|
EP0475255A3
(en)
*
|
1990-09-12 |
1993-04-14 |
F. Hoffmann-La Roche Ag |
Process for the preparation of optically pure (s)-alpha-((tert-butylsulfonyl)methyl)hydro cinnamic acid
|
|
KR100509388B1
(ko)
|
1996-10-18 |
2005-08-23 |
버텍스 파마슈티칼스 인코포레이티드 |
세린 프로테아제, 특히 간염 c 바이러스 ns3 프로테아제의 저해제
|
|
ES2234144T3
(es)
|
1997-08-11 |
2005-06-16 |
Boehringer Ingelheim (Canada) Ltd. |
Analogos de peptidos inhibidores de la hepatitis c.
|
|
WO1999007733A2
(en)
|
1997-08-11 |
1999-02-18 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor peptides
|
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
|
AR022061A1
(es)
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
|
UA74546C2
(en)
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
DK1385870T3
(da)
|
2000-07-21 |
2010-07-05 |
Schering Corp |
Peptider som inhibitorer af NS3-serinprotease fra hepatitis C-virus
|
|
DE60119968T2
(de)
|
2000-11-20 |
2007-01-18 |
Bristol-Myers Squibb Co. |
Hepatitis c tripeptid inhibitoren
|
|
US6867185B2
(en)
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
|
CA2369711A1
(en)
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
|
CA2369970A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
|
US20060199773A1
(en)
|
2002-05-20 |
2006-09-07 |
Sausker Justin B |
Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt
|
|
JP4271148B2
(ja)
|
2002-05-20 |
2009-06-03 |
ブリストル−マイヤーズ スクイブ カンパニー |
置換シクロアルキルp1’c型肝炎ウイルスインヒビター
|
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
|
WO2004032827A2
(en)
|
2002-05-20 |
2004-04-22 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
JP4312711B2
(ja)
|
2002-05-20 |
2009-08-12 |
ブリストル−マイヤーズ スクイブ カンパニー |
ヘテロ環式スルホンアミドc型肝炎ウイルス阻害剤
|
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
|
US7601709B2
(en)
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
|
CA2515216A1
(en)
|
2003-02-07 |
2004-08-26 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis c serine protease inhibitors
|
|
US6908901B2
(en)
|
2003-03-05 |
2005-06-21 |
Boehringer Ingelheim International, Gmbh |
Hepatitis C inhibitor peptide analogs
|
|
CA2516016C
(en)
|
2003-03-05 |
2012-05-29 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibiting compounds
|
|
EP1613353A1
(en)
|
2003-04-02 |
2006-01-11 |
Boehringer Ingelheim International GmbH |
Pharmaceutical compositions for hepatitis c viral protease inhibitors
|
|
JP4733023B2
(ja)
|
2003-04-16 |
2011-07-27 |
ブリストル−マイヤーズ スクイブ カンパニー |
C型肝炎ウイルスの大環状イソキノリンペプチド阻害剤
|
|
KR101031825B1
(ko)
|
2003-04-18 |
2011-04-29 |
이난타 파마슈티칼스, 인코포레이티드 |
거대고리형 퀴녹살리닐 c형 간염 세린 단백질분해효소억제제
|
|
CL2004001161A1
(es)
|
2003-05-21 |
2005-04-08 |
Boehringer Ingelheim Int |
Compuestos describe compuestos derivados de quinolina; composicion farmaceutica; y su uso para tratar una enfermedad causada por el virus de la hepatitis c.
|
|
WO2004113365A2
(en)
|
2003-06-05 |
2004-12-29 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c serine protease tri-peptide inhibitors
|
|
US7125845B2
(en)
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
|
ES2361997T3
(es)
|
2003-09-22 |
2011-06-27 |
Boehringer Ingelheim International Gmbh |
Péptidos macrocíclicos activos contra el virus de la hepatitis c.
|
|
WO2005037860A2
(en)
|
2003-10-10 |
2005-04-28 |
Vertex Pharmaceuticals Incoporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
WO2005037214A2
(en)
|
2003-10-14 |
2005-04-28 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
MXPA06005683A
(es)
|
2003-11-20 |
2006-12-14 |
Schering Corp |
Inhibidores despeptidizados de la proteasa ns3 del virus de la hepatitis c.
|
|
ATE495185T1
(de)
|
2004-01-21 |
2011-01-15 |
Boehringer Ingelheim Int |
Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus
|
|
JP4902361B2
(ja)
|
2004-01-30 |
2012-03-21 |
メディヴィル・アクチエボラーグ |
Hcvns−3セリンプロテアーゼインヒビター
|
|
AP2006003763A0
(en)
|
2004-03-30 |
2006-10-31 |
Intermune Inc |
Macrocyclic compounds as inhibitors of viral replication
|
|
WO2006016930A2
(en)
|
2004-05-14 |
2006-02-16 |
Intermune, Inc. |
Methods for treating hcv infection
|
|
CA2568008C
(en)
|
2004-05-25 |
2014-01-28 |
Boehringer Ingelheim International Gmbh |
Process for preparing acyclic hcv protease inhibitors
|
|
CA2556669C
(en)
|
2004-06-28 |
2012-05-01 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
|
RS51974B
(sr)
|
2004-07-16 |
2012-02-29 |
Gilead Sciences Inc. |
Antivirusna jedinjenja
|
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
JP4914355B2
(ja)
|
2004-07-20 |
2012-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類似体
|
|
ATE513844T1
(de)
|
2004-08-27 |
2011-07-15 |
Schering Corp |
Acylsulfonamidverbindungen als inhibitoren der ns3-serinprotease des hepatitis-c-virus
|
|
WO2006033878A1
(en)
|
2004-09-17 |
2006-03-30 |
Boehringer Ingelheim International, Gmbh |
Process for preparing macrocyclic hcv protease inhibitors
|
|
WO2007001406A2
(en)
|
2004-10-05 |
2007-01-04 |
Chiron Corporation |
Aryl-containing macrocyclic compounds
|
|
MX2007004783A
(es)
|
2004-10-21 |
2007-05-11 |
Pfizer |
Inhibidores de la proteasa del virus de la hepatitis c, y composiciones y tratamientos que los usan.
