JP2010179112A5 - - Google Patents

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Publication number
JP2010179112A5
JP2010179112A5 JP2010050426A JP2010050426A JP2010179112A5 JP 2010179112 A5 JP2010179112 A5 JP 2010179112A5 JP 2010050426 A JP2010050426 A JP 2010050426A JP 2010050426 A JP2010050426 A JP 2010050426A JP 2010179112 A5 JP2010179112 A5 JP 2010179112A5
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Japan
Prior art keywords
active substance
carrier material
composition
pores
resorbable
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JP2010050426A
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English (en)
Japanese (ja)
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JP5090487B2 (ja
JP2010179112A (ja
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Priority claimed from GBGB9808052.6A external-priority patent/GB9808052D0/en
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Publication of JP2010179112A publication Critical patent/JP2010179112A/ja
Publication of JP2010179112A5 publication Critical patent/JP2010179112A5/ja
Application granted granted Critical
Publication of JP5090487B2 publication Critical patent/JP5090487B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2010050426A 1998-04-17 2010-03-08 物質投与用インプラント及びインプラントの製造方法 Expired - Fee Related JP5090487B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9808052.6A GB9808052D0 (en) 1998-04-17 1998-04-17 Implants for administering substances and methods of producing implants
GB9808052.6 1998-04-17

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000544305A Division JP2003513001A (ja) 1998-04-17 1999-04-16 物質投与用インプラント及びインプラントの製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012161631A Division JP5923007B2 (ja) 1998-04-17 2012-07-20 物質投与用インプラント及びインプラントの製造方法

Publications (3)

Publication Number Publication Date
JP2010179112A JP2010179112A (ja) 2010-08-19
JP2010179112A5 true JP2010179112A5 (cg-RX-API-DMAC7.html) 2011-10-13
JP5090487B2 JP5090487B2 (ja) 2012-12-05

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2000544305A Pending JP2003513001A (ja) 1998-04-17 1999-04-16 物質投与用インプラント及びインプラントの製造方法
JP2010050426A Expired - Fee Related JP5090487B2 (ja) 1998-04-17 2010-03-08 物質投与用インプラント及びインプラントの製造方法
JP2012161631A Expired - Lifetime JP5923007B2 (ja) 1998-04-17 2012-07-20 物質投与用インプラント及びインプラントの製造方法
JP2015094005A Ceased JP2015205185A (ja) 1998-04-17 2015-05-01 物質投与用インプラント及びインプラントの製造方法

Family Applications Before (1)

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JP2000544305A Pending JP2003513001A (ja) 1998-04-17 1999-04-16 物質投与用インプラント及びインプラントの製造方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012161631A Expired - Lifetime JP5923007B2 (ja) 1998-04-17 2012-07-20 物質投与用インプラント及びインプラントの製造方法
JP2015094005A Ceased JP2015205185A (ja) 1998-04-17 2015-05-01 物質投与用インプラント及びインプラントの製造方法

Country Status (12)

