JP2009543567A5 - - Google Patents
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- Publication number
- JP2009543567A5 JP2009543567A5 JP2009519869A JP2009519869A JP2009543567A5 JP 2009543567 A5 JP2009543567 A5 JP 2009543567A5 JP 2009519869 A JP2009519869 A JP 2009519869A JP 2009519869 A JP2009519869 A JP 2009519869A JP 2009543567 A5 JP2009543567 A5 JP 2009543567A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- stretch
- nucleotides
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002773 nucleotide Substances 0.000 claims 75
- 125000003729 nucleotide group Chemical group 0.000 claims 74
- 150000007523 nucleic acids Chemical class 0.000 claims 73
- 108020004707 nucleic acids Proteins 0.000 claims 68
- 102000039446 nucleic acids Human genes 0.000 claims 68
- 101710088580 Stromal cell-derived factor 1 Proteins 0.000 claims 26
- 102100021669 Stromal cell-derived factor 1 Human genes 0.000 claims 26
- 239000005557 antagonist Substances 0.000 claims 12
- 239000000556 agonist Substances 0.000 claims 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 238000009396 hybridization Methods 0.000 claims 3
- 239000000470 constituent Substances 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 238000012986 modification Methods 0.000 claims 2
- 230000004048 modification Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 claims 1
- 101710082513 C-X-C chemokine receptor type 4 Proteins 0.000 claims 1
- 101000617130 Homo sapiens Stromal cell-derived factor 1 Proteins 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 102000043525 human CXCL12 Human genes 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06014957.2 | 2006-07-18 | ||
| EP06014957 | 2006-07-18 | ||
| PCT/EP2007/006387 WO2008009437A2 (en) | 2006-07-18 | 2007-07-18 | Sdf-i binding nucleic acids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009543567A JP2009543567A (ja) | 2009-12-10 |
| JP2009543567A5 true JP2009543567A5 (https=) | 2010-09-02 |
| JP5380287B2 JP5380287B2 (ja) | 2014-01-08 |
Family
ID=38947372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519869A Active JP5380287B2 (ja) | 2006-07-18 | 2007-07-18 | Ｓｄｆ−１結合核酸 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8314223B2 (https=) |
| EP (1) | EP2041282B1 (https=) |
| JP (1) | JP5380287B2 (https=) |
| KR (2) | KR101561652B1 (https=) |
| CN (2) | CN101506364B (https=) |
| AR (1) | AR061929A1 (https=) |
| AU (1) | AU2007276435C1 (https=) |
| BR (1) | BRPI0714844B8 (https=) |
| CA (1) | CA2658267C (https=) |
| DK (1) | DK2041282T3 (https=) |
| ES (1) | ES2663404T3 (https=) |
| MX (1) | MX2009000656A (https=) |
| PL (1) | PL2041282T3 (https=) |
| PT (1) | PT2041282T (https=) |
| RU (1) | RU2590709C2 (https=) |
| WO (1) | WO2008009437A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2590709C2 (ru) | 2006-07-18 | 2016-07-10 | Ноксон Фарма Аг | Sdf-1-связывающие нуклеиновые кислоты |
| KR101589442B1 (ko) * | 2007-08-06 | 2016-02-01 | 녹손 파르마 아게 | 에스디에프-1 결합형 핵산 및 이의 용도 |
| JP5463621B2 (ja) | 2008-02-27 | 2014-04-09 | ソニー株式会社 | 標的物質の定量方法 |
| WO2009149921A2 (en) * | 2008-06-11 | 2009-12-17 | Bionucleon S.R.L. | Inhibition of hrp-3 using modified oligonucleotides |
| TWI578992B (zh) | 2009-04-30 | 2017-04-21 | 諾克森製藥股份有限公司 | 與鐵調節激素（ｈｅｐｃｉｄｉｎ）結合之核酸類 |
| WO2012025251A1 (en) * | 2010-08-27 | 2012-03-01 | Noxxon Pharma Ag | Nucleic acids for treatment of chronic complications of diabetes |
| US20130310442A1 (en) | 2010-09-09 | 2013-11-21 | Noxxon Pharma Ag | SDF-1 Binding Nucleic Acids and the use Thereof in Cancer Treatment |
| WO2012055573A1 (en) * | 2010-10-29 | 2012-05-03 | Noxxon Pharma Ag | Use of hepcidin binding nucleic acids for depletion of hepcidin from the body |
| JP6453212B2 (ja) | 2012-07-13 | 2019-01-16 | ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． | キラル制御 |
| US10647766B2 (en) * | 2014-12-17 | 2020-05-12 | Cancer Research Technology Limited | Anti-CXCL12 antibody molecules and their uses |
| WO2017178119A1 (en) * | 2016-04-15 | 2017-10-19 | Noxxon Pharma Ag | Method of modulating the number and the distribution of tumor-infiltrating leukocytes in tumors |
| US11221270B2 (en) * | 2018-02-27 | 2022-01-11 | Kevan M Evans | Method and apparatus for detecting slow leaks |
| WO2021178923A1 (en) | 2020-03-06 | 2021-09-10 | Drinksavvy, Inc. | Devices and methods for detecting a target analyte of interest |
