JP2010111679A5 - - Google Patents
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- JP2010111679A5 JP2010111679A5 JP2009288124A JP2009288124A JP2010111679A5 JP 2010111679 A5 JP2010111679 A5 JP 2010111679A5 JP 2009288124 A JP2009288124 A JP 2009288124A JP 2009288124 A JP2009288124 A JP 2009288124A JP 2010111679 A5 JP2010111679 A5 JP 2010111679A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- monoclonal antibody
- composition
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35882402P | 2002-02-21 | 2002-02-21 | |
| US60/358,824 | 2002-02-21 | ||
| US38306802P | 2002-05-23 | 2002-05-23 | |
| US60/383,068 | 2002-05-23 | ||
| US43149902P | 2002-12-05 | 2002-12-05 | |
| US60/431,499 | 2002-12-05 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004508271A Division JP4488351B2 (ja) | 2002-02-21 | 2003-02-21 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012248466A Division JP5271443B2 (ja) | 2002-02-21 | 2012-11-12 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010111679A JP2010111679A (ja) | 2010-05-20 |
| JP2010111679A5 true JP2010111679A5 (enExample) | 2011-05-06 |
| JP5199228B2 JP5199228B2 (ja) | 2013-05-15 |
Family
ID=33425052
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004508271A Expired - Fee Related JP4488351B2 (ja) | 2002-02-21 | 2003-02-21 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
| JP2008325146A Expired - Fee Related JP4514820B2 (ja) | 2002-02-21 | 2008-12-22 | 可溶型の炭酸脱水酵素IX(s−CA IX)、s−CA IXを検出するためのアッセイ、CA IXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCA IX特異的モノクローナル抗体 |
| JP2009288124A Expired - Fee Related JP5199228B2 (ja) | 2002-02-21 | 2009-12-18 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
| JP2012248466A Expired - Fee Related JP5271443B2 (ja) | 2002-02-21 | 2012-11-12 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004508271A Expired - Fee Related JP4488351B2 (ja) | 2002-02-21 | 2003-02-21 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
| JP2008325146A Expired - Fee Related JP4514820B2 (ja) | 2002-02-21 | 2008-12-22 | 可溶型の炭酸脱水酵素IX(s−CA IX)、s−CA IXを検出するためのアッセイ、CA IXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCA IX特異的モノクローナル抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012248466A Expired - Fee Related JP5271443B2 (ja) | 2002-02-21 | 2012-11-12 | 可溶型の炭酸脱水酵素IX(s−CAIX)、s−CAIXを検出するためのアッセイ、CAIXとHER−2/neu/c−erbB−2の同時発現、非免疫優性エピトープに対するCAIX特異的モノクローナル抗体 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US7846673B2 (enExample) |
| EP (1) | EP1487972B1 (enExample) |
| JP (4) | JP4488351B2 (enExample) |
| AU (1) | AU2003217606C1 (enExample) |
| CA (1) | CA2477163C (enExample) |
| DK (2) | DK1487972T3 (enExample) |
| HU (3) | HUE026218T2 (enExample) |
| WO (1) | WO2004005348A1 (enExample) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2508596T1 (sl) * | 2002-02-21 | 2016-01-29 | Institute Of Virology Slovak Academy Of Sciences | Monoklonska protitelesa, specifična za MN/CA IX, proizvedena iz MN/CA IX deficientnih miši, in postopki uporabe |
| DK1487972T3 (en) * | 2002-02-21 | 2015-10-19 | Inst Virology | MN / CA IX-specific monoclonal antibodies generated from MN / CA IX-poor mice, as well as methods of use. |
| US20090162382A1 (en) * | 2002-03-01 | 2009-06-25 | Bernett Matthew J | Optimized ca9 antibodies and methods of using the same |
| US8936914B2 (en) * | 2002-04-16 | 2015-01-20 | The Regents Of The University Of California | Methods of renal cell carcinoma prognosis and treatment selection with carbonic anhydrase IX |
| US20090239247A1 (en) * | 2002-12-13 | 2009-09-24 | Harris Adrian L | MN and Hypoxia |
| US8003625B2 (en) | 2005-06-29 | 2011-08-23 | Threshold Pharmaceuticals, Inc. | Phosphoramidate alkylator prodrugs |
