JP2009045444A - 貼付剤および貼付製剤 - Google Patents
貼付剤および貼付製剤 Download PDFInfo
- Publication number
- JP2009045444A JP2009045444A JP2008173178A JP2008173178A JP2009045444A JP 2009045444 A JP2009045444 A JP 2009045444A JP 2008173178 A JP2008173178 A JP 2008173178A JP 2008173178 A JP2008173178 A JP 2008173178A JP 2009045444 A JP2009045444 A JP 2009045444A
- Authority
- JP
- Japan
- Prior art keywords
- patch
- adhesive layer
- pressure
- sensitive adhesive
- release liner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 239000000853 adhesive Substances 0.000 title abstract description 11
- 230000001070 adhesive effect Effects 0.000 title abstract description 11
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims abstract description 95
- 239000010410 layer Substances 0.000 claims abstract description 91
- 239000012790 adhesive layer Substances 0.000 claims description 69
- 239000003814 drug Substances 0.000 claims description 11
- 229940079593 drug Drugs 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 7
- 230000000052 comparative effect Effects 0.000 description 14
- 229920002367 Polyisobutene Polymers 0.000 description 11
- -1 polyethylene Polymers 0.000 description 11
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 229920001971 elastomer Polymers 0.000 description 5
- 229920000139 polyethylene terephthalate Polymers 0.000 description 5
- 239000005020 polyethylene terephthalate Substances 0.000 description 5
- 229920005989 resin Polymers 0.000 description 5
- 239000011347 resin Substances 0.000 description 5
- 239000005060 rubber Substances 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- SZNYYWIUQFZLLT-UHFFFAOYSA-N 2-methyl-1-(2-methylpropoxy)propane Chemical compound CC(C)COCC(C)C SZNYYWIUQFZLLT-UHFFFAOYSA-N 0.000 description 2
- 229920002799 BoPET Polymers 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- NIQCNGHVCWTJSM-UHFFFAOYSA-N Dimethyl phthalate Chemical compound COC(=O)C1=CC=CC=C1C(=O)OC NIQCNGHVCWTJSM-UHFFFAOYSA-N 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- WOZVHXUHUFLZGK-UHFFFAOYSA-N dimethyl terephthalate Chemical compound COC(=O)C1=CC=C(C(=O)OC)C=C1 WOZVHXUHUFLZGK-UHFFFAOYSA-N 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920000098 polyolefin Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical compound CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 229920002554 vinyl polymer Polymers 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- KPAPHODVWOVUJL-UHFFFAOYSA-N 1-benzofuran;1h-indene Chemical compound C1=CC=C2CC=CC2=C1.C1=CC=C2OC=CC2=C1 KPAPHODVWOVUJL-UHFFFAOYSA-N 0.000 description 1
- NJPQAIBZIHNJDO-UHFFFAOYSA-N 1-dodecylpyrrolidin-2-one Chemical compound CCCCCCCCCCCCN1CCCC1=O NJPQAIBZIHNJDO-UHFFFAOYSA-N 0.000 description 1