| EP4173639A4 (en) | 2020-06-26 | 2024-03-13 | RaQualia Pharma Inc. | METHOD FOR SELECTING A CANCER PATIENT FOR WHICH COMBINATION THERAPY OF A RETINOID AND A CANCER TREATMENT AGENT WILL BE EFFECTIVE, AND COMBINATION DRUG OF A RETINOID AND A CANCER TREATMENT AGENT |
| WO2023154452A1 (en) | 2022-02-11 | 2023-08-17 | Waypoint Bio, Inc. | Cellular staining probes for analyte detection |
| TW202430127A (zh) * | 2023-01-19 | 2024-08-01 | 國立陽明交通大學 | 可用於遞送內質網壓力誘導劑或免疫療法的複合奈米粒及其用途 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| CA2104698A1 (en) * | 1991-02-21 | 1992-08-22 | John J. Toole | Aptamers specific for biomolecules and methods of making |
| US5840867A (en) | 1991-02-21 | 1998-11-24 | Gilead Sciences, Inc. | Aptamer analogs specific for biomolecules |
| US5582981A (en) | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
| EP1745797A3 (en) | 1998-03-24 | 2007-07-18 | Chugai Seiyaku Kabushiki Kaisha | Vascularization inhibitors |
| US6670149B1 (en) * | 1999-03-01 | 2003-12-30 | Millennium Pharmaceuticals, Inc. | TWIK-5 potassium channel nucleic acids and uses therefor |
| US6949243B1 (en) | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
| EP1133988A1 (en) * | 2000-03-11 | 2001-09-19 | Biognostik Gesellschaft für biomolekulare Diagnostik mbH | Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene |
| US7468253B2 (en) | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
| JP4233092B2 (ja) | 2001-06-07 | 2009-03-04 | ケモセントリックス， インコーポレイテッド | 細胞移動アッセイ |
| GB0225833D0 (en) | 2002-11-06 | 2002-12-11 | Univ Leeds | Nucleic acid ligands and uses therefor |
| ES2729826T3 (es) | 2004-09-23 | 2019-11-06 | Arc Medical Devices Inc | Composiciones farmacéuticas y métodos relacionados para inhibir adherencias fibrosas o enfermedad inflamatoria usando fucanos con bajo contenido de sulfato |
| EP1817414B1 (de) * | 2004-11-29 | 2010-07-14 | Noxxon Pharma AG | Vasopressin bindende l-nukleinsäure |
| EP2397148A3 (en) | 2006-02-02 | 2012-04-25 | Allergan, Inc. | Compositions and methods for the treatment of ophthalmic disease |
| RU2590709C2 (ru) | 2006-07-18 | 2016-07-10 | Ноксон Фарма Аг | Sdf-1-связывающие нуклеиновые кислоты |
| KR101722261B1 (ko) | 2006-10-02 | 2017-04-03 | 메다렉스, 엘.엘.시. | Ｃｘｃｒ4에 결합하는 인간 항체 및 이의 용도 |
| AU2007325029B2 (en) | 2006-11-30 | 2013-09-12 | The Regents Of The University Of California | Methods for treating and diagnosing fibrotic and fibroproliferative diseases |
| KR101589442B1 (ko) | 2007-08-06 | 2016-02-01 | 녹손 파르마 아게 | 에스디에프-1 결합형 핵산 및 이의 용도 |
| US20090274687A1 (en) | 2008-05-02 | 2009-11-05 | University Of Miami | Attenuation of hypoxia induced cardiovascular disorders |
-
2007
- 2007-07-18 RU RU2009105494/10A patent/RU2590709C2/ru active
- 2007-07-18 BR BRPI0714844A patent/BRPI0714844B8/pt active IP Right Grant
- 2007-07-18 MX MX2009000656A patent/MX2009000656A/es active IP Right Grant
- 2007-07-18 AR ARP070103212A patent/AR061929A1/es active IP Right Grant
- 2007-07-18 ES ES07786160.7T patent/ES2663404T3/es active Active
- 2007-07-18 KR KR1020137020754A patent/KR101561652B1/ko active Active
- 2007-07-18 EP EP07786160.7A patent/EP2041282B1/en active Active
- 2007-07-18 DK DK07786160.7T patent/DK2041282T3/en active
- 2007-07-18 JP JP2009519869A patent/JP5380287B2/ja active Active
- 2007-07-18 PT PT77861607T patent/PT2041282T/pt unknown
- 2007-07-18 KR KR1020097000923A patent/KR101466931B1/ko active Active
- 2007-07-18 CN CN2007800305243A patent/CN101506364B/zh active Active
- 2007-07-18 CN CN201310486348.1A patent/CN103555725B/zh active Active
- 2007-07-18 CA CA2658267A patent/CA2658267C/en active Active
- 2007-07-18 WO PCT/EP2007/006387 patent/WO2008009437A2/en not_active Ceased
- 2007-07-18 AU AU2007276435A patent/AU2007276435C1/en active Active
- 2007-07-18 PL PL07786160T patent/PL2041282T3/pl unknown
-
2009
- 2009-01-18 US US12/374,311 patent/US8314223B2/en active Active
-
2012
- 2012-10-13 US US13/651,385 patent/US9035038B2/en active Active
-
2015
- 2015-05-06 US US14/705,809 patent/US9822369B2/en active Active
-
2017
- 2017-11-20 US US15/818,618 patent/US20180163207A1/en not_active Abandoned
-
2020
- 2020-11-09 US US17/092,390 patent/US20210139909A1/en not_active Abandoned
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