JP2009507503A5 - - Google Patents
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- Publication number
- JP2009507503A5 JP2009507503A5 JP2008530428A JP2008530428A JP2009507503A5 JP 2009507503 A5 JP2009507503 A5 JP 2009507503A5 JP 2008530428 A JP2008530428 A JP 2008530428A JP 2008530428 A JP2008530428 A JP 2008530428A JP 2009507503 A5 JP2009507503 A5 JP 2009507503A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- virus
- particle
- recombinant
- plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 claims 61
- 241000700605 Viruses Species 0.000 claims 55
- 241000196324 Embryophyta Species 0.000 claims 32
- 102000037865 fusion proteins Human genes 0.000 claims 31
- 108020001507 fusion proteins Proteins 0.000 claims 31
- 101710132601 Capsid protein Proteins 0.000 claims 27
- 101710094648 Coat protein Proteins 0.000 claims 27
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 27
- 101710125418 Major capsid protein Proteins 0.000 claims 27
- 101710141454 Nucleoprotein Proteins 0.000 claims 27
- 101710083689 Probable capsid protein Proteins 0.000 claims 27
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 26
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 26
- 102000004169 proteins and genes Human genes 0.000 claims 18
- 108090000623 proteins and genes Proteins 0.000 claims 18
- 239000011159 matrix material Substances 0.000 claims 14
- 108090000765 processed proteins & peptides Proteins 0.000 claims 14
- 108060003951 Immunoglobulin Proteins 0.000 claims 12
- 102000018358 immunoglobulin Human genes 0.000 claims 12
- 238000000034 method Methods 0.000 claims 10
- 125000000539 amino acid group Chemical group 0.000 claims 9
- 241001147459 Turnip vein-clearing virus Species 0.000 claims 6
- 108090000565 Capsid Proteins Proteins 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 108010088160 Staphylococcal Protein A Proteins 0.000 claims 2
- 241000723873 Tobacco mosaic virus Species 0.000 claims 2
- 101710120037 Toxin CcdB Proteins 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 241000589158 Agrobacterium Species 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 102000009786 Immunoglobulin Constant Regions Human genes 0.000 claims 1
- 108010009817 Immunoglobulin Constant Regions Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 108700011201 Streptococcus IgG Fc-binding Proteins 0.000 claims 1
- 238000001261 affinity purification Methods 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 229940072221 immunoglobulins Drugs 0.000 claims 1
- 230000002779 inactivation Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 238000009877 rendering Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05020311A EP1764414A1 (en) | 2005-09-17 | 2005-09-17 | Plant viral particles comprising a plurality of fusion proteins consisting of a plant viral coat protein, a peptide linker and a recombinant protein and use of such plant viral particles for protein purification |
| PCT/EP2006/009029 WO2007031339A1 (en) | 2005-09-17 | 2006-09-15 | Plant viral particles comprising a plurality of fusion proteins consisting of a plant viral coat protein, a peptide linker and a recombinant protein and use of such plant viral particles for protein purification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009507503A JP2009507503A (ja) | 2009-02-26 |
| JP2009507503A5 true JP2009507503A5 (enExample) | 2009-09-17 |
Family
ID=35427929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008530428A Pending JP2009507503A (ja) | 2005-09-17 | 2006-09-15 | 植物ウイルスコートタンパク質、ペプチドリンカーおよびリコンビナントタンパク質から成る複数の融合タンパク質を含む植物ウイルス粒子、およびタンパク質精製のためのこのような植物ウイルス粒子の使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090062514A1 (enExample) |
| EP (2) | EP1764414A1 (enExample) |
| JP (1) | JP2009507503A (enExample) |
| KR (1) | KR20080065613A (enExample) |
| CN (1) | CN101268192A (enExample) |
| AU (1) | AU2006291435A1 (enExample) |
| CA (1) | CA2621243A1 (enExample) |
| WO (1) | WO2007031339A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3578646A3 (en) * | 2007-10-31 | 2020-03-18 | Precision Biosciences, Inc. | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences |
| EP2500035A1 (en) | 2011-03-15 | 2012-09-19 | Icon Genetics GmbH | Pharmaceutical formulation containing immunglobulin |
