JP2010506844A5 - - Google Patents
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- Publication number
- JP2010506844A5 JP2010506844A5 JP2009532504A JP2009532504A JP2010506844A5 JP 2010506844 A5 JP2010506844 A5 JP 2010506844A5 JP 2009532504 A JP2009532504 A JP 2009532504A JP 2009532504 A JP2009532504 A JP 2009532504A JP 2010506844 A5 JP2010506844 A5 JP 2010506844A5
- Authority
- JP
- Japan
- Prior art keywords
- leu
- arg
- val
- glu
- ser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- MISPMPVBBRXIDJ-GKAPJAKFSA-N CC([C@H](CCCCNC=O)NC)O Chemical compound CC([C@H](CCCCNC=O)NC)O MISPMPVBBRXIDJ-GKAPJAKFSA-N 0.000 description 1
- 0 CCCCN(*C)I(C)O Chemical compound CCCCN(*C)I(C)O 0.000 description 1
- AJIJHIJNLPIHJQ-ZETCQYMHSA-N CCC[C@@H](C(C)=O)NC Chemical compound CCC[C@@H](C(C)=O)NC AJIJHIJNLPIHJQ-ZETCQYMHSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82938306P | 2006-10-13 | 2006-10-13 | |
| US60/829,383 | 2006-10-13 | ||
| PCT/US2007/080367 WO2008048784A1 (en) | 2006-10-13 | 2007-10-04 | Pegylated pth as pth receptor modulators and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010506844A JP2010506844A (ja) | 2010-03-04 |
| JP2010506844A5 true JP2010506844A5 (enExample) | 2010-10-07 |
| JP5200027B2 JP5200027B2 (ja) | 2013-05-15 |
Family
ID=42828673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009532504A Expired - Fee Related JP5200027B2 (ja) | 2006-10-13 | 2007-10-04 | Ｐｔｈ受容体モジュレーターとしてのペグ化ｐｔｈおよびその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7820179B2 (enExample) |
| EP (1) | EP2084183B1 (enExample) |
| JP (1) | JP5200027B2 (enExample) |
| KR (1) | KR101108354B1 (enExample) |
| CN (1) | CN101522709B (enExample) |
| AT (1) | ATE469173T1 (enExample) |
| AU (1) | AU2007313001B2 (enExample) |
| BR (1) | BRPI0719885B8 (enExample) |
| CA (1) | CA2672907C (enExample) |
| DK (1) | DK2084183T3 (enExample) |
| EA (1) | EA014696B1 (enExample) |
| MX (1) | MX2009003740A (enExample) |
| NO (1) | NO341986B1 (enExample) |
| PL (1) | PL2084183T3 (enExample) |
| SI (1) | SI2084183T1 (enExample) |
| WO (1) | WO2008048784A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9585934B2 (en) | 2014-10-22 | 2017-03-07 | Extend Biosciences, Inc. | Therapeutic vitamin D conjugates |
| SI3423103T1 (sl) * | 2016-03-01 | 2024-12-31 | Ascendis Pharma Bone Diseases A/S | Predzdravila PTH |
| JP7039574B2 (ja) | 2016-09-29 | 2022-03-22 | アセンディス ファーマ ボーン ディジージズ エー／エス | 放出制御ｐｔｈ化合物の漸増用量設定 |
| KR102611820B1 (ko) | 2016-09-29 | 2023-12-07 | 아센디스 파마 본 디지즈 에이/에스 | 낮은 피크 대 트로프 비를 가진 pth 화합물 |
| HUE063235T2 (hu) | 2016-09-29 | 2024-01-28 | Ascendis Pharma Bone Diseases As | Adagolási rendszer szabályozott leadású PTH vegyülethez |
| EP3796941A4 (en) | 2018-05-30 | 2022-12-28 | Purdue Research Foundation | Targeting anabolic drugs for accelerated fracture repair |
| AU2020221491B2 (en) | 2019-02-11 | 2025-02-27 | Ascendis Pharma Bone Diseases A/S | Liquid pharmaceutical formulations of PTH conjugates |
| US12233115B2 (en) | 2022-09-30 | 2025-02-25 | Extend Biosciences, Inc. | Long-acting parathyroid hormone |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| FR2550204B1 (fr) | 1983-08-05 | 1987-11-13 | Toyo Jozo Kk | Derives peptidiques de (nle8,nle1b, tyr34)-h-pth |
| JPS6360940A (ja) | 1986-09-01 | 1988-03-17 | Toyo Jozo Co Ltd | 白内障の予防または治療剤 |
| US4771124A (en) | 1987-05-26 | 1988-09-13 | Merck & Co., Inc. | Parathyroid hormone antagonists with simplified synthetic methodology |
| EP0293158A3 (en) | 1987-05-26 | 1990-05-09 | Merck & Co. Inc. | Parathyroid hormone antagonists |
| JPH0532696A (ja) | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
| JPH05271279A (ja) | 1991-08-07 | 1993-10-19 | Takeda Chem Ind Ltd | ヒト副甲状腺ホルモンムテインおよびその製造法 |
| US5814603A (en) | 1992-06-12 | 1998-09-29 | Affymax Technologies N.V. | Compounds with PTH activity |
| US5589452A (en) | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
| AU672790B2 (en) | 1992-07-15 | 1996-10-17 | Novartis Ag | Variants of parathyroid hormone and its fragments |
| US5556940A (en) | 1994-06-20 | 1996-09-17 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
| US6110892A (en) | 1994-06-20 | 2000-08-29 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
| US5747456A (en) | 1994-12-19 | 1998-05-05 | Beth Israel Deaconess Medical Center | Continuous low-dose administration of parathyroid hormone or its agonist |
