JP2008515907A5 - - Google Patents
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- Publication number
- JP2008515907A5 JP2008515907A5 JP2007535801A JP2007535801A JP2008515907A5 JP 2008515907 A5 JP2008515907 A5 JP 2008515907A5 JP 2007535801 A JP2007535801 A JP 2007535801A JP 2007535801 A JP2007535801 A JP 2007535801A JP 2008515907 A5 JP2008515907 A5 JP 2008515907A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- cns
- nervous system
- peripheral nervous
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 25
- 208000015114 central nervous system disease Diseases 0.000 claims 18
- 208000027232 peripheral nervous system disease Diseases 0.000 claims 18
- 208000007882 Gastritis Diseases 0.000 claims 8
- 206010047700 Vomiting Diseases 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 208000024827 Alzheimer disease Diseases 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 7
- 208000035475 disorder Diseases 0.000 claims 7
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 7
- 125000003342 alkenyl group Chemical group 0.000 claims 6
- 239000004480 active ingredient Substances 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 208000019901 Anxiety disease Diseases 0.000 claims 4
- 206010003658 Atrial Fibrillation Diseases 0.000 claims 4
- 208000028698 Cognitive impairment Diseases 0.000 claims 4
- 206010010774 Constipation Diseases 0.000 claims 4
- 208000030814 Eating disease Diseases 0.000 claims 4
- 208000010228 Erectile Dysfunction Diseases 0.000 claims 4
- 208000019454 Feeding and Eating disease Diseases 0.000 claims 4
- 208000032382 Ischaemic stroke Diseases 0.000 claims 4
- 208000019695 Migraine disease Diseases 0.000 claims 4
- 206010028813 Nausea Diseases 0.000 claims 4
- 208000018737 Parkinson disease Diseases 0.000 claims 4
- 208000004756 Respiratory Insufficiency Diseases 0.000 claims 4
- 206010038678 Respiratory depression Diseases 0.000 claims 4
- 206010046543 Urinary incontinence Diseases 0.000 claims 4
- 230000036506 anxiety Effects 0.000 claims 4
- 206010003119 arrhythmia Diseases 0.000 claims 4
- 230000006793 arrhythmia Effects 0.000 claims 4
- 208000010877 cognitive disease Diseases 0.000 claims 4
- 235000014632 disordered eating Nutrition 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 230000030136 gastric emptying Effects 0.000 claims 4
- 208000021302 gastroesophageal reflux disease Diseases 0.000 claims 4
- 201000001881 impotence Diseases 0.000 claims 4
- 206010027599 migraine Diseases 0.000 claims 4
- 230000008693 nausea Effects 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 230000008673 vomiting Effects 0.000 claims 4
- 108091005482 5-HT4 receptors Proteins 0.000 claims 3
- 239000000556 agonist Substances 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 125000005257 alkyl acyl group Chemical group 0.000 claims 3
- 125000005189 alkyl hydroxy group Chemical group 0.000 claims 3
- 125000000304 alkynyl group Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 3
- 125000001188 haloalkyl group Chemical group 0.000 claims 3
- 125000001072 heteroaryl group Chemical group 0.000 claims 3
- 239000000018 receptor agonist Substances 0.000 claims 3
- 229940044601 receptor agonist Drugs 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical group CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 108020003175 receptors Proteins 0.000 claims 2
- WMQSLPSOCLFDNW-UHFFFAOYSA-N 4-hydroxy-n-[1-(2-methylpropyl)piperidin-4-yl]-6-oxo-7-propan-2-ylthieno[2,3-b]pyridine-5-carboxamide Chemical compound C1CN(CC(C)C)CCC1NC(=O)C(C(N1C(C)C)=O)=C(O)C2=C1SC=C2 WMQSLPSOCLFDNW-UHFFFAOYSA-N 0.000 claims 1
- HFPUPAKVVYAMOB-UHFFFAOYSA-N 4-hydroxy-n-[1-(3-hydroxypropyl)piperidin-4-yl]-6-oxo-7-propan-2-ylthieno[2,3-b]pyridine-5-carboxamide Chemical compound O=C1N(C(C)C)C=2SC=CC=2C(O)=C1C(=O)NC1CCN(CCCO)CC1 HFPUPAKVVYAMOB-UHFFFAOYSA-N 0.000 claims 1
