AU2003217606C1 - Soluble Form of Carbonic Anhydrase IX (s-CA IX), Assays to Detect s-CA IX, CA IXs Coexpression with HER-2/neu/c-erbB-2 and CA IX-Specific Monoclonal Antibodies to Non-Immunodominant Epitopes - Google Patents

Soluble Form of Carbonic Anhydrase IX (s-CA IX), Assays to Detect s-CA IX, CA IXs Coexpression with HER-2/neu/c-erbB-2 and CA IX-Specific Monoclonal Antibodies to Non-Immunodominant Epitopes Download PDF

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AU2003217606C1
AU2003217606C1 AU2003217606A AU2003217606A AU2003217606C1 AU 2003217606 C1 AU2003217606 C1 AU 2003217606C1 AU 2003217606 A AU2003217606 A AU 2003217606A AU 2003217606 A AU2003217606 A AU 2003217606A AU 2003217606 C1 AU2003217606 C1 AU 2003217606C1
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antigen
antibodies
antibody
amino acid
domain
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AU2003217606B2 (en
AU2003217606A2 (en
AU2003217606A1 (en
AU2003217606B8 (en
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Marta Ortova Gut
Jaromir Pastorek
Silvia Pastorekova
Miriam Zatovicova
Jan Zavada
Zuzanna Zavadova
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Institute of Virology (Slovak Academy of Science)
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Publication of AU2003217606B2 publication Critical patent/AU2003217606B2/en
Priority to AU2008200868A priority Critical patent/AU2008200868B2/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82Translation products from oncogenes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2003217606A 2002-02-21 2003-02-21 Soluble Form of Carbonic Anhydrase IX (s-CA IX), Assays to Detect s-CA IX, CA IXs Coexpression with HER-2/neu/c-erbB-2 and CA IX-Specific Monoclonal Antibodies to Non-Immunodominant Epitopes Ceased AU2003217606C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2008200868A AU2008200868B2 (en) 2002-02-21 2008-02-22 Soluble form of carbonic anhydrase IX (s-CA IX), assays to detect s-CA IX, CA IX's coexpression with HER-2/neu/c-erb-B2, and CA IX-specific monoclonal antibodies to non-immunodominant epitopes

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US35882402P 2002-02-21 2002-02-21
US60/358,824 2002-02-21
US38306802P 2002-05-23 2002-05-23
US60/383,068 2002-05-23
US43149902P 2002-12-05 2002-12-05
US60/431,499 2002-12-05
PCT/US2003/005136 WO2003100029A2 (en) 2002-02-21 2003-02-21 Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use

Related Child Applications (1)

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AU2008200868A Division AU2008200868B2 (en) 2002-02-21 2008-02-22 Soluble form of carbonic anhydrase IX (s-CA IX), assays to detect s-CA IX, CA IX's coexpression with HER-2/neu/c-erb-B2, and CA IX-specific monoclonal antibodies to non-immunodominant epitopes

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AU2003217606A2 AU2003217606A2 (en) 2003-12-12
AU2003217606A1 AU2003217606A1 (en) 2003-12-12
AU2003217606B8 AU2003217606B8 (en) 2003-12-12
AU2003217606B2 AU2003217606B2 (en) 2007-11-22
AU2003217606C1 true AU2003217606C1 (en) 2008-07-17

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AU2003217606A Ceased AU2003217606C1 (en) 2002-02-21 2003-02-21 Soluble Form of Carbonic Anhydrase IX (s-CA IX), Assays to Detect s-CA IX, CA IXs Coexpression with HER-2/neu/c-erbB-2 and CA IX-Specific Monoclonal Antibodies to Non-Immunodominant Epitopes

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US (5) US7846673B2 (enExample)
EP (1) EP1487972B1 (enExample)
JP (4) JP4488351B2 (enExample)
AU (1) AU2003217606C1 (enExample)
CA (1) CA2477163C (enExample)
DK (2) DK1487972T3 (enExample)
HK (1) HK1226095B (enExample)
HU (3) HUE026218T2 (enExample)
WO (1) WO2004005348A1 (enExample)

