッド 腫瘍浸潤リンパ球の活性化及び増殖方法
JP2023506227A (ja) * 2019-12-12 2023-02-15 カムクワット バイオサイエンシーズ インコーポレイテッド 免疫活性を強化するための組成物および方法
US12123021B2 (en) 2018-03-15 2024-10-22 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy

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WO2017023801A1 (en) 2015-07-31 2017-02-09 Regents Of The University Of Minnesota Intracellular genomic transplant and methods of therapy
EP4338799A3 (en) 2016-10-18 2024-06-05 Regents of the University of Minnesota Tumor infiltrating lymphocytes and methods of therapy
WO2018148378A1 (en) * 2017-02-08 2018-08-16 Dana-Farber Cancer Institute, Inc. Modulating biomarkers to increase tumor immunity and improve the efficiacy of cancer immunotherapy
EP3645021A4 (en) 2017-06-30 2021-04-21 Intima Bioscience, Inc. ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
CA3073755A1 (en) 2017-08-24 2019-02-28 The Royal Institution For The Advancement Of Learning/Mcgill Universit Enhancing cd8+ t cells for adoptive cell therapy by inhibiting ptpn1 (ptp1b) and ptpn2 (tc-ptp)
BR112020018658A2 (pt) 2018-03-15 2020-12-29 KSQ Therapeutics, Inc. Composições de regulação gênica e métodos para imu-noterapia aprimorada
US20210207095A1 (en) * 2018-06-01 2021-07-08 Monash University Methods of activating cells via ptp 1b inhibition
BR112020026086A2 (pt) 2018-06-21 2021-03-23 Calico Life Sciences Llc inibidores da proteína tirosina fosfatase e métodos de uso destes
WO2020072126A2 (en) * 2018-08-07 2020-04-09 Dana-Farber Cancer Institute, Inc. Modulating ptpn2 to increase immune responses and perturbing gene expression in hematopoietic stem cell lineages
TWI849082B (zh) 2019-03-14 2024-07-21 美商嘉來克生命科學有限責任公司 蛋白酪胺酸磷酸酶抑制劑及其使用方法
US12188045B2 (en) 2019-06-07 2025-01-07 KSQ Therapeutics, Inc. Guide RNA combinations and methods of use
CN115003315A (zh) * 2019-12-04 2022-09-02 莫纳什大学 使用ptp1b和ptpn2抑制剂激活细胞毒性白细胞的方法
CN113827727B (zh) * 2020-06-24 2025-04-29 上海交通大学医学院附属瑞金医院 Ptpn2抑制剂在kras突变肿瘤中的应用
CR20240195A (es) 2021-10-14 2024-06-20 Arsenal Biosciences Inc Células inmunitarias que tienen arnhc coexpresados y sistemas de compuerta lógica
AU2024233625A1 (en) 2023-03-03 2025-09-18 Arsenal Biosciences, Inc. Systems targeting psma and ca9
WO2025075947A1 (en) * 2023-10-06 2025-04-10 Purdue Research Foundation Selective tc-ptp degraders for cancer immunotherapy

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021518162A (ja) * 2018-03-15 2021-08-02 ケーエスキュー セラピューティクス， インコーポレイテッド 免疫療法の改善のための遺伝子調節組成物及び遺伝子調節方法
US12123021B2 (en) 2018-03-15 2024-10-22 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
US12280111B2 (en) 2018-03-15 2025-04-22 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
JP2022519595A (ja) * 2019-02-04 2022-03-24 ケーエスキュー セラピューティクス， インコーポレイテッド 免疫療法の改善のための遺伝子標的の組み合わせ
JP2023502780A (ja) * 2019-11-25 2023-01-25 ケーエスキュー セラピューティクス， インコーポレイテッド 腫瘍浸潤リンパ球の活性化及び増殖方法
JP2023506227A (ja) * 2019-12-12 2023-02-15 カムクワット バイオサイエンシーズ インコーポレイテッド 免疫活性を強化するための組成物および方法

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