JP2010513539A5 - - Google Patents
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- JP2010513539A5 JP2010513539A5 JP2009542980A JP2009542980A JP2010513539A5 JP 2010513539 A5 JP2010513539 A5 JP 2010513539A5 JP 2009542980 A JP2009542980 A JP 2009542980A JP 2009542980 A JP2009542980 A JP 2009542980A JP 2010513539 A5 JP2010513539 A5 JP 2010513539A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- heavy chain
- light chain
- amino acid
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87106906P | 2006-12-20 | 2006-12-20 | |
| PCT/US2007/078568 WO2008079466A1 (en) | 2006-12-20 | 2007-09-14 | Antibodies and methods for making and using them |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169145A Division JP2014028812A (ja) | 2006-12-20 | 2013-08-16 | 抗体とその製造法および使用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010513539A JP2010513539A (ja) | 2010-04-30 |
| JP2010513539A5 true JP2010513539A5 (enExample) | 2010-09-30 |
Family
ID=39536929
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009542980A Pending JP2010513539A (ja) | 2006-12-20 | 2007-09-14 | 抗体とその製造法および使用法 |
| JP2013169145A Pending JP2014028812A (ja) | 2006-12-20 | 2013-08-16 | 抗体とその製造法および使用法 |
| JP2015056137A Pending JP2015145394A (ja) | 2006-12-20 | 2015-03-19 | 抗体とその製造法および使用法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169145A Pending JP2014028812A (ja) | 2006-12-20 | 2013-08-16 | 抗体とその製造法および使用法 |
| JP2015056137A Pending JP2015145394A (ja) | 2006-12-20 | 2015-03-19 | 抗体とその製造法および使用法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8465741B2 (enExample) |
| EP (3) | EP2716657A3 (enExample) |
| JP (3) | JP2010513539A (enExample) |
| KR (2) | KR101546441B1 (enExample) |
| CN (2) | CN103709249B (enExample) |
| AU (1) | AU2007338607B2 (enExample) |
| BR (1) | BRPI0720565A2 (enExample) |
| CA (2) | CA2673725C (enExample) |
| MX (1) | MX2009006659A (enExample) |
| WO (2) | WO2008076487A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2673725C (en) * | 2006-12-20 | 2016-01-12 | Mmr Information Systems, Inc. | Antibodies and methods for making and using them |
| CA2744103C (en) | 2009-02-24 | 2018-01-02 | Esbatech, An Alcon Biomedical Research Unit Llc | Methods for identifying immunobinders of cell-surface antigens |
| AR080301A1 (es) | 2010-02-24 | 2012-03-28 | Immunogen Inc | Anticuerpos e inmunoconjugados del receptor 1 de folato y sus usos |
| US8481688B2 (en) * | 2010-05-11 | 2013-07-09 | Aveo Pharmaceuticals, Inc. | Anti-FGFR2 antibodies |
| CN105924519B (zh) | 2010-12-31 | 2019-08-23 | 生物蛋白有限公司 | 全面单克隆抗体产生 |
| MX344595B (es) * | 2010-12-31 | 2016-12-20 | Bioatla Llc | Humanizacion rapida de anticuerpos. |
| EP2673635A4 (en) * | 2011-02-07 | 2015-08-12 | Neotope Biosciences Ltd | IMMUNOTHERAPY THROUGH APOE |
| PL2694106T3 (pl) | 2011-04-01 | 2018-06-29 | Immunogen, Inc. | Sposoby zwiększania skuteczności terapii przeciwnowotworowej opartej na receptorze folr1 |
| AU2012328819B2 (en) | 2011-10-26 | 2017-08-03 | Elanco Tiergesundheit Ag | Monoclonal antibodies and methods of use |
| CN104010659A (zh) * | 2011-12-19 | 2014-08-27 | 洛克菲勒大学 | 非唾液酸化的抗炎多肽 |
