JP2010522700A5 - - Google Patents
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- Publication number
- JP2010522700A5 JP2010522700A5 JP2010500048A JP2010500048A JP2010522700A5 JP 2010522700 A5 JP2010522700 A5 JP 2010522700A5 JP 2010500048 A JP2010500048 A JP 2010500048A JP 2010500048 A JP2010500048 A JP 2010500048A JP 2010522700 A5 JP2010522700 A5 JP 2010522700A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- methyl
- methylspiro
- cyclopropyl
- heptane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 2,2,6-trimethylcyclohexyl Chemical group 0.000 claims 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 6
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 6
- 230000000903 blocking effect Effects 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 3
- VTCRWXGVGZLALO-UHFFFAOYSA-N 1-methyl-2-[(1,2,2-trimethyl-3-bicyclo[3.1.0]hexanyl)methyl]cyclopropane-1-carboxylic acid Chemical compound OC(=O)C1(C)CC1CC1C(C)(C)C2(C)CC2C1 VTCRWXGVGZLALO-UHFFFAOYSA-N 0.000 claims 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- RERQSUBOVZBXHE-VOTSOKGWSA-N (e)-3-[1-(2,2,3-trimethylcyclopent-3-en-1-yl)cyclopropyl]prop-2-enoic acid Chemical compound CC1(C)C(C)=CCC1C1(\C=C\C(O)=O)CC1 RERQSUBOVZBXHE-VOTSOKGWSA-N 0.000 claims 1
- VCCJRCPLNWXPON-NSCUHMNNSA-N (e)-4-(1-methyl-2-bicyclo[3.1.0]hexanyl)but-3-enoic acid Chemical compound C1CC(\C=C\CC(O)=O)C2(C)C1C2 VCCJRCPLNWXPON-NSCUHMNNSA-N 0.000 claims 1
- JDSGMYDTHXDPSJ-GQCTYLIASA-N (e)-4-(2,2,3-trimethylcyclopentyl)but-2-enoic acid Chemical compound CC1CCC(C\C=C\C(O)=O)C1(C)C JDSGMYDTHXDPSJ-GQCTYLIASA-N 0.000 claims 1
- UBOAGQFOYPWMRQ-SNAWJCMRSA-N (e)-4-(2,2,3-trimethylcyclopentyl)but-3-enoic acid Chemical compound CC1CCC(\C=C\CC(O)=O)C1(C)C UBOAGQFOYPWMRQ-SNAWJCMRSA-N 0.000 claims 1
- FSYYIWKNWSLCDN-DUXPYHPUSA-N (e)-4-(4-methylspiro[2.4]heptan-7-yl)but-2-enoic acid Chemical compound CC1CCC(C\C=C\C(O)=O)C11CC1 FSYYIWKNWSLCDN-DUXPYHPUSA-N 0.000 claims 1
- RNTNQSXSWNVYGY-NSCUHMNNSA-N (e)-4-(4-methylspiro[2.4]heptan-7-yl)but-3-enoic acid Chemical compound CC1CCC(\C=C\CC(O)=O)C11CC1 RNTNQSXSWNVYGY-NSCUHMNNSA-N 0.000 claims 1
- SPCQQNDKLJFBNA-DUXPYHPUSA-N (e)-4-(7-methylspiro[2.4]hept-6-en-4-yl)but-2-enoic acid Chemical compound CC1=CCC(C\C=C\C(O)=O)C11CC1 SPCQQNDKLJFBNA-DUXPYHPUSA-N 0.000 claims 1
- DXSRHFVZAUTTBE-XVNBXDOJSA-N (e)-4-(8-methylspiro[2.5]oct-7-en-4-yl)but-2-enoic acid Chemical compound CC1=CCCC(C\C=C\C(O)=O)C11CC1 DXSRHFVZAUTTBE-XVNBXDOJSA-N 0.000 claims 1
- HZLWXBYPIARCGW-SNAWJCMRSA-N 1-[(e)-2-(1-methyl-2-bicyclo[3.1.0]hexanyl)ethenyl]cyclopropane-1-carboxylic acid Chemical compound CC12CC1CCC2\C=C\C1(C(O)=O)CC1 HZLWXBYPIARCGW-SNAWJCMRSA-N 0.000 claims 1