Country Link
US (9) US7763277B1 (cg-RX-API-DMAC7.html)
EP (3) EP1407764B1 (cg-RX-API-DMAC7.html)
JP (4) JP2003513001A (cg-RX-API-DMAC7.html)
KR (2) KR100655629B1 (cg-RX-API-DMAC7.html)
CN (4) CN103202801B (cg-RX-API-DMAC7.html)
AU (1) AU755703B2 (cg-RX-API-DMAC7.html)
CA (1) CA2328996C (cg-RX-API-DMAC7.html)
DE (1) DE69917625T2 (cg-RX-API-DMAC7.html)
ES (2) ES2222704T3 (cg-RX-API-DMAC7.html)
GB (1) GB9808052D0 (cg-RX-API-DMAC7.html)
NZ (1) NZ507353A (cg-RX-API-DMAC7.html)
WO (1) WO1999053898A1 (cg-RX-API-DMAC7.html)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808052D0 (en) 1998-04-17 1998-06-17 Secr Defence Implants for administering substances and methods of producing implants
GB9924334D0 (en) * 1999-10-15 1999-12-15 Secr Defence Pharmaceutical products and methods of fabrication therefor
GB0008494D0 (en) * 2000-04-07 2000-05-24 Secr Defence Microprojectile delivery system
GB2363115A (en) * 2000-06-10 2001-12-12 Secr Defence Porous or polycrystalline silicon orthopaedic implants
AU2005200352B2 (en) * 2000-06-10 2008-05-15 Psimedica Limited A porous and/or polycrystalline silicon orthopaedic implant
GB2365769A (en) * 2000-08-18 2002-02-27 Secr Defence Skin preparations containing silicon
US7776310B2 (en) 2000-11-16 2010-08-17 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
GB0104383D0 (en) * 2001-02-22 2001-04-11 Psimedica Ltd Cancer Treatment
US7621907B2 (en) * 2002-03-11 2009-11-24 Alcon, Inc. Implantable drug delivery system
GB0324483D0 (en) * 2003-10-21 2003-11-19 Psi Medica Ltd Composite material
EP1677828B1 (en) * 2003-10-21 2012-12-26 PSIMedica Limited Composite material comprising a porous semiconductor impregnated with an organic substance
DE102004021739B4 (de) * 2004-04-30 2007-11-22 Heraeus Kulzer Gmbh Metallimplantat mit Oberflächenbeschichtung
US8709469B2 (en) * 2004-06-30 2014-04-29 Abbott Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
CN101072580B (zh) 2004-10-06 2012-08-22 农业生物技术有限公司 抗体制备方法
WO2006050221A2 (en) 2004-10-29 2006-05-11 The Regents Of The University Of California Porous photonic crystals for drug delivery to the eye
US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
US20090062909A1 (en) 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
EP1909973B1 (en) 2005-07-15 2018-08-22 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
GB0519391D0 (en) * 2005-09-22 2005-11-02 Aion Diagnostics Ltd Imaging agents
PL2019657T3 (pl) 2006-04-26 2015-10-30 Micell Technologies Inc Powłoki zawierające wiele leków
US20080051335A1 (en) * 2006-05-02 2008-02-28 Kleiner Lothar W Methods, compositions and devices for treating lesioned sites using bioabsorbable carriers
WO2008052000A2 (en) 2006-10-23 2008-05-02 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
JP5603598B2 (ja) 2007-01-08 2014-10-08 ミセル テクノロジーズ、インコーポレイテッド 生物分解層を有するステント
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
US9433516B2 (en) 2007-04-17 2016-09-06 Micell Technologies, Inc. Stents having controlled elution
EP2170418B1 (en) 2007-05-25 2016-03-16 Micell Technologies, Inc. Polymer films for medical device coating
CA2696139C (en) 2007-07-10 2018-04-17 The Regents Of The University Of California Materials and methods for delivering compositions to selected tissues
MX2010011485A (es) 2008-04-17 2011-03-01 Micell Technologies Inc Stents que contienen capas bioadsorbibles.
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
WO2010009335A1 (en) 2008-07-17 2010-01-21 Micell Technologies, Inc. Drug delivery medical device
US8834913B2 (en) 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
US20110300222A1 (en) * 2009-02-20 2011-12-08 The Regents Of The University Of California Luminescent porous silicon nanoparticles, methods of making and using same
EP2413847A4 (en) 2009-04-01 2013-11-27 Micell Technologies Inc COATED STENTS
CN102405042A (zh) 2009-05-04 2012-04-04 普西维达公司 多孔硅药物洗脱颗粒
PL2371398T3 (pl) 2009-08-25 2013-08-30 Prostec Co Ltd Wyroby medyczne i sposób ich wytwarzania
EP2531140B1 (en) 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
CN103081107B (zh) 2010-03-09 2017-02-08 得克萨斯州大学系统董事会 多孔和非多孔纳米结构
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
EP2560576B1 (en) 2010-04-22 2018-07-18 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
WO2012005783A1 (en) 2010-07-09 2012-01-12 Board Of Regents Of The University Of Texas System Biodegradable scaffolds
WO2012009684A2 (en) 2010-07-16 2012-01-19 Micell Technologies, Inc. Drug delivery medical device
CA2810842C (en) 2010-09-09 2018-06-26 Micell Technologies, Inc. Macrolide dosage forms
EP2635255B1 (en) 2010-11-01 2019-08-21 EyePoint Pharmaceuticals US, Inc. Bioerodible silicon-based devices for delivery of therapeutic agents
US8679093B2 (en) 2010-11-23 2014-03-25 Microchips, Inc. Multi-dose drug delivery device and method
US10464100B2 (en) 2011-05-31 2019-11-05 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
WO2013012689A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
US20140205971A1 (en) * 2013-01-18 2014-07-24 The Trustees Of The Stevens Institute Of Technology Modification of root form dental implants for accelerated tissue regeneration
CA2905419C (en) 2013-03-12 2020-04-28 Micell Technologies, Inc. Bioabsorbable biomedical implants
CA2904077A1 (en) 2013-03-15 2014-09-25 Psivida Us, Inc. Bioerodible silicon-based compositions for delivery of therapeutic agents
CA2912387C (en) 2013-05-15 2019-04-16 Micell Technologies, Inc. Bioabsorbable biomedical implants
AU2016291224B2 (en) 2015-07-09 2021-12-23 The Regents Of The University Of California Fusogenic liposome-coated porous silicon nanoparticles
AU2017250300B2 (en) 2016-04-14 2023-04-06 Massachusetts Institute Of Technology Porous silicon materials comprising a metal silicate for delivery of therapeutic agents
MX2020012459A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
WO2019226516A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
EP3810092A4 (en) * 2018-06-25 2022-04-20 Titan Pharmaceuticals, Inc. LOADED POROUS STRUCTURES FOR USE AS IMPLANTS
EP4329734A4 (en) 2021-04-26 2025-04-02 Celanese EVA Performance Polymers LLC Implantable device for the delayed release of a macromolecular drug compound

