JP2008531585A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008531585A5 JP2008531585A5 JP2007557169A JP2007557169A JP2008531585A5 JP 2008531585 A5 JP2008531585 A5 JP 2008531585A5 JP 2007557169 A JP2007557169 A JP 2007557169A JP 2007557169 A JP2007557169 A JP 2007557169A JP 2008531585 A5 JP2008531585 A5 JP 2008531585A5
- Authority
- JP
- Japan
- Prior art keywords
- groups
- polar
- group
- npl
- nonpolar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 hydroxy ethoxymethyl Chemical group 0.000 claims 67
- 229910052739 hydrogen Inorganic materials 0.000 claims 52
- 239000001257 hydrogen Substances 0.000 claims 52
- 229910052717 sulfur Inorganic materials 0.000 claims 44
- 150000002431 hydrogen Chemical class 0.000 claims 43
- 229910052760 oxygen Inorganic materials 0.000 claims 40
- 125000000217 alkyl group Chemical group 0.000 claims 39
- 238000000034 method Methods 0.000 claims 38
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 29
- IAYJZWFYUSNIPN-UHFFFAOYSA-N 2-[4,5-dihydroxy-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(OC=2C=CC(=CC=2)[N+]([O-])=O)C(O)C1O IAYJZWFYUSNIPN-UHFFFAOYSA-N 0.000 claims 27
- 125000003118 aryl group Chemical group 0.000 claims 27
- 125000001072 heteroaryl group Chemical group 0.000 claims 27
- 125000005843 halogen group Chemical group 0.000 claims 26
- 125000003545 alkoxy group Chemical group 0.000 claims 25
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 19
- 206010028980 Neoplasm Diseases 0.000 claims 17
- 201000011510 cancer Diseases 0.000 claims 15
- 125000005549 heteroarylene group Chemical group 0.000 claims 11
- 125000000732 arylene group Chemical group 0.000 claims 10
- 125000000753 cycloalkyl group Chemical group 0.000 claims 10
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 9
- 125000002431 aminoalkoxy group Chemical group 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 9
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 8
- 125000004442 acylamino group Chemical group 0.000 claims 8
- 125000003342 alkenyl group Chemical group 0.000 claims 8
- 125000003282 alkyl amino group Chemical group 0.000 claims 8
- 125000004414 alkyl thio group Chemical group 0.000 claims 8
- 125000002947 alkylene group Chemical group 0.000 claims 8
- 125000000304 alkynyl group Chemical group 0.000 claims 8
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims 8
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 claims 8
- 125000004093 cyano group Chemical group *C#N 0.000 claims 8
- 125000004663 dialkyl amino group Chemical group 0.000 claims 8
- 125000000623 heterocyclic group Chemical group 0.000 claims 8
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 claims 8
- 150000007659 semicarbazones Chemical class 0.000 claims 8
- 239000012453 solvate Substances 0.000 claims 8
- 239000003085 diluting agent Substances 0.000 claims 7
- 239000003937 drug carrier Substances 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 claims 6
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 6
- 230000002401 inhibitory effect Effects 0.000 claims 5
- 230000005907 cancer growth Effects 0.000 claims 3
- 125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 claims 3
- 235000019260 propionic acid Nutrition 0.000 claims 3
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims 3
- 229930192474 thiophene Natural products 0.000 claims 3
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims 2
- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 claims 2
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims 1
