JP2008517984A5 - - Google Patents
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- JP2008517984A5 JP2008517984A5 JP2007538500A JP2007538500A JP2008517984A5 JP 2008517984 A5 JP2008517984 A5 JP 2008517984A5 JP 2007538500 A JP2007538500 A JP 2007538500A JP 2007538500 A JP2007538500 A JP 2007538500A JP 2008517984 A5 JP2008517984 A5 JP 2008517984A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- hydrogen
- hydrocarbyl
- hydroxy
- cyano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62182104P | 2004-10-25 | 2004-10-25 | |
| US60/621,821 | 2004-10-25 | ||
| GB0423655A GB0423655D0 (en) | 2004-10-25 | 2004-10-25 | Pharmaceutical compounds |
| GB0423655.0 | 2004-10-25 | ||
| US68411905P | 2005-05-24 | 2005-05-24 | |
| US60/684,119 | 2005-05-24 | ||
| PCT/GB2005/004119 WO2006046024A1 (en) | 2004-10-25 | 2005-10-25 | Ortho- condensed pyridine and pyrimidine derivatives (e. g. purines) as protein kinases inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008517984A JP2008517984A (ja) | 2008-05-29 |
| JP2008517984A5 true JP2008517984A5 (enExample) | 2008-12-18 |
| JP5128284B2 JP5128284B2 (ja) | 2013-01-23 |
Family
ID=35715573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007538500A Expired - Lifetime JP5128284B2 (ja) | 2004-10-25 | 2005-10-25 | プロテインキナーゼ阻害剤としてのオルト縮合ピリジンおよびピリミジン誘導体(例えばプリン類) |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8546407B2 (enExample) |
| EP (2) | EP1812004B1 (enExample) |
| JP (1) | JP5128284B2 (enExample) |
| AR (1) | AR051342A1 (enExample) |
| AT (1) | ATE513549T1 (enExample) |
| CY (1) | CY1115946T1 (enExample) |
| DK (1) | DK2272517T4 (enExample) |
| ES (1) | ES2523266T5 (enExample) |
| MY (1) | MY179032A (enExample) |
| PL (1) | PL2272517T5 (enExample) |
| PT (1) | PT2272517E (enExample) |
| SI (1) | SI2272517T2 (enExample) |
| UY (1) | UY29176A1 (enExample) |
| WO (1) | WO2006046024A1 (enExample) |
Families Citing this family (75)
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|---|---|---|---|---|
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| BRPI1012108B8 (pt) | 2009-05-22 | 2021-05-25 | Incyte Corp | composto 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octa no- ou heptano-nitrila, sua composição, seus usos e processo para preparar um sal de ácido fosfórico |
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| PT2705029T (pt) | 2011-05-04 | 2019-02-01 | Rhizen Pharmaceuticals S A | Novos compostos como moduladores de proteína quinases |
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| CN109316480A (zh) | 2011-07-13 | 2019-02-12 | 赛特凯恩蒂克公司 | 组合als疗法 |
| WO2013023119A1 (en) | 2011-08-10 | 2013-02-14 | Novartis Pharma Ag | JAK P13K/mTOR COMBINATION THERAPY |
| TW201313721A (zh) | 2011-08-18 | 2013-04-01 | Incyte Corp | 作為jak抑制劑之環己基氮雜環丁烷衍生物 |
| UA111854C2 (uk) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | Способи і проміжні сполуки для отримання інгібіторів jak |
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| US7423043B2 (en) | 2005-02-18 | 2008-09-09 | Lexicon Pharmaceuticals, Inc. | 4-Piperidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine compounds |
| US20060281768A1 (en) | 2005-06-10 | 2006-12-14 | Gaul Michael D | Thienopyrimidine and thienopyridine kinase modulators |
| JP5071374B2 (ja) | 2005-07-14 | 2012-11-14 | アステラス製薬株式会社 | ヘテロ環ヤヌスキナーゼ3阻害剤 |
| US20070049591A1 (en) | 2005-08-25 | 2007-03-01 | Kalypsys, Inc. | Inhibitors of MAPK/Erk Kinase |
| WO2007084667A2 (en) | 2006-01-19 | 2007-07-26 | Osi Pharmaceutical, Inc. | Fused heterobicyclic kinase inhibitors |
| EP2037931A2 (en) | 2006-04-25 | 2009-03-25 | Astex Therapeutics Limited | Pharmaceutical combinations of pk inhibitors and other active agents |
| JP2009534456A (ja) | 2006-04-25 | 2009-09-24 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
| JP2009534454A (ja) | 2006-04-25 | 2009-09-24 | アステックス、セラピューティックス、リミテッド | 医薬化合物 |
| WO2007125321A2 (en) | 2006-04-25 | 2007-11-08 | Astex Therapeutics Limited | Purine and deazapurine derivatives as pharmaceutical compounds |
| US20090253718A1 (en) | 2006-04-25 | 2009-10-08 | Astex Therapeutics Limited | Pharmaceutical Compounds |
| AR064416A1 (es) | 2006-12-21 | 2009-04-01 | Cancer Rec Tech Ltd | Derivados de purina, piridina y pirimidina condensadas con heterociclos, moduladores de pka y/o pkb, composiciones farmaceuticas que los contienen, y usos para el tratamiento de enfermedades hiperproliferativas. |
| AR064415A1 (es) | 2006-12-21 | 2009-04-01 | Cancer Rec Tech Ltd | Derivados de pirrolo-piperidinas y purinas,composiciones farmaceuticas que los contienen y usos en trastornos y/o enfermedades mediadas por pka y pkb. |
| BRPI0818533B8 (pt) | 2007-10-11 | 2021-05-25 | Astrazeneca Ab | composto, composição farmacêutica, uso de um composto, e, processo para a preparação de um composto |
-
2005
- 2005-10-21 MY MYPI20054963A patent/MY179032A/en unknown
- 2005-10-24 UY UY29176A patent/UY29176A1/es not_active IP Right Cessation
- 2005-10-25 AT AT05797685T patent/ATE513549T1/de not_active IP Right Cessation
- 2005-10-25 JP JP2007538500A patent/JP5128284B2/ja not_active Expired - Lifetime
- 2005-10-25 ES ES10184485.0T patent/ES2523266T5/es not_active Expired - Lifetime
- 2005-10-25 WO PCT/GB2005/004119 patent/WO2006046024A1/en not_active Ceased
- 2005-10-25 AR ARP050104467 patent/AR051342A1/es active IP Right Grant
- 2005-10-25 EP EP20050797685 patent/EP1812004B1/en not_active Expired - Lifetime
- 2005-10-25 PT PT101844850T patent/PT2272517E/pt unknown
- 2005-10-25 EP EP10184485.0A patent/EP2272517B2/en not_active Expired - Lifetime
- 2005-10-25 PL PL10184485T patent/PL2272517T5/pl unknown
- 2005-10-25 US US11/577,963 patent/US8546407B2/en active Active
- 2005-10-25 DK DK10184485.0T patent/DK2272517T4/da active
- 2005-10-25 SI SI200531910T patent/SI2272517T2/sl unknown
-
2013
- 2013-09-04 US US14/017,814 patent/US8809336B2/en not_active Expired - Lifetime
-
2014
- 2014-06-20 US US14/310,475 patent/US9006430B2/en not_active Expired - Lifetime
- 2014-11-27 CY CY20141100991T patent/CY1115946T1/el unknown
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