JP2010505518A5 - - Google Patents

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Publication number
JP2010505518A5
JP2010505518A5 JP2009531436A JP2009531436A JP2010505518A5 JP 2010505518 A5 JP2010505518 A5 JP 2010505518A5 JP 2009531436 A JP2009531436 A JP 2009531436A JP 2009531436 A JP2009531436 A JP 2009531436A JP 2010505518 A5 JP2010505518 A5 JP 2010505518A5
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JP
Japan
Prior art keywords
applicator
electrode
needle
applicators
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009531436A
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English (en)
Japanese (ja)
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JP2010505518A (ja
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Publication date
Priority claimed from US11/538,249 external-priority patent/US20070185432A1/en
Application filed filed Critical
Publication of JP2010505518A publication Critical patent/JP2010505518A/ja
Publication of JP2010505518A5 publication Critical patent/JP2010505518A5/ja
Pending legal-status Critical Current

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JP2009531436A 2006-10-03 2007-10-03 メトトレキサートを送達する動電システムおよび方法 Pending JP2010505518A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/538,249 US20070185432A1 (en) 2005-09-19 2006-10-03 Electrokinetic system and method for delivering methotrexate
PCT/US2007/021226 WO2008042404A2 (en) 2006-10-03 2007-10-03 Electrokinetic system and method for delivering methotrexate

Publications (2)

Publication Number Publication Date
JP2010505518A JP2010505518A (ja) 2010-02-25
JP2010505518A5 true JP2010505518A5 (enExample) 2011-12-08

Family

ID=39269032

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009531436A Pending JP2010505518A (ja) 2006-10-03 2007-10-03 メトトレキサートを送達する動電システムおよび方法

Country Status (4)

