JP2009522435A - ペンダントおよび末端キャップ性のカチオン性かつ重合性の基を含むシロキサンプレポリマー - Google Patents
ペンダントおよび末端キャップ性のカチオン性かつ重合性の基を含むシロキサンプレポリマー Download PDFInfo
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- 125000004593 naphthyridinyl group Chemical group N1=C(C=CC2=CC=CN=C12)* 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 125000002868 norbornyl group Chemical group C12(CCC(CC1)C2)* 0.000 description 1
- 125000005060 octahydroindolyl group Chemical group N1(CCC2CCCCC12)* 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 125000005375 organosiloxane group Chemical group 0.000 description 1
- 125000001715 oxadiazolyl group Chemical group 0.000 description 1
- 125000000160 oxazolidinyl group Chemical group 0.000 description 1
- 125000005968 oxazolinyl group Chemical group 0.000 description 1
- 125000002971 oxazolyl group Chemical group 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 125000004043 oxo group Chemical group O=* 0.000 description 1
- 125000005476 oxopyrrolidinyl group Chemical group 0.000 description 1
- 125000006340 pentafluoro ethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 125000001791 phenazinyl group Chemical group C1(=CC=CC2=NC3=CC=CC=C3N=C12)* 0.000 description 1
- 125000001484 phenothiazinyl group Chemical group C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 description 1
- 125000001644 phenoxazinyl group Chemical group C1(=CC=CC=2OC3=CC=CC=C3NC12)* 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 125000004592 phthalazinyl group Chemical group C1(=NN=CC2=CC=CC=C12)* 0.000 description 1
- 125000004193 piperazinyl group Chemical group 0.000 description 1
- 125000003386 piperidinyl group Chemical group 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 description 1
- 125000003367 polycyclic group Chemical group 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 229920005597 polymer membrane Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 125000001042 pteridinyl group Chemical group N1=C(N=CC2=NC=CN=C12)* 0.000 description 1
- 125000000561 purinyl group Chemical group N1=C(N=C2N=CNC2=C1)* 0.000 description 1
- 125000003373 pyrazinyl group Chemical group 0.000 description 1
- 125000002098 pyridazinyl group Chemical group 0.000 description 1
- 125000004076 pyridyl group Chemical group 0.000 description 1
- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 125000002294 quinazolinyl group Chemical group N1=C(N=CC2=CC=CC=C12)* 0.000 description 1
- 125000002943 quinolinyl group Chemical group N1=C(C=CC2=CC=CC=C12)* 0.000 description 1
- 125000005493 quinolyl group Chemical group 0.000 description 1
- 125000001567 quinoxalinyl group Chemical group N1=C(C=NC2=CC=CC=C12)* 0.000 description 1
- 125000004621 quinuclidinyl group Chemical group N12C(CC(CC1)CC2)* 0.000 description 1
- 238000010526 radical polymerization reaction Methods 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000012925 reference material Substances 0.000 description 1
- 238000000611 regression analysis Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 239000002210 silicon-based material Substances 0.000 description 1
- 125000005401 siloxanyl group Chemical group 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000004528 spin coating Methods 0.000 description 1
- 125000003003 spiro group Chemical group 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 125000000547 substituted alkyl group Chemical group 0.000 description 1
