JP2009530445A5 - - Google Patents
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- Publication number
- JP2009530445A5 JP2009530445A5 JP2009500563A JP2009500563A JP2009530445A5 JP 2009530445 A5 JP2009530445 A5 JP 2009530445A5 JP 2009500563 A JP2009500563 A JP 2009500563A JP 2009500563 A JP2009500563 A JP 2009500563A JP 2009530445 A5 JP2009530445 A5 JP 2009530445A5
- Authority
- JP
- Japan
- Prior art keywords
- process according
- aqueous liquid
- maintained
- naoh
- dropwise addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 15
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 9
- 239000007788 liquid Substances 0.000 claims 7
- 238000011084 recovery Methods 0.000 claims 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
- HFBMWMNUJJDEQZ-UHFFFAOYSA-N acryloyl chloride Chemical compound ClC(=O)C=C HFBMWMNUJJDEQZ-UHFFFAOYSA-N 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 2
- 229920002674 hyaluronan Polymers 0.000 claims 2
- 229960003160 hyaluronic acid Drugs 0.000 claims 2
- 238000002156 mixing Methods 0.000 claims 2
- 239000008363 phosphate buffer Substances 0.000 claims 2
- 238000001556 precipitation Methods 0.000 claims 2
- 239000000706 filtrate Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 239000000047 product Substances 0.000 claims 1
- 239000011541 reaction mixture Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78258106P | 2006-03-14 | 2006-03-14 | |
| US60/782,581 | 2006-03-14 | ||
| PCT/US2007/063671 WO2007106738A2 (en) | 2006-03-14 | 2007-03-09 | Acrylated hyaluronic acid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009530445A JP2009530445A (ja) | 2009-08-27 |
| JP2009530445A5 true JP2009530445A5 (OSRAM) | 2010-04-22 |
| JP5123285B2 JP5123285B2 (ja) | 2013-01-23 |
Family
ID=37054621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009500563A Expired - Fee Related JP5123285B2 (ja) | 2006-03-14 | 2007-03-09 | アクリル化ヒアルロン酸 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20090118423A1 (OSRAM) |
| EP (1) | EP1999160B1 (OSRAM) |
| JP (1) | JP5123285B2 (OSRAM) |
| CN (1) | CN101405303B (OSRAM) |
| AT (1) | ATE453670T1 (OSRAM) |
| AU (1) | AU2007226690B2 (OSRAM) |
| BR (1) | BRPI0708776A2 (OSRAM) |
| CA (1) | CA2647481A1 (OSRAM) |
| DE (1) | DE602007004086D1 (OSRAM) |
| DK (1) | DK1999160T3 (OSRAM) |
| ES (1) | ES2339181T3 (OSRAM) |
| PL (1) | PL1999160T3 (OSRAM) |
| WO (1) | WO2007106738A2 (OSRAM) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101100803B1 (ko) * | 2009-04-24 | 2011-12-29 | 서울과학기술대학교 산학협력단 | 리포아마이드가 결합된 고분자화합물과 이의 제조방법 |
| JP2014515426A (ja) * | 2011-05-30 | 2014-06-30 | ノボザイムス バイオファーマ デーコー アクティーゼルスカブ | 高分子量ヒアルロン酸の噴霧乾燥 |
| JP5714456B2 (ja) * | 2011-09-07 | 2015-05-07 | 株式会社シード | 重合性ヒアルロン酸誘導体、ならびにその重合体を含むヒアルロン酸ヒドロゲルおよびコンタクトレンズ |
| US9492484B2 (en) * | 2012-09-27 | 2016-11-15 | The Regents Of The University Of California | Cardiosphere derived cell population and methods of use |
| CN104224688B (zh) * | 2013-06-09 | 2017-10-10 | 北京化工大学 | 负载纳米药物的丙烯酸酯化透明质酸水凝胶及其制备方法 |
| US10335515B2 (en) * | 2013-09-25 | 2019-07-02 | The University Of Kansas | Hydrogel precursors having nanoparticles |
| EP2899214A1 (en) * | 2014-01-27 | 2015-07-29 | Basf Se | Ethylenically unsaturated polysaccharides, method for their production and their use |
| FR3021541B1 (fr) * | 2014-05-28 | 2017-10-27 | Oreal | Procede cosmetique pour attenuer les rides |
| FR3021537B1 (fr) | 2014-05-28 | 2016-05-27 | Oreal | Procede cosmetique pour attenuer les rides |
| FR3026298B1 (fr) * | 2014-09-30 | 2017-12-01 | Oreal | Procede cosmetique pour attenuer les rides |
| FR3026300B1 (fr) * | 2014-09-30 | 2020-01-10 | L'oreal | Procede cosmetique pour attenuer les rides |
