CA2599205A1 - Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer - Google Patents

Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer Download PDF

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Publication number
CA2599205A1
CA2599205A1 CA002599205A CA2599205A CA2599205A1 CA 2599205 A1 CA2599205 A1 CA 2599205A1 CA 002599205 A CA002599205 A CA 002599205A CA 2599205 A CA2599205 A CA 2599205A CA 2599205 A1 CA2599205 A1 CA 2599205A1
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CA
Canada
Prior art keywords
group
polar
npl
optionally substituted
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002599205A
Other languages
English (en)
French (fr)
Inventor
Gregory N. Tew
Lachelle S. Arnt
William F. Degrado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
University of Massachusetts Amherst
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2599205A1 publication Critical patent/CA2599205A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
CA002599205A 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer Abandoned CA2599205A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65609205P 2005-02-25 2005-02-25
US60/656,092 2005-02-25
PCT/US2006/006487 WO2006093813A2 (en) 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer

Publications (1)

Publication Number Publication Date
CA2599205A1 true CA2599205A1 (en) 2006-09-08

Family

ID=36941658

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002599205A Abandoned CA2599205A1 (en) 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer

Country Status (8)

Country Link
US (1) US20060241052A1 (https=)
EP (5) EP2433628A1 (https=)
JP (1) JP2008531585A (https=)
KR (1) KR20080004475A (https=)
AU (1) AU2006218805A1 (https=)
CA (1) CA2599205A1 (https=)
TW (2) TW200722098A (https=)
WO (1) WO2006093813A2 (https=)

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WO2004082634A2 (en) 2003-03-17 2004-09-30 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers and uses thereof
JP5260877B2 (ja) 2004-01-23 2013-08-14 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 面に対して両親媒性のポリアリール及びポリアリールアルキニルのポリマー及びオリゴマー並びにそれらの使用
KR101172722B1 (ko) 2004-06-15 2012-08-16 폴리메딕스, 인코포레이티드 다가양이온성 화합물 및 이의 용도
US20090092574A1 (en) * 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
KR100842351B1 (ko) * 2007-01-04 2008-06-30 한국생명공학연구원 인돌 유도체를 유효성분으로 함유하는 암 예방 및 치료용약학적 조성물
RU2530899C2 (ru) 2008-07-28 2014-10-20 Селлсьютикс Корпорейшн Противомалярийные соединения
TWI478915B (zh) 2008-10-27 2015-04-01 Cellceutix Corp 宿主防禦之合成模擬物及其用途
EP2389067A4 (en) * 2008-12-10 2012-06-13 Polymedix Inc ANTIMICROBIAL MOLECULES FOR THE TREATMENT OF MYCOBACTERIUM STRAINS WITH MULTIDRUG RESISTANCE AND LARGE RESISTANCE TO DRUGS
KR101094299B1 (ko) 2009-12-17 2011-12-19 삼성모바일디스플레이주식회사 선형 증발원 및 이를 포함하는 증착 장치
DK2709619T3 (en) 2011-05-16 2018-01-15 Cellceutix Corp RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS
WO2013090185A1 (en) 2011-12-13 2013-06-20 Polymedix, Inc. Cyclic compounds and methods of making and using the same
KR20140129030A (ko) * 2012-01-18 2014-11-06 셀슈틱스 코포레이션 캔디다증 및 아스퍼질러스 감염을 치료하기 위한 화합물 및 방법
CN109305926B (zh) * 2018-10-18 2021-06-25 吉林大学 一种可形成分子内氢键的芳酰胺类金属配体及其制备方法与应用
WO2021248008A1 (en) 2020-06-05 2021-12-09 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections

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Also Published As

Publication number Publication date
WO2006093813A2 (en) 2006-09-08
EP2433627A1 (en) 2012-03-28
TW201231063A (en) 2012-08-01
EP2301349A2 (en) 2011-03-30
JP2008531585A (ja) 2008-08-14
AU2006218805A1 (en) 2006-09-08
US20060241052A1 (en) 2006-10-26
EP1855704A2 (en) 2007-11-21
EP2298074A3 (en) 2011-10-26
EP2298074A2 (en) 2011-03-23
TW200722098A (en) 2007-06-16
EP1855704A4 (en) 2009-12-02
KR20080004475A (ko) 2008-01-09
WO2006093813A3 (en) 2007-11-22
EP2433628A1 (en) 2012-03-28

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FZDE Discontinued

Effective date: 20140116