- NZJXADCEESMBPW-UHFFFAOYSA-N 1-methylsulfinyldecane Chemical compound CCCCCCCCCCS(C)=O NZJXADCEESMBPW-UHFFFAOYSA-N 0.000 description 1
- RZRNAYUHWVFMIP-KTKRTIGZSA-N 1-oleoylglycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-KTKRTIGZSA-N 0.000 description 1
- LCZVSXRMYJUNFX-UHFFFAOYSA-N 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol Chemical compound CC(O)COC(C)COC(C)CO LCZVSXRMYJUNFX-UHFFFAOYSA-N 0.000 description 1
- KYBJXQBTQZOHEH-UHFFFAOYSA-N 2-methylpentan-3-yl tetradecanoate Chemical compound C(CCCCCCCCCCCCC)(=O)OC(CC)C(C)C KYBJXQBTQZOHEH-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 1
- 229920000298 Cellophane Polymers 0.000 description 1
- 229920002160 Celluloid Polymers 0.000 description 1
- 239000013032 Hydrocarbon resin Substances 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- ARIWANIATODDMH-UHFFFAOYSA-N Lauric acid monoglyceride Natural products CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 description 1
- 229920003182 Surlyn® Polymers 0.000 description 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical class C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 125000002723 alicyclic group Chemical group 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- VNGOYPQMJFJDLV-UHFFFAOYSA-N dimethyl benzene-1,3-dicarboxylate Chemical compound COC(=O)C1=CC=CC(C(=O)OC)=C1 VNGOYPQMJFJDLV-UHFFFAOYSA-N 0.000 description 1
- FBSAITBEAPNWJG-UHFFFAOYSA-N dimethyl phthalate Natural products CC(=O)OC1=CC=CC=C1OC(C)=O FBSAITBEAPNWJG-UHFFFAOYSA-N 0.000 description 1
- 229960001826 dimethylphthalate Drugs 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- HDERJYVLTPVNRI-UHFFFAOYSA-N ethene;ethenyl acetate Chemical group C=C.CC(=O)OC=C HDERJYVLTPVNRI-UHFFFAOYSA-N 0.000 description 1
- 229920001038 ethylene copolymer Polymers 0.000 description 1
- 229920006244 ethylene-ethyl acrylate Polymers 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000011086 glassine Substances 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 235000013773 glyceryl triacetate Nutrition 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 229920006270 hydrocarbon resin Polymers 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- NYMPGSQKHIOWIO-UHFFFAOYSA-N hydroxy(diphenyl)silicon Chemical class C=1C=CC=CC=1[Si](O)C1=CC=CC=C1 NYMPGSQKHIOWIO-UHFFFAOYSA-N 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 239000005001 laminate film Substances 0.000 description 1
- 229940039717 lanolin Drugs 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 125000005395 methacrylic acid group Chemical group 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- RZRNAYUHWVFMIP-UHFFFAOYSA-N monoelaidin Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-UHFFFAOYSA-N 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical class CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 1
