JP2010285434A5 - - Google Patents

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Publication number
JP2010285434A5
JP2010285434A5 JP2010142292A JP2010142292A JP2010285434A5 JP 2010285434 A5 JP2010285434 A5 JP 2010285434A5 JP 2010142292 A JP2010142292 A JP 2010142292A JP 2010142292 A JP2010142292 A JP 2010142292A JP 2010285434 A5 JP2010285434 A5 JP 2010285434A5
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JP
Japan
Prior art keywords
disease
use according
retinopathy
vascular
mammal
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JP2010142292A
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English (en)
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JP5385219B2 (ja
JP2010285434A (ja
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Publication of JP2010285434A publication Critical patent/JP2010285434A/ja
Publication of JP2010285434A5 publication Critical patent/JP2010285434A5/ja
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Publication of JP5385219B2 publication Critical patent/JP5385219B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Claims (16)

  1. 哺乳動物の網膜の新生血管形成を増強する組成物を製造するための、少なくとも約50%の細胞が細胞マーカーCD31及びc−kitを含む内皮前駆細胞を含む、単離された、哺乳動物の骨髄由来である系統陰性の造血幹細胞集団の使用。
  2. 前記哺乳動物がマウスである、請求項1に記載の使用。
  3. 前記哺乳動物がヒトである、請求項1に記載の使用。
  4. 眼疾患を治療するための組成物を製造するための、患者の骨髄に由来する内皮前駆細胞を含む系統陰性の造血幹細胞集団の使用。
  5. 前記疾患が網膜変性疾患である、請求項4に記載の使用。
  6. 前記疾患が網膜血管変性疾患である、請求項4に記載の使用。
  7. 前記疾患が虚血性網膜症である、請求項4に記載の使用。
  8. 前記疾患が血管出血である、請求項4に記載の使用。
  9. 前記疾患が血管漏出である、請求項4に記載の使用。
  10. 前記疾患が脈絡膜症である、請求項4に記載の使用。
  11. 前記疾患が加齢黄斑変性である、請求項4に記載の使用。
  12. 前記疾患が糖尿病性網膜症である、請求項4に記載の使用。
  13. 前記疾患が推定眼ヒストプラスマ症である、請求項4に記載の使用。
  14. 前記疾患が未熟児網膜症である、請求項4に記載の使用。
  15. 前記疾患が鎌状赤血球貧血である、請求項4に記載の使用。
  16. 前記疾患が色素性網膜炎である、請求項4に記載の使用。
JP2010142292A 2002-07-25 2010-06-23 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 Expired - Fee Related JP5385219B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39852202P 2002-07-25 2002-07-25
US60/398,522 2002-07-25
US46705103P 2003-05-02 2003-05-02
US60/467,051 2003-05-02

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2005505648A Division JP2005538742A (ja) 2002-07-25 2003-07-25 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法

Publications (3)

Publication Number Publication Date
JP2010285434A JP2010285434A (ja) 2010-12-24
JP2010285434A5 true JP2010285434A5 (ja) 2011-10-13
JP5385219B2 JP5385219B2 (ja) 2014-01-08

Family

ID=31191212

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2005505648A Pending JP2005538742A (ja) 2002-07-25 2003-07-25 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法
JP2010142292A Expired - Fee Related JP5385219B2 (ja) 2002-07-25 2010-06-23 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2005505648A Pending JP2005538742A (ja) 2002-07-25 2003-07-25 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法

Country Status (17)

Country Link
US (2) US7153501B2 (ja)
EP (1) EP1542536B1 (ja)
JP (2) JP2005538742A (ja)
KR (2) KR101095287B1 (ja)
CN (1) CN1307300C (ja)
AT (1) ATE536405T1 (ja)
AU (1) AU2003259687B2 (ja)
BR (1) BR0312920A (ja)
CA (1) CA2493122C (ja)
DK (1) DK1542536T3 (ja)
ES (1) ES2376866T3 (ja)
MX (1) MXPA05000972A (ja)
PL (1) PL216193B1 (ja)
PT (1) PT1542536E (ja)
RU (1) RU2331669C2 (ja)
WO (2) WO2004010959A2 (ja)
ZA (1) ZA200500682B (ja)