| EP2074225B1 (en) * | 2006-10-10 | 2014-12-03 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Prostate cancer-specific alterations in erg gene expression and detection and treatment methods based on those alterations |
| US7820159B2 (en) * | 2006-10-31 | 2010-10-26 | Instiute of Virology of the Slovak Academy of Sciences | MN/CA IX and EGFR pathway inhibition |
| EP2219668A1 (en) * | 2007-11-02 | 2010-08-25 | Wilex AG | Binding epitopes for g250 antibody |
| JP5313164B2 (ja) | 2007-11-19 | 2013-10-09 | 旭化成ケミカルズ株式会社 | イソシアネートおよび芳香族ヒドロキシ化合物の製造方法 |
| EP2403964B1 (en) | 2009-03-02 | 2021-09-08 | Massachusetts Institute of Technology | Methods and products for in vivo enzyme profiling |
| EP2674756B1 (en) * | 2009-09-10 | 2016-08-03 | Bruker Daltonik GmbH | Determining the expression status of human epidermal growth factor receptor 2 (HER2) in biological samples |
| ES2881535T3 (es) | 2011-03-15 | 2021-11-29 | Massachusetts Inst Technology | Detección multiplexada con indicadores codificados con isótopos |
| US9080849B2 (en) | 2011-07-29 | 2015-07-14 | Milwaukee Electric Tool Corporation | Tape measure |
| CA2784047C (en) | 2011-07-29 | 2015-08-11 | Milwaukee Electric Tool Corporation | Tape measure |
| US8863399B2 (en) | 2011-08-26 | 2014-10-21 | Milwaukee Electric Tool Corporation | Tape measure |
| EP2508890A1 (en) * | 2011-10-25 | 2012-10-10 | Roche Diagnostics GmbH | CAIX based diagnosis of heart failure |
| US9254299B2 (en) | 2011-12-22 | 2016-02-09 | Threshold Pharmaceuticals, Inc. | Administration of hypoxia activated prodrugs in combination with Chk1 inhibitors for treating cancer |
| US9267778B2 (en) | 2012-01-19 | 2016-02-23 | Milwaukee Electric Tool Corporation | Tape measure |
| WO2013116385A1 (en) * | 2012-01-31 | 2013-08-08 | Threshold Pharmaceuticals, Inc. | Predictive biomarker for hypoxia-activated prodrug therapy |
| JP2015155795A (ja) * | 2012-05-21 | 2015-08-27 | 東レ株式会社 | 癌の検出方法 |
| USD733597S1 (en) | 2012-07-30 | 2015-07-07 | Milwaukee Electric Tool Corporation | Tape measure |
| ES2738310T3 (es) | 2012-10-12 | 2020-01-21 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de las mismas |
| CA2905181C (en) | 2013-03-13 | 2020-06-02 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof for providing targeted therapy |
| WO2014197840A1 (en) * | 2013-06-07 | 2014-12-11 | Massachusetts Institute Of Technology | Affinity-based detection of ligand-encoded synthetic biomarkers |
| US10071109B2 (en) | 2013-11-06 | 2018-09-11 | Molecular Templates, Inc. | Predictive biomarker for hypoxia-activated prodrug therapy |
| US10188746B2 (en) | 2014-09-10 | 2019-01-29 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| KR102754019B1 (ko) | 2014-10-29 | 2025-01-14 | 바이시클러드 리미티드 | Mt1-mmp에 특이적인 바이사이클릭 펩타이드 리간드 |
| EP3286337A4 (en) * | 2015-04-23 | 2018-12-12 | Cedars-Sinai Medical Center | Automated delineation of nuclei for three dimensional (3-d) high content screening |
| USD785475S1 (en) | 2015-12-10 | 2017-05-02 | Milwaukee Electric Tool Corporation | Tape measure |
| USD785476S1 (en) | 2015-12-10 | 2017-05-02 | Milwaukee Electric Tool Corporation | Tape measure |
| USD783430S1 (en) | 2016-01-07 | 2017-04-11 | Milwaukee Electric Tool Corporation | Tape measure |
| USD783429S1 (en) | 2016-01-07 | 2017-04-11 | Milwaukee Electric Tool Corporation | Tape measure |
| USD787347S1 (en) | 2016-01-07 | 2017-05-23 | Milwaukee Electric Tool Corporation | Tape measure |
| EP3440013A4 (en) | 2016-04-08 | 2021-03-17 | Massachusetts Institute of Technology | METHOD FOR SPECIFIC PROFILING OF PROTEASE ACTIVITY ON LYMPH NODES |
| CA3022928A1 (en) | 2016-05-05 | 2017-11-09 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