- 229960002446 octanoic acid Drugs 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 229920001484 poly(alkylene) Polymers 0.000 description 1
- 229920002432 poly(vinyl methyl ether) polymer Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920006267 polyester film Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920000346 polystyrene-polyisoprene block-polystyrene Polymers 0.000 description 1
- 150000003097 polyterpenes Chemical class 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- 150000004040 pyrrolidinones Chemical class 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- 229920006298 saran Polymers 0.000 description 1
- 229930195734 saturated hydrocarbon Natural products 0.000 description 1
- 239000013464 silicone adhesive Substances 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 229920006132 styrene block copolymer Polymers 0.000 description 1
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 description 1
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00544—Plasters form or structure
- A61F2013/00646—Medication patches, e.g. transcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00655—Plasters adhesive
- A61F2013/0071—Plasters adhesive containing active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00795—Plasters special helping devices
- A61F2013/00817—Plasters special helping devices handles or handling tabs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/28—Web or sheet containing structurally defined element or component and having an adhesive outermost layer
- Y10T428/2839—Web or sheet containing structurally defined element or component and having an adhesive outermost layer with release or antistick coating
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Adhesive Tapes (AREA)
Abstract
【解決手段】支持体、粘着剤層、および剥離ライナーを備える貼付剤であって、貼付剤のある端部における貼付剤の断面形状は、該貼付剤の端部における粘着剤層の端部の少なくとも一つの部位が、該貼付剤の端部における支持体の端部から剥離ライナーへ垂下した線分よりも、貼付剤の中央部側に位置するものであり、かつ粘着剤層の端部が露出している、貼付剤。
【選択図】 図1
Description
(1)
支持体、粘着剤層、および剥離ライナーを備える貼付剤であって、貼付剤のある端部における貼付剤の断面形状は、該貼付剤の端部における粘着剤層の端部の少なくとも一つの部位が、該貼付剤の端部における支持体の端部から剥離ライナーへ垂下した線分よりも、貼付剤の中央部側に位置するものであり、かつ粘着剤層の端部が露出している、貼付剤;
(2)
粘着剤層の端部の少なくとも一つの該部位が、支持体の該端部または剥離ライナーの該端部よりも、貼付剤の中央部側に位置する、(1)記載の貼付剤;
(3)
貼付剤の断面形状は、粘着剤層の端部の断面形状が貼付剤の中央部側に湾曲した形状である、(1)または(2)記載の貼付剤;
(4)
剥離ライナーの該端部は、支持体の該端部から剥離ライナーまで垂下した線分が剥離ライナーと交わる剥離ライナー上の位置よりも、貼付剤の端部側に位置する、(1)ないし(3)いずれかに記載の貼付剤;
(5)
粘着剤層が有機液状成分を含む、(1)ないし(4)いずれかに記載の貼付剤;
(6)
粘着剤層の厚さが10μm以上である、(1)ないし(5)いずれかに記載の貼付剤;
(7)
(1)ないし(6)いずれかに記載の貼付剤において、粘着剤層がさらに薬物を含む、貼付製剤;
を提供する。