| US5717062A (en) | 1995-06-07 | 1998-02-10 | Beth Israel Hospital Association | Cyclic analogs of PTH and PTHrP |
| CA2178894A1 (en) | 1995-06-15 | 1996-12-16 | Tsunehiko Fukuda | Parathyroid hormone derivatives and their use |
| US6544949B1 (en) | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
| US5723577A (en) | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
| US5955574A (en) | 1995-07-13 | 1999-09-21 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. | Analogs of parathyroid hormone |
| PT915911E (pt) | 1996-08-02 | 2004-03-31 | Ca Nat Research Council | Analogos da hormona paratiroideia para o tratamento de osteoporose |
| EA002819B1 (ru) | 1997-05-14 | 2002-10-31 | Авентис Фармасьютикалз Продактс Инк. | Циклическое пептидное соединение и его применение, бициклопептидное соединение, пептидное соединение и его применение, фармацевтическая композиция |
| CA2306344A1 (en) * | 1997-10-14 | 1999-04-22 | Masahiko Sato | Method of building and maintaining bone |
| AU757658B2 (en) | 1998-03-09 | 2003-02-27 | Zealand Pharma A/S | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
| JP2002511483A (ja) | 1998-04-15 | 2002-04-16 | アヴェンティス ファーマシューティカルズ プロダクツ インコーポレイテッド | 樹脂結合環状ペプチドの製造方法 |
| AU3673699A (en) | 1998-05-05 | 1999-11-23 | Beth Israel Deaconess Medical Center | Pth2 receptor selective compounds |
| US6316410B1 (en) | 1999-09-22 | 2001-11-13 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
| US7022815B1 (en) | 1999-09-29 | 2006-04-04 | The General Hospital Corporation | Polypeptide derivatives of parathyroid hormone (PTH) |
| AU7734800A (en) | 1999-09-29 | 2001-04-30 | General Hospital Corporation, The | Polypeptide derivatives of parathyroid hormone (pth) |
| US20050124537A1 (en) | 2000-04-27 | 2005-06-09 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| US6756480B2 (en) | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
| US7572765B2 (en) | 2001-07-23 | 2009-08-11 | The General Hospital Corporation | Conformationally constrained parathyroid hormone (PTH) analogs |
| US20050148763A1 (en) | 2002-02-01 | 2005-07-07 | Chugai Seiyaku Kabushiki Kaisha | Peg-binding pth or peg-binding pth derivative |
| US7799757B2 (en) | 2002-06-13 | 2010-09-21 | Michael Chorev | Analogs of parathyroid hormone and PTH-related protein as bone anabolic agents |
| TW533925U (en) | 2002-09-26 | 2003-05-21 | Lee Yeong Ind Co Ltd | Improvement of speed-changing transmission mechanism for cutting tools of drill sharpening machine |
| AU2002359391A1 (en) | 2002-11-01 | 2004-07-29 | Amgen, Inc. | Modulators of receptors for parathyrois hormone and parathyroid hormone-related protein |
| ATE444984T1 (de) | 2002-12-31 | 2009-10-15 | Nektar Therapeutics Al Corp | Hydrolysestabile maleimidendgruppen-enthaltende polymere |
| US20060105988A1 (en) * | 2003-03-25 | 2006-05-18 | Tatsuo Shimizu | Antipruritic composition for external use on skin |
| US20040220094A1 (en) | 2003-05-01 | 2004-11-04 | Skinner Keith K. | Inverse agonist and agonist peptides that stimulate/inhibit hair growth |
| WO2005072277A2 (en) | 2004-01-21 | 2005-08-11 | Unigene Laboratories Inc. | Amidated parathyroid hormone fragments and uses thereof |
-
2007
- 2007-10-04 SI SI200730296T patent/SI2084183T1/sl unknown
- 2007-10-04 EP EP07843791A patent/EP2084183B1/en active Active
- 2007-10-04 BR BRPI0719885A patent/BRPI0719885B8/pt not_active IP Right Cessation
- 2007-10-04 CN CN2007800382095A patent/CN101522709B/zh not_active Expired - Fee Related
- 2007-10-04 EA EA200970376A patent/EA014696B1/ru not_active IP Right Cessation
- 2007-10-04 AU AU2007313001A patent/AU2007313001B2/en not_active Ceased
- 2007-10-04 DK DK07843791.0T patent/DK2084183T3/da active
- 2007-10-04 AT AT07843791T patent/ATE469173T1/de active
- 2007-10-04 MX MX2009003740A patent/MX2009003740A/es active IP Right Grant
- 2007-10-04 KR KR1020097007424A patent/KR101108354B1/ko not_active Expired - Fee Related
- 2007-10-04 WO PCT/US2007/080367 patent/WO2008048784A1/en not_active Ceased
- 2007-10-04 US US12/440,619 patent/US7820179B2/en not_active Expired - Fee Related
- 2007-10-04 JP JP2009532504A patent/JP5200027B2/ja not_active Expired - Fee Related
- 2007-10-04 PL PL07843791T patent/PL2084183T3/pl unknown
- 2007-10-04 CA CA2672907A patent/CA2672907C/en not_active Expired - Fee Related
-
2009
- 2009-04-28 NO NO20091691A patent/NO341986B1/no not_active IP Right Cessation
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