| USD788611S1 (en) | 2016-06-01 | 2017-06-06 | Milwaukee Electric Tool Corporation | Tape measure |
| WO2018069289A1 (en) | 2016-10-11 | 2018-04-19 | Medimmune Limited | Antibody-drug conjugates with immune-mediated therapy agents |
| US11730819B2 (en) | 2016-12-23 | 2023-08-22 | Bicycletx Limited | Peptide derivatives having novel linkage structures |
| AU2018248327B2 (en) | 2017-04-07 | 2024-10-10 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
| US10857196B2 (en) | 2017-04-27 | 2020-12-08 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| CN111032678A (zh) | 2017-06-26 | 2020-04-17 | 拜西克尔德有限公司 | 具有可检测部分的双环肽配体和其用途 |
| ES2926195T3 (es) | 2017-08-04 | 2022-10-24 | Bicycletx Ltd | Ligandos peptídicos bicíclicos específicos de CD137 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| AU2019224659A1 (en) | 2018-02-23 | 2020-10-15 | Bicycletx Limited | Multimeric bicyclic peptide ligands |
| US11054428B2 (en) | 2018-03-05 | 2021-07-06 | Massachusetts Institute Of Technology | Inhalable nanosensors with volatile reporters and uses thereof |
| SG11202010469QA (en) | 2018-05-23 | 2020-11-27 | Adc Therapeutics Sa | Molecular adjuvant |
| US11028425B2 (en) | 2018-06-08 | 2021-06-08 | Glympse Bio, Inc. | Diagnosis and monitoring of liver disease |
| US11732009B2 (en) | 2018-06-08 | 2023-08-22 | Glympse Bio, Inc. | Activity sensor with tunable analyte |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| WO2020068920A2 (en) | 2018-09-25 | 2020-04-02 | Massachusetts Institute Of Technology | Lung protease nanosensors and uses thereof |
| US10919937B2 (en) | 2018-10-23 | 2021-02-16 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| CN113474045A (zh) | 2018-12-21 | 2021-10-01 | 拜斯科技术开发有限公司 | Pd-l1特异性的双环肽配体 |
| US12551567B2 (en) | 2018-12-21 | 2026-02-17 | Bicyclerd Limited | Bicyclic peptide ligands specific for PD-L1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| WO2020150560A1 (en) | 2019-01-17 | 2020-07-23 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
| US12338483B2 (en) | 2019-02-28 | 2025-06-24 | Georgia Tech Research Corporation | Compositions and methods for logic-gated profiling of biologic activity |
| CA3139278A1 (en) * | 2019-05-06 | 2020-11-12 | Navi Bio-Therapeutics, Inc. | Anti-carbonic anhydrase ix antibody |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| CA3156540A1 (en) * | 2019-11-05 | 2021-05-14 | Miriam Zatovicova | Humanized anti-ca ix antibodies and methods of their use |
| CN111273036B (zh) * | 2020-03-06 | 2021-06-15 | 中国农业科学院兰州兽医研究所 | 检测口蹄疫非结构蛋白抗体的单抗竞争化学发光试剂盒 |
| CA3189761A1 (en) | 2020-08-03 | 2022-02-10 | Gemma Mudd | Peptide-based linkers |
| CN116438456A (zh) | 2020-09-11 | 2023-07-14 | 格里姆普斯生物股份有限公司 | 用于疾病检测/诊断、分期、监测和治疗的离体蛋白酶活性检测 |
| US20230372528A1 (en) | 2020-10-16 | 2023-11-23 | University Of Georgia Research Foundation, Inc. | Glycoconjugates |
| GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
| CN117980327A (zh) | 2021-11-03 | 2024-05-03 | 杭州多禧生物科技有限公司 | 抗体的特异性偶联 |
| CN116167592B (zh) * | 2023-04-20 | 2023-06-23 | 交通运输部天津水运工程科学研究所 | 一种河流溢油风险防控和决策支持系统 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5401638A (en) | 1986-06-04 | 1995-03-28 | Oncogene Science, Inc. | Detection and quantification of neu related proteins in the biological fluids of humans |
| US4968603A (en) | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
| US5989838A (en) | 1992-03-11 | 1999-11-23 | Institute Of Virology, Slovak Academy Of Sciences | Immunological methods of detecting MN proteins and MN polypeptides |
| US6297041B1 (en) * | 1992-03-11 | 2001-10-02 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US5387676A (en) | 1992-03-11 | 1995-02-07 | Ciba Corning Diagnostics Corp. | MN gene and protein |