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WO2006031467A2 (en) * 2002-07-25 2006-03-23 The Scripps Research Institute Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
US20060104963A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells
US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
CA2524063C (en) * 2003-05-02 2015-02-17 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
US8088585B2 (en) * 2003-10-31 2012-01-03 Children's Medical Center Corporation Methods for purifying hematopoietic stem cells
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
JP2008509678A (ja) * 2004-08-13 2008-04-03 メドトロニック・インコーポレーテッド 内皮前駆細胞サブセットの単離とそれらの使用方法
JP2008512376A (ja) * 2004-09-03 2008-04-24 ザ・スクリプス・リサーチ・インステイチユート 単離された系統陰性造血幹細胞及びこれを用いた治療方法
DE102004055615A1 (de) * 2004-11-16 2006-05-18 Universitätsklinikum Hamburg-Eppendorf In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung
US20070231306A1 (en) * 2005-02-24 2007-10-04 The Scripps Research Institute Isolated myeloid-like cell populations and methods of treatment therewith
US7931891B2 (en) * 2005-02-24 2011-04-26 The Scripps Research Institute Isolated myeloid-like bone marrow cell populations and methods of treatment therewith
EP1853113A4 (en) * 2005-02-24 2011-03-30 Scripps Research Inst ISCHEMIC RETINIC TISSUE REVASCULARIZATION AND SCREENING METHOD THEREOF
DK1935976T3 (da) * 2005-02-24 2012-04-10 Scripps Research Inst Transficerede myeloid-lignende celler til behandling af retinopati ved for tidlig fødsel og dermed relaterede sygdomme
JP4734636B2 (ja) * 2005-11-02 2011-07-27 国立大学法人 鹿児島大学 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法
PT1951864E (pt) 2005-11-07 2014-08-27 Amorcyte Inc Composições e métodos de reparação de lesões vasculares
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
CA2644922C (en) * 2006-03-07 2019-07-23 Geeta Shroff Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
KR100757265B1 (ko) * 2006-04-27 2007-09-10 (주) 차바이오텍 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물
AU2007272313B2 (en) * 2006-07-12 2013-11-21 Mesoblast, Inc. Treatment of excessive neovascularization
CN103230414A (zh) * 2006-11-07 2013-08-07 夏尔再生医学公司 用于治疗和控制血管生成介导的疾病的材料和方法
US20100098675A1 (en) * 2008-05-30 2010-04-22 Nikolai Tankovich Methods for reducing the side effects of ophthalmic laser surgery
RU2535966C2 (ru) * 2008-09-12 2014-12-20 Криопрашис Криобиоложия Лтда. Клеточная терапия ишемической ткани
CA2743255C (en) 2008-12-03 2014-02-18 Andrew Pecora Infarct area perfusion-improving compositions and methods of vascular injury repair
WO2012005763A1 (en) 2010-07-06 2012-01-12 The Scripps Research Institute Use of myeloid-like progenitor cell populations to treat tumors
US9265813B2 (en) 2011-10-27 2016-02-23 Wellstat Ophthalmics Corporation Vectors encoding rod-derived cone viability factor
CA2870466A1 (en) * 2012-04-16 2013-10-24 The Regents Of The University Of California Ocular therapeutics using embryonic stem cell microvesicles
CA2882802C (en) * 2012-08-24 2021-07-06 Riken Method for producing retinal pigment epithelial cell sheet
WO2020172854A1 (en) * 2019-02-28 2020-09-03 Shenzhen University Use of endothelial progenitor cells (epcs) in rejuvenating microvasculature, preventing aging and treating age-related diseases

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US6908763B1 (en) * 1997-08-22 2005-06-21 The Board Of Trustees Of The Leland Stanford Junior University Mammalian common lymphoid progenitor cell
WO1999055837A2 (en) * 1998-04-28 1999-11-04 Nycomed Imaging As Improvements in or relating to separation processes
US6767737B1 (en) * 1998-08-31 2004-07-27 New York University Stem cells bearing an FGF receptor on the cell surface
US6780627B1 (en) * 2000-01-31 2004-08-24 Millennium Pharmaceuticals, Inc. 22438, 23553, 25278, and 26212 novel human sulfatases
US20030017564A1 (en) * 2001-02-23 2003-01-23 Paul Schimmel Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiogenesis
US20020061587A1 (en) * 2000-07-31 2002-05-23 Piero Anversa Methods and compositions for the repair and/or regeneration of damaged myocardium
WO2003080116A1 (en) * 2002-03-21 2003-10-02 University Of Florida Modulating angiogenesis
WO2004005531A2 (en) * 2002-07-05 2004-01-15 Roger Williams Medical Center Targeting and tracking of cells to specific organs and tissues in vivo

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