JP2010509570A - エクスビボフローサイトメトリーの方法および装置 - Google Patents
エクスビボフローサイトメトリーの方法および装置 Download PDFInfo
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- JP2010509570A JP2010509570A JP2009535333A JP2009535333A JP2010509570A JP 2010509570 A JP2010509570 A JP 2010509570A JP 2009535333 A JP2009535333 A JP 2009535333A JP 2009535333 A JP2009535333 A JP 2009535333A JP 2010509570 A JP2010509570 A JP 2010509570A
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- 0 CC(CCC(N[C@@](Cc1ccccc1)C(N[C@@](CS)C(O)=O)=O)=O)OCCC(C)OCCNC(CC[C@](*C(N[C@@](CCC(O)=O)C(O)=O)=O)C(O)=O)C=O Chemical compound CC(CCC(N[C@@](Cc1ccccc1)C(N[C@@](CS)C(O)=O)=O)=O)OCCC(C)OCCNC(CC[C@](*C(N[C@@](CCC(O)=O)C(O)=O)=O)C(O)=O)C=O 0.000 description 6
- OKFZDFYVMDTLJJ-FSDJUJTCSA-N C[C@H](CSC(CC(N1c(cc2)cc(C(O)=O)c2C(c(cc(c(O)c2)F)c2O2)=C(C=C3F)C2=CC3=O)=O)C1=O)NC([C@H](Cc1ccccc1)NC(CCCOCCC(C)OCCNC(CC[C@@H](C(O)=O)NC(N[C@@](C)(CCC(O)=O)C(O)=O)=O)=O)=O)=O Chemical compound C[C@H](CSC(CC(N1c(cc2)cc(C(O)=O)c2C(c(cc(c(O)c2)F)c2O2)=C(C=C3F)C2=CC3=O)=O)C1=O)NC([C@H](Cc1ccccc1)NC(CCCOCCC(C)OCCNC(CC[C@@H](C(O)=O)NC(N[C@@](C)(CCC(O)=O)C(O)=O)=O)=O)=O)=O OKFZDFYVMDTLJJ-FSDJUJTCSA-N 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/1438—Using two lasers in succession
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85666706P | 2006-11-03 | 2006-11-03 | |
| US95656207P | 2007-08-17 | 2007-08-17 | |
| PCT/US2007/023176 WO2008057437A2 (en) | 2006-11-03 | 2007-11-02 | Ex vivo flow cytometry method and device |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014144399A Division JP2014238406A (ja) | 2006-11-03 | 2014-07-14 | エクスビボフローサイトメトリーの方法および装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010509570A true JP2010509570A (ja) | 2010-03-25 |
| JP2010509570A5 JP2010509570A5 (enExample) | 2012-01-12 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535333A Ceased JP2010509570A (ja) | 2006-11-03 | 2007-11-02 | エクスビボフローサイトメトリーの方法および装置 |
| JP2014144399A Pending JP2014238406A (ja) | 2006-11-03 | 2014-07-14 | エクスビボフローサイトメトリーの方法および装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014144399A Pending JP2014238406A (ja) | 2006-11-03 | 2014-07-14 | エクスビボフローサイトメトリーの方法および装置 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8685752B2 (enExample) |
| EP (1) | EP2087337A4 (enExample) |
| JP (2) | JP2010509570A (enExample) |
| CA (1) | CA2668197A1 (enExample) |
| WO (1) | WO2008057437A2 (enExample) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58102538A (ja) * | 1981-12-14 | 1983-06-18 | Fujitsu Ltd | 半導体装置の製造方法 |
| JP2013104876A (ja) * | 2011-11-14 | 2013-05-30 | Leica Microsystems Cms Gmbh | 試料における励起状態の寿命を測定するための方法 |
| JP2013117529A (ja) * | 2011-12-01 | 2013-06-13 | Leica Microsystems Cms Gmbh | 試料を検査するための方法および機器 |
| JP2018535925A (ja) * | 2015-09-09 | 2018-12-06 | オン ターゲット ラボラトリーズ エルエルシー | Psma標的化nir色素およびその使用 |
| JP2019138838A (ja) * | 2018-02-14 | 2019-08-22 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
| US11360078B2 (en) | 2016-09-29 | 2022-06-14 | Sumitomo Rubber Industries, Ltd. | Medical analysis device and cell analysis method |
| US11573232B2 (en) | 2018-02-14 | 2023-02-07 | Sumitomo Rubber Industries, Ltd. | Method for capturing specific cells |
| US11614440B2 (en) | 2019-01-24 | 2023-03-28 | Sumitomo Rubber Industries, Ltd. | Specific cell fractionating and capturing methods |
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| RU2316349C2 (ru) * | 2001-05-02 | 2008-02-10 | Пердью Рисерч Фаундейшн | Лечение и диагностика заболеваний, опосредованных макрофагами |
| US8043602B2 (en) * | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| US8043603B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| CA2527196C (en) | 2003-05-30 | 2012-10-16 | Purdue Research Foundation | Diagnostic method for atherosclerosis |
