JP2010510323A5 - - Google Patents

Download PDF

Info

Publication number
JP2010510323A5
JP2010510323A5 JP2009538506A JP2009538506A JP2010510323A5 JP 2010510323 A5 JP2010510323 A5 JP 2010510323A5 JP 2009538506 A JP2009538506 A JP 2009538506A JP 2009538506 A JP2009538506 A JP 2009538506A JP 2010510323 A5 JP2010510323 A5 JP 2010510323A5
Authority
JP
Japan
Prior art keywords
antibody
pharmaceutical composition
composition according
effective amount
therapeutically effective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009538506A
Other languages
English (en)
Japanese (ja)
Other versions
JP5410293B2 (ja
JP2010510323A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/085402 external-priority patent/WO2008064321A2/en
Publication of JP2010510323A publication Critical patent/JP2010510323A/ja
Publication of JP2010510323A5 publication Critical patent/JP2010510323A5/ja
Application granted granted Critical
Publication of JP5410293B2 publication Critical patent/JP5410293B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009538506A 2006-11-21 2007-11-21 Ｇｍ−ｃｓｆアンタゴニストを用いて慢性炎症性疾患を治療する方法 Expired - Fee Related JP5410293B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86078006P 2006-11-21 2006-11-21
US60/860,780 2006-11-21
US90274207P 2007-02-21 2007-02-21
US60/902,742 2007-02-21
PCT/US2007/085402 WO2008064321A2 (en) 2006-11-21 2007-11-21 Methods of treating chronic inflammatory diseases using a gm-csf antagonist

Publications (3)

Publication Number Publication Date
JP2010510323A JP2010510323A (ja) 2010-04-02
JP2010510323A5 true JP2010510323A5 (enExample) 2011-01-13
JP5410293B2 JP5410293B2 (ja) 2014-02-05

Family

ID=39386167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009538506A Expired - Fee Related JP5410293B2 (ja) 2006-11-21 2007-11-21 Ｇｍ−ｃｓｆアンタゴニストを用いて慢性炎症性疾患を治療する方法

Country Status (15)