トルエン625.0g、n−ヘキサン875.0g、高分子量ポリイソブチレン(粘度平均分子量4,000,000)104.3g、中分子量ポリイソブチレン(粘度平均分子量55,000)208.7g、脂環族飽和炭化水素樹脂 208.7g、トルエン50.0gを秤量し、均一となるまで攪拌した。その後、油性液状成分(ミリスチン酸イソプロプロピル) 228.2g、トルエン 200.0gを秤量し、ポリイソブチレン溶液に投入し均一となるまで攪拌して塗工液とした。
(2)塗工
塗工液を、厚さ75μmのポリエチレンテレフタレート(以下「PET」)製の剥離ライナーの軽剥離面に、乾燥後の粘着剤層厚さが160μmとなるように塗布した。乾燥後、粘着剤層を、PET製フィルムとPET製不織布との積層体(厚さ40μm)である支持体のPET不織布面と貼り合わせて貼付剤の原反を作製した。
(3)貼付剤の調製
(実施例1)
貼付剤の原反を、カミソリ刃で30mm×20mmの略矩形にカットし、端部の粘着剤層をピンセットで掻き出して、図1に示す本発明の貼付剤を製造した。
(実施例2〜3)
貼付剤の原反に、カミソリ刃を、カミソリ刃と貼付剤の原反とがなす角度の小さいほうの角度が鋭角となるようにあてて貼付剤の原反を30mm×20mmの略矩形にカットして、図2に示す実施例2の本発明の貼付剤、および図3に示す実施例3の本発明の貼付剤を製造した。
(比較例1)
貼付剤の原反に、カミソリ刃を、カミソリ刃と貼付剤の原反とがなす角度が略直角となるようにあてて貼付剤の原反を30mm×20mmの略矩形にカットして、図6に示す比較例1の貼付剤を製造した。
(比較例2)
貼付剤の原反に、カミソリ刃を、カミソリ刃と貼付剤の原反とがなす角度が略直角となるようにあてて、貼付剤の端部近傍を指で押圧しつつ、貼付剤の原反を30mm×20mmの略矩形にカットして、図7に示す比較例2の貼付剤を製造した。
(4)評価
(断面形状)
実施例および比較例の貼付剤の断面形状を、デジタルマイクロスコープ(KEYENCE、VHX−500)にて撮像した(500倍)。実施例1の結果を図8Aに、実施例2の結果を図8Bに、実施例3の結果を図8Cに示した。比較例1の結果を図8Dに、比較例2の結果を図8E示した。また、撮影された画像に基づき、支持体の端部と、粘着剤層の端部が支持体に接する部位との間の距離(距離6)、剥離ライナーの端部と、粘着剤層の端部が剥離ライナーに接する部位との間の距離(距離7)、支持体の粘着剤層側の表面を含む平面と、粘着剤層の端面の接平面とがなす角度(角度8)、および剥離ライナーの粘着剤層側の表面を含む平面と、粘着剤層の端面の接平面とがなす角度(角度9)等を測定し、結果を表1に示した。
(端部のべたつき)
実施例および比較例の貼付剤に、評価者が手で触れて次の基準で評価した。
〇:べたつかない
△:若干べたつくが許容範囲内である
×:べたつく
(ライナーの剥離性)
実施例および比較例の貼付剤の剥離ライナーを、評価者が手で剥離して、次の基準で評価した。
〇:容易に剥離できる
△:剥離できる
×:剥離が困難である
(粘着剤層のはみ出し)
実施例および比較例の貼付剤に、別のPETフィルム(厚さ25μm)を重ねて、荷重(約290g重)を12時間かけ、貼付剤端部の粘着剤層はみ出しを次の基準で評価した。
○:はみ出しは見られない
△:端部の一部の領域ではみ出しが見られるが許容範囲内である
×:端部のほぼすべての領域ではみ出しが見られる
結果を表2に示した。
実施例3では、端部のべたつきおよび粘着剤層のはみ出しが若干みられたほかは、実施例1〜3では、いずれも端部のべたつきおよび粘着剤層のはみ出しはない、または許容範囲内であり、ライナーを容易に剥離することができた。
(i)粘着剤層の端部の少なくとも一つ部位が、貼付剤の端部における支持体の端部から剥離ライナーへ垂下した線分よりも貼付剤の中央部側に位置する形状によって、端部のべたつきが抑制され、剥離ライナーの剥離性が良好となり、粘着剤層のはみ出しが抑制される。
(ii)支持体または剥離ライナーとが接する、粘着剤層の端部の部位が、支持体または剥離ライナーの端部よりも貼付剤の中央部側に位置する形状が、端部のべたつきおよび粘着剤層のはみ出しの点で好ましい。
(iii)粘着剤層の端部の断面形状が貼付剤の中央部側に湾曲した形状が、端部のべたつきおよび粘着剤層のはみ出しの点で好ましい。
1 粘着剤層
2 支持体
3 剥離ライナー
4 部位
5 線分
6 距離
7 距離
8 角度
9 角度
20 被包材
22 吸収層
24 フランジ層
26 支持体
32 剥離ライナー
34 第二主表面
36 端部
Claims (7)
- 支持体、粘着剤層、および剥離ライナーを備える貼付剤であって、貼付剤のある端部における貼付剤の断面形状は、該貼付剤の端部における粘着剤層の端部の少なくとも一つの部位が、該貼付剤の端部における支持体の端部から剥離ライナーへ垂下した線分よりも、貼付剤の中央部側に位置するものであり、かつ粘着剤層の端部が露出している、貼付剤。
- 粘着剤層の端部の少なくとも一つの該部位が、支持体の該端部または剥離ライナーの該端部よりも、貼付剤の中央部側に位置する、請求項1記載の貼付剤。
- 貼付剤の断面形状は、粘着剤層の端部の断面形状が貼付剤の中央部側に湾曲した形状である、請求項1記載の貼付剤。
- 剥離ライナーの該端部は、支持体の該端部から剥離ライナーまで垂下した線分が剥離ライナーと交わる剥離ライナー上の位置よりも、貼付剤の端部側に位置する、請求項1記載の貼付剤。
- 粘着剤層が有機液状成分を含む、請求項1記載の貼付剤。
- 粘着剤層の厚さが10μm以上である、請求項1記載の貼付剤。
- 請求項1記載の貼付剤において、粘着剤層がさらに薬物を含む、貼付製剤。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008173178A JP5097034B2 (ja) | 2007-07-20 | 2008-07-02 | 貼付剤および貼付製剤 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007189250 | 2007-07-20 | ||
JP2007189250 | 2007-07-20 | ||
