JP2009544333A5 - - Google Patents
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- JP2009544333A5 JP2009544333A5 JP2009522035A JP2009522035A JP2009544333A5 JP 2009544333 A5 JP2009544333 A5 JP 2009544333A5 JP 2009522035 A JP2009522035 A JP 2009522035A JP 2009522035 A JP2009522035 A JP 2009522035A JP 2009544333 A5 JP2009544333 A5 JP 2009544333A5
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- Prior art keywords
- seq
- sequence
- homology
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000012634 fragment Substances 0.000 claims description 277
- 239000002773 nucleotide Substances 0.000 claims description 235
- 125000003729 nucleotide group Chemical group 0.000 claims description 235
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 133
- 102000039446 nucleic acids Human genes 0.000 claims description 59
- 108020004707 nucleic acids Proteins 0.000 claims description 59
- 150000007523 nucleic acids Chemical class 0.000 claims description 59
- 108090000623 proteins and genes Proteins 0.000 claims description 53
- 102000004169 proteins and genes Human genes 0.000 claims description 53
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 29
- 239000000203 mixture Substances 0.000 claims description 15
- 108010008038 Synthetic Vaccines Proteins 0.000 claims description 12
- 229940124551 recombinant vaccine Drugs 0.000 claims description 12
- 230000028993 immune response Effects 0.000 claims description 11
- 230000001939 inductive effect Effects 0.000 claims description 11
- 239000008194 pharmaceutical composition Substances 0.000 claims description 8
- 230000002238 attenuated effect Effects 0.000 claims description 6
- 244000052769 pathogen Species 0.000 claims description 6
- 230000001717 pathogenic effect Effects 0.000 claims description 5
- 206010046865 Vaccinia virus infection Diseases 0.000 claims description 4
- 229960005486 vaccine Drugs 0.000 claims description 4
- 208000007089 vaccinia Diseases 0.000 claims description 4
- 239000013612 plasmid Substances 0.000 claims description 2
- 150000001413 amino acids Chemical class 0.000 claims 1
- 206010022000 influenza Diseases 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83385606P | 2006-07-28 | 2006-07-28 | |
| US83386106P | 2006-07-28 | 2006-07-28 | |
| US89035207P | 2007-02-16 | 2007-02-16 | |
| PCT/US2007/074769 WO2008014521A2 (en) | 2006-07-28 | 2007-07-30 | Improved vaccines and methods for using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013019415A Division JP6097086B2 (ja) | 2006-07-28 | 2013-02-04 | 改良されたワクチンおよびそれを使用するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009544333A JP2009544333A (ja) | 2009-12-17 |
| JP2009544333A5 true JP2009544333A5 (https=) | 2011-09-01 |
Family
ID=38982433
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009522035A Pending JP2009544333A (ja) | 2006-07-28 | 2007-07-30 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2013019415A Active JP6097086B2 (ja) | 2006-07-28 | 2013-02-04 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2014208626A Active JP6186333B2 (ja) | 2006-07-28 | 2014-10-10 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2015225411A Active JP6356653B2 (ja) | 2006-07-28 | 2015-11-18 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2018043805A Withdrawn JP2018108110A (ja) | 2006-07-28 | 2018-03-12 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2020044718A Withdrawn JP2020103318A (ja) | 2006-07-28 | 2020-03-13 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2020044717A Active JP7030347B2 (ja) | 2006-07-28 | 2020-03-13 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2022045506A Ceased JP2022081665A (ja) | 2006-07-28 | 2022-03-22 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2024204927A Pending JP2025032154A (ja) | 2006-07-28 | 2024-11-25 | 改良されたワクチンおよびそれを使用するための方法 |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013019415A Active JP6097086B2 (ja) | 2006-07-28 | 2013-02-04 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2014208626A Active JP6186333B2 (ja) | 2006-07-28 | 2014-10-10 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2015225411A Active JP6356653B2 (ja) | 2006-07-28 | 2015-11-18 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2018043805A Withdrawn JP2018108110A (ja) | 2006-07-28 | 2018-03-12 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2020044718A Withdrawn JP2020103318A (ja) | 2006-07-28 | 2020-03-13 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2020044717A Active JP7030347B2 (ja) | 2006-07-28 | 2020-03-13 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2022045506A Ceased JP2022081665A (ja) | 2006-07-28 | 2022-03-22 | 改良されたワクチンおよびそれを使用するための方法 |
| JP2024204927A Pending JP2025032154A (ja) | 2006-07-28 | 2024-11-25 | 改良されたワクチンおよびそれを使用するための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US8168769B2 (https=) |
| EP (7) | EP4400510A3 (https=) |
