JP2010006705A5 - - Google Patents
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- Publication number
- JP2010006705A5 JP2010006705A5 JP2008155676A JP2008155676A JP2010006705A5 JP 2010006705 A5 JP2010006705 A5 JP 2010006705A5 JP 2008155676 A JP2008155676 A JP 2008155676A JP 2008155676 A JP2008155676 A JP 2008155676A JP 2010006705 A5 JP2010006705 A5 JP 2010006705A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- seq
- affinity ligand
- her2
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims description 13
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims description 13
- 125000000539 amino acid group Chemical group 0.000 claims description 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 5
- 239000003446 ligand Substances 0.000 claims 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 230000002018 overexpression Effects 0.000 claims 6
- 230000001225 therapeutic effect Effects 0.000 claims 6
- 229920001184 polypeptide Polymers 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 206010014733 Endometrial cancer Diseases 0.000 claims 2
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 2
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 2
- 206010038389 Renal cancer Diseases 0.000 claims 2
- 201000010982 kidney cancer Diseases 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 101100314454 Caenorhabditis elegans tra-1 gene Proteins 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 206010061934 Salivary gland cancer Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 206010047741 Vulval cancer Diseases 0.000 claims 1
- 208000004354 Vulvar Neoplasms Diseases 0.000 claims 1
- 208000008383 Wilms tumor Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000003914 endometrial carcinoma Diseases 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 201000000050 myeloid neoplasm Diseases 0.000 claims 1
- 201000008026 nephroblastoma Diseases 0.000 claims 1
- 201000003804 salivary gland carcinoma Diseases 0.000 claims 1
- 230000009834 selective interaction Effects 0.000 claims 1
- 206010041823 squamous cell carcinoma Diseases 0.000 claims 1
- 208000017572 squamous cell neoplasm Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 201000002510 thyroid cancer Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 201000005102 vulva cancer Diseases 0.000 claims 1
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008155676A JP2010006705A (ja) | 2008-06-13 | 2008-06-13 | Ｈｅｒ２サブセット |
| US12/997,823 US20110158988A1 (en) | 2008-06-13 | 2008-12-12 | Antibodies against extracellular domains 2 and 3 or her2 |
| PCT/SE2008/000694 WO2009151356A1 (en) | 2008-06-13 | 2008-12-12 | Antibodies against extracellular domains 2 and 3 or her2 |
| KR1020127017264A KR20130026418A (ko) | 2008-06-13 | 2008-12-12 | Ｈｅｒ2 의 세포외 도메인 2 및 3 에 대한 항체 |
| AU2008357729A AU2008357729A1 (en) | 2008-06-13 | 2008-12-12 | Antibodies against extracellular domain 2 and 3 of HER2 |
| CA2727941A CA2727941A1 (en) | 2008-06-13 | 2008-12-12 | Antibodies against extracellular domains 2 and 3 or her2 |
| EP08874636A EP2294088A1 (en) | 2008-06-13 | 2008-12-12 | Antibodies against extracellular domains 2 and 3 or her2 |
| CN2008801297639A CN102099376A (zh) | 2008-06-13 | 2008-12-12 | 针对her2的细胞外结构域2和3的抗体 |
| KR1020107027939A KR20110036534A (ko) | 2008-06-13 | 2008-12-12 | Ｈｅｒ2 의 세포외 도메인 2 및 3 에 대한 항체 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008155676A JP2010006705A (ja) | 2008-06-13 | 2008-06-13 | Ｈｅｒ２サブセット |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010006705A JP2010006705A (ja) | 2010-01-14 |
| JP2010006705A5 true JP2010006705A5 (enExample) | 2011-07-21 |
Family
ID=40427661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008155676A Pending JP2010006705A (ja) | 2008-06-13 | 2008-06-13 | Ｈｅｒ２サブセット |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110158988A1 (enExample) |
| EP (1) | EP2294088A1 (enExample) |
| JP (1) | JP2010006705A (enExample) |
| KR (2) | KR20130026418A (enExample) |
| CN (1) | CN102099376A (enExample) |
| AU (1) | AU2008357729A1 (enExample) |