JP2008173178A JP5097034B2 (ja) | 2007-07-20 | 2008-07-02 | 貼付剤および貼付製剤 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012206990A Division JP5502169B2 (ja) | 2007-07-20 | 2012-09-20 | 貼付剤および貼付製剤の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2009045444A true JP2009045444A (ja) | 2009-03-05 |
JP5097034B2 JP5097034B2 (ja) | 2012-12-12 |
Family
ID=39744992
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008173178A Active JP5097034B2 (ja) | 2007-07-20 | 2008-07-02 | 貼付剤および貼付製剤 |
JP2012206990A Active JP5502169B2 (ja) | 2007-07-20 | 2012-09-20 | 貼付剤および貼付製剤の製造方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012206990A Active JP5502169B2 (ja) | 2007-07-20 | 2012-09-20 | 貼付剤および貼付製剤の製造方法 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20090022987A1 (ja) |
EP (1) | EP2025310B1 (ja) |
JP (2) | JP5097034B2 (ja) |
KR (1) | KR101453564B1 (ja) |
CN (1) | CN101347417B (ja) |
AT (1) | ATE532488T1 (ja) |
CA (1) | CA2637874C (ja) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2292197A1 (en) | 2009-09-08 | 2011-03-09 | Nitto Denko Corporation | Water resistant patch and a method for its production |
JP2011164255A (ja) * | 2010-02-08 | 2011-08-25 | Shin-Etsu Chemical Co Ltd | リソグラフィー用ペリクル |
JP2011177453A (ja) * | 2010-03-03 | 2011-09-15 | Nitto Denko Corp | 貼付剤および貼付製剤 |
JP2013027716A (ja) * | 2007-07-20 | 2013-02-07 | Nitto Denko Corp | 貼付剤および貼付製剤の製造方法 |
JP2013039928A (ja) * | 2011-08-11 | 2013-02-28 | Hitachi Chemical Co Ltd | 粘着フィルム用梱包箱、粘着フィルムの梱包方法、粘着フィルム梱包セット、及び粘着フィルム梱包セットの製造方法 |
JP2020158481A (ja) * | 2019-03-26 | 2020-10-01 | ダイヤ製薬株式会社 | 貼付剤収納包装品の製造方法、及び、貼付剤収納包装品 |
JP2020157033A (ja) * | 2019-03-26 | 2020-10-01 | ダイヤ製薬株式会社 | 貼付剤収納包装品の製造方法、及び、貼付剤収納包装品 |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5015872B2 (ja) * | 2008-07-16 | 2012-08-29 | 日東電工株式会社 | 貼付剤の製造方法 |
JP5776079B2 (ja) * | 2010-02-26 | 2015-09-09 | 日東電工株式会社 | ビソプロロール含有貼付製剤 |
US20140142490A1 (en) * | 2011-07-08 | 2014-05-22 | Mölnlycke Health Care Ab | Self-adhesive wound care product |
CN102973359B (zh) * | 2011-09-02 | 2015-12-16 | 日东电工株式会社 | 胶粘贴片和胶粘制剂 |
KR101387313B1 (ko) * | 2012-02-21 | 2014-04-18 | 삼성전기주식회사 | 플라잉테일 형태의 경연성 인쇄회로기판 제조 방법 및 이에 따라 제조된 플라잉테일 형태의 경연성 인쇄회로기판 |
US11311423B2 (en) * | 2012-12-19 | 2022-04-26 | Nichiban Co., Ltd. | Facial patch |
KR102203908B1 (ko) * | 2014-06-17 | 2021-01-14 | 엘지디스플레이 주식회사 | 접착 필름, 이를 이용한 유기 발광 표시 장치 및 유기 발광 표시 장치 제조 방법 |
JP6152409B1 (ja) * | 2015-12-21 | 2017-06-21 | レノボ・シンガポール・プライベート・リミテッド | 粘着部材および電子機器 |
CN112206222A (zh) * | 2018-11-09 | 2021-01-12 | 北京德默高科医药技术有限公司 | 含有布洛芬结构类似物的多层经皮给药系统 |
EP3744491A1 (en) * | 2019-05-27 | 2020-12-02 | LTS Lohmann Therapie-Systeme AG | Tool set for manufacturing adhesive patches, method of manufacturing an adhesive patch and adhesive layering |
