JP2010521495A - 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 - Google Patents

漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 Download PDF

Info

Publication number
JP2010521495A
JP2010521495A JP2009553828A JP2009553828A JP2010521495A JP 2010521495 A JP2010521495 A JP 2010521495A JP 2009553828 A JP2009553828 A JP 2009553828A JP 2009553828 A JP2009553828 A JP 2009553828A JP 2010521495 A JP2010521495 A JP 2010521495A
Authority
JP
Japan
Prior art keywords
self
xaa
formulation
peptide
assembling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009553828A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010521495A5 (cg-RX-API-DMAC7.html
Inventor
ラトリッジ エリス−ベーンク，
スティーブン リチャード ケリー，
テレンス ダブリュー． ノーチ，
Original Assignee
アーチ セラピューティクス， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アーチ セラピューティクス， インコーポレイテッド filed Critical アーチ セラピューティクス， インコーポレイテッド
Publication of JP2010521495A publication Critical patent/JP2010521495A/ja
Publication of JP2010521495A5 publication Critical patent/JP2010521495A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
JP2009553828A 2007-03-14 2008-03-14 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 Withdrawn JP2010521495A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89487207P 2007-03-14 2007-03-14
PCT/US2008/057104 WO2008113030A2 (en) 2007-03-14 2008-03-14 Treatment of leaky or damaged tight junctions and enhancing extracellular matrix

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013133118A Division JP5860437B2 (ja) 2007-03-14 2013-06-25 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強

Publications (2)

Publication Number Publication Date
JP2010521495A true JP2010521495A (ja) 2010-06-24
JP2010521495A5 JP2010521495A5 (cg-RX-API-DMAC7.html) 2011-04-28

Family

ID=39462068

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2009553828A Withdrawn JP2010521495A (ja) 2007-03-14 2008-03-14 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2013133118A Expired - Fee Related JP5860437B2 (ja) 2007-03-14 2013-06-25 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2014227726A Expired - Fee Related JP6112621B2 (ja) 2007-03-14 2014-11-10 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2017043479A Pending JP2017105833A (ja) 2007-03-14 2017-03-08 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2013133118A Expired - Fee Related JP5860437B2 (ja) 2007-03-14 2013-06-25 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2014227726A Expired - Fee Related JP6112621B2 (ja) 2007-03-14 2014-11-10 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP2017043479A Pending JP2017105833A (ja) 2007-03-14 2017-03-08 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強

Country Status (7)

Country Link
US (2) US9415084B2 (cg-RX-API-DMAC7.html)
EP (1) EP2146733B1 (cg-RX-API-DMAC7.html)
JP (4) JP2010521495A (cg-RX-API-DMAC7.html)
CA (1) CA2680824C (cg-RX-API-DMAC7.html)
DK (1) DK2146733T3 (cg-RX-API-DMAC7.html)
ES (1) ES2854674T3 (cg-RX-API-DMAC7.html)
WO (1) WO2008113030A2 (cg-RX-API-DMAC7.html)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014162906A1 (ja) * 2013-03-30 2014-10-09 株式会社糖鎖工学研究所 糖鎖－ポリペプチド複合体
WO2015053338A1 (ja) * 2013-10-08 2015-04-16 学校法人東京理科大学 カチオン性ペプチドおよびそれを含む医薬組成物
WO2015145797A1 (ja) * 2014-03-28 2015-10-01 大塚化学株式会社 止血用医薬組成物
JP2016528018A (ja) * 2013-08-22 2016-09-15 アーチ・バイオサージェリー・インコーポレイテッド 流体の移動を制御するための移植可能なメッシュ
WO2017104723A1 (ja) * 2015-12-18 2017-06-22 株式会社スリー・ディー・マトリックス 止血用組成物、および、止血用組成物を用いた止血方法
WO2024128081A1 (ja) * 2022-12-16 2024-06-20 東亞合成株式会社 合成ペプチド及び構築物