| WO2014074509A1 (en) * | 2012-11-07 | 2014-05-15 | Vacplanta Limted | Production of an immunogen using a plant virus |
| US10117923B2 (en) | 2012-11-07 | 2018-11-06 | Vacplanta Limited | Production of an immunogen using a plant virus |
| US20160000901A1 (en) * | 2013-03-05 | 2016-01-07 | Shifa Biomedical | Compositions and Methods for the Production of Virus-Like Particles |
| EP2777711A1 (en) | 2013-03-11 | 2014-09-17 | Icon Genetics GmbH | Her2/Neu cancer vaccine |
| EP3085774A1 (en) * | 2015-04-20 | 2016-10-26 | QIAGEN GmbH | Method for concentrating, purifying and/or isolating virus particles |
| CN107771218B (zh) * | 2015-06-17 | 2021-12-31 | 先锋国际良种公司 | 植物调节元件及其使用方法 |
| WO2017020570A1 (en) * | 2015-08-06 | 2017-02-09 | Medigen Biotechnology Corp. | Virus-like particle vaccines |
| WO2017051434A1 (en) * | 2015-09-22 | 2017-03-30 | Indian Institute Of Science | Chimeric plant based virus-like-particles, and uses thereof |
| CN106566842B (zh) * | 2016-07-18 | 2019-04-19 | 湖南农业大学 | 一种蛋白或多肽的植物表达载体及其应用 |
| CN108956983B (zh) * | 2018-05-07 | 2021-05-07 | 西北工业大学 | 一种以烟草花叶病毒为模板的微传感器可控阵列化制备方法 |
| US11696948B2 (en) | 2018-06-12 | 2023-07-11 | Kbio Holdings Limited | Vaccines formed by virus and antigen conjugation |
| US11690907B2 (en) | 2018-06-12 | 2023-07-04 | Kbio Holdings Limited | Vaccines formed by virus and antigen conjugation |
| US11529413B2 (en) | 2018-06-12 | 2022-12-20 | Kbio Holdings Limited | Virus and antigen purification and conjugation |
| US11485956B2 (en) | 2018-06-12 | 2022-11-01 | Kbio Holdings Limited | Virus and antigen purification and conjugation |
| CN118684781A (zh) * | 2023-03-21 | 2024-09-24 | 深圳赫兹生命科学技术有限公司 | GnRH-VLP重组去势疫苗及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5466788A (en) | 1985-03-07 | 1995-11-14 | Mycogen Plant Science, Inc. | Subgenomic promoter |
| US5316931A (en) | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US6660500B2 (en) * | 1988-02-26 | 2003-12-09 | Large Scale Biology Corporation | Production of peptides in plants as viral coat protein fusions |
| US5977438A (en) | 1988-02-26 | 1999-11-02 | Biosource Technologies, Inc. | Production of peptides in plants as viral coat protein fusions |
| IT1249603B (it) | 1991-02-21 | 1995-03-09 | Cremona Angelo & Figlio | Stazione di taglio automatizzata per tranciati di legno |
| EP1162267A3 (en) * | 1992-03-31 | 2002-12-18 | Kanebo Limited | Plant virus vector, plasmid, process for expression of foreign gene and process for obtaining foreign gene product |
| JP2880024B2 (ja) * | 1992-03-31 | 1999-04-05 | 鐘紡株式会社 | 植物ウィルスベクター及びプラスミド並びに外来遺伝子を植物中で発現させる方法 |
| JPH06169789A (ja) * | 1992-12-08 | 1994-06-21 | Kanebo Ltd | 外来遺伝子産物の取得方法 |
| US5491076A (en) | 1993-11-01 | 1996-02-13 | The Texas A&M University System | Expression of foreign genes using a replicating polyprotein producing virus vector |
| US5633447A (en) | 1994-08-25 | 1997-05-27 | Mycogen Plant Science, Inc. | Plant tissue comprising a subgenomic promoter |
| DE10049587A1 (de) | 2000-10-06 | 2002-05-02 | Icon Genetics Ag | Vektorsystem für Pflanzen |
| EP1351974B1 (en) * | 2001-01-18 | 2006-07-26 | Icon Genetics, Inc. | Using viruses to detect or purify proteins |
| JP5096743B2 (ja) | 2003-11-10 | 2012-12-12 | アイコン・ジェネティクス・ゲーエムベーハー | Ｒｎａウイルス由来植物発現システム |
| EP1686176A1 (en) | 2005-01-28 | 2006-08-02 | Icon Genetics AG | Production of antibodies in plants with plus-sense single-stranded viral RNA vectors |
-
2005
- 2005-09-17 EP EP05020311A patent/EP1764414A1/en not_active Withdrawn
-
2006
- 2006-09-15 US US12/067,109 patent/US20090062514A1/en not_active Abandoned
- 2006-09-15 CN CNA2006800340346A patent/CN101268192A/zh active Pending
- 2006-09-15 CA CA002621243A patent/CA2621243A1/en not_active Abandoned
- 2006-09-15 JP JP2008530428A patent/JP2009507503A/ja active Pending
- 2006-09-15 KR KR1020087008611A patent/KR20080065613A/ko not_active Ceased
- 2006-09-15 WO PCT/EP2006/009029 patent/WO2007031339A1/en not_active Ceased
- 2006-09-15 AU AU2006291435A patent/AU2006291435A1/en not_active Abandoned
- 2006-09-15 EP EP06792110A patent/EP1926819B1/en active Active
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