Country Link
US (2) US20080206241A1 (enExample)
EP (2) EP2402013A1 (enExample)
JP (1) JP5410293B2 (enExample)
KR (1) KR101517251B1 (enExample)
CN (2) CN101605547A (enExample)
AU (1) AU2007323541B2 (enExample)
BR (1) BRPI0719109A2 (enExample)
CA (1) CA2670288C (enExample)
EA (1) EA200900709A1 (enExample)
ES (1) ES2432173T3 (enExample)
IL (1) IL198829A0 (enExample)
MX (1) MX2009005398A (enExample)
NZ (1) NZ598345A (enExample)
SG (1) SG176503A1 (enExample)
WO (1) WO2008064321A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101605547A (zh) 2006-11-21 2009-12-16 卡罗拜奥斯制药公司 使用gm-csf拮抗剂治疗慢性炎症疾病的方法
US8680019B2 (en) * 2007-08-10 2014-03-25 Protelica, Inc. Universal fibronectin Type III binding-domain libraries
AU2008287426B2 (en) * 2007-08-10 2014-06-26 Protelica, Inc. Universal fibronectin type III binding-domain libraries
US8470966B2 (en) 2007-08-10 2013-06-25 Protelica, Inc. Universal fibronectin type III binding-domain libraries
TW200918553A (en) 2007-09-18 2009-05-01 Amgen Inc Human GM-CSF antigen binding proteins
MX2010005291A (es) 2007-11-13 2010-11-12 Evec Inc Anticuerpos monoclonales que se unen a hgm-csf y composiciones medicas que comprenden los mismos.
BRPI0907220A2 (pt) * 2008-01-15 2019-02-26 Kalobios Pharmaceuticals, Inc. métodos de tratar distúrbios de perda óssea usando um antagonista de gm-csf
CA2720614A1 (en) * 2008-04-07 2009-10-15 Kalobios Pharmaceuticals, Inc. Neutralization of gm-csf for the treatment of heart failure
CN102037016B (zh) 2008-04-28 2015-06-03 卡罗拜奥斯制药公司 针对粒细胞巨噬细胞集落刺激因子的抗体
ES2978209T3 (es) 2008-12-22 2024-09-09 Univ Melbourne Tratamiento del dolor
AU2015224416B2 (en) * 2008-12-22 2017-04-20 The University Of Melbourne Osteoarthritis treatment
DK2376121T4 (da) 2008-12-22 2021-08-16 Univ Melbourne Slidgigtbehandling
WO2010093814A1 (en) * 2009-02-11 2010-08-19 Kalobios Pharmaceuticals, Inc. Methods of treating dementia using a gm-csf antagonist
SG175305A1 (en) * 2009-04-23 2011-11-28 Theraclone Sciences Inc Granulocyte-macrophage colony-stimulating factor (gm-csf) neutralizing antibodies
EP2427495A1 (en) * 2009-05-05 2012-03-14 MorphoSys AG Treatment for multiple sclerosis
CN103827143A (zh) * 2011-07-06 2014-05-28 莫弗系统股份公司 抗cd20抗体和抗gm-csf抗体的治疗性组合产品及其用途
KR20210021153A (ko) * 2012-09-20 2021-02-24 모르포시스 아게 류마티스 관절염에 대한 치료
EP3916013A1 (en) 2012-09-20 2021-12-01 MorphoSys AG Treatment for rheumatoid arthritis with anti-gm-csf antibody
AR093297A1 (es) * 2012-10-31 2015-05-27 Amgen Res Munich Gmbh Formulacion liquida que comprende un compuesto neutralizante de gm-csf
RU2714919C2 (ru) 2013-08-30 2020-02-21 Такеда Гмбх Антитела, нейтрализующие gm-csf, для применения в лечении ревматоидного артрита или в качестве анальгетиков
JP6360696B2 (ja) * 2014-03-18 2018-07-18 日本光電工業株式会社 血液検査装置および血液検査方法
CA2948944A1 (en) * 2014-05-19 2015-11-26 Medimmune Limited Treatment for rheumatoid arthritis
WO2018031967A1 (en) * 2016-08-12 2018-02-15 L.E.A.F. Holdings Group Llc Polyglutamated antifolates and uses thereof
PL3328887T3 (pl) * 2016-09-19 2021-12-27 I-Mab Biopharma (Hangzhou) Co., Ltd. Przeciwciała anty-gm-csf i ich zastosowania
US10927168B2 (en) 2017-10-02 2021-02-23 Humanicen, Inc. Method of reducing tumor relapse rate in immunotherapy by administration of lenzilumab
US10870703B2 (en) 2017-10-02 2020-12-22 Humanigen, Inc. Methods of treating immunotherapy-related toxicity using a GM-CSF antagonist
US10899831B2 (en) 2017-10-02 2021-01-26 Humanigen, Inc. Method of reducing the level of non-GM-CSF cytokines/chemokines in immunotherapy-related toxicity
US11130805B2 (en) 2017-10-02 2021-09-28 Humanigen, Inc. Methods of treating CART-T cell therapy-induced neuroinflammation using a GM-CSF antagonist
CA3116412A1 (en) * 2018-10-31 2020-05-07 Humanigen, Inc. Materials and methods for treating cancer
KR20230005139A (ko) * 2020-03-08 2023-01-09 휴머니건, 아이엔씨. 코로나바이러스 감염 및 이로 인한 염증-유발된 폐 손상의 치료 방법
JP2023551549A (ja) * 2020-12-04 2023-12-08 シーエスエル イノベーション プロプライアタリー リミティド 炎症性皮膚状態を治療する方法
WO2022192093A1 (en) * 2021-03-08 2022-09-15 Humanigen, Inc. Methods for treating coronavirus infection and resulting inflammation-induced lung injury
WO2023138499A1 (zh) * 2022-01-20 2023-07-27 舒泰神（北京）生物制药股份有限公司 一种特异性地识别粒细胞-巨噬细胞集落刺激因子受体的抗体制剂及其应用
CN117547474A (zh) * 2022-08-03 2024-02-13 苏州隽德生物科技有限公司 含磺化杯芳烃的护肤品组合物、药用组合物、及磺化杯芳烃的用途