| US20050232919A1 (en) | 2004-02-12 | 2005-10-20 | Morphotek, Inc. | Monoclonal antibodies that specifically block biological activity of a tumor antigen |
| EP1789391B1 (en) | 2004-07-23 | 2017-06-28 | Endocyte, Inc. | Bivalent linkers and conjugates thereof |
| ES2731448T3 (es) * | 2004-12-23 | 2019-11-15 | Purdue Research Foundation | Procedimiento de análisis por imagen mediante tomografía por emisión de positrones |
| JP2009521206A (ja) | 2005-04-22 | 2009-06-04 | モルフォテック、インク. | 免疫エフェクター活性を有する葉酸受容体アルファ陽性細胞に内部移行する抗体 |
| WO2007006041A2 (en) | 2005-07-05 | 2007-01-11 | Purdue Research Foundation | Imaging and therapeutic method using monocytes |
| WO2007038346A2 (en) | 2005-09-23 | 2007-04-05 | Purdue Research Foundation | Multiphoton in vivo flow cytometry method and device |
| US8685752B2 (en) | 2006-11-03 | 2014-04-01 | Purdue Research Foundation | Ex vivo flow cytometry method and device |
| JP5869205B2 (ja) | 2007-02-07 | 2016-02-24 | パーデュー・リサーチ・ファウンデーションPurdue Research Foundation | ポジトロン放射断層画像法 |
| CN101678124A (zh) | 2007-03-14 | 2010-03-24 | 恩多塞特公司 | 结合配体连接的微管溶素递药缀合物 |
| US8961926B2 (en) * | 2007-05-25 | 2015-02-24 | Purdue Research Foundation | Method of imaging localized infections |
| EP3569251A1 (en) | 2007-06-25 | 2019-11-20 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| EP2921482B1 (en) * | 2007-06-26 | 2018-09-05 | The Johns Hopkins University | Labeled inhibitors of prostate-specific membrane antigen (psma), biological evaluation, and use as imaging agents |
| AU2015203742B2 (en) * | 2007-06-26 | 2016-12-01 | The Johns Hopkins University | Labeled inhibitors of prostate specific membrane antigen (psma), biological evaluation, and use as imaging agents |
| US9193763B2 (en) | 2007-08-17 | 2015-11-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| WO2010039802A2 (en) * | 2008-09-30 | 2010-04-08 | Northwestern University | Methods and compositions for isolating nucleic acid |
| WO2010045598A2 (en) * | 2008-10-17 | 2010-04-22 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
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| US12083191B2 (en) | 2009-10-19 | 2024-09-10 | Case Western Reserve University | Composition and methods for imaging cells |
| WO2011099565A1 (ja) * | 2010-02-10 | 2011-08-18 | シスメックス株式会社 | 血液中癌細胞の検出方法及びそれに用いるプログラム |
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| JPH11287799A (ja) * | 1997-11-22 | 1999-10-19 | Stephen C Wardlaw | 全血中の異常な有核細胞の検出、同定、計数及び確認方法 |
| JP2002503814A (ja) * | 1998-02-12 | 2002-02-05 | イムニベスト・コーポレイション | 循環ガン細胞の迅速かつ効率的な単離のための方法および試薬 |
| JP2004511250A (ja) * | 2000-10-16 | 2004-04-15 | ギリード・サイエンシズ・インコーポレーテッド | 前立腺特異的膜抗原に対する核酸リガンド |
| JP2004530678A (ja) * | 2001-05-02 | 2004-10-07 | パーデュー・リサーチ・ファウンデーション | マクロファージが仲介する疾患の治療および診断 |
| JP2005519078A (ja) * | 2002-02-27 | 2005-06-30 | ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション | 急性骨髄性白血病の治療方法 |
| WO2005116234A2 (en) * | 2004-04-16 | 2005-12-08 | University Of Massachusetts | Detection and quantification of intracellular pathogens |
| WO2006034046A2 (en) * | 2004-09-17 | 2006-03-30 | The Regents Of The University Of Michigan | Quantitative two-photon flow cytometry |
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| JP7170254B2 (ja) | 2018-02-14 | 2022-11-14 | 住友ゴム工業株式会社 | 特定細胞捕捉方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2008057437A2 (en) | 2008-05-15 |
| WO2008057437B1 (en) | 2008-11-27 |
| US9279813B2 (en) | 2016-03-08 |
| CA2668197A1 (en) | 2008-05-15 |
| WO2008057437A9 (en) | 2008-08-14 |
| WO2008057437A3 (en) | 2008-10-16 |
| US20140234866A1 (en) | 2014-08-21 |
| US8685752B2 (en) | 2014-04-01 |
| JP2014238406A (ja) | 2014-12-18 |
| EP2087337A4 (en) | 2010-09-08 |
| US20100055735A1 (en) | 2010-03-04 |
| EP2087337A2 (en) | 2009-08-12 |
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