JP2010285434A5 - - Google Patents
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- JP2010285434A5 JP2010285434A5 JP2010142292A JP2010142292A JP2010285434A5 JP 2010285434 A5 JP2010285434 A5 JP 2010285434A5 JP 2010142292 A JP2010142292 A JP 2010142292A JP 2010142292 A JP2010142292 A JP 2010142292A JP 2010285434 A5 JP2010285434 A5 JP 2010285434A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- use according
- retinopathy
- vascular
- mammal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Claims (16)
- 哺乳動物の網膜の新生血管形成を増強する組成物を製造するための、少なくとも約50%の細胞が細胞マーカーCD31及びc−kitを含む内皮前駆細胞を含む、単離された、哺乳動物の骨髄由来である系統陰性の造血幹細胞集団の使用。
- 前記哺乳動物がマウスである、請求項1に記載の使用。
- 前記哺乳動物がヒトである、請求項1に記載の使用。
- 眼疾患を治療するための組成物を製造するための、患者の骨髄に由来する内皮前駆細胞を含む系統陰性の造血幹細胞集団の使用。
- 前記疾患が網膜変性疾患である、請求項4に記載の使用。
- 前記疾患が網膜血管変性疾患である、請求項4に記載の使用。
- 前記疾患が虚血性網膜症である、請求項4に記載の使用。
- 前記疾患が血管出血である、請求項4に記載の使用。
- 前記疾患が血管漏出である、請求項4に記載の使用。
- 前記疾患が脈絡膜症である、請求項4に記載の使用。
- 前記疾患が加齢黄斑変性である、請求項4に記載の使用。
- 前記疾患が糖尿病性網膜症である、請求項4に記載の使用。
- 前記疾患が推定眼ヒストプラスマ症である、請求項4に記載の使用。
- 前記疾患が未熟児網膜症である、請求項4に記載の使用。
- 前記疾患が鎌状赤血球貧血である、請求項4に記載の使用。
- 前記疾患が色素性網膜炎である、請求項4に記載の使用。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39852202P | 2002-07-25 | 2002-07-25 | |
US60/398,522 | 2002-07-25 | ||
US46705103P | 2003-05-02 | 2003-05-02 | |
US60/467,051 | 2003-05-02 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005505648A Division JP2005538742A (ja) | 2002-07-25 | 2003-07-25 | 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2010285434A JP2010285434A (ja) | 2010-12-24 |
JP2010285434A5 true JP2010285434A5 (ja) | 2011-10-13 |
JP5385219B2 JP5385219B2 (ja) | 2014-01-08 |
Family
ID=31191212
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005505648A Pending JP2005538742A (ja) | 2002-07-25 | 2003-07-25 | 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 |
JP2010142292A Expired - Fee Related JP5385219B2 (ja) | 2002-07-25 | 2010-06-23 | 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005505648A Pending JP2005538742A (ja) | 2002-07-25 | 2003-07-25 | 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 |
Country Status (17)
Country | Link |
---|---|
US (2) | US7153501B2 (ja) |
EP (1) | EP1542536B1 (ja) |
JP (2) | JP2005538742A (ja) |
KR (2) | KR101095287B1 (ja) |
CN (1) | CN1307300C (ja) |
AT (1) | ATE536405T1 (ja) |
AU (1) | AU2003259687B2 (ja) |
BR (1) | BR0312920A (ja) |
CA (1) | CA2493122C (ja) |
DK (1) | DK1542536T3 (ja) |
ES (1) | ES2376866T3 (ja) |
MX (1) | MXPA05000972A (ja) |
PL (1) | PL216193B1 (ja) |
PT (1) | PT1542536E (ja) |
RU (1) | RU2331669C2 (ja) |
WO (2) | WO2004010959A2 (ja) |
ZA (1) | ZA200500682B (ja) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006031467A2 (en) * | 2002-07-25 | 2006-03-23 | The Scripps Research Institute | Isolated lineage negative hematopoietic stem cells and methods of treatment therewith |
US20060104963A1 (en) * | 2002-07-25 | 2006-05-18 | The Scripps Research Institute | Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells |
US20060104962A1 (en) * | 2002-07-25 | 2006-05-18 | The Scripps Research Institute | Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