- 125000005346 substituted cycloalkyl group Chemical group 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Chemical group 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 description 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
- 125000001113 thiadiazolyl group Chemical group 0.000 description 1
- 125000006090 thiamorpholinyl sulfone group Chemical group 0.000 description 1
- 125000006089 thiamorpholinyl sulfoxide group Chemical group 0.000 description 1
- 125000001984 thiazolidinyl group Chemical group 0.000 description 1
- 125000002769 thiazolinyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 125000004568 thiomorpholinyl group Chemical group 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 125000001425 triazolyl group Chemical group 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/38—Polysiloxanes modified by chemical after-treatment
- C08G77/382—Polysiloxanes modified by chemical after-treatment containing atoms other than carbon, hydrogen, oxygen or silicon
- C08G77/388—Polysiloxanes modified by chemical after-treatment containing atoms other than carbon, hydrogen, oxygen or silicon containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/42—Block-or graft-polymers containing polysiloxane sequences
- C08G77/452—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Eyeglasses (AREA)
- Materials For Medical Uses (AREA)
- Silicon Polymers (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75698206P | 2006-01-06 | 2006-01-06 | |
| US11/565,151 US7528208B2 (en) | 2006-01-06 | 2006-11-30 | Siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups |
| PCT/US2007/060069 WO2007082119A2 (en) | 2006-01-06 | 2007-01-04 | Siloxane prepolymer containing pendant and end-capping cationic and polymerizable groups |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009522435A true JP2009522435A (ja) | 2009-06-11 |
| JP2009522435A5 JP2009522435A5 (enExample) | 2010-02-25 |
Family
ID=38141106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549630A Pending JP2009522435A (ja) | 2006-01-06 | 2007-01-04 | ペンダントおよび末端キャップ性のカチオン性かつ重合性の基を含むシロキサンプレポリマー |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7528208B2 (enExample) |
| EP (1) | EP1969035A2 (enExample) |
| JP (1) | JP2009522435A (enExample) |
| WO (1) | WO2007082119A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009522434A (ja) * | 2006-01-06 | 2009-06-11 | ボーシュ アンド ローム インコーポレイティド | ペンダント状陽イオンおよび重合可能基を含有するシロキサンプレポリマー |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7759408B2 (en) * | 2005-12-21 | 2010-07-20 | Bausch & Lomb Incorporated | Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups |
| US20070161769A1 (en) * | 2006-01-06 | 2007-07-12 | Schorzman Derek A | Polymerizable silicon-containing monomer bearing pendant cationic hydrophilic groups |
| US7825273B2 (en) * | 2006-01-06 | 2010-11-02 | Bausch & Lomb Incorporated | Process for making cationic hydrophilic siloxanyl monomers |
| US7960447B2 (en) * | 2006-04-13 | 2011-06-14 | Bausch & Lomb Incorporated | Cationic end-capped siloxane prepolymer for reduced cross-link density |
| US8105623B2 (en) * | 2006-06-30 | 2012-01-31 | Bausch & Lomb Incorporated | Fluorinated poly(ether)s end-capped with polymerizable cationic hydrophilic groups |
| US20080076897A1 (en) * | 2006-09-27 | 2008-03-27 | Kunzler Jay F | Pendant end-capped low modulus cationic siloxanyls |
| US7579021B2 (en) * | 2006-09-27 | 2009-08-25 | Bausch & Lomb Incorporated | Drug delivery systems based on degradable cationic siloxanyl macromonomers |