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
JPS6412935A (en) 1987-07-02 1989-01-17 Mitsubishi Electric Corp Constant-speed travel device for vehicle
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
CA2062975A1 (en) * 1989-07-14 1991-01-15 Gail F. Seelig Antagonists of gm-csf derived from the carboxyl terminus
WO1994009149A1 (en) 1990-08-10 1994-04-28 Amrad Corporation Limited Monoclonal antibody
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
HU230048B1 (hu) 1996-02-09 2015-06-29 Abbvie Biotechnology Ltd Humán TNFalfa-kötő antitestek alkalmazása
US5770380A (en) 1996-09-13 1998-06-23 University Of Pittsburgh Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold
EP1051432B1 (en) 1998-12-08 2007-01-24 Biovation Limited Method for reducing immunogenicity of proteins
US6818418B1 (en) 1998-12-10 2004-11-16 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
US7115396B2 (en) 1998-12-10 2006-10-03 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
US7108852B2 (en) * 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
US7455836B2 (en) * 2000-05-08 2008-11-25 The University Of Melbourne Method of treatment and agents useful for same
JP2006500905A (ja) * 2002-02-13 2006-01-12 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ヒト化ｇｍ−ｃｓｆ抗体
GB0224082D0 (en) * 2002-10-16 2002-11-27 Celltech R&D Ltd Biological products
AU2004219592C1 (en) * 2003-03-12 2011-02-24 Genentech, Inc. Use of Bv8 and/or EG-VEGF to promote hematopoiesis
EP1653968A4 (en) * 2003-07-23 2006-09-06 Synta Pharmaceuticals Corp METHOD FOR MODULATING CALCIUMION RELIEF ACTIVATED CALCIUMION CHANNELS
JP4782700B2 (ja) * 2004-01-20 2011-09-28 カロバイオス ファーマシューティカルズ インコーポレイティッド 最低限必須な結合決定基を用いた抗体特異性の移入
ATE502630T1 (de) * 2004-07-16 2011-04-15 Kyorin Seiyaku Kk Verfahren zur effektiven anwendung eines medikaments und verfahren zur prävention von nebenwirkungen
EP2343380B1 (en) * 2004-11-16 2019-06-12 Humanigen, Inc. Immunoglobulin variable region cassette exchange
NZ564027A (en) 2005-05-18 2011-06-30 Morphosys Ag Anti-GM-CSF antibodies and uses therefor
US20080305079A1 (en) * 2006-01-06 2008-12-11 Mount Sinai School Of Medicine Of New York University Myeloid Suppressor Cells, Methods For Preparing Them, and Methods For Using Them For Treating Autoimmunity
RS55526B1 (sr) * 2006-02-08 2017-05-31 Morphotek Inc Antigenski gm-csf peptidi i antitela gm-csf
ES2395839T3 (es) * 2006-03-27 2013-02-15 Medimmune Limited Miembro de unión para el receptor GM-CSF
DE102006033837A1 (de) * 2006-07-21 2008-01-31 Medac Gesellschaft für klinische Spezialpräparate m.b.H Konzentrierte Methotrexat-Lösungen
CN101605547A (zh) 2006-11-21 2009-12-16 卡罗拜奥斯制药公司 使用gm-csf拮抗剂治疗慢性炎症疾病的方法

Similar Documents

Publication Publication Date Title
RU2474588C2 (ru) Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения
US12006359B2 (en) Methods for altering body composition by administering anti-pro/latent myostatin antibodies
JP5537740B2 (ja) Ｉｌ−１７アンタゴニストを用いて乾癬を治療する方法
US20140212423A1 (en) Blood-brain barrier penetrating dual specific binding proteins
US20160002343A1 (en) Blood-brain barrier (bbb) penetrating dual specific binding proteins for treating brain and neurological diseases
CN104903352A (zh) 多价结合蛋白组合物
JP2019514844A5 (enExample)
JP2017512765A5 (enExample)
JP2017535257A5 (enExample)
JP2020513791A5 (enExample)
JP2017501711A5 (enExample)
RU2016129247A (ru) Антитела с двойной специфичностью
JP2014533659A5 (enExample)
JP2004536072A5 (enExample)
HRP20220405T1 (hr) Protutijela protiv ngf i njihova upotreba
JP2020536532A5 (enExample)
WO2009140348A4 (en) Anti-il-6/il-6r antibodies and methods of use thereof
JP2011520898A5 (enExample)
JP2017537105A (ja) 瘻孔を伴うクローン病の治療用ベドリズマブ
JP2010520290A5 (enExample)
JP2016094424A5 (enExample)
JP2015509960A5 (enExample)
JP2013508292A5 (enExample)
JP2017507131A5 (enExample)
US20230235069A1 (en) Treatment of atopic dermatitis