JP2008534552A - 血栓症治療用の新規な医薬組成物 - Google Patents
血栓症治療用の新規な医薬組成物 Download PDFInfo
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- JP2008534552A JP2008534552A JP2008503489A JP2008503489A JP2008534552A JP 2008534552 A JP2008534552 A JP 2008534552A JP 2008503489 A JP2008503489 A JP 2008503489A JP 2008503489 A JP2008503489 A JP 2008503489A JP 2008534552 A JP2008534552 A JP 2008534552A
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- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05006711 | 2005-03-29 | ||
| PCT/EP2006/061046 WO2006103206A2 (en) | 2005-03-29 | 2006-03-27 | Combinations comprising at least one direct thrombin inhibitor for the treatment of thrombosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008534552A true JP2008534552A (ja) | 2008-08-28 |
| JP2008534552A5 JP2008534552A5 (https=) | 2009-05-21 |
Family
ID=36423564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008503489A Pending JP2008534552A (ja) | 2005-03-29 | 2006-03-27 | 血栓症治療用の新規な医薬組成物 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20060222640A1 (https=) |
| EP (1) | EP1885354A2 (https=) |
| JP (1) | JP2008534552A (https=) |
| KR (1) | KR20070116936A (https=) |
| CN (1) | CN101151030A (https=) |
| AR (1) | AR056291A1 (https=) |
| AU (1) | AU2006228600A1 (https=) |
| BR (1) | BRPI0608656A2 (https=) |
| CA (1) | CA2602563A1 (https=) |
| CL (1) | CL2010000395A1 (https=) |
| EA (1) | EA015122B1 (https=) |
| IL (1) | IL186267A0 (https=) |
| MX (1) | MX2007010664A (https=) |
| NO (1) | NO20074149L (https=) |
| NZ (1) | NZ562775A (https=) |
| TW (1) | TW200722089A (https=) |
| UA (1) | UA92603C2 (https=) |
| WO (1) | WO2006103206A2 (https=) |
| ZA (1) | ZA200706698B (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014508138A (ja) * | 2011-01-25 | 2014-04-03 | ユニヴェルシテ カソリック ド ルーヴァン | 細胞移植のための組成物および方法 |
| JP2015508054A (ja) * | 2012-01-25 | 2015-03-16 | ユニヴェルシテ カソリック ド ルーヴァンＵｎｉｖｅｒｓｉｔｅ Ｃａｔｈｏｌｉｑｕｅ Ｄｅ Ｌｏｕｖａｉｎ | 細胞移植のための組成物および方法 |
| JP2019206543A (ja) * | 2014-06-11 | 2019-12-05 | グルバ, ディートリッヒGulba, Dietrich | 殺鼠剤としての抗凝血性化合物の使用 |
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| US8906894B1 (en) | 2000-07-27 | 2014-12-09 | Thomas N. Thomas | Methods for preventing and treating thrombotic disorders |
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| DE10339862A1 (de) * | 2003-08-29 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel |
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| AR062057A1 (es) * | 2006-07-17 | 2008-10-15 | Boehringer Ingelheim Int | Uso de los inhibidores directos de la trombina |
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| AR074108A1 (es) * | 2008-11-11 | 2010-12-22 | Boehringer Ingelheim Int | Metodo para tratar o prevenir la trombosis utilizando etexilato de dabigatran o una sal del mismo con eficacia mejorada sobre la terapia convencional con warfarina |
| RU2011132125A (ru) | 2008-12-30 | 2013-02-10 | Тромбологик Апс | Способы идентификации критических пациентов с повышенным риском развития органной недостаточности и соединения для их лечения |
| CN102250099B (zh) * | 2011-05-16 | 2013-10-16 | 中国药科大学 | 一类非肽类抗凝血酶抑制剂、其制法以及医药用途 |
| US20130345262A1 (en) | 2012-06-25 | 2013-12-26 | Boehringer Ingelheim International Gmbh | Method for prevention of stroke |
| EP2722033A1 (en) * | 2012-10-19 | 2014-04-23 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical Compositions of Dabigatran Free Base |
| EP2722034B1 (en) * | 2012-10-19 | 2020-09-16 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral pharmaceutical formulations comprising dabigatran |
| ES2759228T3 (es) | 2013-07-05 | 2020-05-08 | Univ Catholique Louvain | Medio acondicionado de células madre de hígado de adultos y su uso en el tratamiento de trastornos del hígado |
| CN105250286A (zh) * | 2015-11-13 | 2016-01-20 | 谭惠娟 | 一种抗血栓组合物 |
| CN108236612A (zh) * | 2016-12-27 | 2018-07-03 | 李志忠 | 用于冠脉介入手术中抗凝的组合产品及其用途 |
| US12251377B2 (en) | 2019-03-06 | 2025-03-18 | University Of Rochester | Anticoagulant compositions and uses thereof |
| US11654036B2 (en) | 2020-05-26 | 2023-05-23 | Elixir Medical Corporation | Anticoagulant compounds and methods and devices for their use |
| CN115192691B (zh) * | 2022-08-31 | 2025-03-04 | 晓恩医药包装材料(安庆)有限公司 | 一种阿加曲班注射液及预灌封注射器 |
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- 2006-03-27 CN CNA2006800108359A patent/CN101151030A/zh active Pending
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- 2006-03-27 CA CA002602563A patent/CA2602563A1/en not_active Abandoned
- 2006-03-27 BR BRPI0608656-0A patent/BRPI0608656A2/pt not_active IP Right Cessation
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2007
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014508138A (ja) * | 2011-01-25 | 2014-04-03 | ユニヴェルシテ カソリック ド ルーヴァン | 細胞移植のための組成物および方法 |
| JP2015508054A (ja) * | 2012-01-25 | 2015-03-16 | ユニヴェルシテ カソリック ド ルーヴァンＵｎｉｖｅｒｓｉｔｅ Ｃａｔｈｏｌｉｑｕｅ Ｄｅ Ｌｏｕｖａｉｎ | 細胞移植のための組成物および方法 |
| JP2019206543A (ja) * | 2014-06-11 | 2019-12-05 | グルバ, ディートリッヒGulba, Dietrich | 殺鼠剤としての抗凝血性化合物の使用 |
| US11678659B2 (en) | 2014-06-11 | 2023-06-20 | Dietrich Gulba | Use as rodenticides of compounds that inhibit blood coagulation |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006103206A2 (en) | 2006-10-05 |
| US20100184729A1 (en) | 2010-07-22 |
| IL186267A0 (en) | 2008-01-20 |
| CL2010000395A1 (es) | 2010-08-20 |
| WO2006103206A3 (en) | 2007-01-11 |
| BRPI0608656A2 (pt) | 2010-01-19 |
| US20060222640A1 (en) | 2006-10-05 |
| TW200722089A (en) | 2007-06-16 |
| CN101151030A (zh) | 2008-03-26 |
| NZ562775A (en) | 2011-03-31 |
| EA015122B1 (ru) | 2011-06-30 |
| KR20070116936A (ko) | 2007-12-11 |
| MX2007010664A (es) | 2007-12-12 |
| NO20074149L (no) | 2007-12-11 |
| EA200701841A1 (ru) | 2008-02-28 |
| AR056291A1 (es) | 2007-10-03 |
| EP1885354A2 (en) | 2008-02-13 |
| UA92603C2 (ru) | 2010-11-25 |
| AU2006228600A1 (en) | 2006-10-05 |
| CA2602563A1 (en) | 2006-10-05 |
| ZA200706698B (en) | 2008-12-31 |
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