JP2009541443A - 尿失禁及び関連疾患の治療のためのフリバンセリン - Google Patents
尿失禁及び関連疾患の治療のためのフリバンセリン Download PDFInfo
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- JP2009541443A JP2009541443A JP2009517186A JP2009517186A JP2009541443A JP 2009541443 A JP2009541443 A JP 2009541443A JP 2009517186 A JP2009517186 A JP 2009517186A JP 2009517186 A JP2009517186 A JP 2009517186A JP 2009541443 A JP2009541443 A JP 2009541443A
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- pharmaceutically acceptable
- solvate
- hydrate
- acid addition
- active ingredient
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| EP06116393 | 2006-06-30 | ||
| PCT/EP2007/056400 WO2008000760A1 (en) | 2006-06-30 | 2007-06-27 | Flibanserin for the treatment of urinary incontinence and related diseases |
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| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US20040048877A1 (en) * | 2002-05-22 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions containing flibanserin |
| US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
| EP1912650B8 (en) * | 2005-08-03 | 2017-10-18 | Sprout Pharmaceuticals, Inc. | Use of flibanserin in the treatment of obesity |
| EP1945214A1 (en) | 2005-10-29 | 2008-07-23 | Boehringer Ingelheim International GmbH | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| PT2021006E (pt) * | 2006-05-09 | 2015-11-12 | Sprout Pharmaceuticals Inc | Uso de flibanserina para o tratamento de distúrbios de desejo sexual pós-menopausa |
| JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| KR20090042967A (ko) | 2006-08-14 | 2009-05-04 | 베링거 인겔하임 인터내셔날 게엠베하 | 플리반세린 제형 및 이의 제조방법 |
| CN104721168A (zh) | 2006-08-25 | 2015-06-24 | 贝林格尔·英格海姆国际有限公司 | 控制释放系统及其制造方法 |
| WO2008074795A1 (en) * | 2006-12-20 | 2008-06-26 | Boehringer Ingelheim International Gmbh | Sulfated benzimidazolone derivatives having mixed serotonine receptor affinity |
| WO2008090742A1 (ja) * | 2007-01-23 | 2008-07-31 | National University Corporation Hokkaido University | 眼疾患モデル用非ヒト動物 |
| CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
| CA2686480A1 (en) | 2008-12-15 | 2010-06-15 | Boehringer Ingelheim International Gmbh | New salts |
| US8778998B2 (en) | 2009-04-10 | 2014-07-15 | Auspex Pharmaceuticals, Inc. | Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor |
| US20100291151A1 (en) * | 2009-04-21 | 2010-11-18 | Auspex Pharmaceuticals, Inc. | 1-methylpyrazole modulators of substance p, calcitonin gene-related peptide, adrenergic receptor, and/or 5-ht receptor |
| WO2021028610A2 (es) * | 2019-08-13 | 2021-02-18 | Universidade De Santiago De Compostela | Compuestos y métodos para el tratamiento del cancer |
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| WO2003035072A1 (en) * | 2001-10-20 | 2003-05-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of flibanserin in the treatment of sexual disorders |
| WO2003097058A1 (en) * | 2002-05-22 | 2003-11-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New pharmaceutical compositions containing flibanserin polymorph a |
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2007
- 2007-06-27 JP JP2009517186A patent/JP2009541443A/ja active Pending
- 2007-06-27 CA CA2654798A patent/CA2654798C/en not_active Expired - Fee Related
- 2007-06-27 WO PCT/EP2007/056400 patent/WO2008000760A1/en not_active Ceased
- 2007-06-27 EP EP07765655A patent/EP2037927B1/en not_active Not-in-force
- 2007-06-27 US US12/306,878 patent/US20090312242A1/en not_active Abandoned
- 2007-06-27 AT AT07765655T patent/ATE456369T1/de active
- 2007-06-27 DE DE602007004615T patent/DE602007004615D1/de active Active
- 2007-06-27 ES ES07765655T patent/ES2336719T3/es active Active
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2012
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2015
- 2015-07-27 US US14/809,862 patent/US9763936B2/en not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| ES2336719T3 (es) | 2010-04-15 |
| DE602007004615D1 (de) | 2010-03-18 |
| CA2654798C (en) | 2015-01-13 |
| EP2037927A1 (en) | 2009-03-25 |
| US20180071282A1 (en) | 2018-03-15 |
| CA2654798A1 (en) | 2008-01-03 |
| US9763936B2 (en) | 2017-09-19 |
| WO2008000760A1 (en) | 2008-01-03 |
| US20090312242A1 (en) | 2009-12-17 |
| EP2037927B1 (en) | 2010-01-27 |
| US20160051545A1 (en) | 2016-02-25 |
| US10004731B2 (en) | 2018-06-26 |
| US20130203671A1 (en) | 2013-08-08 |
| ATE456369T1 (de) | 2010-02-15 |
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