- 125000006619 (C1-C6) dialkylamino group Chemical group 0.000 claims 1
- 125000002030 1,2-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([*:2])C([H])=C1[H] 0.000 claims 1
- 125000001989 1,3-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([H])C([*:2])=C1[H] 0.000 claims 1
- 125000001140 1,4-phenylene group Chemical group [H]C1=C([H])C([*:2])=C([H])C([H])=C1[*:1] 0.000 claims 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 claims 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 claims 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- UGQZLDXDWSPAOM-UHFFFAOYSA-N pyrrolo[3,4-f]isoindole-1,3,5,7-tetrone Chemical group C1=C2C(=O)NC(=O)C2=CC2=C1C(=O)NC2=O UGQZLDXDWSPAOM-UHFFFAOYSA-N 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
- 0 CCCC=C(N)NCc1cc(C)c(*)c(C#Cc2cccc(C#Cc3c(*)c(I=C)cc(CNC(N)=N)c3)c2)c1 Chemical compound CCCC=C(N)NCc1cc(C)c(*)c(C#Cc2cccc(C#Cc3c(*)c(I=C)cc(CNC(N)=N)c3)c2)c1 0.000 description 1
- JHPFXVWWEKHLNZ-UHFFFAOYSA-N CNC(NCCc1cc(C#Cc2cc(C#Cc3cc(Br)cc(CCNC(N)=N)c3)ccc2)cc(Br)c1)=N Chemical compound CNC(NCCc1cc(C#Cc2cc(C#Cc3cc(Br)cc(CCNC(N)=N)c3)ccc2)cc(Br)c1)=N JHPFXVWWEKHLNZ-UHFFFAOYSA-N 0.000 description 1
- HMXJHVZFZQKEQK-UHFFFAOYSA-N NCCNC(c1cc(Br)cc(C#Cc2cccc(C#Cc3cc(Br)cc(C(NCCN)=O)c3)c2)c1)O Chemical compound NCCNC(c1cc(Br)cc(C#Cc2cccc(C#Cc3cc(Br)cc(C(NCCN)=O)c3)c2)c1)O HMXJHVZFZQKEQK-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65609205P | 2005-02-25 | 2005-02-25 | |
| PCT/US2006/006487 WO2006093813A2 (en) | 2005-02-25 | 2006-02-24 | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008531585A JP2008531585A (ja) | 2008-08-14 |
| JP2008531585A5 true JP2008531585A5 (https=) | 2009-04-09 |
Family
ID=36941658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007557169A Pending JP2008531585A (ja) | 2005-02-25 | 2006-02-24 | 表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060241052A1 (https=) |
| EP (5) | EP2301349A2 (https=) |
| JP (1) | JP2008531585A (https=) |
| KR (1) | KR20080004475A (https=) |
| AU (1) | AU2006218805A1 (https=) |
| CA (1) | CA2599205A1 (https=) |
| TW (2) | TW200722098A (https=) |
| WO (1) | WO2006093813A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2289524A1 (en) * | 2001-03-08 | 2011-03-02 | The Trustees Of The University Of Pennsylvania | Facially amphiphillic polymers as anti-infective agents |
| EP2471526A3 (en) | 2003-03-17 | 2012-12-12 | The Trustees Of The University Of Pennsylvania | Facially amphiphillic polymers and oligomers and uses thereof |
| CN1922133A (zh) | 2004-01-23 | 2007-02-28 | 宾夕法尼亚州大学理事会 | 表面两亲性聚芳基和聚芳基炔基聚合物和低聚物及其用途 |
| AU2005254574B2 (en) | 2004-06-15 | 2012-02-02 | Polymedix, Inc. | Polycationic compounds and uses thereof |
| US20090092574A1 (en) | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| KR100842351B1 (ko) * | 2007-01-04 | 2008-06-30 | 한국생명공학연구원 | 인돌 유도체를 유효성분으로 함유하는 암 예방 및 치료용약학적 조성물 |
| RU2530899C2 (ru) | 2008-07-28 | 2014-10-20 | Селлсьютикс Корпорейшн | Противомалярийные соединения |
| TWI478915B (zh) | 2008-10-27 | 2015-04-01 | Cellceutix Corp | 宿主防禦之合成模擬物及其用途 |
| CA2746421A1 (en) * | 2008-12-10 | 2010-06-17 | Polymedix, Inc. | Antimicrobial molecules for treating multi-drug resistant and extensively drug resistant strains of mycobacterium |
| KR101094299B1 (ko) | 2009-12-17 | 2011-12-19 | 삼성모바일디스플레이주식회사 | 선형 증발원 및 이를 포함하는 증착 장치 |
| EP2709619B1 (en) | 2011-05-16 | 2017-10-11 | Cellceutix Corporation | Compounds for use in treatment of mucositis |
| AU2012352621A1 (en) | 2011-12-13 | 2014-07-24 | Cellceutix Corporation | Cyclic compounds and methods of making and using the same |