| CA (1) | CA2727941A1 (enExample) |
| WO (1) | WO2009151356A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101759209B1 (ko) | 2010-01-22 | 2017-07-19 | 성균관대학교산학협력단 | Ｈｅｒ－２ 과발현 유방암 세포 또는 조직에 특이적으로 결합할 수 있는 핵산 압타머 및 그 용도 |
| US8609095B2 (en) | 2010-03-04 | 2013-12-17 | Symphogen A/S | Anti-HER2 antibodies and compositions |
| AU2016201799B2 (en) * | 2010-05-27 | 2017-09-07 | Genmab A/S | Monoclonal antibodies aganst HER2 epitope |
| CA3051311A1 (en) * | 2010-05-27 | 2011-12-01 | Genmab A/S | Monoclonal antibodies against her2 |
| EP2575880B1 (en) * | 2010-05-27 | 2019-01-16 | Genmab A/S | Monoclonal antibodies against her2 epitope |
| JP2014514314A (ja) | 2011-04-20 | 2014-06-19 | ゲンマブ エー／エス | Ｈｅｒ２およびｃｄ３に対する二重特異性抗体 |
| CN105017425B (zh) * | 2014-04-30 | 2018-02-16 | 京天成生物技术(北京)有限公司 | 抗her2中和活性单克隆抗体及其应用 |
| JP6971319B2 (ja) | 2016-12-28 | 2021-11-24 | グリーン・クロス・ラブ・セル・コーポレイション | キメラ抗原受容体及びそれを発現するナチュラルキラー細胞 |
| EP3712178A4 (en) | 2017-11-14 | 2021-08-11 | Green Cross Lab Cell Corporation | ANTI-HER2 ANTIBODIES OR ANTIGIBODY FRAGMENT THEREOF AND CHIMERAIR ANTIGEN RECEPTOR WITH IT |
| US11649294B2 (en) | 2017-11-14 | 2023-05-16 | GC Cell Corporation | Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same |
| AU2018383096A1 (en) * | 2017-12-11 | 2020-06-11 | Medizinische Universitaet Wien | A method of producing a vaccine composition and uses thereof |
| WO2020036869A1 (en) | 2018-08-16 | 2020-02-20 | Emd Millipore Corporation | Closed bioprocessing device |
| US20210238305A1 (en) * | 2019-03-01 | 2021-08-05 | Remegen Co., Ltd. | Antibody for her2 concomitant diagnosis immunohistochemical detection and application thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5801005A (en) * | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
| US6514942B1 (en) * | 1995-03-14 | 2003-02-04 | The Board Of Regents, The University Of Texas System | Methods and compositions for stimulating T-lymphocytes |
| US5783404A (en) * | 1995-04-13 | 1998-07-21 | Amgen Inc. | Methods and compositions for determining HER-2/neu expression using monoclonal antibodies |
| EP1239866A4 (en) * | 1999-12-10 | 2005-02-09 | Epimmune Inc | INDUCTION OF HER2 / NEU CELLULAR IMMUNE RESPONSES USING PEPTIDE AND NUCLEIC ACID-CONTAINING COMPOSITIONS |
| IL159177A0 (en) * | 2001-06-20 | 2004-06-01 | Prochon Biotech Ltd | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
| CN1136917C (zh) * | 2001-10-10 | 2004-02-04 | 北京迪威华宇生物技术有限公司 | 一种卡介苗热休克蛋白65和多表位her-2抗原融合蛋白重组蛋白疫苗 |
| AU2003296330A1 (en) * | 2002-12-10 | 2004-06-30 | Epimmune Inc. | Hla-a1, a2 -a3,-a24,-b7,and -b44 tumor associated antigen peptides and compositions |
| US7767792B2 (en) * | 2004-02-20 | 2010-08-03 | Ludwig Institute For Cancer Research Ltd. | Antibodies to EGF receptor epitope peptides |
| SV2006002143A (es) * | 2004-06-16 | 2006-01-26 | Genentech Inc | Uso de un anticuerpo para el tratamiento del cancer resistente al platino |
| AU2005287404B2 (en) * | 2004-07-22 | 2009-05-07 | Genentech, Inc. | HER2 antibody composition |
| ES2348312T3 (es) * | 2006-04-13 | 2010-12-02 | Bio Life Science Forschungs- Und Entwicklungsges.M.B.H. | Vacuna her-2/neu a base de múltiples péptidos. |
| CA2655205A1 (en) * | 2006-06-12 | 2007-12-21 | Receptor Biologix Inc. | Pan-cell surface receptor- specific therapeutics |
| CN101165068B (zh) * | 2006-10-18 | 2011-09-21 | 上海复旦张江生物医药股份有限公司 | 抗HER2/ErbB2抗原的单克隆抗体及其制备方法和药物组合物 |
-
2008
- 2008-06-13 JP JP2008155676A patent/JP2010006705A/ja active Pending
- 2008-12-12 CA CA2727941A patent/CA2727941A1/en not_active Abandoned
- 2008-12-12 US US12/997,823 patent/US20110158988A1/en not_active Abandoned
- 2008-12-12 EP EP08874636A patent/EP2294088A1/en not_active Withdrawn
- 2008-12-12 WO PCT/SE2008/000694 patent/WO2009151356A1/en not_active Ceased
- 2008-12-12 AU AU2008357729A patent/AU2008357729A1/en not_active Abandoned
- 2008-12-12 KR KR1020127017264A patent/KR20130026418A/ko not_active Withdrawn
- 2008-12-12 CN CN2008801297639A patent/CN102099376A/zh active Pending
- 2008-12-12 KR KR1020107027939A patent/KR20110036534A/ko not_active Ceased