Country Link
US (1) US20070185432A1 (enExample)
EP (1) EP2079515A2 (enExample)
JP (1) JP2010505518A (enExample)
WO (1) WO2008042404A2 (enExample)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
AU2003209095A1 (en) 2002-02-11 2003-09-04 Antares Pharma, Inc. Intradermal injector
US8571648B2 (en) * 2004-05-07 2013-10-29 Aesthera Apparatus and method to apply substances to tissue
US7842029B2 (en) * 2004-05-07 2010-11-30 Aesthera Apparatus and method having a cooling material and reduced pressure to treat biological external tissue
DK1850892T4 (da) 2005-01-24 2023-06-06 Antares Pharma Inc Forfyldt nål-assisteret sprøjtejetinjektor
US20090264809A1 (en) * 2006-04-10 2009-10-22 The Regents Of The University Of California Method and apparatus of low strengh electric field network-mediated delnery of drug, gene, sirna, shrn, protein, peptide, antibody or other biomedical and therapeutic molecules and reagents in skin, soft tissue, joints and bone
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US20090012434A1 (en) * 2007-07-03 2009-01-08 Anderson Robert S Apparatus, method, and system to treat a volume of skin
US20090069795A1 (en) * 2007-09-10 2009-03-12 Anderson Robert S Apparatus and method for selective treatment of tissue
EP2197541A4 (en) * 2007-09-20 2011-06-01 Nitric Biotherapeutics Inc METHOD FOR REINFORCING IOPOPHORETIC DELIVERY OF A PEPTIDE
US20090093864A1 (en) * 2007-10-08 2009-04-09 Anderson Robert S Methods and devices for applying energy to tissue
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
US8814834B2 (en) 2008-03-10 2014-08-26 Antares Pharma, Inc. Injector safety device
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
CN105999538A (zh) * 2008-11-18 2016-10-12 3M创新有限公司 空心微针阵列和方法
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
EP2408372B1 (en) 2009-03-02 2019-01-09 Seventh Sense Biosystems, Inc. Devices associated with blood sampling
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
EP2408493B1 (en) 2009-03-20 2024-07-24 Antares Pharma, Inc. Hazardous agent injection system
CN101829396B (zh) * 2009-03-27 2013-01-30 清华大学 微针阵列芯片及利用其的经皮给药贴剂及其制备方法
FI20095433A0 (fi) 2009-04-20 2009-04-20 Valtion Teknillinen Mikroneula
US10159825B2 (en) * 2009-09-17 2018-12-25 Zipline Medical, Inc. Rapid closing surgical closure device
US10245421B2 (en) 2010-04-28 2019-04-02 Sorrento Therapeutics, Inc. Nanopatterned medical device with enhanced cellular interaction
JP6030551B2 (ja) 2010-06-14 2016-11-24 ジップライン メディカル， インコーポレイテッド 瘢痕形成を阻止する方法および装置
ES2561824T3 (es) 2010-07-16 2016-03-01 Seventh Sense Biosystems, Inc. Ambiente a baja presión para dispositivos de transferencia de fluidos
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
EP2954916A3 (en) * 2010-08-13 2016-04-20 Seventh Sense Biosystems, Inc. Clinical and/or consumer techniques and devices
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
ES2565805T3 (es) 2010-11-09 2016-04-07 Seventh Sense Biosystems, Inc. Sistemas e interfaces para el muestreo de sangre
WO2012135805A2 (en) 2011-03-31 2012-10-04 modeRNA Therapeutics Delivery and formulation of engineered nucleic acids
AU2012249683A1 (en) 2011-04-29 2013-11-14 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
EP3473296B1 (en) * 2011-06-28 2020-08-05 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
AU2015203882C1 (en) * 2011-06-28 2017-09-21 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9561034B2 (en) 2011-11-01 2017-02-07 Zipline Medical, Inc. Surgical incision and closure apparatus
US10123800B2 (en) 2011-11-01 2018-11-13 Zipline Medical, Inc. Surgical incision and closure apparatus with integrated force distribution
US10123801B2 (en) 2011-11-01 2018-11-13 Zipline Medical, Inc. Means to prevent wound dressings from adhering to closure device
US12171432B2 (en) 2011-11-01 2024-12-24 Zipline Medical, Inc. Closure apparatuses and methods for ulcers and irregular skin defects
KR20140102759A (ko) 2011-12-16 2014-08-22 모더나 세라퓨틱스, 인코포레이티드 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
KR20150003179A (ko) 2012-03-06 2015-01-08 안타레스 팔마, 인코퍼레이티드 분리력 특징을 가진 사전충전형 주사기
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
WO2013169804A1 (en) 2012-05-07 2013-11-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
CA2892529C (en) 2012-11-26 2023-04-25 Moderna Therapeutics, Inc. Terminally modified rna
CA2932540A1 (en) * 2012-12-14 2014-06-19 The Trustees Of Columbia University In The City Of New York System and method to locally deliver therapeutic agent to inner ear
HK1217215A1 (zh) 2013-01-17 2016-12-30 Modernatx, Inc. 用於改变细胞表型的信号传感器多核苷酸
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
EP3572108A1 (en) 2013-03-11 2019-11-27 Antares Pharma, Inc. Dosage injector with pinion system
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CN105873525A (zh) 2014-01-05 2016-08-17 奇普林医药公司 仪表化伤口闭合装置
KR102135495B1 (ko) * 2014-02-27 2020-07-17 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들·시트
JP6392162B2 (ja) * 2014-05-26 2018-09-19 株式会社スズキプレシオン 注入針装置及び注入器具セット
CA2991689C (en) * 2014-07-24 2023-06-20 Sasi Solomon Device and methods for delivery of stimulation to a body tissue
JP6198694B2 (ja) * 2014-08-07 2017-09-20 典雄 宮城 注射針
WO2018081795A1 (en) 2016-10-31 2018-05-03 Zipline Medical, Inc. Systems and methods for monitoring physical therapy of the knee and other joints
JP2018086071A (ja) * 2016-11-28 2018-06-07 株式会社リコー 経皮吸収デバイス及び経皮吸収パッチ
WO2018119090A1 (en) * 2016-12-22 2018-06-28 Ohio State Innovation Foundation Interpentrating microstructures for nanochannel-based cargo delivery
US12415058B2 (en) 2016-12-22 2025-09-16 Ohio State Innovation Foundation Interpenetrating microstructures for nanochannel-based sampling and/or cargo delivery
CA3073215A1 (en) * 2017-10-06 2019-04-11 Medtronic Xomed, Inc. Pledget stimulation and recording electrode assemblies
GB2574074B (en) 2018-07-27 2020-05-20 Mclaren Applied Tech Ltd Time synchronisation
CN111544593A (zh) * 2019-03-26 2020-08-18 华中科技大学同济医学院附属协和医院 一种载抗银屑病系统药物的微针贴片及其制备方法
GB2588236B (en) 2019-10-18 2024-03-20 Mclaren Applied Ltd Gyroscope bias estimation
CN116570829A (zh) * 2023-05-25 2023-08-11 东华大学 一种透皮给药贴片、其制备方法及应用