- BOWNZMVJDFFHNF-UHFFFAOYSA-N 7-ethyl-4-hydroxy-n-[1-(3-hydroxypropyl)piperidin-4-yl]-6-oxothieno[2,3-b]pyridine-5-carboxamide Chemical compound O=C1N(CC)C=2SC=CC=2C(O)=C1C(=O)NC1CCN(CCCO)CC1 BOWNZMVJDFFHNF-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 208000018522 Gastrointestinal disease Diseases 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 1
- 239000011777 magnesium Substances 0.000 claims 1
- 229910052749 magnesium Inorganic materials 0.000 claims 1
- 125000006431 methyl cyclopropyl group Chemical group 0.000 claims 1
- -1 n- propyl Chemical group 0.000 claims 1
- LFURTMSABUMJRB-UHFFFAOYSA-N n-(1-butylpiperidin-4-yl)-4-hydroxy-6-oxo-7-propan-2-ylthieno[2,3-b]pyridine-5-carboxamide Chemical compound C1CN(CCCC)CCC1NC(=O)C(C(N1C(C)C)=O)=C(O)C2=C1SC=C2 LFURTMSABUMJRB-UHFFFAOYSA-N 0.000 claims 1
- UCUHVVXHTVMEJU-UHFFFAOYSA-N n-(1-ethylpiperidin-4-yl)-4-hydroxy-6-oxo-7-propan-2-ylthieno[2,3-b]pyridine-5-carboxamide Chemical compound C1CN(CC)CCC1NC(=O)C(C(N1C(C)C)=O)=C(O)C2=C1SC=C2 UCUHVVXHTVMEJU-UHFFFAOYSA-N 0.000 claims 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 claims 1
- 125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000002469 receptor inverse agonist Substances 0.000 claims 1
- 239000003523 serotonin 4 antagonist Substances 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 0 *N(c([s]cc1)c1C(O)=C1C(NC2CC*CC2)=O)C1=O Chemical compound *N(c([s]cc1)c1C(O)=C1C(NC2CC*CC2)=O)C1=O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/960,769 US7407966B2 (en) | 2004-10-07 | 2004-10-07 | Thienopyridinone compounds and methods of treatment |
| PCT/US2005/035935 WO2006041985A2 (en) | 2004-10-07 | 2005-10-06 | Thienopyridinone compounds and methods of treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008515907A JP2008515907A (ja) | 2008-05-15 |
| JP2008515907A5 true JP2008515907A5 (enExample) | 2008-11-06 |
Family
ID=35594017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007535801A Pending JP2008515907A (ja) | 2004-10-07 | 2005-10-06 | チエノピリジノン化合物およびその処置方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7407966B2 (enExample) |
| EP (1) | EP1802631A2 (enExample) |
| JP (1) | JP2008515907A (enExample) |
| KR (1) | KR20070106682A (enExample) |
| CN (1) | CN101061123A (enExample) |
| AR (1) | AR052314A1 (enExample) |
| AU (1) | AU2005294329A1 (enExample) |
| BR (1) | BRPI0516130A (enExample) |
| CA (1) | CA2583353A1 (enExample) |
| IL (1) | IL182436A0 (enExample) |
| MA (1) | MA29211B1 (enExample) |
| MX (1) | MX2007004230A (enExample) |
| NO (1) | NO20072348L (enExample) |
| NZ (1) | NZ554927A (enExample) |
| RU (1) | RU2007116950A (enExample) |
| TW (1) | TW200621245A (enExample) |
| WO (1) | WO2006041985A2 (enExample) |
| ZA (1) | ZA200703596B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7612078B2 (en) * | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US20050222175A1 (en) * | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7488736B2 (en) * | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7576211B2 (en) * | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7598265B2 (en) * | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| US7407966B2 (en) | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7968538B2 (en) | 2005-01-25 | 2011-06-28 | Galenea Corp. | Substituted arylamine compounds and methods of treatment |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| EP2445877B1 (en) * | 2008-12-03 | 2014-07-23 | Nanotherapeutics, Inc. | Bicyclic compounds and methods of making and using same |
| ES2578628T3 (es) * | 2009-09-14 | 2016-07-28 | Suven Life Sciences Limited | Compuestos de L-dihidro-2-oxoquinolina como ligandos del receptor de 5-HT4 |
| JP2014076948A (ja) * | 2011-02-09 | 2014-05-01 | Astellas Pharma Inc | イソキノリンアミド誘導体 |
| EP2679591A1 (en) * | 2012-06-29 | 2014-01-01 | Poxel | Thienopyridone derivatives useful as activators of AMPK |