- JKSQXNOUOSUVNZ-SNAWJCMRSA-N 1-[(e)-2-(4-methylspiro[2.4]heptan-7-yl)ethenyl]cyclopropane-1-carboxylic acid Chemical compound C1CC11C(C)CCC1\C=C\C1(C(O)=O)CC1 JKSQXNOUOSUVNZ-SNAWJCMRSA-N 0.000 claims 1
- MMEKRTLZYPFBNP-UHFFFAOYSA-N 1-[2-(4-methylspiro[2.4]heptan-7-yl)ethyl]cyclopropane-1-carboxylic acid Chemical compound C1CC11C(C)CCC1CCC1(C(O)=O)CC1 MMEKRTLZYPFBNP-UHFFFAOYSA-N 0.000 claims 1
- VQBSGHGICMYQGM-UHFFFAOYSA-N 2,2-dimethyl-4-(2,2,3-trimethylcyclopentyl)butanoic acid Chemical compound CC1CCC(CCC(C)(C)C(O)=O)C1(C)C VQBSGHGICMYQGM-UHFFFAOYSA-N 0.000 claims 1
- NDLNYVBNKQVKIM-UHFFFAOYSA-N 2-(3,4-dimethylcyclohexyl)acetic acid Chemical compound CC1CCC(CC(O)=O)CC1C NDLNYVBNKQVKIM-UHFFFAOYSA-N 0.000 claims 1
- MLHVLSFCLWASNP-UHFFFAOYSA-N 2-[(1,4-dimethyl-2-bicyclo[3.1.0]hexanyl)methyl]-1-methylcyclopropane-1-carboxylic acid Chemical compound CC12CC1C(C)CC2CC1CC1(C)C(O)=O MLHVLSFCLWASNP-UHFFFAOYSA-N 0.000 claims 1
- DNSDREPILBQXKN-UHFFFAOYSA-N 2-[(4,5-dimethylspiro[2.4]heptan-7-yl)methyl]-1-methylcyclopropane-1-carboxylic acid Chemical compound C1CC21C(C)C(C)CC2CC1CC1(C)C(O)=O DNSDREPILBQXKN-UHFFFAOYSA-N 0.000 claims 1
- VRFZBVPLWNHCKL-UHFFFAOYSA-N 2-[1-[(1,4-dimethyl-2-bicyclo[3.1.0]hexanyl)methyl]cyclopropyl]propanoic acid Chemical compound C1C(C)C2CC2(C)C1CC1(C(C(O)=O)C)CC1 VRFZBVPLWNHCKL-UHFFFAOYSA-N 0.000 claims 1
- RZFCTOIYOWTBPT-UHFFFAOYSA-N 2-[1-[(1-methyl-2-bicyclo[3.1.0]hexanyl)methyl]cyclopropyl]acetic acid Chemical compound CC12CC1CCC2CC1(CC(O)=O)CC1 RZFCTOIYOWTBPT-UHFFFAOYSA-N 0.000 claims 1
- CXYZORLHNHLYAH-UHFFFAOYSA-N 3,3-dimethyl-4-(2,2,3-trimethylcyclopentyl)butanoic acid Chemical compound CC1CCC(CC(C)(C)CC(O)=O)C1(C)C CXYZORLHNHLYAH-UHFFFAOYSA-N 0.000 claims 1
- QTALZWUULKHVTK-UHFFFAOYSA-N 3-(2,2,6-trimethylcyclohexyl)propanoic acid Chemical compound CC1CCCC(C)(C)C1CCC(O)=O QTALZWUULKHVTK-UHFFFAOYSA-N 0.000 claims 1
- IZZFEHBOGAIUMT-UHFFFAOYSA-N 4-(1-methyl-2-bicyclo[3.1.0]hexanyl)butanoic acid Chemical compound C1CC(CCCC(O)=O)C2(C)C1C2 IZZFEHBOGAIUMT-UHFFFAOYSA-N 0.000 claims 1
- YRIPPWABYROTJJ-UHFFFAOYSA-N 4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-enoic acid Chemical compound CC1=CCC(CC=CC(O)=O)C1(C)C YRIPPWABYROTJJ-UHFFFAOYSA-N 0.000 claims 1
- LYFXCRCUENNESS-UHFFFAOYSA-N 4-(2,2,3-trimethylcyclopentyl)butanoic acid Chemical compound CC1CCC(CCCC(O)=O)C1(C)C LYFXCRCUENNESS-UHFFFAOYSA-N 0.000 claims 1
- 239000001274 FEMA 4529 Substances 0.000 claims 1
- LDHQCZJRKDOVOX-NSCUHMNNSA-N crotonic acid Chemical compound C\C=C\C(O)=O LDHQCZJRKDOVOX-NSCUHMNNSA-N 0.000 claims 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 claims 1
- 239000002304 perfume Substances 0.000 claims 1