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9162005B2 (en) 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
WO2006116524A1 (en) 2005-04-25 2006-11-02 Massachusetts Institute Of Technology Compositions and methods for promoting hemostasis and other physiological activities
WO2007082304A2 (en) 2006-01-12 2007-07-19 Massachusetts Institute Of Technology Biodegradable elastomers
CA2638823A1 (en) 2006-02-13 2007-08-23 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
KR20110091019A (ko) 2006-04-25 2011-08-10 메사추세츠 인스티튜트 오브 테크놀로지 오염물, 체액 또는 다른 실재물의 이동 및/또는 다른 생리학적 상태에 영향을 주기 위한 조성물 및 방법
WO2009040087A2 (en) * 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Therapeutic use of peptide yglf and combination with kvlpvpq
RU2010113966A (ru) * 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение меланотропинстимулирующего фактора в качестве терапевтического средства
AU2008309993A1 (en) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Use of CNP-22, alone1 or in combination with physalemin, as a therapeutic agent
KR101670099B1 (ko) 2008-10-06 2016-10-27 가부시끼가이샤 쓰리디 매트릭스 조직 폐색제
US20110200560A1 (en) * 2009-05-26 2011-08-18 Massachusetts Institute Of Technology Non-ionic self-assembling peptides and uses thereof
US9084752B2 (en) * 2009-12-14 2015-07-21 The University Of Hong Kong Compositions and methods for controlling proliferation and differentiation of cells
WO2011072482A1 (en) 2009-12-14 2011-06-23 The University Of Hong Kong Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells
US20110143993A1 (en) * 2009-12-15 2011-06-16 The Brigham And Women's Hospital, Inc. Endothelial basement membrane targeting peptide ligands
JP5855651B2 (ja) * 2010-07-16 2016-02-09 マサチューセッツ インスティテュート オブ テクノロジー 改変を組み込んだ自己組織化ペプチドおよびその使用方法
US8741833B2 (en) * 2010-07-16 2014-06-03 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
JP5934710B2 (ja) * 2010-10-07 2016-06-15 マサチューセッツ インスティテュート オブ テクノロジー ローレンツ力直動型の無針式ジェット注射システムを用いた固形物および／または流体の供給
US8546338B2 (en) 2010-12-08 2013-10-01 Johnson & Johnson Consumer Companies, Inc. Self-assembling hydrogels based on dicephalic peptide amphiphiles
EP3263121B1 (en) * 2010-12-21 2019-02-27 Leidos, Inc. Methods and compositions for wound treatment
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
MX2015000863A (es) 2012-07-19 2016-05-05 Alethia Biotherapeutics Inc Anticuerpos anti-siglec-15.
EP2698162A1 (en) 2012-08-15 2014-02-19 Credentis AG Method for producing a composition for treating a tooth lesion