| US9381199B2 (en) | 2012-07-09 | 2016-07-05 | Hetero Research Foundation | Linagliptin solid dispersion |
| EP3628660A1 (en) * | 2018-09-28 | 2020-04-01 | Université de Caen Normandie | Donecopride and flucopride as neuroprotective agents in the treatment of neurodegenerative diseases |
| JP7664491B2 (ja) * | 2022-01-11 | 2025-04-17 | スヴェン・ライフ・サイエンシーズ・リミテッド | ５－ＨＴ４受容体アゴニストとしてのピロロ［１，２－ｂ］－２－ピリダジノン化合物 |
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| US3069412A (en) | 1958-08-15 | 1962-12-18 | Fmc Corp | N-aminoazetidine and preparation thereof |
| CA933923A (en) | 1969-12-19 | 1973-09-18 | Eichenberger Kurt | Process for the manufacture of new thiopyranes |
| GB1570494A (en) | 1975-11-28 | 1980-07-02 | Ici Ltd | Thienopyrimidine derivatives and their use as pesticides |
| DE2925175A1 (de) | 1979-06-22 | 1981-01-08 | Basf Ag | Verfahren zur herstellung von isatosaeureanhydriden |
| IT1203323B (it) | 1987-02-02 | 1989-02-15 | Hoechst Italia Spa | Additivo fotoattivatore per composizioni polimeriche costituito dal sale metallico di una cera ossidata |
| US5236917A (en) | 1989-05-04 | 1993-08-17 | Sterling Winthrop Inc. | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof |
| US5219864A (en) * | 1991-03-12 | 1993-06-15 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
| US5155115A (en) | 1991-03-12 | 1992-10-13 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
| US5227387A (en) | 1991-09-03 | 1993-07-13 | Dowelanco | Quinoline nematicidal method |
| DE4138820A1 (de) | 1991-11-26 | 1993-05-27 | Basf Ag | Chinolin-3-carbonsaeureamide, deren herstellung und verwendung |
| DE4208254A1 (de) | 1992-03-14 | 1993-09-16 | Hoechst Ag | Substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel und fungizid |
| DE4227747A1 (de) * | 1992-08-21 | 1994-02-24 | Basf Ag | Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung |
| US5409948A (en) | 1992-11-23 | 1995-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating cognitive disorders with phenserine |
| JPH06239858A (ja) | 1993-02-16 | 1994-08-30 | Otsuka Pharmaceut Co Ltd | 末梢血管拡張剤 |
| GB9306460D0 (en) | 1993-03-29 | 1993-05-19 | Smithkline Beecham Plc | Novel compounds |
| JPH07324087A (ja) * | 1994-04-04 | 1995-12-12 | Taisho Pharmaceut Co Ltd | 複素環化合物 |
| TW449600B (en) * | 1994-04-19 | 2001-08-11 | Takeda Chemical Industries Ltd | Condensed-ring thiophene derivatives, their production and use |
| JP3829879B2 (ja) | 1994-05-18 | 2006-10-04 | 大正製薬株式会社 | キノリンカルボン酸誘導体 |
| GB2295387A (en) | 1994-11-23 | 1996-05-29 | Glaxo Inc | Quinazoline antagonists of alpha 1c adrenergic receptors |
| DE19636769A1 (de) | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724980A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| JPH11130777A (ja) | 1997-08-13 | 1999-05-18 | Takeda Chem Ind Ltd | チエノピリジン誘導体、その中間体およびそれらの製造法 |
| US6340759B1 (en) * | 1997-10-02 | 2002-01-22 | Eisai Co., Ltd. | Fused pyridine derivatives |
| AU2879799A (en) * | 1998-02-26 | 1999-09-15 | Neurogen Corporation | 4-(4-piperidylmethylamino) substituted heteroaryl fused pyridines: gaba brain receptor ligands |
| DE19815026A1 (de) | 1998-04-03 | 1999-10-07 | Hoechst Schering Agrevo Gmbh | Substituierte Piperidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide |
| US6232320B1 (en) * | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| EP1173168A2 (en) * | 1999-04-28 | 2002-01-23 | Respiratorius AB | Compound for use as a medicament for treatment of disorders involving bronchocontraction |
| SE9902987D0 (sv) | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
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| US20040224927A1 (en) | 2000-06-16 | 2004-11-11 | Trustees Of Tufts College | 7-N-substituted phenyl tetracycline compounds |
| FR2821356A1 (fr) * | 2001-02-23 | 2002-08-30 | Cerep | Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations |
| EP1270568A1 (en) | 2001-06-19 | 2003-01-02 | Biofrontera Pharmaceuticals AG | 1-methyl-4-(3-ethoxy-9h-thioxanthene-ylidene)-piperidine and its use as 5-HT2B and/or H1 antagonist |
| WO2003020728A1 (en) * | 2001-08-30 | 2003-03-13 | Pharmacia & Upjohn Company | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS |
| MXPA03000145A (es) | 2002-01-07 | 2003-07-15 | Pfizer | Compuestos de oxo u oxi-piridina como moduladores de receptores 5-ht4. |
| AU2003298514A1 (en) | 2002-05-17 | 2004-05-04 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| US20040138238A1 (en) | 2002-08-08 | 2004-07-15 | Dhanoa Dale S. | Substituted aminopyrimidine compounds as neurokinin antagonists |
| AU2003255845A1 (en) | 2002-08-22 | 2004-03-11 | Piramed Limited | Phosphadidylinositol 3,5-biphosphate inhibitors as anti-viral agents |
| AU2003277215A1 (en) | 2002-10-01 | 2004-04-23 | Predix Pharmaceuticals Holdings, Inc. | Novel neurokinin antagonists and methods of use thereof |
| US7153858B2 (en) | 2003-01-31 | 2006-12-26 | Epix Delaware, Inc. | Arylpiperazinyl compounds |
| CN1777612A (zh) | 2003-03-31 | 2006-05-24 | 普雷迪克医药品控股公司 | 新的哌啶基氨基－噻吩并[2,3－d]嘧啶化合物 |
| US20050222175A1 (en) | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7612078B2 (en) | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7119205B2 (en) * | 2003-05-16 | 2006-10-10 | Abbott Laboratories | Thienopyridones as AMPK activators for the treatment of diabetes and obesity |
| SI1651234T1 (sl) | 2003-07-25 | 2008-02-29 | Hoffmann La Roche | Kombinacija antagonista mglur2 in inhibitorja ache za zdravljenje akutnih in/ali kronicnih nevroloskih motenj |
| GB0322140D0 (en) | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| EP2338490A3 (en) | 2003-11-03 | 2012-06-06 | Probiodrug AG | Combinations useful for the treatment of neuronal disorders |
| US7488736B2 (en) | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US20060084806A1 (en) | 2004-07-21 | 2006-04-20 | Ramasubramanian Sridharan | Processes for the preparation of imidazo[1,2-a] pyridine derivatives |
| US7407966B2 (en) | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7598265B2 (en) | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| US7576211B2 (en) | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7968538B2 (en) | 2005-01-25 | 2011-06-28 | Galenea Corp. | Substituted arylamine compounds and methods of treatment |
| AU2006317689B2 (en) | 2005-11-23 | 2013-07-25 | Epix Delaware, Inc. | S1P receptor modulating compounds and use thereof |
-
2004
- 2004-10-07 US US10/960,769 patent/US7407966B2/en active Active
-
2005
- 2005-10-06 RU RU2007116950/04A patent/RU2007116950A/ru not_active Application Discontinuation
- 2005-10-06 MX MX2007004230A patent/MX2007004230A/es unknown
- 2005-10-06 WO PCT/US2005/035935 patent/WO2006041985A2/en not_active Ceased
- 2005-10-06 EP EP05801809A patent/EP1802631A2/en not_active Withdrawn
- 2005-10-06 BR BRPI0516130-4A patent/BRPI0516130A/pt not_active IP Right Cessation
- 2005-10-06 JP JP2007535801A patent/JP2008515907A/ja active Pending
- 2005-10-06 AU AU2005294329A patent/AU2005294329A1/en not_active Abandoned
- 2005-10-06 CN CNA2005800391979A patent/CN101061123A/zh active Pending
- 2005-10-06 NZ NZ554927A patent/NZ554927A/en unknown
- 2005-10-06 KR KR1020077008043A patent/KR20070106682A/ko not_active Withdrawn
- 2005-10-06 CA CA002583353A patent/CA2583353A1/en not_active Abandoned
- 2005-10-07 TW TW094135236A patent/TW200621245A/zh unknown
- 2005-10-07 AR ARP050104240A patent/AR052314A1/es unknown
-
2007
- 2007-04-10 IL IL182436A patent/IL182436A0/en unknown
- 2007-05-04 ZA ZA200703596A patent/ZA200703596B/en unknown
- 2007-05-04 MA MA29866A patent/MA29211B1/fr unknown
- 2007-05-07 NO NO20072348A patent/NO20072348L/no not_active Application Discontinuation
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