JP2009504732A5 - - Google Patents
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- JP2009504732A5 JP2009504732A5 JP2008526905A JP2008526905A JP2009504732A5 JP 2009504732 A5 JP2009504732 A5 JP 2009504732A5 JP 2008526905 A JP2008526905 A JP 2008526905A JP 2008526905 A JP2008526905 A JP 2008526905A JP 2009504732 A5 JP2009504732 A5 JP 2009504732A5
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- JP
- Japan
- Prior art keywords
- tumor
- compound
- formula
- amino
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0501847-8 | 2005-08-19 | ||
| SE0501847 | 2005-08-19 | ||
| SE0501903-9 | 2005-08-30 | ||
| SE0501903A SE528407C2 (sv) | 2005-08-19 | 2005-08-30 | Borföreningar användbara vid BNCT |
| PCT/SE2006/000952 WO2007021234A1 (en) | 2005-08-19 | 2006-08-17 | Boron compounds useful in bnct |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009504732A JP2009504732A (ja) | 2009-02-05 |
| JP2009504732A5 true JP2009504732A5 (https=) | 2009-09-24 |
| JP5053277B2 JP5053277B2 (ja) | 2012-10-17 |
Family
ID=37310298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008526905A Expired - Fee Related JP5053277B2 (ja) | 2005-08-19 | 2006-08-17 | Bnctに有用なホウ素化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8183247B2 (https=) |
| EP (1) | EP1915381B1 (https=) |
| JP (1) | JP5053277B2 (https=) |
| CN (1) | CN101268085B (https=) |
| RU (1) | RU2423368C2 (https=) |
| SE (1) | SE528407C2 (https=) |
| TW (1) | TWI376381B (https=) |
| WO (1) | WO2007021234A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007026701A1 (de) * | 2007-06-01 | 2008-12-04 | Universität Leipzig | Neue chemische Verbindungen, deren Herstellung und deren Verwendung |
| CN101713740B (zh) * | 2009-12-31 | 2012-05-02 | 中国原子能科学研究院 | 分光光度测量生物样品中bnct药物里硼含量的方法 |
| CN104151339B (zh) * | 2013-05-17 | 2017-05-03 | 中国科学院近代物理研究所 | 含硼吖啶衍生物、其制备方法和应用 |
| JP6360113B2 (ja) * | 2016-07-28 | 2018-07-18 | ステラファーマ株式会社 | ホウ素含有化合物 |
| KR101903693B1 (ko) * | 2016-11-28 | 2018-10-04 | 가천대학교 산학협력단 | BSH 합성을 위한 티오피롤리딘을 이용한 Na2[B12H12] 반응 |
| JP7154528B2 (ja) * | 2017-08-25 | 2022-10-18 | 国立大学法人東京工業大学 | ホウ素含有葉酸誘導体 |
| WO2020180390A1 (en) * | 2019-03-04 | 2020-09-10 | TAE Life Sciences | Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof |
| CN112358494B (zh) * | 2020-04-09 | 2021-09-28 | 南京大学 | 一种基于吖啶的碳硼烷衍生物及其在生物显影中的应用 |
| CN112442095B (zh) * | 2020-12-01 | 2022-07-22 | 上海科黛生物科技有限公司 | 一种维生素b12的精制方法及所得产品的应用 |
| CN112979686B (zh) * | 2021-02-08 | 2022-04-08 | 北京大学 | 一种新型硼携带剂、制备方法及其药物制剂 |
| CN116874515B (zh) * | 2023-05-10 | 2025-03-14 | 重庆高硼生物科技有限公司 | 一种氨基酸-bsh靶向杂合体化合物及其制备方法和应用 |
| WO2025165163A1 (ko) * | 2024-01-31 | 2025-08-07 | (주)클리켐바이오 | 붕소중성자포획치료용 알부민 나노플랫폼 및 이를 포함하는 붕소중성자포획치료용 조성물 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272250A (en) | 1992-07-10 | 1993-12-21 | Spielvogel Bernard F | Boronated phosphoramidate compounds |
| US6180766B1 (en) | 1993-12-02 | 2001-01-30 | Raymond F. Schinazi | Nucleosides and oligonucleotides containing boron clusters |
| CN1124821A (zh) * | 1994-02-14 | 1996-06-19 | 肖冠英 | 同步齿带半潜传动全贯流水电机组 |
| US5630786A (en) * | 1994-06-27 | 1997-05-20 | Ionix Corporation | Boron neutron capture enhancement of fast neutron therapy |
| JP2685128B2 (ja) * | 1995-07-21 | 1997-12-03 | 東北大学長 | カルボラン含有ガドリニウム−dtpa錯体、その中間体、およびこれらの製造方法 |
| US6093382A (en) * | 1998-05-16 | 2000-07-25 | Bracco Research Usa Inc. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| DE19905094C1 (de) | 1999-02-01 | 2000-10-12 | Schering Ag | Gadolinium (III)-Komplexe sowie ihre Verwendung für Zweischritt Strahlentherapieformen und diese enthaltende pharmazeutische Mittel |
| JP2001233883A (ja) * | 2000-02-22 | 2001-08-28 | Okayama Pref Gov Shin Gijutsu Shinko Zaidan | カゴ状ホウ素化合物担持ポルフィリン錯体 |
| EP1364954A4 (en) | 2001-02-09 | 2009-10-28 | Hiroyuki Kagechika | Dicarba closo DODECARBORANDERIVATE |
| CA2555597C (en) * | 2004-02-13 | 2016-06-14 | The University Of British Columbia | Radiolabeled compounds and compositions, their precursors and methods for their production |
| JP2005343858A (ja) * | 2004-06-07 | 2005-12-15 | Mebiopharm Co Ltd | ホウ素イオンクラスター脂質及びこれを用いたリポソーム |
| JP2006096870A (ja) * | 2004-09-29 | 2006-04-13 | Stella Chemifa Corp | ホウ素含有化合物 |
-
2005
- 2005-08-30 SE SE0501903A patent/SE528407C2/sv not_active IP Right Cessation
-
2006
- 2006-08-17 EP EP06769619.5A patent/EP1915381B1/en not_active Not-in-force
- 2006-08-17 US US11/990,634 patent/US8183247B2/en active Active
- 2006-08-17 CN CN2006800301784A patent/CN101268085B/zh active Active
- 2006-08-17 JP JP2008526905A patent/JP5053277B2/ja not_active Expired - Fee Related
- 2006-08-17 RU RU2008110472/04A patent/RU2423368C2/ru active
- 2006-08-17 WO PCT/SE2006/000952 patent/WO2007021234A1/en not_active Ceased
- 2006-08-18 TW TW095130337A patent/TWI376381B/zh active
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