|
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2006096652A2
(en)
|
2005-03-08 |
2006-09-14 |
Boehringer Ingelheim International Gmbh |
Process for preparing macrocyclic compounds
|
|
AU2006242475B2
(en)
|
2005-05-02 |
2011-07-07 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2006130552A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis c virus
|
|
WO2006130627A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods for treating hepatitis c
|
|
US20070004635A1
(en)
|
2005-06-02 |
2007-01-04 |
Schering Corporation |
Method of treating interferon non-responders using HCV protease inhibitor
|
|
US20060276404A1
(en)
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
|
US20060276407A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US20060281689A1
(en)
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
|
US20070021351A1
(en)
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
|
US20060287248A1
(en)
|
2005-06-02 |
2006-12-21 |
Schering Corporation |
Asymmetric dosing methods
|
|
NZ563365A
(en)
|
2005-06-02 |
2011-02-25 |
Schering Corp |
Combination of HCV protease inhibitors with a surfactant
|
|
AU2006252519B2
(en)
|
2005-06-02 |
2012-08-30 |
Merck Sharp & Dohme Corp. |
HCV protease inhibitors in combination with food
|
|
AU2006252623A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation useful for treating disorders associated with hepatitis C virus
|
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
TW200738742A
(en)
|
2005-07-14 |
2007-10-16 |
Gilead Sciences Inc |
Antiviral compounds
|
|
TWI389908B
(zh)
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
|
JP2009501732A
(ja)
|
2005-07-20 |
2009-01-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類似体
|
|
TWI387603B
(zh)
|
2005-07-20 |
2013-03-01 |
Merck Sharp & Dohme |
Hcv ns3蛋白酶抑制劑
|
|
MX2008001166A
(es)
|
2005-07-25 |
2008-03-18 |
Intermune Inc |
Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c.
|
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
ES2373685T3
(es)
|
2005-07-29 |
2012-02-07 |
Tibotec Pharmaceuticals |
Inhibidores macrocíclicos del virus de la hepatitis c.
|
|
TWI393723B
(zh)
|
2005-07-29 |
2013-04-21 |
Tibotec Pharm Ltd |
C型肝炎病毒之大環抑制劑(九)
|
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
PE20070343A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
|
JP5230416B2
(ja)
|
2005-07-29 |
2013-07-10 |
テイボテク・フアーマシユーチカルズ |
C型肝炎ウイルスの大員環状阻害剤
|
|
CA2617099C
(en)
|
2005-07-29 |
2014-03-25 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
|
WO2007014922A1
(en)
|
2005-07-29 |
2007-02-08 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
|
US7700552B2
(en)
|
2005-07-29 |
2010-04-20 |
Medivir Ab |
Macrocyclic inhibitors of hepatitis C virus
|
|
CN101273042B
(zh)
|
2005-07-29 |
2013-11-06 |
泰博特克药品有限公司 |
丙型肝炎病毒的大环抑制剂
|
|
EP1915382A2
(en)
|
2005-08-01 |
2008-04-30 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
|
BRPI0614205A2
(pt)
|
2005-08-01 |
2016-11-22 |
Merck & Co Inc |
composto, composição farmacêutica, e, uso de composto
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
AU2006301966A1
(en)
|
2005-10-11 |
2007-04-19 |
Array Biopharma, Inc. |
Compounds and methods for inhibiting hepatitis C viral replication
|
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2007082131A1
(en)
|
2006-01-09 |
2007-07-19 |
Bristol-Myers Squibb Company |
Process for the preparation of hydroxy substituted heterocycles
|
|
US20090220457A1
(en)
|
2006-03-03 |
2009-09-03 |
Lahser Frederick C |
Combinations comprising hcv protease inhibitor(s) and hcv ires inhibitor(s), and methods of treatment related thereto
|
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
US20070281884A1
(en)
|
2006-06-06 |
2007-12-06 |
Ying Sun |
Macrocyclic oximyl hepatitis C protease inhibitors
|
|
US7635683B2
(en)
|
2006-08-04 |
2009-12-22 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl tripeptide hepatitis C virus inhibitors
|
|
US7582605B2
(en)
|
2006-08-11 |
2009-09-01 |
Enanta Pharmaceuticals, Inc. |
Phosphorus-containing hepatitis C serine protease inhibitors
|
|
US7605126B2
(en)
|
2006-08-11 |
2009-10-20 |
Enanta Pharmaceuticals, Inc. |
Acylaminoheteroaryl hepatitis C virus protease inhibitors
|
|
US20080107625A1
(en)
*
|
2006-11-01 |
2008-05-08 |
Bristol-Myers Squibb Company |
Inhibitors of Hepatitis C Virus
|
|
US20080107623A1
(en)
*
|
2006-11-01 |
2008-05-08 |
Bristol-Myers Squibb Company |
Inhibitors of Hepatitis C Virus
|