| FR3026299B1 (fr) * | 2014-09-30 | 2016-11-25 | Oreal | Procede cosmetique pour attenuer les rides |
| CN106967202B (zh) * | 2017-03-06 | 2020-05-22 | 深圳大学 | 纳米凝胶酶及其制备和应用 |
| JP2018153296A (ja) * | 2017-03-16 | 2018-10-04 | Jsr株式会社 | 不飽和化合物を含有する組成物 |
| WO2018187184A1 (en) * | 2017-04-04 | 2018-10-11 | The Regents Of The University Of California | Injectable therapeutic angiogenic material for brain repair |
| KR101974745B1 (ko) * | 2017-10-18 | 2019-09-06 | 서울과학기술대학교 산학협력단 | 그라프트 공중합체와 젤라틴 가교물을 포함하는 히알루론산 하이드로젤 및 이의 제조방법 |
| KR101974744B1 (ko) * | 2017-10-12 | 2019-09-06 | 서울과학기술대학교 산학협력단 | 히알루론산 그라프트 공중합체의 가교물을 포함하는 하이드로젤 및 이의 제조방법 |
| KR102103180B1 (ko) * | 2017-12-22 | 2020-04-22 | 케이비바이오메드 주식회사 | 히알루론산유도체, 플루란 및 카르복시메틸 셀룰로오스를 포함하는 유착방지용 조성물 및 이의 제조방법 |
| CN111359011A (zh) * | 2020-03-31 | 2020-07-03 | 东华大学 | 一种提升酰胺化反应用于制备蛋白质生物墨水的方法 |
| CN113943382B (zh) * | 2020-07-16 | 2023-03-10 | 孛朗孚(杭州)生物科技有限公司 | 一种丙烯酸酯类修饰的透明质酸（钠）及其合成方法和应用 |
| US11890642B2 (en) * | 2020-12-30 | 2024-02-06 | Convatec Technologies Inc. | Surface treatment system and method for subcutaneous device |
| CN116874640B (zh) * | 2023-07-24 | 2025-08-08 | 江南大学 | 一种长驻留的用于头发修护的透明质酸钠衍生物及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2121129A1 (en) * | 1991-10-29 | 1993-05-13 | Patrick Soon-Shiong | Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release |
| US6951743B2 (en) * | 1997-10-31 | 2005-10-04 | University Of Oklahoma Board Of Regents | Hyaluronan synthase genes and expression thereof in bacillus hosts |
| US6007833A (en) * | 1998-03-19 | 1999-12-28 | Surmodics, Inc. | Crosslinkable macromers bearing initiator groups |
| US6716445B2 (en) * | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
| ES2298135T3 (es) * | 1999-04-12 | 2008-05-16 | Cornell Research Foundation, Inc. | Sistema formador de hidrogel con componentes hidrofobos e hidrofilos. |
| US6566469B1 (en) * | 1999-06-22 | 2003-05-20 | Trustees Of Tufts College | Enzyme-mediated polymerization methods and products |
| US20020192182A1 (en) * | 2001-03-12 | 2002-12-19 | Stephen Massia | Polysaccharide-based polymerizable hydrogels |
| US6673919B2 (en) * | 2001-03-30 | 2004-01-06 | Chisso Cororation | Chemically modified hyaluronic acid or salts thereof, and a process for producing thereof |
| KR100879908B1 (ko) * | 2001-12-21 | 2009-01-21 | 노보자임스 바이오폴리머 에이/에스 | 재조합체 숙주 세포에서 히알루로난의 제조 방법 |
| US7311879B2 (en) * | 2003-08-14 | 2007-12-25 | Hodson Steve J | Syringe pump |
| US8293890B2 (en) * | 2004-04-30 | 2012-10-23 | Advanced Cardiovascular Systems, Inc. | Hyaluronic acid based copolymers |
-
2007
- 2007-03-09 PL PL07758243T patent/PL1999160T3/pl unknown
- 2007-03-09 JP JP2009500563A patent/JP5123285B2/ja not_active Expired - Fee Related
- 2007-03-09 WO PCT/US2007/063671 patent/WO2007106738A2/en not_active Ceased
- 2007-03-09 DK DK07758243.5T patent/DK1999160T3/da active
- 2007-03-09 AT AT07758243T patent/ATE453670T1/de active
- 2007-03-09 CA CA002647481A patent/CA2647481A1/en not_active Abandoned
- 2007-03-09 DE DE602007004086T patent/DE602007004086D1/de active Active
- 2007-03-09 US US12/280,187 patent/US20090118423A1/en not_active Abandoned
- 2007-03-09 CN CN2007800092919A patent/CN101405303B/zh not_active Expired - Fee Related
- 2007-03-09 EP EP07758243A patent/EP1999160B1/en not_active Not-in-force
- 2007-03-09 AU AU2007226690A patent/AU2007226690B2/en not_active Ceased
- 2007-03-09 ES ES07758243T patent/ES2339181T3/es active Active
- 2007-03-09 BR BRPI0708776-4A patent/BRPI0708776A2/pt not_active IP Right Cessation
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