| US7781558B2 (en) * | 2006-09-27 | 2010-08-24 | Bausch & Lomb Incorporated | Hydrophilic siloxanyl monomers with pendant polymerizable groups |
| US7951897B2 (en) * | 2007-01-26 | 2011-05-31 | Bausch & Lomb Incorporated | Synthesis of cationic siloxane prepolymers |
| CA2802486C (en) | 2010-07-30 | 2015-01-06 | Novartis Ag | Amphiphilic polysiloxane prepolymers and uses thereof |
| JP5852659B2 (ja) | 2010-10-06 | 2016-02-03 | ノバルティス アーゲー | 水処理可能なシリコーン含有プレポリマー及びその使用 |
| US8993651B2 (en) | 2010-10-06 | 2015-03-31 | Novartis Ag | Polymerizable chain-extended polysiloxanes with pendant hydrophilic groups |
| EP2625217B1 (en) | 2010-10-06 | 2018-07-04 | Novartis AG | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains |
| JP6236059B2 (ja) | 2012-03-22 | 2017-11-22 | モメンティブ パフォーマンス マテリアルズ インコーポレイテッド | 親水性マクロマーおよびそれを含むヒドロゲル |
| US10118994B2 (en) | 2013-01-31 | 2018-11-06 | Momentive Performance Materials Inc. | Water soluble silicone material |
| US10160854B1 (en) | 2015-08-03 | 2018-12-25 | Gl Chemtec Vision Inc. | Hydrogel materials |
| US20240026049A1 (en) | 2022-07-21 | 2024-01-25 | Envision Biomedical LLC | Dual-phase zwitterionic monomers |
Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5424047A (en) * | 1977-07-25 | 1979-02-23 | Bausch & Lomb | Polysiloxane composition and contact lens |
| JPS5694323A (en) * | 1979-12-10 | 1981-07-30 | Bausch & Lomb | Hydrophilic contact lens produced from polysiloxane combined with polymerizable group at its terminal and having hydrophilic group |
| US4891166A (en) * | 1987-06-06 | 1990-01-02 | Th. Goldschmidt Ag | Diquaternary polysiloxanes, their synthesis and use in cosmetic preparations |
| JPH06279560A (ja) * | 1984-09-24 | 1994-10-04 | Ciba Geigy Ag | 不飽和ポリシロキサン、重合性組成物およびそのコンタクトレンズ |
| JPH08120086A (ja) * | 1994-10-21 | 1996-05-14 | Nippon Paint Co Ltd | 新規なオルガノポリシロキサン化合物およびその製造方法 |
| JPH08120085A (ja) * | 1994-10-21 | 1996-05-14 | Nippon Paint Co Ltd | 反応性乳化剤、水性シリコーン変性樹脂、水性塗料および塗膜 |
| JPH09328606A (ja) * | 1996-06-07 | 1997-12-22 | Nippon Paint Co Ltd | 常温硬化性樹脂組成物およびシリコーン含有重合性界面活性剤 |
| JP2001098190A (ja) * | 1999-09-30 | 2001-04-10 | Mitsubishi Chemicals Corp | 活性エネルギー線硬化性被覆組成物 |
| JP2002533503A (ja) * | 1998-12-21 | 2002-10-08 | ノバルティス アクチエンゲゼルシャフト | 両親媒性ブロック共重合体 |
| JP2003176361A (ja) * | 2001-08-23 | 2003-06-24 | Goldschmidt Ag | Ｕｖ光吸収性第四級ポリシロキサン |
| JP2006213920A (ja) * | 2005-02-02 | 2006-08-17 | Goldschmidt Gmbh | Ｕｖ光吸収性第四級ポリシロキサン |
| JP2009513742A (ja) * | 2003-07-04 | 2009-04-02 | チバ ホールディング インコーポレーテッド | ポリオルガノシロキサン |
| JP2009520219A (ja) * | 2005-12-14 | 2009-05-21 | ボーシュ アンド ローム インコーポレイティド | レンズを包装する方法 |
| JP2009521547A (ja) * | 2005-12-21 | 2009-06-04 | ボーシュ アンド ローム インコーポレイティド | 重合可能陽イオン親水基により末端封止されたケイ素含有モノマー |
| JP2009522434A (ja) * | 2006-01-06 | 2009-06-11 | ボーシュ アンド ローム インコーポレイティド | ペンダント状陽イオンおよび重合可能基を含有するシロキサンプレポリマー |
| JP2009522373A (ja) * | 2006-01-06 | 2009-06-11 | ボーシュ アンド ローム インコーポレイティド | 陽イオン親水性シロキサニルモノマー製造のための方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3808179A (en) | 1972-06-16 | 1974-04-30 | Polycon Laboratories | Oxygen-permeable contact lens composition,methods and article of manufacture |
| US4153641A (en) | 1977-07-25 | 1979-05-08 | Bausch & Lomb Incorporated | Polysiloxane composition and contact lens |
| US4686267A (en) | 1985-10-11 | 1987-08-11 | Polymer Technology Corporation | Fluorine containing polymeric compositions useful in contact lenses |