CN114191008A (zh) * | 2022-01-07 | 2022-03-18 | 华中科技大学同济医学院附属协和医院 | 一种粘贴式肝胃固定装置及其使用方法 |
CN114613270B (zh) * | 2022-03-17 | 2024-03-26 | 武汉华星光电半导体显示技术有限公司 | 显示模组及保护支架 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0663071A (ja) * | 1992-06-16 | 1994-03-08 | R Janssen Oru | 傷用被包材を製造する方法 |
JPH111432A (ja) * | 1997-06-09 | 1999-01-06 | Sekisui Chem Co Ltd | 貼付剤 |
JP2000175960A (ja) * | 1998-12-18 | 2000-06-27 | Saitama Daiichi Seiyaku Kk | 貼付剤 |
JP2006075588A (ja) * | 2004-08-12 | 2006-03-23 | Nitto Denko Corp | 貼付材及び貼付製剤 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0539690Y2 (ja) * | 1988-01-18 | 1993-10-08 | ||
GB8820563D0 (en) | 1988-08-31 | 1988-09-28 | Britcair Ltd | Adhesive dressings |
US4915102A (en) | 1988-09-01 | 1990-04-10 | Bertek, Inc. | Hinged dermal applicator |
CA2078961A1 (en) | 1992-04-21 | 1993-10-22 | John Wick | Two-hand pouch patch application |
GB9425783D0 (en) * | 1994-12-21 | 1995-02-22 | Ethical Pharma Ltd | Packaging of patches |
EP0746311B1 (en) * | 1994-12-24 | 2001-07-11 | Pacific Corporation | Medicinal patches for percutaneous administration |
JPH09110679A (ja) * | 1995-10-13 | 1997-04-28 | Nitto Denko Corp | ハップ剤 |
US5733251A (en) | 1996-08-20 | 1998-03-31 | Medical Device Designs, Inc. | Pop top dressing applicator |
DE19918106A1 (de) * | 1999-04-22 | 2000-10-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern |
DE29911111U1 (de) | 1999-06-25 | 1999-09-23 | Novosis Pharma Ag | Pflaster mit vermindertem kalten Fluß |
JP4208187B2 (ja) * | 2002-10-28 | 2009-01-14 | 日東電工株式会社 | 粘着型光学フィルム、粘着型光学フィルムの製造方法および画像表示装置 |
JP5097034B2 (ja) * | 2007-07-20 | 2012-12-12 | 日東電工株式会社 | 貼付剤および貼付製剤 |
-
2008
- 2008-07-02 JP JP2008173178A patent/JP5097034B2/ja active Active
- 2008-07-16 CA CA2637874A patent/CA2637874C/en active Active
- 2008-07-17 US US12/174,869 patent/US20090022987A1/en not_active Abandoned
- 2008-07-17 EP EP08012942A patent/EP2025310B1/en active Active
- 2008-07-17 AT AT08012942T patent/ATE532488T1/de active
- 2008-07-18 KR KR1020080070032A patent/KR101453564B1/ko active IP Right Grant
- 2008-07-21 CN CN2008101281609A patent/CN101347417B/zh active Active
-
2012
- 2012-09-20 JP JP2012206990A patent/JP5502169B2/ja active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0663071A (ja) * | 1992-06-16 | 1994-03-08 | R Janssen Oru | 傷用被包材を製造する方法 |
JPH111432A (ja) * | 1997-06-09 | 1999-01-06 | Sekisui Chem Co Ltd | 貼付剤 |
JP2000175960A (ja) * | 1998-12-18 | 2000-06-27 | Saitama Daiichi Seiyaku Kk | 貼付剤 |
JP2006075588A (ja) * | 2004-08-12 | 2006-03-23 | Nitto Denko Corp | 貼付材及び貼付製剤 |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013027716A (ja) * | 2007-07-20 | 2013-02-07 | Nitto Denko Corp | 貼付剤および貼付製剤の製造方法 |