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832458A (en) * 1971-12-06 1974-08-27 River C Foundation Hydrophilic silicone composition and method
US4036979A (en) * 1974-01-25 1977-07-19 American Cyanamid Company Compositions containing 4,5,6,7-tetrahydrobenz[b]thien-4-yl-ureas or derivatives and methods of enhancing growth rate
US3919723A (en) * 1974-05-20 1975-11-18 Friedrichsfeld Gmbh Bone shaft or bone joint prosthesis and process
US3919060A (en) * 1974-06-14 1975-11-11 Ibm Method of fabricating semiconductor device embodying dielectric isolation
JPS59101145A (ja) 1982-11-30 1984-06-11 日本特殊陶業株式会社 薬液含浸多孔質セラミツクス
JPS59131346A (ja) * 1983-01-17 1984-07-28 日本特殊陶業株式会社 薬液含浸多孔質セラミツクスの製造法
DE3423667A1 (de) 1984-05-08 1985-11-28 Rüdiger Dipl.-Ing. 5204 Lohmar Scheunemann Implantat fuer knochen- und zahnwurzelersatz mit spezieller uebergangsstruktur zwischen knochen und implantatkern und knochenseitig ganz oder teilweise resorbierbarer matrix
GB8422876D0 (en) 1984-09-11 1984-10-17 Secr Defence Silicon implant devices
US4608048A (en) * 1984-12-06 1986-08-26 Alza Corporation Dispensing device with drug delivery patterns
US5057082A (en) 1988-11-04 1991-10-15 Plastic Injectors, Inc. Trocar assembly
DE69001898T2 (de) 1989-03-17 1993-09-23 Pitman Moore Inc Kontrollierte, verzoegerte wirkstofffreisetzung von makromolekularen proteinen.
GB8927709D0 (en) 1989-12-07 1990-02-07 Secretary Of The State For Def Silicon quantum wires
US5167625A (en) 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5366454A (en) 1993-03-17 1994-11-22 La Corporation De L'ecole Polytechnique Implantable medication dispensing device
US5370630A (en) 1993-11-12 1994-12-06 Smidebush; Michael J. Device for injection of fluidic materials into body tissue
US5591453A (en) * 1994-07-27 1997-01-07 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US5817327A (en) 1994-07-27 1998-10-06 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US5665114A (en) 1994-08-12 1997-09-09 Meadox Medicals, Inc. Tubular expanded polytetrafluoroethylene implantable prostheses
US5792099A (en) 1995-02-14 1998-08-11 Decamp; Dennis Syringe and cannula for insertion of viscoelastic material into an eye and method of using same
JP3768536B2 (ja) 1995-04-03 2006-04-19 アボツト・ラボラトリーズ 低温溶融性薬物と制御放出のための添加物との均質混合物
US6096344A (en) 1995-07-28 2000-08-01 Advanced Polymer Systems, Inc. Bioerodible porous compositions
GB9611437D0 (en) * 1995-08-03 1996-08-07 Secr Defence Biomaterial
US5665428A (en) 1995-10-25 1997-09-09 Macromed, Inc. Preparation of peptide containing biodegradable microspheres by melt process
DE19608423A1 (de) * 1996-03-05 1997-09-11 Merck Patent Gmbh Implantate mit phasenweiser Arzneistoffabgabe
US7070590B1 (en) 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US5922299A (en) * 1996-11-26 1999-07-13 Battelle Memorial Institute Mesoporous-silica films, fibers, and powders by evaporation
JP3217286B2 (ja) 1996-12-19 2001-10-09 科学技術振興事業団 Dna固定化複合体
US6696258B1 (en) * 1998-01-20 2004-02-24 Drexel University Mesoporous materials and methods of making the same
US6060036A (en) 1998-02-09 2000-05-09 Implant Sciences Corporation Radioactive seed implants
GB9808052D0 (en) * 1998-04-17 1998-06-17 Secr Defence Implants for administering substances and methods of producing implants
GB9815819D0 (en) 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
HK1040921B (en) 1998-12-23 2005-12-30 Alza Corporation Dosage forms comprising porous particles
AU7881000A (en) 1999-08-16 2001-03-13 Henceforth Hibernia, Inc. Therapeutic and prophylactic compositions including catalytic biomimetic solids and methods to prepare and use them
GB9924334D0 (en) 1999-10-15 1999-12-15 Secr Defence Pharmaceutical products and methods of fabrication therefor
WO2001028587A2 (en) 1999-10-18 2001-04-26 Ferx Incorporated Magnetic targeted carrier