| MX2014008763A (es) * | 2012-01-18 | 2015-04-13 | Cellceutix Corp | Compuestos y metodos para tratar infecciones por candidosis y aspergillus. |
| CN109305926B (zh) * | 2018-10-18 | 2021-06-25 | 吉林大学 | 一种可形成分子内氢键的芳酰胺类金属配体及其制备方法与应用 |
| WO2021248008A1 (en) | 2020-06-05 | 2021-12-09 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH479557A (de) * | 1961-09-11 | 1969-10-15 | Wander Ag Dr A | Verfahren zur Herstellung neuer mehrbasischer Verbindungen |
| CH525898A (de) * | 1961-09-11 | 1972-07-31 | Wander Ag Dr A | Verfahren zur Herstellung mehrbasischer Verbindungen |
| GB1033777A (en) * | 1963-06-06 | 1966-06-22 | Sterling Drug Inc | Bis-anilide derivatives |
| US3484407A (en) * | 1967-01-13 | 1969-12-16 | Monsanto Co | Linear condensation polymers containing carbonamide and heterocyclic linkages |
| US4118232A (en) * | 1971-04-07 | 1978-10-03 | Ciba-Geigy Ag | Photographic material containing sulphonic acid group containing disazo dyestuffs |
| US3878705A (en) | 1972-05-01 | 1975-04-22 | Roger L Iffland | Bearing cage and method for producing a bearing cage |
| US3829563A (en) * | 1972-11-30 | 1974-08-13 | Hoffmann La Roche | Emollient cleansing compositions |
| US4038416A (en) * | 1975-09-11 | 1977-07-26 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition and method of the use thereof |
| US4392848A (en) * | 1979-06-25 | 1983-07-12 | The Procter & Gamble Company | Catheterization |
| US4343788A (en) * | 1979-06-29 | 1982-08-10 | The Procter & Gamble Company | Antimicrobial polymer compositions |
| US4252951A (en) * | 1979-10-09 | 1981-02-24 | Eli Lilly And Company | Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid |
| FR2527618A1 (fr) * | 1982-05-25 | 1983-12-02 | Thomson Csf | Polymeres contenant des heterocycles et des noyaux aromatiques et materiaux organiques conducteurs formes a partir de ces polymeres |
| US4515910A (en) * | 1983-01-26 | 1985-05-07 | Rawls Henry R | Interpolymeric resin for treatment of teeth |
| DE3533612A1 (de) * | 1985-09-20 | 1987-04-02 | Johannes Reinmueller | Neuartige verwendung von taurolin |
| JPH0739457B2 (ja) * | 1986-05-14 | 1995-05-01 | タキロン株式会社 | 両親媒性セグメントポリウレタン |
| US4826829A (en) * | 1986-07-23 | 1989-05-02 | Fmc Corporation | 2-Substituted ethynyl thiophene pesticides |
| US4847353A (en) * | 1986-11-20 | 1989-07-11 | Nippon Steel Chemical Co., Ltd. | Resins of low thermal expansivity |
| US5856245A (en) * | 1988-03-14 | 1999-01-05 | Nextec Applications, Inc. | Articles of barrier webs |
| US5874164A (en) * | 1988-03-14 | 1999-02-23 | Nextec Applications, Inc. | Barrier webs having bioactive surfaces |
| US6040251A (en) * | 1988-03-14 | 2000-03-21 | Nextec Applications Inc. | Garments of barrier webs |
| US5912116A (en) * | 1988-03-14 | 1999-06-15 | Nextec Applications, Inc. | Methods of measuring analytes with barrier webs |
| US6083602A (en) * | 1988-03-14 | 2000-07-04 | Nextec Applications, Inc. | Incontinent garments |
| JP2597160B2 (ja) * | 1988-09-02 | 1997-04-02 | 富士写真フイルム株式会社 | 電子写真感光体 |
| US4943624A (en) * | 1988-10-28 | 1990-07-24 | Lehigh University | Supramolecular surfactants: amphiphilic polymers designed to disrupt lipid membranes |
| US5071648A (en) * | 1989-04-06 | 1991-12-10 | Merocel Corporation | Polymeric broad-spectrum antimicrobial materials |
| US5073564A (en) * | 1990-07-06 | 1991-12-17 | Fmc Corporation | Ethynylbenzothiophene pesticides |
| US5219965A (en) * | 1990-11-27 | 1993-06-15 | Bausch & Lomb Incorporated | Surface modification of polymer objects |
| US5648070A (en) * | 1991-12-04 | 1997-07-15 | Cobe Laboratories, Inc. | Biocompatible anion exchange materials |