CA2524063C (en) * | 2003-05-02 | 2015-02-17 | The Scripps Research Institute | Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
US8088585B2 (en) * | 2003-10-31 | 2012-01-03 | Children's Medical Center Corporation | Methods for purifying hematopoietic stem cells |
US8282921B2 (en) | 2004-08-02 | 2012-10-09 | Paul Glidden | tRNA synthetase fragments |
JP2008509678A (ja) * | 2004-08-13 | 2008-04-03 | メドトロニック・インコーポレーテッド | 内皮前駆細胞サブセットの単離とそれらの使用方法 |
JP2008512376A (ja) * | 2004-09-03 | 2008-04-24 | ザ・スクリプス・リサーチ・インステイチユート | 単離された系統陰性造血幹細胞及びこれを用いた治療方法 |
DE102004055615A1 (de) * | 2004-11-16 | 2006-05-18 | Universitätsklinikum Hamburg-Eppendorf | In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung |
US20070231306A1 (en) * | 2005-02-24 | 2007-10-04 | The Scripps Research Institute | Isolated myeloid-like cell populations and methods of treatment therewith |
US7931891B2 (en) * | 2005-02-24 | 2011-04-26 | The Scripps Research Institute | Isolated myeloid-like bone marrow cell populations and methods of treatment therewith |
EP1853113A4 (en) * | 2005-02-24 | 2011-03-30 | Scripps Research Inst | ISCHEMIC RETINIC TISSUE REVASCULARIZATION AND SCREENING METHOD THEREOF |
DK1935976T3 (da) * | 2005-02-24 | 2012-04-10 | Scripps Research Inst | Transficerede myeloid-lignende celler til behandling af retinopati ved for tidlig fødsel og dermed relaterede sygdomme |
JP4734636B2 (ja) * | 2005-11-02 | 2011-07-27 | 国立大学法人 鹿児島大学 | 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法 |
PT1951864E (pt) | 2005-11-07 | 2014-08-27 | Amorcyte Inc | Composições e métodos de reparação de lesões vasculares |
US8637005B2 (en) | 2005-11-07 | 2014-01-28 | Amorcyte, Inc. | Compositions and methods of vascular injury repair |
US20110076255A1 (en) | 2005-11-07 | 2011-03-31 | Pecora Andrew L | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
CA2644922C (en) * | 2006-03-07 | 2019-07-23 | Geeta Shroff | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
KR100757265B1 (ko) * | 2006-04-27 | 2007-09-10 | (주) 차바이오텍 | 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물 |
AU2007272313B2 (en) * | 2006-07-12 | 2013-11-21 | Mesoblast, Inc. | Treatment of excessive neovascularization |
CN103230414A (zh) * | 2006-11-07 | 2013-08-07 | 夏尔再生医学公司 | 用于治疗和控制血管生成介导的疾病的材料和方法 |
US20100098675A1 (en) * | 2008-05-30 | 2010-04-22 | Nikolai Tankovich | Methods for reducing the side effects of ophthalmic laser surgery |
RU2535966C2 (ru) * | 2008-09-12 | 2014-12-20 | Криопрашис Криобиоложия Лтда. | Клеточная терапия ишемической ткани |
CA2743255C (en) | 2008-12-03 | 2014-02-18 | Andrew Pecora | Infarct area perfusion-improving compositions and methods of vascular injury repair |
WO2012005763A1 (en) | 2010-07-06 | 2012-01-12 | The Scripps Research Institute | Use of myeloid-like progenitor cell populations to treat tumors |
US9265813B2 (en) | 2011-10-27 | 2016-02-23 | Wellstat Ophthalmics Corporation | Vectors encoding rod-derived cone viability factor |
CA2870466A1 (en) * | 2012-04-16 | 2013-10-24 | The Regents Of The University Of California | Ocular therapeutics using embryonic stem cell microvesicles |