US9241891B2 (en) 2012-10-30 2016-01-26 The Procter & Gamble Company Personal care compositions comprising self-assembling peptides
EP2853256A1 (en) 2013-09-25 2015-04-01 Credentis AG Dental care product for tooth whitening
EP3049054B1 (en) 2013-09-25 2018-04-04 Credentis AG Dental care product for tooth whitening
BR112016019510A2 (pt) 2014-03-10 2017-10-24 3 D Matrix Ltd esterilização e filtração de composições de peptídeos
CN117138022A (zh) 2014-03-10 2023-12-01 三维矩阵有限责任公司 自组装肽组合物
EP3116524B1 (en) 2014-03-10 2018-11-28 3-D Matrix Ltd. Autoassembling peptides for the treatment of pulmonary bulla
US10814038B2 (en) 2016-01-06 2020-10-27 3-D Matrix, Ltd. Combination compositions
EP3248591A1 (en) 2016-05-24 2017-11-29 Credentis AG Method and product for caries treatment
EP3248590A1 (en) 2016-05-24 2017-11-29 Credentis AG Personal dental care product for caries treatment
WO2019040528A1 (en) * 2017-08-22 2019-02-28 The Board Of Trustees Of The Leland Stanford Junior University BIOMATERIALS INCORPORATED WITH ELAFINE FOR THE TREATMENT OF CHRONIC TISSUE ULCERS
CN111712230B (zh) 2017-12-15 2024-04-26 立美基股份有限公司 表面活性剂肽纳米结构及在药物递送中的用途
CN111867616A (zh) * 2018-01-11 2020-10-30 国立大学法人东京大学 Ntcp抑制剂
US20190292223A1 (en) * 2018-03-23 2019-09-26 Arch Biosurgery, Inc. Sap and peptidomimetics for treatment of eye disease
CA3094984A1 (en) 2018-03-23 2019-09-26 Arch Biosurgery, Inc. Sap and peptidomimetic compositions for reducing symptoms of inflammation
WO2020071527A1 (ja) * 2018-10-05 2020-04-09 学校法人 久留米大学 腸管における潰瘍または瘻孔の治療または予防のための医薬組成物
CA3140207C (en) 2019-06-13 2025-05-13 Hollister Incorporated REUSABLE URINARY CATHETER-TYPE PRODUCTS
EP3952929A1 (en) 2019-06-25 2022-02-16 Hollister Incorporated Reusable urinary catheter products
EP3831360A1 (en) 2019-12-04 2021-06-09 Credentis AG Personal dental care product for preventing demineralisation
CN111116717B (zh) * 2020-01-03 2021-10-29 中国科学院大学温州研究院(温州生物材料与工程研究所) 含有n-甲基-d-葡糖胺单元的糖肽水凝胶、制备方法及其应用
EP4090350A1 (en) 2020-01-13 2022-11-23 Arch Biosurgery, Inc. Self-assembling peptide gel formulation and methods of use
US11154470B1 (en) 2020-07-31 2021-10-26 vVardis AG Anti-inflammatory and senolytic dental care product with tooth whitening characteristics
JP2024506048A (ja) * 2021-02-10 2024-02-08 株式会社スリー・ディー・マトリックス 特異的な自己組織化ペプチドｒａｄａ１６を含む、炎症性腸疾患などの下部消化管疾患を治療又は予防するための医薬組成物
CN116789854B (zh) * 2023-06-08 2024-04-02 东北农业大学 兼具细菌捕获与抑菌功能的纳米抗菌肽及制备方法和应用
WO2025226888A1 (en) * 2024-04-26 2025-10-30 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Ecm-derived injectable embolic for permanent treatment of cerebral aneurysms