- 235000019260 propionic acid Nutrition 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90914307P | 2007-03-30 | 2007-03-30 | |
| US60/909,143 | 2007-03-30 | ||
| US96251507P | 2007-07-30 | 2007-07-30 | |
| US60/962,515 | 2007-07-30 | ||
| PCT/CH2008/000135 WO2008119196A1 (en) | 2007-03-30 | 2008-03-27 | Off-note blocking sensory organic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010522700A JP2010522700A (ja) | 2010-07-08 |
| JP2010522700A5 true JP2010522700A5 (OSRAM) | 2011-05-12 |
| JP5442595B2 JP5442595B2 (ja) | 2014-03-12 |
Family
ID=39580609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010500048A Active JP5442595B2 (ja) | 2007-03-30 | 2008-03-27 | オフノ−トを遮断する官能有機化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8409649B2 (OSRAM) |
| EP (1) | EP2139841B1 (OSRAM) |
| JP (1) | JP5442595B2 (OSRAM) |
| AT (1) | ATE555670T1 (OSRAM) |
| BR (1) | BRPI0809856B1 (OSRAM) |
| WO (1) | WO2008119196A1 (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2300830B1 (en) | 2008-06-13 | 2015-05-20 | Givaudan SA | Methods of identifying modulators of the bitter taste receptor tas2r44 |
| EP2329263A1 (en) * | 2008-08-07 | 2011-06-08 | Givaudan SA | Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor tas2r46 |
| US8329239B2 (en) * | 2009-03-03 | 2012-12-11 | Givandan S.A. | Off-taste masking |
| KR20130055595A (ko) | 2010-04-15 | 2013-05-28 | 크로모셀 코포레이션 | 쓴맛을 감소시키거나 제거하기 위한 화합물, 조성물 및 방법 |
| US20140005153A1 (en) * | 2011-03-14 | 2014-01-02 | Givaudan S. A. | Off-Note Masking |
| JP5883599B2 (ja) * | 2011-09-20 | 2016-03-15 | 花王株式会社 | カテキン類の苦味抑制剤の評価又は選択方法 |
| BR112014009047A2 (pt) | 2011-10-20 | 2017-04-18 | Chromocell Corp | compostos, composições e métodos para reduzir ou eliminar o sabor amargo |
| CN103998933B (zh) | 2011-10-20 | 2016-12-14 | 卓莫赛尔公司 | 鉴定调节苦味的化合物的测定 |
| WO2013072332A1 (en) | 2011-11-14 | 2013-05-23 | Givaudan Sa | Methods of using antagonists of bitter taste receptors |
| US10798961B2 (en) * | 2013-03-15 | 2020-10-13 | Altria Client Services Llc | Functional food and beverage compositions with improved taste through the use of sensates |
| WO2014150967A1 (en) | 2013-03-15 | 2014-09-25 | Altria Client Services Inc. | Oral energy products including encapsulated caffeine |
| CN105358983B (zh) | 2013-04-24 | 2018-08-03 | 卓莫赛尔公司 | 用于鉴定调节苦味的化合物的测定 |
| EP3135663B1 (en) * | 2014-04-21 | 2019-02-27 | Takasago International Corporation | Novel compound, and flavor composition containing said compound |
| CN105801636A (zh) * | 2016-03-24 | 2016-07-27 | 济南诚汇双达化工有限公司 | 一种柚皮苷二氢查尔酮的合成方法 |
| US20220104524A1 (en) * | 2017-06-02 | 2022-04-07 | Givaudan, S.A. | Compositions |
| US12274283B2 (en) | 2018-09-20 | 2025-04-15 | The Better Meat Co. | Enhanced aerobic fermentation methods for producing edible fungal mycelium blended meats and meat analogue compositions |
| CN113056202A (zh) | 2018-09-20 | 2021-06-29 | 贝特尔肉制品公司 | 用于生产可食用的真菌菌丝体共混肉和肉类似物组合物的增强的好氧发酵方法 |
| CN109588688A (zh) * | 2019-01-22 | 2019-04-09 | 中国计量大学 | 一种采用山梨酸钾控制酱油中生物胺含量的方法 |
| PL240449B1 (pl) * | 2019-05-06 | 2022-04-04 | Univ Medyczny Im Piastow Slaskich We Wroclawiu | Pochodna terpenoidowa do zastosowania w chemoprewencji i wspomaganiu chemioterapii nowotworów |
| CA3179775A1 (en) | 2020-04-20 | 2021-10-28 | Givaudan Sa | Compositions |
| GB202007984D0 (en) | 2020-05-28 | 2020-07-15 | Givaudan Sa | Compositions |
| US20240292868A1 (en) * | 2021-06-18 | 2024-09-05 | Cargill, Incorporated | Sensory modifiers for protein compositions |
| WO2024240572A1 (en) | 2023-05-22 | 2024-11-28 | Givaudan Sa | Dried cocoa pulp composition, consumables and methods |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58500250A (ja) * | 1981-03-13 | 1983-02-17 | エル．ジ−ボ−ダン エ コンパニ− ソシエテ アノニム | 香料組成物 |
| EP0073984B1 (de) * | 1981-09-09 | 1988-04-27 | L. GIVAUDAN & CIE Société Anonyme | Riech- und/oder Geschmackstoffkompositionen mit einem Gehalt an ungesättigten Säuren |
| JPS60109537A (ja) * | 1983-11-18 | 1985-06-15 | T Hasegawa Co Ltd | シクロペンテン誘導体 |
| US20020004092A1 (en) * | 2000-02-02 | 2002-01-10 | Riha William E. | Low calorie beverages containing high intensity sweeteners and arabinogalactan |
| US20030035875A1 (en) * | 2001-04-03 | 2003-02-20 | Dulebohn Joel I. | Composition for improving the taste and sweetness profile of beverages having intense sweeteners |
| EP2267128A3 (en) | 2002-09-25 | 2011-08-10 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Bitter taste receptors |
| US7632531B2 (en) * | 2003-04-11 | 2009-12-15 | International Flavors & Fragnances Inc. | Alkyldienamides exhibiting taste and sensory effect in flavor compositions |
| US20060024335A1 (en) * | 2004-07-29 | 2006-02-02 | Roger Stier E | Oral compositions which mask the bitter taste of a bitter-tasting agent |
| US8367137B2 (en) * | 2005-11-23 | 2013-02-05 | The Coca-Cola Company | High-potency sweetener composition with fatty acid and compositions sweetened therewith |
-
2008
- 2008-03-27 JP JP2010500048A patent/JP5442595B2/ja active Active
- 2008-03-27 AT AT08714785T patent/ATE555670T1/de active
- 2008-03-27 WO PCT/CH2008/000135 patent/WO2008119196A1/en not_active Ceased
- 2008-03-27 US US12/593,114 patent/US8409649B2/en active Active
- 2008-03-27 EP EP08714785A patent/EP2139841B1/en active Active
- 2008-03-27 BR BRPI0809856A patent/BRPI0809856B1/pt active IP Right Grant
-
2013
- 2013-03-29 US US13/853,575 patent/US9451784B2/en active Active
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