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JP5199228B2 (ja) 2013-05-15
CA2477163C (en) 2010-07-27
US7833728B2 (en) 2010-11-16
JP2013060452A (ja) 2013-04-04
JP2005535601A (ja) 2005-11-24
AU2003217606B2 (en) 2007-11-22
HUE036891T2 (hu) 2018-08-28
EP1487972A2 (en) 2004-12-22
US20080177046A1 (en) 2008-07-24
EP1487972B1 (en) 2015-08-12
WO2004005348A1 (en) 2004-01-15
JP4488351B2 (ja) 2010-06-23
US20080176258A1 (en) 2008-07-24
EP1487972A4 (en) 2006-05-31
AU2003217606A2 (en) 2003-12-12
US7816493B2 (en) 2010-10-19
HK1177474A1 (en) 2013-08-23
JP4514820B2 (ja) 2010-07-28
AU2003217606A1 (en) 2003-12-12
CA2477163A1 (en) 2003-12-04
HUE026218T2 (en) 2016-05-30
HK1226095B (en) 2017-09-22
JP5271443B2 (ja) 2013-08-21
DK3031910T3 (en) 2017-10-23
US20080176310A1 (en) 2008-07-24
JP2010111679A (ja) 2010-05-20
JP2009114198A (ja) 2009-05-28
AU2003217606B8 (en) 2003-12-12
HUE026277T2 (en) 2016-05-30
US7846673B2 (en) 2010-12-07
US20050031623A1 (en) 2005-02-10
DK1487972T3 (en) 2015-10-19
US20150266971A1 (en) 2015-09-24

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Free format text: IN VOL 21, NO 46, PAGE(S) 5317 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX UNDER THE NAME INSTITUTE OF VIROLOGY, APPLICATION NO. 2003217606, UNDER INID (72), CORRECT THE INVENTION TITLE TO READ MN/ CA IX-SPECIFIC MONOCLONAL ANTIBODIES GENERATED FROM MN/CA IXDEFICIENT MICE METHODS OF USE AND UNDER INID (30), CORRECT THE PRIORITY DATA TO READ 60/358,824 US 21 FEB 2002, 60/431,499 US 5 DEC 2002 AND 60/383,068 US 23 MAY 2002

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Free format text: IN VOL 21, NO 46, PAGE(S) 5317 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX UNDER THE NAME INSTITUTE OF VIROLOGY, APPLICATION NO. 2003217606, UNDER INID (54), CORRECT THE INVENTION TITLE TO READ SOLUBLE FORM OF CARBONIC ANHYDRASE IX (S-CA IX), ASSAYS TO DETECT S-CA IX, CA IXS COEXPRESSION WITH HER-2/NUE/C-ERBB-2 AND CA IX-SPECIFIC MONOCLONAL ANTIBODIES TO NON-IMMUNODOMINANT EPITOPES

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Free format text: IN VOL 21, NO 46, PAGE(S) 5317 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX UNDER THE NAME INSTITUTE OF VIROLOGY, APPLICATION NO. 2003217606, UNDER INID (54), CORRECT THE INVENTION TITLE TO READ SOLUBLE FORM OF CARBONIC ANHYDRASE IX (S-CA IX), ASSAYS TO DETECT S-CA IX, CA IXS COEXPRESSION WITH HER-2/NEU/C-ERBB-2 AND CA IX-SPECIFIC MONOCLONAL ANTIBODIES TO NON-IMMUNODOMINANT EPITOPES

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Free format text: IN VOL 21, NO 46, PAGE(S) 5317 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX UNDER THE NAME INSTITUTE OF VIROLOGY, APPLICATION NUMBER 2003217606, UNDER INID (72), CORRECT THE INVENTORS NAMES TO READ ZAVADA, JAN; PASTOREK, JAROMIR; ZATOVICOVA, MIRIAM; ZAVADOVA, ZUZANNA; ORTOVA GUT, MARTA; PASTOREKOVA, SILVIA

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Free format text: IN VOL 21, NO 46, PAGE(S) 5317 UNDER THE HEADING APPLICATIONS ACCEPTED -NAME INDEX UNDER THE NAME INSTITUTE OF VIROLOGY, APPLICATION NO. 2003217606, U NDER INID (22), CORRECT THE DATE OF FILING APPLICATION TO 21 FEBRUARY 2003

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