| JP (9) | JP2009544333A (https=) |
| KR (10) | KR101710981B1 (https=) |
| CN (3) | CN105063064B (https=) |
| AU (4) | AU2007278831B2 (https=) |
| CA (4) | CA3057039C (https=) |
| DK (2) | DK2049559T3 (https=) |
| ES (2) | ES2706501T3 (https=) |
| HK (1) | HK1218427A1 (https=) |
| MX (3) | MX346862B (https=) |
| WO (1) | WO2008014521A2 (https=) |
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| CA3057039C (en) * | 2006-07-28 | 2023-02-28 | The Trustees Of The University Of Pennsylvania | Hiv consensus envelope sequences and methods for using same |
| US8926961B2 (en) * | 2007-10-03 | 2015-01-06 | Board Of Trustees Of The University Of Arkansas | HPV E6 protein T cell epitopes and uses thereof |
| CA2705461A1 (en) * | 2007-11-12 | 2009-06-11 | The Trustees Of The University Of Pennsylvania | Vaccines against multiple subtypes of influenza virus |
| CA2653478A1 (en) | 2009-01-23 | 2010-07-23 | Gregg Martin | Automated wash system for industrial vehicles |
| CN102449737A (zh) | 2009-03-02 | 2012-05-09 | 加利福尼亚大学董事会 | 生长于非极性或半极性(Ga，Al，In，B)N衬底上的装置 |
| WO2011032179A1 (en) * | 2009-09-14 | 2011-03-17 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics comprising il-15 receptor alpha and/or nucleic acid molecules encoding the same, and methods for using the same |
| US8298820B2 (en) | 2010-01-26 | 2012-10-30 | The Trustees Of The University Of Pennsylvania | Influenza nucleic acid molecules and vaccines made therefrom |
| EP2539354B1 (en) * | 2010-02-08 | 2017-04-05 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same |
| PL2536830T3 (pl) | 2010-02-16 | 2020-02-28 | Ultimovacs As | Polipeptydy |
| WO2012040101A1 (en) | 2010-09-21 | 2012-03-29 | University Of Miami | Compositions and methods for inducing migration by dendritic cells and an immune response |
| WO2012040266A2 (en) * | 2010-09-24 | 2012-03-29 | University Of Miami | Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines |
| WO2012051211A2 (en) * | 2010-10-11 | 2012-04-19 | Novartis Ag | Antigen delivery platforms |
| MX360449B (es) * | 2011-10-12 | 2018-11-01 | Univ Pennsylvania | Vacunas para el virus del papiloma humano y metodos para su uso. |
| JP6407028B2 (ja) | 2011-12-12 | 2018-10-17 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ＭＲＳＡのＰＢＰ２ａ及びその断片を含むタンパク質、それをコードする核酸、並びにＭＲＳＡ感染を予防する及び治療するための組成物及びそれらの使用 |
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| CN103102394B (zh) * | 2013-02-27 | 2014-06-25 | 北京大学人民医院 | 丙型肝炎病毒b细胞表位肽puhi49及其应用 |
| CN103172705B (zh) * | 2013-02-27 | 2014-08-20 | 北京大学人民医院 | 丙型肝炎病毒b细胞表位肽puhi16及其应用 |
| CN103113458B (zh) * | 2013-02-27 | 2014-08-20 | 北京大学人民医院 | 丙型肝炎病毒b细胞表位肽puhi34及其应用 |
| AU2014248535B2 (en) | 2013-03-12 | 2017-03-30 | Inovio Pharmaceuticals, Inc. | Improved vaccines for human papilloma virus and methods for using the same |
| KR20150130284A (ko) * | 2013-03-15 | 2015-11-23 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 암 백신 및 이를 이용한 치료 방법 |
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| MA40783A (fr) * | 2014-10-03 | 2017-08-08 | Los Alamos Nat Security Llc | Vaccins contre le vih comprenant un ou plusieurs antigènes episensus de population |
| WO2016123285A1 (en) * | 2015-01-29 | 2016-08-04 | The Trustees Of The University Of Pennsylvania | Checkpoint inhibitor and vaccine combinations and use of same for immunotherapy |
| IL260030B2 (en) | 2016-01-08 | 2025-12-01 | Nykode Therapeutics ASA | Therapeutic anticancer neoepitope vaccine |
| WO2017136758A1 (en) * | 2016-02-05 | 2017-08-10 | Inovio Pharmaceuticals, Inc. | Cancer vaccines and methods of treatment using the same |
| CN109069575A (zh) * | 2016-02-23 | 2018-12-21 | 毛里齐奥·扎内蒂 | 通用癌症疫苗 |
| EP3518955A4 (en) | 2016-09-30 | 2020-10-07 | The Wistar Institute Of Anatomy And Biology | TERT-IMMUNOGENIC COMPOSITIONS AND METHODS OF TREATMENT THEREOF |
| CN110418648B (zh) * | 2017-02-22 | 2023-09-08 | 丁恩雨 | 一种编码人GM-CSF与多串连表位融合的mRNA癌症疫苗 |
| CN109142723B (zh) * | 2018-08-21 | 2021-07-13 | 苏州华益美生物科技有限公司 | 人类免疫缺陷病毒快速检测测试卡及其应用 |
| KR20240137107A (ko) | 2019-07-16 | 2024-09-19 | 길리애드 사이언시즈, 인코포레이티드 | Hiv 백신, 및 이의 제조 및 사용 방법 |
| WO2021202949A2 (en) * | 2020-04-02 | 2021-10-07 | Inovio Pharmaceuticals, Inc. | Compositions and methods for treating vulvar dysplasia |
| US12053517B2 (en) | 2021-01-14 | 2024-08-06 | Gilead Sciences, Inc. | HIV vaccines and methods of using |
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| CA2664168A1 (en) * | 2006-10-12 | 2008-04-17 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa | Telomerase reverse transcriptase fusion protein, nucleotides encoding it, and uses thereof |
| GB2504774A (en) | 2012-08-10 | 2014-02-12 | Munster Simms Eng Ltd | Diaphragm pump with integral motor housing and rear pump housing |
| KR20140137679A (ko) | 2013-05-23 | 2014-12-03 | 삼성전자주식회사 | 카드 소켓 장치 |
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