JP2008536515A - ワクチンの調製のためのb型肝炎ウイルス表面抗原の発現 - Google Patents

ワクチンの調製のためのb型肝炎ウイルス表面抗原の発現 Download PDF

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JP2008536515A
JP2008536515A JP2008507760A JP2008507760A JP2008536515A JP 2008536515 A JP2008536515 A JP 2008536515A JP 2008507760 A JP2008507760 A JP 2008507760A JP 2008507760 A JP2008507760 A JP 2008507760A JP 2008536515 A JP2008536515 A JP 2008536515A
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composition
hbsag
hbv
coding sequence
plasmid
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アンジェリカ メディナ−セルビー,
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ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0016Combination vaccines based on diphtheria-tetanus-pertussis
    • A61K39/0017Combination vaccines based on whole cell diphtheria-tetanus-pertussis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/05Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/01Animal expressing industrially exogenous proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008507760A 2005-04-18 2006-04-14 ワクチンの調製のためのb型肝炎ウイルス表面抗原の発現 Pending JP2008536515A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67283805P 2005-04-18 2005-04-18
PCT/US2006/014240 WO2006113528A2 (en) 2005-04-18 2006-04-14 Expressing hepatitis b virus surface antigen for vaccine preparation

Publications (2)

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JP2008536515A true JP2008536515A (ja) 2008-09-11
JP2008536515A5 JP2008536515A5 (https=) 2009-03-05

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US (1) US8119146B2 (https=)
EP (2) EP2329843A3 (https=)
JP (1) JP2008536515A (https=)
CN (1) CN101500601A (https=)
BR (1) BRPI0610297A2 (https=)
CA (1) CA2605179A1 (https=)
RU (1) RU2442825C2 (https=)
SG (1) SG175456A1 (https=)
WO (1) WO2006113528A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014500269A (ja) * 2011-11-11 2014-01-09 ノバルティス アーゲー ヒトワクチンとしての使用に適するジフテリアトキソイドの生成のための動物由来成分を含まない発酵培地
JP2016512204A (ja) * 2013-03-13 2016-04-25 江蘇賽▲ヌオ▼威生物医薬有限公司 B型肝炎ワクチン
JP2019526635A (ja) * 2016-08-26 2019-09-19 セラム インスティテュート オブ インディア プライベート リミティド 多価ワクチン組成物
JP2021185152A (ja) * 2015-06-08 2021-12-09 セルム・インスティテュート・オブ・インディア・プライベート・リミテッドSerum Institute of IndiaPrivate Ltd. 多糖−タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法

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ATE526036T1 (de) * 2005-08-02 2011-10-15 Novartis Vaccines & Diagnostic Reduzierung der interferenz zwischen ölhaltigen adjuvanzien und surfactanthaltigen antigenen
NZ598367A (en) * 2005-09-01 2013-10-25 Novartis Vaccines & Diagnostic Multiple vaccination including serogroup C meningococcus
GB0522765D0 (en) * 2005-11-08 2005-12-14 Chiron Srl Combination vaccine manufacture
CN103333938B (zh) * 2013-07-19 2016-12-28 深圳康泰生物制品股份有限公司 重组酿酒酵母表达的乙肝表面抗原及其生产方法、乙肝疫苗及其生产方法
CN104004671A (zh) * 2014-05-13 2014-08-27 江南大学 一种表达乙肝表面抗原的酿酒酵母工程菌及其构建方法和应用
CN104873969B (zh) * 2015-04-16 2018-06-19 南京赛威信生物医药有限公司 基于HBV PreS-S、C抗原及新型佐剂CpG的治疗性乙型肝炎疫苗
NZ790372A (en) 2020-02-23 2026-01-30 Pfizer Escherichia coli compositions and methods thereof

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014500269A (ja) * 2011-11-11 2014-01-09 ノバルティス アーゲー ヒトワクチンとしての使用に適するジフテリアトキソイドの生成のための動物由来成分を含まない発酵培地
JP2016512204A (ja) * 2013-03-13 2016-04-25 江蘇賽▲ヌオ▼威生物医薬有限公司 B型肝炎ワクチン
US9878035B2 (en) 2013-03-13 2018-01-30 Jiangsu Theravac Bio-Pharmaceutical Co., Ltd. Hepatitis B vaccine
JP2021185152A (ja) * 2015-06-08 2021-12-09 セルム・インスティテュート・オブ・インディア・プライベート・リミテッドSerum Institute of IndiaPrivate Ltd. 多糖−タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法
JP2019526635A (ja) * 2016-08-26 2019-09-19 セラム インスティテュート オブ インディア プライベート リミティド 多価ワクチン組成物
JP2021181445A (ja) * 2016-08-26 2021-11-25 セラム インスティテュート オブ インディア プライベート リミティド 多価ワクチン組成物
JP7384667B2 (ja) 2016-08-26 2023-11-21 セラム インスティテュート オブ インディア プライベート リミティド 多価ワクチン組成物

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EP1871411A4 (en) 2010-07-21
RU2007142383A (ru) 2009-05-27
CA2605179A1 (en) 2006-10-26
BRPI0610297A2 (pt) 2010-06-08
SG175456A1 (en) 2011-11-28
US8119146B2 (en) 2012-02-21
EP2329843A3 (en) 2011-09-14
WO2006113528A3 (en) 2009-04-16
US20090175904A1 (en) 2009-07-09
CN101500601A (zh) 2009-08-05
RU2442825C2 (ru) 2012-02-20
EP2329843A2 (en) 2011-06-08
EP1871411A2 (en) 2008-01-02
WO2006113528A2 (en) 2006-10-26

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