BRPI0807251A2 - "método de tratamento de uma condição inflamatória em um indivíduo com necessidade do mesmo, método de seleção de um indivíduo para o tratamento ou não de uma condição inflamátoria com um agente anti-inflamatório ou um agente anticoagulante, método de seleção de um grupo de indivíduos para determinar a eficácia de uma droga candidata conhecida ou sespeita de ser útil para o tratamento de uma condição inflamatória, método para aumentar a probabilidade da eficácia de um tratamento com proteína c ou um tratamento com um compsoto similar à proteína c, método para identificar um indivíduo que tem um ou mais genótipo(s) de evento adverso grave, de resposta melhorada, de risco ou de evento adverso grave reduzido, uso de um agente anti-inflamatório ou um agente anticoagulante na manufatura de um medicamento para tratamento de uma condição inflamatória em um subconjunto de indivíduos, pacote comercial, dois ou mais oligonucleotídeos ou ácidos nucléicos de peptídeos de aproximadamente 10 a aproximadamente 400 nucleotídeos, disposição de oligonucleotídeos ou ácidos nucléicos de peptídeos unidos a um suporte sólido e composição" - Google Patents
"método de tratamento de uma condição inflamatória em um indivíduo com necessidade do mesmo, método de seleção de um indivíduo para o tratamento ou não de uma condição inflamátoria com um agente anti-inflamatório ou um agente anticoagulante, método de seleção de um grupo de indivíduos para determinar a eficácia de uma droga candidata conhecida ou sespeita de ser útil para o tratamento de uma condição inflamatória, método para aumentar a probabilidade da eficácia de um tratamento com proteína c ou um tratamento com um compsoto similar à proteína c, método para identificar um indivíduo que tem um ou mais genótipo(s) de evento adverso grave, de resposta melhorada, de risco ou de evento adverso grave reduzido, uso de um agente anti-inflamatório ou um agente anticoagulante na manufatura de um medicamento para tratamento de uma condição inflamatória em um subconjunto de indivíduos, pacote comercial, dois ou mais oligonucleotídeos ou ácidos nucléicos de peptídeos de aproximadamente 10 a aproximadamente 400 nucleotídeos, disposição de oligonucleotídeos ou ácidos nucléicos de peptídeos unidos a um suporte sólido e composição"Info
- Publication number
- BRPI0807251A2 BRPI0807251A2 BRPI0807251A BRPI0807251A BRPI0807251A2 BR PI0807251 A2 BRPI0807251 A2 BR PI0807251A2 BR PI0807251 A BRPI0807251 A BR PI0807251A BR PI0807251 A BRPI0807251 A BR PI0807251A BR PI0807251 A2 BRPI0807251 A2 BR PI0807251A2
- Authority
- BR
- Brazil
- Prior art keywords
- inflammatory condition
- treating
- individual
- treatment
- inflammatory
- Prior art date
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
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- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90167207P | 2007-02-16 | 2007-02-16 | |
US90718807P | 2007-03-23 | 2007-03-23 | |
PCT/CA2008/000305 WO2008098377A1 (en) | 2007-02-16 | 2008-02-18 | Serpine1 polymorphisms are predictive of response to activated protein c administration and risk of death |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0807251A2 true BRPI0807251A2 (pt) | 2019-09-24 |
Family
ID=39689599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0807251A BRPI0807251A2 (pt) | 2007-02-16 | 2008-02-18 | "método de tratamento de uma condição inflamatória em um indivíduo com necessidade do mesmo, método de seleção de um indivíduo para o tratamento ou não de uma condição inflamátoria com um agente anti-inflamatório ou um agente anticoagulante, método de seleção de um grupo de indivíduos para determinar a eficácia de uma droga candidata conhecida ou sespeita de ser útil para o tratamento de uma condição inflamatória, método para aumentar a probabilidade da eficácia de um tratamento