AU2008357729A1 - Antibodies against extracellular domain 2 and 3 of HER2 - Google Patents

Antibodies against extracellular domain 2 and 3 of HER2 Download PDF

Info

Publication number
AU2008357729A1
AU2008357729A1 AU2008357729A AU2008357729A AU2008357729A1 AU 2008357729 A1 AU2008357729 A1 AU 2008357729A1 AU 2008357729 A AU2008357729 A AU 2008357729A AU 2008357729 A AU2008357729 A AU 2008357729A AU 2008357729 A1 AU2008357729 A1 AU 2008357729A1
Authority
AU
Australia
Prior art keywords
cancer
affinity ligand
her2
amino acid
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2008357729A
Other languages
English (en)
Other versions
AU2008357729A8 (en
Inventor
Johan Rockberg
Mathias Uhlen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Atlas Therapeutics AB
Original Assignee
Atlas Antibodies AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atlas Antibodies AB filed Critical Atlas Antibodies AB
Publication of AU2008357729A1 publication Critical patent/AU2008357729A1/en
Publication of AU2008357729A8 publication Critical patent/AU2008357729A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2008357729A 2008-06-13 2008-12-12 Antibodies against extracellular domain 2 and 3 of HER2 Abandoned AU2008357729A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2008155676A JP2010006705A (ja) 2008-06-13 2008-06-13 Her2サブセット
JP2008-155676 2008-06-13
US7635208P 2008-06-27 2008-06-27
US61/076352 2008-06-27
PCT/SE2008/000694 WO2009151356A1 (en) 2008-06-13 2008-12-12 Antibodies against extracellular domains 2 and 3 or her2

Publications (2)

Publication Number Publication Date
AU2008357729A1 true AU2008357729A1 (en) 2009-12-17
AU2008357729A8 AU2008357729A8 (en) 2011-02-03

Family

ID=40427661

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008357729A Abandoned AU2008357729A1 (en) 2008-06-13 2008-12-12 Antibodies against extracellular domain 2 and 3 of HER2

Country Status (8)

Country Link
US (1) US20110158988A1 (enExample)
EP (1) EP2294088A1 (enExample)
JP (1) JP2010006705A (enExample)
KR (2) KR20130026418A (enExample)
CN (1) CN102099376A (enExample)
AU (1) AU2008357729A1 (enExample)
CA (1) CA2727941A1 (enExample)
WO (1) WO2009151356A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101759209B1 (ko) 2010-01-22 2017-07-19 성균관대학교산학협력단 Her-2 과발현 유방암 세포 또는 조직에 특이적으로 결합할 수 있는 핵산 압타머 및 그 용도
US8609095B2 (en) 2010-03-04 2013-12-17 Symphogen A/S Anti-HER2 antibodies and compositions
AU2016201799B2 (en) * 2010-05-27 2017-09-07 Genmab A/S Monoclonal antibodies aganst HER2 epitope
CA3051311A1 (en) * 2010-05-27 2011-12-01 Genmab A/S Monoclonal antibodies against her2
EP2575880B1 (en) * 2010-05-27 2019-01-16 Genmab A/S Monoclonal antibodies against her2 epitope
JP2014514314A (ja) 2011-04-20 2014-06-19 ゲンマブ エー/エス Her2およびcd3に対する二重特異性抗体
CN105017425B (zh) * 2014-04-30 2018-02-16 京天成生物技术(北京)有限公司 抗her2中和活性单克隆抗体及其应用
JP6971319B2 (ja) 2016-12-28 2021-11-24 グリーン・クロス・ラブ・セル・コーポレイション キメラ抗原受容体及びそれを発現するナチュラルキラー細胞
EP3712178A4 (en) 2017-11-14 2021-08-11 Green Cross Lab Cell Corporation ANTI-HER2 ANTIBODIES OR ANTIGIBODY FRAGMENT THEREOF AND CHIMERAIR ANTIGEN RECEPTOR WITH IT
US11649294B2 (en) 2017-11-14 2023-05-16 GC Cell Corporation Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
AU2018383096A1 (en) * 2017-12-11 2020-06-11 Medizinische Universitaet Wien A method of producing a vaccine composition and uses thereof
WO2020036869A1 (en) 2018-08-16 2020-02-20 Emd Millipore Corporation Closed bioprocessing device
US20210238305A1 (en) * 2019-03-01 2021-08-05 Remegen Co., Ltd. Antibody for her2 concomitant diagnosis immunohistochemical detection and application thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US6514942B1 (en) * 1995-03-14 2003-02-04 The Board Of Regents, The University Of Texas System Methods and compositions for stimulating T-lymphocytes
US5783404A (en) * 1995-04-13 1998-07-21 Amgen Inc. Methods and compositions for determining HER-2/neu expression using monoclonal antibodies
EP1239866A4 (en) * 1999-12-10 2005-02-09 Epimmune Inc INDUCTION OF HER2 / NEU CELLULAR IMMUNE RESPONSES USING PEPTIDE AND NUCLEIC ACID-CONTAINING COMPOSITIONS
IL159177A0 (en) * 2001-06-20 2004-06-01 Prochon Biotech Ltd Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
CN1136917C (zh) * 2001-10-10 2004-02-04 北京迪威华宇生物技术有限公司 一种卡介苗热休克蛋白65和多表位her-2抗原融合蛋白重组蛋白疫苗
AU2003296330A1 (en) * 2002-12-10 2004-06-30 Epimmune Inc. Hla-a1, a2 -a3,-a24,-b7,and -b44 tumor associated antigen peptides and compositions
US7767792B2 (en) * 2004-02-20 2010-08-03 Ludwig Institute For Cancer Research Ltd. Antibodies to EGF receptor epitope peptides
SV2006002143A (es) * 2004-06-16 2006-01-26 Genentech Inc Uso de un anticuerpo para el tratamiento del cancer resistente al platino
AU2005287404B2 (en) * 2004-07-22 2009-05-07 Genentech, Inc. HER2 antibody composition
ES2348312T3 (es) * 2006-04-13 2010-12-02 Bio Life Science Forschungs- Und Entwicklungsges.M.B.H. Vacuna her-2/neu a base de múltiples péptidos.
CA2655205A1 (en) * 2006-06-12 2007-12-21 Receptor Biologix Inc. Pan-cell surface receptor- specific therapeutics
CN101165068B (zh) * 2006-10-18 2011-09-21 上海复旦张江生物医药股份有限公司 抗HER2/ErbB2抗原的单克隆抗体及其制备方法和药物组合物

