JP2008531585A - 表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用 - Google Patents

表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用 Download PDF

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JP2008531585A
JP2008531585A JP2007557169A JP2007557169A JP2008531585A JP 2008531585 A JP2008531585 A JP 2008531585A JP 2007557169 A JP2007557169 A JP 2007557169A JP 2007557169 A JP2007557169 A JP 2007557169A JP 2008531585 A JP2008531585 A JP 2008531585A
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JP2008531585A5 (https=
Inventor
デグラド,ウイリアム
テウ,グレゴリー
アーント,ラシエル
Original Assignee
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア
ユニバーシテイ・オブ・マサチユセツツ
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Publication of JP2008531585A publication Critical patent/JP2008531585A/ja
Publication of JP2008531585A5 publication Critical patent/JP2008531585A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
JP2007557169A 2005-02-25 2006-02-24 表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用 Pending JP2008531585A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65609205P 2005-02-25 2005-02-25
PCT/US2006/006487 WO2006093813A2 (en) 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer

Publications (2)

Publication Number Publication Date
JP2008531585A true JP2008531585A (ja) 2008-08-14
JP2008531585A5 JP2008531585A5 (https=) 2009-04-09

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JP2007557169A Pending JP2008531585A (ja) 2005-02-25 2006-02-24 表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用

Country Status (8)

Country Link
US (1) US20060241052A1 (https=)
EP (5) EP2301349A2 (https=)
JP (1) JP2008531585A (https=)
KR (1) KR20080004475A (https=)
AU (1) AU2006218805A1 (https=)
CA (1) CA2599205A1 (https=)
TW (2) TW200722098A (https=)
WO (1) WO2006093813A2 (https=)

Cited By (1)

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JP2011529502A (ja) * 2008-07-28 2011-12-08 ポリメディックス・インコーポレーテッド 抗マラリア化合物

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EP2471526A3 (en) 2003-03-17 2012-12-12 The Trustees Of The University Of Pennsylvania Facially amphiphillic polymers and oligomers and uses thereof
CN1922133A (zh) 2004-01-23 2007-02-28 宾夕法尼亚州大学理事会 表面两亲性聚芳基和聚芳基炔基聚合物和低聚物及其用途
AU2005254574B2 (en) 2004-06-15 2012-02-02 Polymedix, Inc. Polycationic compounds and uses thereof
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
KR100842351B1 (ko) * 2007-01-04 2008-06-30 한국생명공학연구원 인돌 유도체를 유효성분으로 함유하는 암 예방 및 치료용약학적 조성물
TWI478915B (zh) 2008-10-27 2015-04-01 Cellceutix Corp 宿主防禦之合成模擬物及其用途
CA2746421A1 (en) * 2008-12-10 2010-06-17 Polymedix, Inc. Antimicrobial molecules for treating multi-drug resistant and extensively drug resistant strains of mycobacterium
KR101094299B1 (ko) 2009-12-17 2011-12-19 삼성모바일디스플레이주식회사 선형 증발원 및 이를 포함하는 증착 장치
EP2709619B1 (en) 2011-05-16 2017-10-11 Cellceutix Corporation Compounds for use in treatment of mucositis
AU2012352621A1 (en) 2011-12-13 2014-07-24 Cellceutix Corporation Cyclic compounds and methods of making and using the same
MX2014008763A (es) * 2012-01-18 2015-04-13 Cellceutix Corp Compuestos y metodos para tratar infecciones por candidosis y aspergillus.
CN109305926B (zh) * 2018-10-18 2021-06-25 吉林大学 一种可形成分子内氢键的芳酰胺类金属配体及其制备方法与应用
WO2021248008A1 (en) 2020-06-05 2021-12-09 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections

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Cited By (1)

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Also Published As

Publication number Publication date
EP1855704A2 (en) 2007-11-21
EP2301349A2 (en) 2011-03-30
CA2599205A1 (en) 2006-09-08
EP2298074A3 (en) 2011-10-26
EP2298074A2 (en) 2011-03-23
WO2006093813A3 (en) 2007-11-22
EP1855704A4 (en) 2009-12-02
KR20080004475A (ko) 2008-01-09
TW200722098A (en) 2007-06-16
US20060241052A1 (en) 2006-10-26
WO2006093813A2 (en) 2006-09-08
AU2006218805A1 (en) 2006-09-08
EP2433628A1 (en) 2012-03-28
TW201231063A (en) 2012-08-01
EP2433627A1 (en) 2012-03-28

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