com proteína c ou um tratamento com um compsoto similar à proteína c, método para identificar um indivíduo que tem um ou mais genótipo(s) de evento adverso grave, de resposta melhorada, de risco ou de evento adverso grave reduzido, uso de um agente anti-inflamatório ou um agente anticoagulante na manufatura de um medicamento para tratamento de uma condição inflamatória em um subconjunto de indivíduos, pacote comercial, dois ou mais oligonucleotídeos ou ácidos nucléicos de peptídeos de aproximadamente 10 a aproximadamente 400 nucleotídeos, disposição de oligonucleotídeos ou ácidos nucléicos de peptídeos unidos a um suporte sólido e composição" |
Country Status (9)
Country | Link |
---|---|
US (1) | US20100209413A1 (pt) |
EP (1) | EP2032748A4 (pt) |
JP (1) | JP2010517585A (pt) |
CN (1) | CN101688327A (pt) |
AU (1) | AU2008215079A1 (pt) |
BR (1) | BRPI0807251A2 (pt) |
CA (1) | CA2678436A1 (pt) |
MX (1) | MX2009008788A (pt) |
WO (1) | WO2008098377A1 (pt) |
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Publication number | Priority date | Publication date | Assignee | Title |
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WO2012068519A2 (en) * | 2010-11-19 | 2012-05-24 | Sirius Genomics Inc. | Markers associated with response to activated protein c administration, and uses thereof |
WO2018057858A1 (en) * | 2016-09-23 | 2018-03-29 | Memorial Sloan Kettering Cancer Center | Determinants of cancer response to immunotherapy |
CN111883258B (zh) * | 2020-04-30 | 2024-03-15 | 浙江大学山东工业技术研究院 | 一种构建ohss分度分型预测模型的方法 |
CN112270994B (zh) * | 2020-10-14 | 2021-08-17 | 中国医学科学院阜外医院 | 一种风险预测模型的构建方法、设备、终端及存储介质 |
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---|---|---|---|---|
US5130423A (en) | 1990-07-13 | 1992-07-14 | Microprobe Corporation | Non-corrosive compositions and methods useful for the extraction of nucleic acids |
US7081360B2 (en) * | 1998-07-28 | 2006-07-25 | Cadus Technologies, Inc. | Expression of G protein-coupled receptors with altered ligand binding and/or coupling properties |
AU2003233292A1 (en) * | 2002-05-28 | 2003-12-12 | The University Of British Columbia | Protein c polymorphisms |
US20060246451A1 (en) * | 2003-03-19 | 2006-11-02 | Russell James A | Plasminogen activator inhibitor-1 (pai-1) haplotypes useful as indicators of patient outcome |
CA2479968A1 (en) * | 2004-09-01 | 2006-03-01 | Keith R. Walley | Protein c and endothelial protein c receptor polymorphisms as indicators of patient outcome |
MX2008009056A (es) * | 2006-01-12 | 2009-01-07 | Univ British Columbia | Polimorfismos asociados con la trayectoria de la proteina c como predictores de la respuesta a la administracion de la proteina c activada a un compuesto similar a la proteina. |
-
2008
- 2008-02-18 EP EP08714628A patent/EP2032748A4/en not_active Withdrawn
- 2008-02-18 CA CA002678436A patent/CA2678436A1/en not_active Abandoned
- 2008-02-18 BR BRPI0807251A patent/BRPI0807251A2/pt not_active IP Right Cessation
- 2008-02-18 US US12/295,232 patent/US20100209413A1/en not_active Abandoned
- 2008-02-18 MX MX2009008788A patent/MX2009008788A/es not_active Application Discontinuation
- 2008-02-18 CN CN200880012061A patent/CN101688327A/zh active Pending
- 2008-02-18 AU AU2008215079A patent/AU2008215079A1/en not_active Abandoned
- 2008-02-18 WO PCT/CA2008/000305 patent/WO2008098377A1/en active Application Filing
- 2008-02-18 JP JP2009549350A patent/JP2010517585A/ja active Pending
Also Published As
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JP2010517585A (ja) | 2010-05-27 |
EP2032748A4 (en) | 2009-11-11 |
US20100209413A1 (en) | 2010-08-19 |
EP2032748A1 (en) | 2009-03-11 |
CN101688327A (zh) | 2010-03-31 |
WO2008098377A1 (en) | 2008-08-21 |
MX2009008788A (es) | 2009-08-24 |
CA2678436A1 (en) | 2008-08-21 |
AU2008215079A1 (en) | 2008-08-21 |
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