JP2009519294A5 - バンコマイシンを精製する方法 - Google Patents
バンコマイシンを精製する方法 Download PDFInfo
- Publication number
- JP2009519294A5 JP2009519294A5 JP2008544968A JP2008544968A JP2009519294A5 JP 2009519294 A5 JP2009519294 A5 JP 2009519294A5 JP 2008544968 A JP2008544968 A JP 2008544968A JP 2008544968 A JP2008544968 A JP 2008544968A JP 2009519294 A5 JP2009519294 A5 JP 2009519294A5
- Authority
- JP
- Japan
- Prior art keywords
- vancomycin
- purifying
- purifying vancomycin
- ultrafiltration
- dissolving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- MYPYJXKWCTUITO-LYRMYLQWSA-N VANCOMYCIN Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title claims 3
- 229960003165 Vancomycin Drugs 0.000 title claims 3
- 108010059993 Vancomycin Proteins 0.000 title claims 3
- 230000014759 maintenance of location Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000000108 ultra-filtration Methods 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Claims (1)
- バンコマイシンを精製する方法であって、
前記バンコマイシンを水に溶解し、３００００Ｄａ未満の公称保持を有する膜を用いて溶液を限外ろ過することにより実施される方法。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05112283A EP1798237A1 (en) | 2005-12-16 | 2005-12-16 | Process for the purification of macrolide antibiotics |
| EP05112283.6 | 2005-12-16 | ||
| PCT/EP2006/069414 WO2007068644A1 (en) | 2005-12-16 | 2006-12-07 | Process for the purification of macrolide antibiotics |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009519294A JP2009519294A (ja) | 2009-05-14 |
| JP2009519294A5 true JP2009519294A5 (ja) | 2010-01-28 |
| JP5124475B2 JP5124475B2 (ja) | 2013-01-23 |
Family
ID=36177625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008544968A Active JP5124475B2 (ja) | 2005-12-16 | 2006-12-07 | 粉末の形態のバンコマイシンから着色不純物を除去する方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8268963B2 (ja) |
| EP (2) | EP1798237A1 (ja) |
| JP (1) | JP5124475B2 (ja) |
| CN (1) | CN101341167B (ja) |
| AT (1) | ATE457994T1 (ja) |
| AU (1) | AU2006326070B2 (ja) |
| CA (1) | CA2628798C (ja) |
| DE (1) | DE602006012360D1 (ja) |
| DK (1) | DK1960418T3 (ja) |
| ES (1) | ES2340804T3 (ja) |
| NO (1) | NO20082935L (ja) |
| PL (1) | PL1960418T3 (ja) |
| PT (1) | PT1960418E (ja) |
| RU (1) | RU2400489C2 (ja) |
| WO (1) | WO2007068644A1 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101101663B1 (ko) * | 2009-01-13 | 2011-12-30 | (주) 제노텍 | 반코마이신 습체의 정제방법 |
| ITLO20110001A1 (it) | 2011-05-03 | 2012-11-04 | Fisiopharma Srl | Flaconi di vancomicina cloroidrata con stabilità migliorata |
| EP2592090A1 (en) * | 2011-11-11 | 2013-05-15 | LEK Pharmaceuticals d.d. | Process of purification of teicoplanin |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2288473A1 (fr) * | 1974-10-22 | 1976-05-21 | Manche Union Coop Agr Laiti | Procede de traitement du lactoserum de fromagerie, notamment en vue de l'extraction de glycoproteides et d'acide sialique |
| US4667024A (en) | 1983-07-13 | 1987-05-19 | Smithkline Beckman Corporation | Process for the preparation of purified vancomycin class antibiotics |
| JPH0689038B2 (ja) * | 1983-12-12 | 1994-11-09 | イーライ・リリー・アンド・カンパニー | バンコマイシン改良精製法およびその生産物 |
| JPH0260598A (ja) * | 1988-08-22 | 1990-03-01 | Glaxo Group Ltd | 抗生物質の製造 |
| JP2577133B2 (ja) * | 1989-11-27 | 1997-01-29 | スティフティング フォール ド テフニスヘ ウェッテンスハッペン | 船舶のプロペラ |
| US5258495A (en) * | 1990-07-10 | 1993-11-02 | Abbott Laboratories | Process for making vancomycin HC1 |
| SI9500040B (sl) * | 1995-02-07 | 2002-02-28 | Lek, | Kromatografsko čiščenje Vankomicin hidroklorida z uporabo preparativne HPLC |
| SI9500039B (sl) | 1995-02-07 | 2002-02-28 | Lek, | Nov kombiniran postopek čiščenja Vankomicin hidroklorida |
| JPH10225299A (ja) * | 1996-12-11 | 1998-08-25 | Nippon Kayaku Co Ltd | バンコマイシンの製造方法 |
| US6391851B1 (en) * | 1997-03-10 | 2002-05-21 | Fujisawa Pharmaceutical Co., Ltd. | Hydrochlorides of vancomycin antibiotics and process for producing the same |
| JP4142149B2 (ja) | 1997-07-10 | 2008-08-27 | 明治製菓株式会社 | バンコマイシンの凍結乾燥製剤 |
| CN1056377C (zh) * | 1998-01-22 | 2000-09-13 | 清华大学 | 用环烷酸萃取体系提取和纯化抗生素 |
| KR100870660B1 (ko) * | 2001-12-31 | 2008-11-26 | 엘지디스플레이 주식회사 | 패널의 합착력이 향상된 액정표시소자 및 제조방법 |
| KR100476818B1 (ko) * | 2002-07-19 | 2005-03-17 | 종근당바이오 주식회사 | 테이코플라닌 에이 투 정제 방법 |
| CN1301331C (zh) * | 2003-12-26 | 2007-02-21 | 三达膜科技（厦门）有限公司 | 应用膜提取发酵类大环内酯型抗生素的方法 |
| KR100474653B1 (ko) * | 2004-04-16 | 2005-03-14 | 동국제약 주식회사 | 타이코플라닌의 고순도 생산방법 |
| SI21924A (sl) | 2004-12-07 | 2006-06-30 | Lek Farmacevtska Druzba D.D. | Cist vankomicin hidroklorid |
-
2005
- 2005-12-16 EP EP05112283A patent/EP1798237A1/en not_active Withdrawn
-
2006
- 2006-12-07 CA CA2628798A patent/CA2628798C/en not_active Expired - Fee Related
- 2006-12-07 US US12/095,642 patent/US8268963B2/en active Active
- 2006-12-07 PT PT06841295T patent/PT1960418E/pt unknown
- 2006-12-07 PL PL06841295T patent/PL1960418T3/pl unknown
- 2006-12-07 AT AT06841295T patent/ATE457994T1/de active
- 2006-12-07 CN CN200680045911XA patent/CN101341167B/zh not_active Expired - Fee Related
- 2006-12-07 DE DE602006012360T patent/DE602006012360D1/de active Active
- 2006-12-07 AU AU2006326070A patent/AU2006326070B2/en not_active Ceased
- 2006-12-07 DK DK06841295.6T patent/DK1960418T3/da active
- 2006-12-07 RU RU2008128465/04A patent/RU2400489C2/ru not_active IP Right Cessation
- 2006-12-07 ES ES06841295T patent/ES2340804T3/es active Active
- 2006-12-07 WO PCT/EP2006/069414 patent/WO2007068644A1/en active Application Filing
- 2006-12-07 EP EP06841295A patent/EP1960418B1/en active Active
- 2006-12-07 JP JP2008544968A patent/JP5124475B2/ja active Active
-
2008
- 2008-06-30 NO NO20082935A patent/NO20082935L/no not_active Application Discontinuation
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