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800481B1 (en) * 1992-12-28 2004-10-05 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
WO2005014615A2 (en) * 2003-06-25 2005-02-17 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
US20060088510A1 (en) * 2004-10-25 2006-04-27 The Brigham And Women's Hospital, Inc. Targeted delivery of biological factors using self-assembling peptide nanofibers
WO2006073889A2 (en) * 2005-01-04 2006-07-13 The Brigham And Women's Hospital, Inc. Sustained delivery of pdgf using self-assembling peptide nanofibers
WO2006116524A1 (en) * 2005-04-25 2006-11-02 Massachusetts Institute Of Technology Compositions and methods for promoting hemostasis and other physiological activities

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098728A (en) 1976-01-02 1978-07-04 Solomon Rosenblatt Medical surgical sponge and method of making same
US4211227A (en) 1978-07-03 1980-07-08 The Kendall Company Surgical sponge material
US4272398A (en) 1978-08-17 1981-06-09 The United States Of America As Represented By The Secretary Of Agriculture Microencapsulation process
US4636208A (en) 1984-10-05 1987-01-13 Ewald Rath Surgical sponge
US4829000A (en) 1985-08-30 1989-05-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Reconstituted basement membrane complex with biological activity
US4861627A (en) 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
US5019646A (en) 1987-08-25 1991-05-28 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5843156A (en) 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
WO1993007813A1 (en) 1989-12-04 1993-04-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US5180375A (en) 1991-05-02 1993-01-19 Feibus Miriam H Woven surgical drain and woven surgical sponge
US5222974A (en) 1991-11-08 1993-06-29 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5670483A (en) 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5645565A (en) 1995-06-13 1997-07-08 Ethicon Endo-Surgery, Inc. Surgical plug
US6368877B1 (en) 1997-06-25 2002-04-09 Massachusetts Institute Of Technology Self-assembling peptide surfaces for cell patterning and interactions
US6235340B1 (en) 1998-04-10 2001-05-22 Massachusetts Institute Of Technology Biopolymer-resistant coatings
WO2000041732A1 (en) 1999-01-19 2000-07-20 The Children's Hospital Of Philadelphia Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof
WO2000063079A1 (en) 1999-04-15 2000-10-26 Ultracell Medical Technologies Of Connecticut, Inc. Method for producing surgical sponge device and product thereof
US6844324B1 (en) 1999-11-12 2005-01-18 Massachusetts Institute Of Technology Modular peptide mediated intracellular delivery system and uses therefore
US6953656B2 (en) 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of polypeptides
US6953659B2 (en) 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of nucleic acids
US6846319B2 (en) 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
US7449180B2 (en) 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
ATE419333T1 (de) * 2001-02-06 2009-01-15 Massachusetts Inst Technology Peptidgerüstverkapselung von gewebszellen und verwendungen davon
US7179784B2 (en) 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
WO2003052117A2 (en) 2001-09-19 2003-06-26 Massachusetts Institute Of Technology Methods and products related to non-viral transfection
AU2003222167A1 (en) 2002-04-02 2003-10-20 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
AU2003249606A1 (en) 2002-05-13 2003-12-02 Massachusetts Institute Of Technology Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof
CA2387257C (en) 2002-05-23 2009-07-28 Suncor Energy Inc. Static deaeration conditioner for processing of bitumen froth
GB0216286D0 (en) 2002-07-15 2002-08-21 Univ Leeds Network
EP1542709A2 (en) 2002-08-06 2005-06-22 EPIX Pharmaceuticals, Inc. Peptide aggregates
US7713923B2 (en) * 2003-06-25 2010-05-11 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
US7846891B2 (en) 2003-10-17 2010-12-07 Massachusetts Institute Of Technology Self-assembling peptides for regeneration and repair of neural tissue
GB0413346D0 (en) 2004-06-15 2004-07-21 Theryte Ltd Treating cancer
CA2572964C (en) * 2004-07-06 2018-03-06 3D Matrix, Inc. Purified amphiphilic peptide compositions and uses thereof
US7884185B2 (en) 2004-07-28 2011-02-08 University Of Delaware Hydrogels and uses thereof
US8039258B2 (en) 2004-09-28 2011-10-18 Ethicon, Inc. Tissue-engineering scaffolds containing self-assembled-peptide hydrogels
US9162005B2 (en) 2005-04-25 2015-10-20 Arch Biosurgery, Inc. Compositions for prevention of adhesions and other barrier applications
KR20110091019A (ko) 2006-04-25 2011-08-10 메사추세츠 인스티튜트 오브 테크놀로지 오염물, 체액 또는 다른 실재물의 이동 및/또는 다른 생리학적 상태에 영향을 주기 위한 조성물 및 방법
US20070287741A1 (en) * 2006-06-13 2007-12-13 Uri Herzberg Compositions and methods for preventing or reducing postoperative ileus and gastric stasis in mammals
US20120085262A1 (en) 2010-08-26 2012-04-12 Freudenberg Forschungsdienste Kg Production of Highly Concentrated Solutions of Self-Assembling Proteins

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800481B1 (en) * 1992-12-28 2004-10-05 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
WO2005014615A2 (en) * 2003-06-25 2005-02-17 Massachusetts Institute Of Technology Self-assembling peptides incorporating modifications and methods of use thereof
US20060088510A1 (en) * 2004-10-25 2006-04-27 The Brigham And Women's Hospital, Inc. Targeted delivery of biological factors using self-assembling peptide nanofibers
WO2006073889A2 (en) * 2005-01-04 2006-07-13 The Brigham And Women's Hospital, Inc. Sustained delivery of pdgf using self-assembling peptide nanofibers
WO2006116524A1 (en) * 2005-04-25 2006-11-02 Massachusetts Institute Of Technology Compositions and methods for promoting hemostasis and other physiological activities