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4378806A (en) * 1980-08-12 1983-04-05 Henley Cohn Julian L Gapped resonant microwave apparatus for producing hyperthermia therapy of tumors
US4543088A (en) * 1983-11-07 1985-09-24 American Hospital Supply Corporation Self-sealing subcutaneous injection site
US5163899A (en) * 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5078700A (en) * 1990-03-19 1992-01-07 Becton, Dickinson And Company Liquid crystalline catheter
US5160316A (en) * 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5331979A (en) * 1992-07-27 1994-07-26 Henley Julian L Iontophoretic cigarette substitute
US5534023A (en) * 1992-12-29 1996-07-09 Henley; Julian L. Fluid filled prosthesis excluding gas-filled beads
US5545143A (en) * 1993-01-21 1996-08-13 T. S. I. Medical Device for subcutaneous medication delivery
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5415629A (en) * 1993-09-15 1995-05-16 Henley; Julian L. Programmable apparatus for the transdermal delivery of drugs and method
KR100370728B1 (ko) * 1994-10-27 2003-04-07 실리콘 밸리 그룹, 인크. 기판을균일하게코팅하는방법및장치
US5908401A (en) * 1996-05-08 1999-06-01 The Aps Organization, Llp Method for iontophoretic delivery of antiviral agents
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
US6385487B1 (en) * 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
DE69719761T2 (de) * 1996-06-18 2003-12-18 Alza Corp., Palo Alto Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US6078842A (en) * 1997-04-08 2000-06-20 Elan Corporation, Plc Electrode and iontophoretic device and method
EP1005296B8 (en) * 1997-06-05 2005-06-08 Adiana, Inc. Apparatus for tubal occlusion
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
GB9815819D0 (en) * 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6328735B1 (en) * 1998-10-30 2001-12-11 E.P., Limited Thermal ablation system
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6597946B2 (en) * 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
WO2000044438A1 (en) * 1999-01-28 2000-08-03 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
DE60018726T2 (de) * 1999-04-16 2006-04-13 Johnson & Johnson Consumer Companies, Inc. Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6511463B1 (en) * 1999-11-18 2003-01-28 Jds Uniphase Corporation Methods of fabricating microneedle arrays using sacrificial molds
US6565532B1 (en) * 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
US6989156B2 (en) * 2001-04-23 2006-01-24 Nucryst Pharmaceuticals Corp. Therapeutic treatments using the direct application of antimicrobial metal compositions
US6690959B2 (en) * 2000-09-01 2004-02-10 Medtronic, Inc. Skin-mounted electrodes with nano spikes
US6591133B1 (en) * 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
US20020099356A1 (en) * 2001-01-19 2002-07-25 Unger Evan C. Transmembrane transport apparatus and method
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US6689100B2 (en) * 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US7643874B2 (en) * 2001-10-24 2010-01-05 Power Paper Ltd. Dermal patch
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US20030144625A1 (en) * 2002-01-28 2003-07-31 Garry Sherman Method and apparatus for the treatment of infections of the nail matrix and nail plate
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7115881B2 (en) * 2002-06-04 2006-10-03 Mario Rabinowitz Positioning and motion control by electrons, ions, and neutrals in electric fields
US8062573B2 (en) * 2002-09-16 2011-11-22 Theraject, Inc. Solid micro-perforators and methods of use
IL152271A (en) * 2002-10-13 2006-04-10 Meir Hefetz Structures of micro needles and manufacturing methods
US6923791B2 (en) * 2003-03-31 2005-08-02 Sterling Medivations, Inc. Infusion device having offset flow path
EP1633431B1 (en) * 2003-06-02 2008-11-12 Power Paper Ltd. Kit, device and method for controlled delivery of oxidizing agent into the skin
US7647100B2 (en) * 2003-07-14 2010-01-12 Power Paper Ltd. Method, apparatus, and kit for onychomycosis treatment
EP1662987B1 (en) * 2003-09-11 2011-11-09 Theranos, Inc. Medical device for analyte monitoring and drug delivery
US20050123565A1 (en) * 2003-10-31 2005-06-09 Janardhanan Subramony System and method for transdermal vaccine delivery
US6834206B1 (en) * 2003-12-23 2004-12-21 Sono-Therapy Institute, Inc. Method for the electrical stimulation of human tissue to encourage hair growth
US7315758B2 (en) * 2004-06-03 2008-01-01 Lynntech, Inc. Transdermal delivery of therapeutic agent
US20060275228A1 (en) * 2005-05-09 2006-12-07 Bissett Donald L Skin care compositions containing idebenone
US20060275237A1 (en) * 2005-05-09 2006-12-07 Bissett Donald L Skin care compositions containing idebenone
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods

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