| US5262476A (en) * | 1992-03-10 | 1993-11-16 | The Dow Chemical Company | Polycarbonate/polyester blends modified with poly(phenylene ether) |
| DE19709075A1 (de) * | 1997-03-06 | 1998-09-10 | Huels Chemische Werke Ag | Verfahren zur Herstellung antimikrobieller Kunststoffe |
| US5847047A (en) * | 1993-06-22 | 1998-12-08 | E. I. Du Pont De Nemours And Company | Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type |
| US5520910A (en) * | 1993-07-14 | 1996-05-28 | Nippon Chemical Industrial | Antimicrobial polymer, contact lens and contact lens-care articles |
| US6034129A (en) * | 1996-06-24 | 2000-03-07 | Geltex Pharmaceuticals, Inc. | Ionic polymers as anti-infective agents |
| FR2753094B1 (fr) * | 1996-09-06 | 1998-10-16 | Oreal | Composition de teinture d'oxydation pour fibres keratiniques comprenant un polymere amphiphile anionique |
| US5962521A (en) * | 1997-04-04 | 1999-10-05 | Guilford Pharmaceuticals Inc. | Hydroxamic acid derivatives |
| US6107397A (en) * | 1997-03-24 | 2000-08-22 | Basf Aktiengesellschaft | Aqueous copolymer dispersions of water-soluble monomers with N-vinyl groups and hydrophobic monomers |
| DE19735715A1 (de) * | 1997-08-18 | 1999-02-25 | Huels Chemische Werke Ag | Amphiphile Polymere auf Basis von Polyestern mit einkondensierten acetalischen Gruppen, die bei Raumtemperatur flüssig sind, sowie ihr Einsatz in Wasch- und Reinigungsmitteln |
| US5994340A (en) * | 1997-08-29 | 1999-11-30 | Synphar Laboratories, Inc. | Azetidinone derivatives as β-lactamase inhibitors |
| CA2234410C (en) * | 1998-05-01 | 2002-07-16 | Jih Ru Hwu | Novel phloroglucide derivatives and their pharmaceutical use |
| US6399629B1 (en) * | 1998-06-01 | 2002-06-04 | Microcide Pharmaceuticals, Inc. | Efflux pump inhibitors |
| US6686345B2 (en) * | 1998-07-16 | 2004-02-03 | Research Development Foundation | DNA-cleaving antitumor agents |
| DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
| ES2223464T3 (es) * | 1999-02-01 | 2005-03-01 | Eisai Co., Ltd. | Compuestos adyuvantes inmunologicos. |
| US6166172A (en) * | 1999-02-10 | 2000-12-26 | Carnegie Mellon University | Method of forming poly-(3-substituted) thiophenes |
| DE19908184A1 (de) * | 1999-02-25 | 2000-08-31 | Basf Ag | Verfahren zur Herstellung wässriger Dispersionen von Copolymerisaten aus hydrophilen und hydrophoben Monomeren sowie daraus erhältliche Copolymerisate und deren Anwendungen |
| US6309633B1 (en) * | 1999-06-19 | 2001-10-30 | Nobex Corporation | Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same |
| EP2289524A1 (en) * | 2001-03-08 | 2011-03-02 | The Trustees Of The University Of Pennsylvania | Facially amphiphillic polymers as anti-infective agents |
| US20030130454A1 (en) * | 2001-11-07 | 2003-07-10 | Mitsubishi Rayon Co., Ltd. | Process for producing amphipathic polymers |
| CA2487454A1 (en) * | 2002-05-28 | 2003-12-04 | The Trustees Of The University Of Pennsylvania | Methods, systems, and computer program products for computational analysis and design of amphiphilic polymers |
| EP1513622A4 (en) * | 2002-06-13 | 2005-09-14 | Univ Pennsylvania | METHODS, SYSTEMS AND COMPUTER PROGRAM PRODUCTS FOR STIMULATING BIOMEMBRANES USING ROUGH GRAIN MODELS |
| CA2494695C (en) * | 2002-08-02 | 2011-04-05 | Ab Science | 2-(3-aminoaryl)amino-4-aryl-thiazoles and their use as c-kit inhibitors |
| US7378479B2 (en) * | 2002-09-13 | 2008-05-27 | Lubrizol Advanced Materials, Inc. | Multi-purpose polymers, methods and compositions |
| EP2471526A3 (en) * | 2003-03-17 | 2012-12-12 | The Trustees Of The University Of Pennsylvania | Facially amphiphillic polymers and oligomers and uses thereof |
| US7332623B2 (en) * | 2003-06-30 | 2008-02-19 | Kaohsiung Medical University | Aryl-substituted acyclic enediyne compounds |
| US20050004211A1 (en) * | 2003-06-30 | 2005-01-06 | Kaohsiung Medical University | Pharmaceutical compositions comprising aryl-substituted acyclic enediyne compounds |
| US7781498B2 (en) * | 2003-07-03 | 2010-08-24 | Mallard Creek Polymers, Inc. | Cationic latex as a carrier for bioactive ingredients and methods for making and using the same |
| ITMI20031790A1 (it) * | 2003-09-19 | 2005-03-20 | Consiglio Nazionale Ricerche | Antagonistici abiotici dell'eparina. |
| US20070173752A1 (en) * | 2003-11-28 | 2007-07-26 | Troels Schonfeldt | Integrated package |
| CN1922133A (zh) * | 2004-01-23 | 2007-02-28 | 宾夕法尼亚州大学理事会 | 表面两亲性聚芳基和聚芳基炔基聚合物和低聚物及其用途 |
| AU2005254574B2 (en) * | 2004-06-15 | 2012-02-02 | Polymedix, Inc. | Polycationic compounds and uses thereof |
| JP5027659B2 (ja) * | 2004-07-23 | 2012-09-19 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 抗菌コポリマーおよびその使用 |
-
2006
- 2006-02-24 US US11/361,050 patent/US20060241052A1/en not_active Abandoned
- 2006-02-24 EP EP10015189A patent/EP2301349A2/en not_active Withdrawn
- 2006-02-24 JP JP2007557169A patent/JP2008531585A/ja active Pending
- 2006-02-24 EP EP10015892A patent/EP2298074A3/en not_active Withdrawn
- 2006-02-24 CA CA002599205A patent/CA2599205A1/en not_active Abandoned
- 2006-02-24 AU AU2006218805A patent/AU2006218805A1/en not_active Abandoned
- 2006-02-24 EP EP11010096A patent/EP2433628A1/en not_active Withdrawn
- 2006-02-24 WO PCT/US2006/006487 patent/WO2006093813A2/en not_active Ceased
- 2006-02-24 EP EP06735949A patent/EP1855704A4/en not_active Withdrawn
- 2006-02-24 KR KR1020077022131A patent/KR20080004475A/ko not_active Ceased
- 2006-02-24 EP EP11010095A patent/EP2433627A1/en not_active Withdrawn
- 2006-02-27 TW TW095106642A patent/TW200722098A/zh unknown
- 2006-02-27 TW TW101108505A patent/TW201231063A/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008531585A5 (https=) | ||
| JP2006521355A5 (https=) | ||
| CA2415486A1 (en) | Pyramidine derivatives | |
| JP2010514798A5 (https=) | ||
| KR102012164B1 (ko) | 점막염치료를 위한 조성물 | |
| RU2003120798A (ru) | Новые производные n-(фенилсульфонил) глицина и их применение в терапии | |
| JP2006509749A5 (https=) | ||
| JP2006151984A5 (https=) | ||
| RU2005135016A (ru) | Производные хинолина в качестве ингибиторов фосфодиэстеразы | |
| RU2006131132A (ru) | 1,3,5,-тризамещенные производные 4,5-дигидро-1н-пиразола, обладающие св1-антагонистической активностью | |
| JP2005533766A5 (https=) | ||
| WO2019152536A1 (en) | Inhibitors of the wnt/beta-catenin pathway | |
| JP2004509845A5 (https=) | ||
| JP2008531585A (ja) | 表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用 | |
| JP2005526138A5 (https=) | ||
| WO2006042195A1 (en) | Alkyl benzamides | |
| CA2567797A1 (en) | Peptidic vasopressin receptor agonists | |
| CA2441309A1 (en) | Biguanide derivatives | |
| JP2021512898A5 (https=) | ||
| JP2008519783A5 (https=) | ||
| CA2438509A1 (en) | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | |
| CA2635093A1 (en) | Derivatives of sulindac, use thereof and preparation thereof | |
| MX2007008082A (es) | Formulaciones farmaceuticas de sales de galio. | |
| RU2006105634A (ru) | Производные-аминоамидов, применимые в качестве противовоспалительных агентов | |
| AU2020397821B2 (en) | PDIA4 inhibitors and use thereof for inhibiting ß-cell pathogenesis and treating diabetes |