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6012067399; Ｃｉｒｃｕｌａｔｉｏｎ，　Ｖｏｌ．１１１　Ｎｏ．４，　ｐ．４４２-５０　（２００５） *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2014162906A1 (ja) * 2013-03-30 2017-02-16 株式会社糖鎖工学研究所 糖鎖−ポリペプチド複合体
KR102186698B1 (ko) * 2013-03-30 2020-12-07 가부시키가이샤 도우사 고가쿠 겐큐쇼 당쇄-폴리펩티드 복합체
WO2014162906A1 (ja) * 2013-03-30 2014-10-09 株式会社糖鎖工学研究所 糖鎖－ポリペプチド複合体
KR20160002835A (ko) * 2013-03-30 2016-01-08 가부시키가이샤 도우사 고가쿠 겐큐쇼 당쇄-폴리펩티드 복합체
US9981059B2 (en) 2013-03-30 2018-05-29 Glytech, Inc. Sugar chain-polypeptide complex
JP2019150582A (ja) * 2013-08-22 2019-09-12 アーチ・バイオサージェリー・インコーポレイテッド 流体の移動を制御するための移植可能なメッシュ
JP2016528018A (ja) * 2013-08-22 2016-09-15 アーチ・バイオサージェリー・インコーポレイテッド 流体の移動を制御するための移植可能なメッシュ
WO2015053338A1 (ja) * 2013-10-08 2015-04-16 学校法人東京理科大学 カチオン性ペプチドおよびそれを含む医薬組成物
WO2015145797A1 (ja) * 2014-03-28 2015-10-01 大塚化学株式会社 止血用医薬組成物
WO2017104723A1 (ja) * 2015-12-18 2017-06-22 株式会社スリー・ディー・マトリックス 止血用組成物、および、止血用組成物を用いた止血方法
JPWO2017104723A1 (ja) * 2015-12-18 2018-10-04 株式会社スリー・ディー・マトリックス 止血用組成物、および、止血用組成物を用いた止血方法
US11298397B2 (en) 2015-12-18 2022-04-12 3-D Matrix, Ltd. Hemostatic composition and hemostatic method using hemostatic composition
US12138291B2 (en) 2015-12-18 2024-11-12 3-D Matrix, Ltd. Hemostatic composition and hemostatic method using hemostatic composition
WO2024128081A1 (ja) * 2022-12-16 2024-06-20 東亞合成株式会社 合成ペプチド及び構築物

Also Published As

Publication number Publication date
JP5860437B2 (ja) 2016-02-16
JP6112621B2 (ja) 2017-04-12
CA2680824C (en) 2018-06-26
EP2146733B1 (en) 2020-11-25
ES2854674T3 (es) 2021-09-22
US20160324918A1 (en) 2016-11-10
WO2008113030A2 (en) 2008-09-18
JP2015028086A (ja) 2015-02-12
US20080274979A1 (en) 2008-11-06
DK2146733T3 (da) 2021-01-11
JP2013177467A (ja) 2013-09-09
WO2008113030A3 (en) 2009-04-02
EP2146733A2 (en) 2010-01-27
US9415084B2 (en) 2016-08-16
CA2680824A1 (en) 2008-09-18
JP2017105833A (ja) 2017-06-15

Similar Documents

Publication Publication Date Title
JP6112621B2 (ja) 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強
JP6441978B2 (ja) 癒着の予防および他のバリア適用のための組成物
JP5629241B2 (ja) 止血および他の生理学的活性を促進するための組成物および方法
HK1140431B (en) Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
HK1140431A (en) Treatment of leaky or damaged tight junctions and enhancing extracellular matrix
HK1184397A (en) Compositions for prevention of adhesions and other barrier applications
HK1184397B (en) Compositions for prevention of adhesions and other barrier applications
HK1112847B (en) Self-assembling peptides for promoting hemostasis

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110302

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110302

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120214

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121225

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130319

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130327

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20130730