| US6297051B1 (en) | 1997-01-24 | 2001-10-02 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US5981711A (en) | 1992-03-11 | 1999-11-09 | Institute Of Virology, Slovak Academy Of Sciences | MN-specific antibodies and hybridomas |
| WO2000024913A2 (en) | 1998-10-23 | 2000-05-04 | Bayer Corporation | Mn gene and protein |
| US6774117B1 (en) | 1992-03-11 | 2004-08-10 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US6204370B1 (en) | 1992-03-11 | 2001-03-20 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US6069242A (en) | 1992-03-11 | 2000-05-30 | Institute Of Virology, Slovak Academy Of Sciences | MN gene and protein |
| US5955075A (en) | 1992-03-11 | 1999-09-21 | Institute Of Virology, Slovak Academy Of Sciences | Method of inhibiting tumor growth using antibodies to MN protein |
| US6093548A (en) | 1992-03-11 | 2000-07-25 | Institute Of Virology, Slovak Academy Of Sciences | Detection and quantitation of MN-specific antibodies. |
| US6027887A (en) | 1992-03-11 | 2000-02-22 | Institute Of Virology, Solvak Academy Of Sciences | MN gene and protein |
| US5972353A (en) | 1992-03-11 | 1999-10-26 | Institute Of Virology, Slovak Academy Of Sciences | MN proteins, polypeptides, fusion proteins and fusion polypeptides |
| AU2861695A (en) * | 1994-06-15 | 1996-01-05 | Ciba Corning Diagnostics Corp. | Mn gene and protein |
| US6451977B1 (en) * | 1998-02-26 | 2002-09-17 | Genentech, Inc. | Fused polypeptides |
| EP1461082A4 (en) * | 2001-12-03 | 2006-06-28 | Abgenix Inc | ANTIBODIES AGAINST THE TUMOR ANTIGEN OF CARBON IX ANHYDRASE (CA IX) |
| DK1487972T3 (en) * | 2002-02-21 | 2015-10-19 | Inst Virology | MN / CA IX-specific monoclonal antibodies generated from MN / CA IX-poor mice, as well as methods of use. |
| WO2004017923A2 (en) | 2002-08-23 | 2004-03-04 | Chiron Corporation | Compositions and methods of therapy for cancers characterized by expression of the tumor-associated antigen mn/ca ix |
| WO2008103327A2 (en) | 2007-02-20 | 2008-08-28 | Bayer Pharmaceuticals Corporation | Mn/ca ix and bladder cancer |
| EP2219668A1 (en) * | 2007-11-02 | 2010-08-25 | Wilex AG | Binding epitopes for g250 antibody |
-
2003
- 2003-02-21 DK DK03713562.1T patent/DK1487972T3/en active
- 2003-02-21 JP JP2004508271A patent/JP4488351B2/ja not_active Expired - Fee Related
- 2003-02-21 DK DK15180634.6T patent/DK3031910T3/en active
- 2003-02-21 EP EP03713562.1A patent/EP1487972B1/en not_active Expired - Lifetime
- 2003-02-21 HU HUE12157145A patent/HUE026218T2/en unknown
- 2003-02-21 CA CA2477163A patent/CA2477163C/en not_active Expired - Fee Related
- 2003-02-21 HU HUE03713562A patent/HUE026277T2/en unknown
- 2003-02-21 AU AU2003217606A patent/AU2003217606C1/en not_active Ceased
- 2003-02-21 HU HUE15180634A patent/HUE036891T2/hu unknown
- 2003-02-22 WO PCT/US2003/005137 patent/WO2004005348A1/en not_active Ceased
-
2004
- 2004-08-19 US US10/921,590 patent/US7846673B2/en not_active Expired - Fee Related
-
2007
- 2007-10-31 US US11/932,777 patent/US20080177046A1/en not_active Abandoned
- 2007-10-31 US US11/933,101 patent/US7833728B2/en not_active Expired - Fee Related
- 2007-10-31 US US11/933,065 patent/US7816493B2/en not_active Expired - Fee Related
-
2008
- 2008-12-22 JP JP2008325146A patent/JP4514820B2/ja not_active Expired - Fee Related
-
2009
- 2009-12-18 JP JP2009288124A patent/JP5199228B2/ja not_active Expired - Fee Related
-
2012
- 2012-11-12 JP JP2012248466A patent/JP5271443B2/ja not_active Expired - Fee Related
-
2014
- 2014-10-30 US US14/529,138 patent/US20150266971A1/en not_active Abandoned
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