SE9903958D0 (sv) 1999-11-02 1999-11-02 Boerje Sellergren Porous materials for selective binding or transport of molecular guests
US6521284B1 (en) 1999-11-03 2003-02-18 Scimed Life Systems, Inc. Process for impregnating a porous material with a cross-linkable composition
AUPQ573300A0 (en) 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
EA005619B1 (ru) 2000-02-28 2005-04-28 Авентис Фарма С.А. Композиция, включающая камптотецин и производное пиримидина, для лечения рака
GB0008494D0 (en) * 2000-04-07 2000-05-24 Secr Defence Microprojectile delivery system
GB2365769A (en) 2000-08-18 2002-02-27 Secr Defence Skin preparations containing silicon
GB0104383D0 (en) 2001-02-22 2001-04-11 Psimedica Ltd Cancer Treatment
WO2002096389A1 (en) 2001-05-30 2002-12-05 Microchips, Inc. Conformal coated microchip reservoir devices
US7090681B2 (en) 2002-09-18 2006-08-15 Allergan, Inc. Methods and apparatus for delivery of ocular implants
WO2004071949A2 (en) 2003-02-13 2004-08-26 The Regents Of The University Of California Nanostructured casting of organic and bio-polymers in porous silicon templates
US7433811B2 (en) 2003-05-06 2008-10-07 The Regents Of The University Of California Direct patterning of silicon by photoelectrochemical etching
US7563451B2 (en) 2003-07-22 2009-07-21 Iowa State University Research Foundation, Inc. Capped mesoporous silicates
EP1677828B1 (en) 2003-10-21 2012-12-26 PSIMedica Limited Composite material comprising a porous semiconductor impregnated with an organic substance
GB0324483D0 (en) 2003-10-21 2003-11-19 Psi Medica Ltd Composite material
US20050181049A1 (en) 2003-11-19 2005-08-18 Dong Liang C. Composition and method for enhancing bioavailability
MX2007003280A (es) 2004-09-17 2007-05-24 Ormco Corp Aparato de tratamiento medico y metodo de manufactura de aguja.
US20060067979A1 (en) 2004-09-30 2006-03-30 Bausch & Lomb Incorporated Ophthalmic drug release device for multiple drug release
US20080241242A1 (en) 2004-10-05 2008-10-02 Francesco Caruso Porous Polyelectrolyte Materials
WO2006050221A2 (en) 2004-10-29 2006-05-11 The Regents Of The University Of California Porous photonic crystals for drug delivery to the eye
WO2006067979A1 (ja) 2004-12-21 2006-06-29 Nec Corporation フィルム外装電気デバイス用ケース
JP2007091716A (ja) 2005-08-29 2007-04-12 Kuraray Co Ltd 水中薬剤徐放性微粒子及びその製造方法
GB0526332D0 (en) 2005-12-23 2006-02-01 Psimedica Ltd Pharmaceutical product
EP1999247A4 (en) 2006-03-14 2011-08-31 Univ Rochester CELL CULTURAL DEVICES WITH ULTRADOOR POROUS MEMBRANE AND APPLICATIONS THEREOF
ES2640458T3 (es) 2006-03-31 2017-11-03 Mati Therapeutics Inc. Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa
US20080057102A1 (en) 2006-08-21 2008-03-06 Wouter Roorda Methods of manufacturing medical devices for controlled drug release
CA2696139C (en) 2007-07-10 2018-04-17 The Regents Of The University Of California Materials and methods for delivering compositions to selected tissues
GB0817936D0 (en) 2008-09-30 2008-11-05 Intrinsiq Materials Global Ltd Porous materials
GB0817938D0 (en) 2008-09-30 2008-11-05 Intrinsiq Materials Global Ltd Cosmetic formulations
US20120045515A1 (en) 2009-02-04 2012-02-23 Ye Liu Hollow silica particle with a polymer thereon
US20110300222A1 (en) 2009-02-20 2011-12-08 The Regents Of The University Of California Luminescent porous silicon nanoparticles, methods of making and using same
JP5382700B2 (ja) 2009-03-27 2014-01-08 独立行政法人産業技術総合研究所 ロッド状多孔質シリカ粒子
CN102405042A (zh) 2009-05-04 2012-04-04 普西维达公司 多孔硅药物洗脱颗粒
EP2635255B1 (en) 2010-11-01 2019-08-21 EyePoint Pharmaceuticals US, Inc. Bioerodible silicon-based devices for delivery of therapeutic agents
WO2012088304A2 (en) 2010-12-22 2012-06-28 Psivida Us, Inc. Two-piece injectable drug delivery device with heat-cured seal

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