| US4910277A (en) | 1988-02-09 | 1990-03-20 | Bambury Ronald E | Hydrophilic oxygen permeable polymers |
| US5070215A (en) | 1989-05-02 | 1991-12-03 | Bausch & Lomb Incorporated | Novel vinyl carbonate and vinyl carbamate contact lens material monomers |
| US5034461A (en) | 1989-06-07 | 1991-07-23 | Bausch & Lomb Incorporated | Novel prepolymers useful in biomedical devices |
| US5358995A (en) | 1992-05-15 | 1994-10-25 | Bausch & Lomb Incorporated | Surface wettable silicone hydrogels |
| US5321108A (en) | 1993-02-12 | 1994-06-14 | Bausch & Lomb Incorporated | Fluorosilicone hydrogels |
| US5374662A (en) | 1993-03-15 | 1994-12-20 | Bausch & Lomb Incorporated | Fumarate and fumaramide siloxane hydrogel compositions |
| US5451651A (en) | 1993-12-17 | 1995-09-19 | Bausch & Lomb Incorporated | Urea and urethane monomers for contact lens materials |
-
2006
- 2006-11-30 US US11/565,151 patent/US7528208B2/en not_active Expired - Fee Related
-
2007
- 2007-01-04 WO PCT/US2007/060069 patent/WO2007082119A2/en not_active Ceased
- 2007-01-04 EP EP07717823A patent/EP1969035A2/en not_active Withdrawn
- 2007-01-04 JP JP2008549630A patent/JP2009522435A/ja active Pending
Patent Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5424047A (en) * | 1977-07-25 | 1979-02-23 | Bausch & Lomb | Polysiloxane composition and contact lens |
| JPS5694323A (en) * | 1979-12-10 | 1981-07-30 | Bausch & Lomb | Hydrophilic contact lens produced from polysiloxane combined with polymerizable group at its terminal and having hydrophilic group |
| JPH06279560A (ja) * | 1984-09-24 | 1994-10-04 | Ciba Geigy Ag | 不飽和ポリシロキサン、重合性組成物およびそのコンタクトレンズ |
| US4891166A (en) * | 1987-06-06 | 1990-01-02 | Th. Goldschmidt Ag | Diquaternary polysiloxanes, their synthesis and use in cosmetic preparations |
| JPH08120086A (ja) * | 1994-10-21 | 1996-05-14 | Nippon Paint Co Ltd | 新規なオルガノポリシロキサン化合物およびその製造方法 |
| JPH08120085A (ja) * | 1994-10-21 | 1996-05-14 | Nippon Paint Co Ltd | 反応性乳化剤、水性シリコーン変性樹脂、水性塗料および塗膜 |
| JPH09328606A (ja) * | 1996-06-07 | 1997-12-22 | Nippon Paint Co Ltd | 常温硬化性樹脂組成物およびシリコーン含有重合性界面活性剤 |
| JP2002533503A (ja) * | 1998-12-21 | 2002-10-08 | ノバルティス アクチエンゲゼルシャフト | 両親媒性ブロック共重合体 |
| JP2001098190A (ja) * | 1999-09-30 | 2001-04-10 | Mitsubishi Chemicals Corp | 活性エネルギー線硬化性被覆組成物 |
| JP2003176361A (ja) * | 2001-08-23 | 2003-06-24 | Goldschmidt Ag | Ｕｖ光吸収性第四級ポリシロキサン |
| JP2009513742A (ja) * | 2003-07-04 | 2009-04-02 | チバ ホールディング インコーポレーテッド | ポリオルガノシロキサン |
| JP2006213920A (ja) * | 2005-02-02 | 2006-08-17 | Goldschmidt Gmbh | Ｕｖ光吸収性第四級ポリシロキサン |
| JP2009520219A (ja) * | 2005-12-14 | 2009-05-21 | ボーシュ アンド ローム インコーポレイティド | レンズを包装する方法 |
| JP2009521547A (ja) * | 2005-12-21 | 2009-06-04 | ボーシュ アンド ローム インコーポレイティド | 重合可能陽イオン親水基により末端封止されたケイ素含有モノマー |
| JP2009522434A (ja) * | 2006-01-06 | 2009-06-11 | ボーシュ アンド ローム インコーポレイティド | ペンダント状陽イオンおよび重合可能基を含有するシロキサンプレポリマー |
| JP2009522373A (ja) * | 2006-01-06 | 2009-06-11 | ボーシュ アンド ローム インコーポレイティド | 陽イオン親水性シロキサニルモノマー製造のための方法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009522434A (ja) * | 2006-01-06 | 2009-06-11 | ボーシュ アンド ローム インコーポレイティド | ペンダント状陽イオンおよび重合可能基を含有するシロキサンプレポリマー |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007082119A2 (en) | 2007-07-19 |
| WO2007082119A3 (en) | 2007-08-30 |
| US7528208B2 (en) | 2009-05-05 |
| EP1969035A2 (en) | 2008-09-17 |
| US20070160649A1 (en) | 2007-07-12 |
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