EP2292197A1 (en) | 2009-09-08 | 2011-03-09 | Nitto Denko Corporation | Water resistant patch and a method for its production |
JP2011057595A (ja) * | 2009-09-08 | 2011-03-24 | Nitto Denko Corp | 耐水性貼付製剤 |
US8974816B2 (en) | 2009-09-08 | 2015-03-10 | Nitto Denko Corporation | Water resistant patch preparation |
JP2011164255A (ja) * | 2010-02-08 | 2011-08-25 | Shin-Etsu Chemical Co Ltd | リソグラフィー用ペリクル |
JP2011177453A (ja) * | 2010-03-03 | 2011-09-15 | Nitto Denko Corp | 貼付剤および貼付製剤 |
JP2013039928A (ja) * | 2011-08-11 | 2013-02-28 | Hitachi Chemical Co Ltd | 粘着フィルム用梱包箱、粘着フィルムの梱包方法、粘着フィルム梱包セット、及び粘着フィルム梱包セットの製造方法 |
JP2020158481A (ja) * | 2019-03-26 | 2020-10-01 | ダイヤ製薬株式会社 | 貼付剤収納包装品の製造方法、及び、貼付剤収納包装品 |
JP2020157033A (ja) * | 2019-03-26 | 2020-10-01 | ダイヤ製薬株式会社 | 貼付剤収納包装品の製造方法、及び、貼付剤収納包装品 |
JP7220850B2 (ja) | 2019-03-26 | 2023-02-13 | ダイヤ製薬株式会社 | 貼付剤収納包装品の製造方法、及び、貼付剤収納包装品 |
Also Published As
Publication number | Publication date |
---|---|
ATE532488T1 (de) | 2011-11-15 |
CA2637874A1 (en) | 2009-01-20 |
JP5502169B2 (ja) | 2014-05-28 |
CN101347417B (zh) | 2013-06-05 |
CA2637874C (en) | 2014-08-19 |
EP2025310A1 (en) | 2009-02-18 |
KR20090009742A (ko) | 2009-01-23 |
US20090022987A1 (en) | 2009-01-22 |
JP2013027716A (ja) | 2013-02-07 |
KR101453564B1 (ko) | 2014-10-21 |
EP2025310B1 (en) | 2011-11-09 |
CN101347417A (zh) | 2009-01-21 |
JP5097034B2 (ja) | 2012-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5502169B2 (ja) | 貼付剤および貼付製剤の製造方法 | |
JP5005277B2 (ja) | 貼付剤および貼付製剤 | |
JP5732266B2 (ja) | 貼付剤 | |
EP2206759B1 (en) | Adhesive preparation and patch preparation | |
JP5285356B2 (ja) | 貼付剤 | |
TW201021771A (en) | Wound dressing | |
KR101809744B1 (ko) | 방수성 첩부 제제 | |
MX2012009913A (es) | Parche adhesivo cutaneo. | |
EP2198817A1 (en) | Patch package structure | |
JP7257410B2 (ja) | 含水系貼付剤 | |
JP5015872B2 (ja) | 貼付剤の製造方法 | |
JP2014087704A (ja) | 貼付剤及び貼付製剤 | |
JP5662038B2 (ja) | 貼付剤および貼付製剤 | |
JP5688121B2 (ja) | 貼付剤 | |
JP2011125558A (ja) | 貼付剤および貼付製剤 | |
JP2010163398A (ja) | シート状貼付剤 | |
JP7219177B2 (ja) | 非水系貼付剤 | |
JP2011125554A (ja) | 貼付剤および貼付製剤 | |
JPH11180862A (ja) | カバー材付き貼付剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101122 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20120510 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120605 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120703 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120731 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120821 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20120911 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20120921 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5097034 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150928 Year of fee payment: 3 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |