JP2009510171A5 - - Google Patents
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- JP2009510171A5 JP2009510171A5 JP2008534665A JP2008534665A JP2009510171A5 JP 2009510171 A5 JP2009510171 A5 JP 2009510171A5 JP 2008534665 A JP2008534665 A JP 2008534665A JP 2008534665 A JP2008534665 A JP 2008534665A JP 2009510171 A5 JP2009510171 A5 JP 2009510171A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- leukemia
- composition according
- isoindol
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- GOTYRUGSSMKFNF-UHFFFAOYSA-N lenalidomide Chemical compound C1C=2C(N)=CC=CC=2C(=O)N1C1CCC(=O)NC1=O GOTYRUGSSMKFNF-UHFFFAOYSA-N 0.000 claims 11
- 208000032839 leukemia Diseases 0.000 claims 9
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 7
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 7
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 7
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 4
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 4
- 239000013543 active substance Substances 0.000 claims 4
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 2
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 2
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 2
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 2
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 2
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 229960004641 rituximab Drugs 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108010002386 Interleukin-3 Proteins 0.000 claims 1
- 102100039064 Interleukin-3 Human genes 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 238000011443 conventional therapy Methods 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229940111134 coxibs Drugs 0.000 claims 1
- 239000003255 cyclooxygenase 2 inhibitor Substances 0.000 claims 1
- 229960000390 fludarabine Drugs 0.000 claims 1
- GIUYCYHIANZCFB-FJFJXFQQSA-N fludarabine phosphate Chemical group C1=NC=2C(N)=NC(F)=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O GIUYCYHIANZCFB-FJFJXFQQSA-N 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 230000002584 immunomodulator Effects 0.000 claims 1
- 229960003444 immunosuppressant agent Drugs 0.000 claims 1
- 230000001861 immunosuppressant effect Effects 0.000 claims 1
- 239000003018 immunosuppressive agent Substances 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/244,117 | 2005-10-04 | ||
| US11/244,117 US7393862B2 (en) | 2002-05-17 | 2005-10-04 | Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias |
| PCT/US2006/038844 WO2007041637A2 (en) | 2005-10-04 | 2006-10-03 | Methods using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013005399A Division JP2013091659A (ja) | 2005-10-04 | 2013-01-16 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009510171A JP2009510171A (ja) | 2009-03-12 |
| JP2009510171A5 true JP2009510171A5 (enExample) | 2009-08-27 |
| JP5916977B2 JP5916977B2 (ja) | 2016-05-11 |
Family
ID=37603038
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008534665A Active JP5916977B2 (ja) | 2005-10-04 | 2006-10-03 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
| JP2013005399A Pending JP2013091659A (ja) | 2005-10-04 | 2013-01-16 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
| JP2014188693A Pending JP2015044811A (ja) | 2005-10-04 | 2014-09-17 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
| JP2017136968A Pending JP2017222686A (ja) | 2005-10-04 | 2017-07-13 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013005399A Pending JP2013091659A (ja) | 2005-10-04 | 2013-01-16 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
| JP2014188693A Pending JP2015044811A (ja) | 2005-10-04 | 2014-09-17 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
| JP2017136968A Pending JP2017222686A (ja) | 2005-10-04 | 2017-07-13 | 特定の白血病の治療のために３−（４−アミノ−１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−ピペリジン−２，６−ジオンを使用する方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (7) | US7393862B2 (enExample) |
| EP (2) | EP2526946A1 (enExample) |
| JP (4) | JP5916977B2 (enExample) |
| KR (3) | KR20160105940A (enExample) |
| CN (2) | CN103142594A (enExample) |
| AR (1) | AR057868A1 (enExample) |
| AU (1) | AU2006299431B2 (enExample) |
| BR (1) | BRPI0616670A2 (enExample) |
| CA (2) | CA2570755A1 (enExample) |
| IL (1) | IL190437A (enExample) |
| NO (1) | NO20082068L (enExample) |
| NZ (1) | NZ567049A (enExample) |
| PE (1) | PE20070761A1 (enExample) |
| RU (2) | RU2406501C2 (enExample) |
| TW (1) | TWI415610B (enExample) |
| UA (1) | UA94062C2 (enExample) |
| WO (1) | WO2007041637A2 (enExample) |
| ZA (1) | ZA200803700B (enExample) |
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| USRE48890E1 (en) | 2002-05-17 | 2022-01-11 | Celgene Corporation | Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation |
| US7968569B2 (en) | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
| US8404716B2 (en) | 2002-10-15 | 2013-03-26 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
| US11116782B2 (en) | 2002-10-15 | 2021-09-14 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
| US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
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