Also Published As

Publication number Publication date
WO2009151356A1 (en) 2009-12-17
CN102099376A (zh) 2011-06-15
AU2008357729A8 (en) 2011-02-03
US20110158988A1 (en) 2011-06-30
CA2727941A1 (en) 2009-12-17
KR20110036534A (ko) 2011-04-07
JP2010006705A (ja) 2010-01-14
KR20130026418A (ko) 2013-03-13
EP2294088A1 (en) 2011-03-16

Similar Documents

Publication Publication Date Title
US20110158988A1 (en) Antibodies against extracellular domains 2 and 3 or her2
US20240343824A1 (en) Binding molecules that inhibit cancer growth
JP6823094B2 (ja) Ror1癌の治療および転移の阻害に使用するための抗体およびワクチン
ES2826774T3 (es) Anticuerpo que se une a ERBB-2 y ERBB-3
DK2494359T3 (en) PODXL protein in colorectal cancer
TW201713684A (zh) 用於對抗食道癌及其他癌症的新穎胜肽及胜肽的組合物
MX2012011234A (es) Anticuerpos contra csf-1r.
EP2396346B1 (en) Rbm3 protein in colorectal cancer prognostics
Kim et al. Generation of a human antibody that inhibits TSPAN8-mediated invasion of metastatic colorectal cancer cells
EP3541423A1 (en) Engineered antibodies and uses thereof
US20250122303A1 (en) Treatment and prevention of cancer using her3 antigen-binding molecules
CN112812179B (zh) 高亲和力高特异性抗cmtm6单克隆抗体及其用途
CN112823168A (zh) 结合her2的四聚体多肽
HK40062651A (en) Binding molecules that inhibit cancer growth
HK40051469A (en) Her2-binding tetrameric polypeptides
Panke Fakultät für Chemie Lehrstuhl für Biotechnologie
BR122025017078A2 (pt) Moléculas de ligação que inibem o crescimento do câncer
HK1253914B (en) Binding molecules that inhibit cancer growth

Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ ANTIBODIES AGAINST EXTRACELLULAR DOMAIN 2 AND 3 OF HER2

TH Corrigenda

Free format text: IN VOL 25, NO 4, PAGE(S) 396 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME ATLAS ANTIBODIES AB, APPLICATION NO. 2008357729, UNDER INID (71) CORRECT THE APPLICANT NAME TO ATLAS THERAPEUTICS AB

MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period