CA2882802C (en) * | 2012-08-24 | 2021-07-06 | Riken | Method for producing retinal pigment epithelial cell sheet |
WO2020172854A1 (en) * | 2019-02-28 | 2020-09-03 | Shenzhen University | Use of endothelial progenitor cells (epcs) in rejuvenating microvasculature, preventing aging and treating age-related diseases |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6908763B1 (en) * | 1997-08-22 | 2005-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian common lymphoid progenitor cell |
WO1999055837A2 (en) * | 1998-04-28 | 1999-11-04 | Nycomed Imaging As | Improvements in or relating to separation processes |
US6767737B1 (en) * | 1998-08-31 | 2004-07-27 | New York University | Stem cells bearing an FGF receptor on the cell surface |
US6780627B1 (en) * | 2000-01-31 | 2004-08-24 | Millennium Pharmaceuticals, Inc. | 22438, 23553, 25278, and 26212 novel human sulfatases |
US20030017564A1 (en) * | 2001-02-23 | 2003-01-23 | Paul Schimmel | Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiogenesis |
US20020061587A1 (en) * | 2000-07-31 | 2002-05-23 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
WO2003080116A1 (en) * | 2002-03-21 | 2003-10-02 | University Of Florida | Modulating angiogenesis |
WO2004005531A2 (en) * | 2002-07-05 | 2004-01-15 | Roger Williams Medical Center | Targeting and tracking of cells to specific organs and tissues in vivo |
-
2003
- 2003-07-25 DK DK03772195.8T patent/DK1542536T3/da active
- 2003-07-25 JP JP2005505648A patent/JP2005538742A/ja active Pending
- 2003-07-25 WO PCT/US2003/024839 patent/WO2004010959A2/en active Search and Examination
- 2003-07-25 ES ES03772195T patent/ES2376866T3/es not_active Expired - Lifetime
- 2003-07-25 CN CNB038177358A patent/CN1307300C/zh not_active Expired - Fee Related
- 2003-07-25 BR BRPI0312920-9A patent/BR0312920A/pt not_active IP Right Cessation
- 2003-07-25 MX MXPA05000972A patent/MXPA05000972A/es active IP Right Grant
- 2003-07-25 CA CA2493122A patent/CA2493122C/en not_active Expired - Fee Related
- 2003-07-25 AT AT03772195T patent/ATE536405T1/de active
- 2003-07-25 US US10/628,783 patent/US7153501B2/en not_active Expired - Fee Related
- 2003-07-25 KR KR1020057001388A patent/KR101095287B1/ko not_active IP Right Cessation
- 2003-07-25 AU AU2003259687A patent/AU2003259687B2/en not_active Ceased
- 2003-07-25 EP EP03772195A patent/EP1542536B1/en not_active Expired - Lifetime
- 2003-07-25 PT PT03772195T patent/PT1542536E/pt unknown
- 2003-07-25 PL PL374868A patent/PL216193B1/pl unknown
- 2003-07-25 KR KR1020117020059A patent/KR20110102961A/ko not_active Application Discontinuation
- 2003-07-25 RU RU2005105065/13A patent/RU2331669C2/ru not_active IP Right Cessation
-
2004
- 2004-04-28 WO PCT/US2004/012989 patent/WO2004098499A2/en active Application Filing
-
2005
- 2005-01-24 ZA ZA200500682A patent/ZA200500682B/xx unknown
-
2006
- 2006-12-20 US US11/643,571 patent/US20070116685A1/en not_active Abandoned
-
2010
- 2010-06-23 JP JP2010142292A patent/JP5385219B2/ja not_active Expired - Fee Related
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