| US12384848B2 (en) | 2011-12-19 | 2025-08-12 | The Rockefeller University | Anti-inflammatory polypeptides |
| KR20150046316A (ko) | 2012-08-31 | 2015-04-29 | 이뮤노젠 아이엔씨 | 엽산 수용체 1의 검출을 위한 진단성 검정 및 키트 |
| US10117933B2 (en) | 2012-11-28 | 2018-11-06 | Emergent Biosolutions Canada Inc. | Antibodies against Clostridium difficile |
| PT3038650T (pt) | 2013-08-30 | 2021-08-25 | Immunogen Inc | Anticorpos e ensaios para a deteção do recetor de folato 1 |
| AU2016226115B2 (en) | 2015-03-04 | 2021-03-25 | The Rockefeller University | Anti-inflammatory polypeptides |
| JP6880006B2 (ja) | 2015-09-17 | 2021-06-02 | イミュノジェン, インコーポレイテッド | 抗folr1免疫複合体を含む治療組み合わせ |
| EP3481862A4 (en) * | 2016-07-06 | 2020-08-12 | Celgene Corporation | LOW IMMUNOGENIC ANTIBODIES AND USES THEREOF |
| MA47691A (fr) * | 2017-08-03 | 2020-01-08 | Alector Llc | Anticorps anti-cd33 et leurs procédés d'utilisation |
| US20210213118A1 (en) * | 2018-08-31 | 2021-07-15 | Immune Biosolutions Inc | Antibodies specific for ntsr1 and uses thereof |
| CN111662382A (zh) * | 2019-03-06 | 2020-09-15 | 瑞阳(苏州)生物科技有限公司 | 特异结合cd3的抗体、抗原结合片段和单链抗体可变区片段及其应用 |
| JP7370569B2 (ja) * | 2019-08-07 | 2023-10-30 | 国立大学法人 大分大学 | アミロイドβタンパク質オリゴマーと結合するヒト化抗体 |
| JP7791836B2 (ja) * | 2020-04-24 | 2025-12-24 | メモリアル スローン ケタリング キャンサー センター | 抗cd3抗体及びその使用 |
| CA3202768A1 (en) * | 2020-12-07 | 2022-06-16 | Totient, Inc. | Systems and methods for producing disease-associated protein compositions |
| WO2025024323A1 (en) * | 2023-07-21 | 2025-01-30 | Bighat Biosciences, Inc. | P- and e-selectin-binding compositions and methods of use thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE255131T1 (de) * | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| ES2145004T3 (es) * | 1991-08-21 | 2000-07-01 | Novartis Ag | Derivados de anticuerpos. |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5840299A (en) | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| US5721121A (en) | 1995-06-06 | 1998-02-24 | Genentech, Inc. | Mammalian cell culture process for producing a tumor necrosis factor receptor immunoglobulin chimeric protein |
| US6537776B1 (en) | 1999-06-14 | 2003-03-25 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
| US6171820B1 (en) | 1995-12-07 | 2001-01-09 | Diversa Corporation | Saturation mutagenesis in directed evolution |
| US6562594B1 (en) | 1999-09-29 | 2003-05-13 | Diversa Corporation | Saturation mutagenesis in directed evolution |
| US6764835B2 (en) | 1995-12-07 | 2004-07-20 | Diversa Corporation | Saturation mutageneis in directed evolution |
| US5834597A (en) * | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| JP2000169393A (ja) * | 1998-09-30 | 2000-06-20 | Sankyo Co Ltd | 抗Fas抗体を含有する医薬 |
| PE20011338A1 (es) | 2000-05-26 | 2002-01-13 | Bristol Myers Squibb Co | Moleculas mutantes de ctla4 solubles |
| US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| RU2004127458A (ru) * | 2002-02-14 | 2005-10-27 | Иммуномедикс, Инк. (Us) | Анти-cd20 антитела, их гибридные белки и способы их использования |
| AR044388A1 (es) | 2003-05-20 | 2005-09-07 | Applied Molecular Evolution | Moleculas de union a cd20 |
| DK1629011T3 (da) * | 2003-05-31 | 2010-05-03 | Micromet Ag | Humane anti-humane-DC3-bindingsmolekyler |
| US20060228350A1 (en) * | 2003-08-18 | 2006-10-12 | Medimmune, Inc. | Framework-shuffling of antibodies |
| ZA200601699B (en) * | 2003-10-16 | 2007-05-30 | Micromet Ag | Multispecific deimmunized CD3-binders |
| PT1692182E (pt) * | 2003-11-05 | 2010-05-13 | Roche Glycart Ag | Anticorpos de cd20 com uma afinidade de ligação acrescida ao receptor fc e uma função efectora acrescida |
| EP1735000A2 (en) * | 2004-04-16 | 2006-12-27 | Genentech, Inc. | Method for augmenting b cell depletion |
| EP1773393A2 (en) | 2004-05-05 | 2007-04-18 | Genentech, Inc. | Preventing autoimmune disease by using an anti-cd20 antibody |
| EA012464B1 (ru) * | 2004-08-04 | 2009-10-30 | Эпплайд Молекьюлар Эволюшн, Инк. | Антитело против cd20 и его применение |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| EP1869192B1 (en) * | 2005-03-18 | 2016-01-20 | MedImmune, LLC | Framework-shuffling of antibodies |
| KR20080031001A (ko) * | 2005-06-02 | 2008-04-07 | 아스트라제네카 아베 | Cd20에 대한 항체 및 그의 용도 |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| US10155816B2 (en) * | 2005-11-28 | 2018-12-18 | Genmab A/S | Recombinant monovalent antibodies and methods for production thereof |
| CA2673725C (en) | 2006-12-20 | 2016-01-12 | Mmr Information Systems, Inc. | Antibodies and methods for making and using them |
-
2007
- 2007-09-14 CA CA2673725A patent/CA2673725C/en not_active Expired - Fee Related
- 2007-09-14 EP EP13198591.3A patent/EP2716657A3/en not_active Withdrawn
- 2007-09-14 EP EP07842553A patent/EP2121756A4/en not_active Withdrawn
- 2007-09-14 CA CA2832111A patent/CA2832111A1/en not_active Abandoned
- 2007-09-14 BR BRPI0720565-1A2A patent/BRPI0720565A2/pt not_active IP Right Cessation
- 2007-09-14 KR KR1020137022383A patent/KR101546441B1/ko not_active Expired - Fee Related
- 2007-09-14 EP EP13198631.7A patent/EP2716658A3/en not_active Withdrawn
- 2007-09-14 KR KR1020097015196A patent/KR101378302B1/ko not_active Expired - Fee Related
- 2007-09-14 JP JP2009542980A patent/JP2010513539A/ja active Pending
- 2007-09-14 AU AU2007338607A patent/AU2007338607B2/en not_active Ceased
- 2007-09-14 WO PCT/US2007/078566 patent/WO2008076487A2/en not_active Ceased
- 2007-09-14 CN CN201310355119.6A patent/CN103709249B/zh not_active Expired - Fee Related
- 2007-09-14 US US11/855,943 patent/US8465741B2/en not_active Expired - Fee Related
- 2007-09-14 WO PCT/US2007/078568 patent/WO2008079466A1/en not_active Ceased
- 2007-09-14 MX MX2009006659A patent/MX2009006659A/es active IP Right Grant
- 2007-09-14 CN CN200780051557.6A patent/CN101675074B/zh not_active Expired - Fee Related
-
2009
- 2009-06-18 US US12/487,422 patent/US8945550B2/en not_active Expired - Fee Related
-
2013
- 2013-04-19 US US13/866,120 patent/US20130287766A1/en not_active Abandoned
- 2013-08-16 JP JP2013169145A patent/JP2014028812A/ja active Pending
-
2015
- 2015-03-19 JP JP2015056137A patent/JP2015145394A/ja active Pending