JP2008515907A - チエノピリジノン化合物およびその処置方法 - Google Patents
チエノピリジノン化合物およびその処置方法 Download PDFInfo
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- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 description 1
- 125000005300 thiocarboxy group Chemical group C(=S)(O)* 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 150000003572 thiolanes Chemical class 0.000 description 1
- 229930192474 thiophene Natural products 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- 125000004784 trichloromethoxy group Chemical group ClC(O*)(Cl)Cl 0.000 description 1
- WUUHFRRPHJEEKV-UHFFFAOYSA-N tripotassium borate Chemical compound [K+].[K+].[K+].[O-]B([O-])[O-] WUUHFRRPHJEEKV-UHFFFAOYSA-N 0.000 description 1
- ZNRGQMMCGHDTEI-ITGUQSILSA-N tropisetron Chemical compound C1=CC=C2C(C(=O)O[C@H]3C[C@H]4CC[C@@H](C3)N4C)=CNC2=C1 ZNRGQMMCGHDTEI-ITGUQSILSA-N 0.000 description 1
- 229960003688 tropisetron Drugs 0.000 description 1
- 238000007039 two-step reaction Methods 0.000 description 1
- 229920001664 tyloxapol Polymers 0.000 description 1
- MDYZKJNTKZIUSK-UHFFFAOYSA-N tyloxapol Chemical compound O=C.C1CO1.CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1 MDYZKJNTKZIUSK-UHFFFAOYSA-N 0.000 description 1
- 229960004224 tyloxapol Drugs 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 235000012431 wafers Nutrition 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Psychology (AREA)
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- Child & Adolescent Psychology (AREA)
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- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US10/960,769 US7407966B2 (en) | 2004-10-07 | 2004-10-07 | Thienopyridinone compounds and methods of treatment |
| PCT/US2005/035935 WO2006041985A2 (en) | 2004-10-07 | 2005-10-06 | Thienopyridinone compounds and methods of treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008515907A true JP2008515907A (ja) | 2008-05-15 |
| JP2008515907A5 JP2008515907A5 (enExample) | 2008-11-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007535801A Pending JP2008515907A (ja) | 2004-10-07 | 2005-10-06 | チエノピリジノン化合物およびその処置方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7407966B2 (enExample) |
| EP (1) | EP1802631A2 (enExample) |
| JP (1) | JP2008515907A (enExample) |
| KR (1) | KR20070106682A (enExample) |
| CN (1) | CN101061123A (enExample) |
| AR (1) | AR052314A1 (enExample) |
| AU (1) | AU2005294329A1 (enExample) |
| BR (1) | BRPI0516130A (enExample) |
| CA (1) | CA2583353A1 (enExample) |
| IL (1) | IL182436A0 (enExample) |
| MA (1) | MA29211B1 (enExample) |
| MX (1) | MX2007004230A (enExample) |
| NO (1) | NO20072348L (enExample) |
| NZ (1) | NZ554927A (enExample) |
| RU (1) | RU2007116950A (enExample) |
| TW (1) | TW200621245A (enExample) |
| WO (1) | WO2006041985A2 (enExample) |
| ZA (1) | ZA200703596B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009515877A (ja) * | 2005-11-10 | 2009-04-16 | エピックス ファーマシューティカルズ，インコーポレイテッド | Ｃｎｓ障害を処置するための組成物および方法 |
| WO2012108490A1 (ja) * | 2011-02-09 | 2012-08-16 | アステラス製薬株式会社 | イソキノリンアミド誘導体 |
| JP2013504561A (ja) * | 2009-09-14 | 2013-02-07 | スベン ライフ サイエンシズ リミティド | ５−ｈｔ４受容体リガンドとしての１，２−ジヒドロ−２−オキソキノリン化合物 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7612078B2 (en) * | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US20050222175A1 (en) * | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7488736B2 (en) * | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7576211B2 (en) * | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7407966B2 (en) | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7968538B2 (en) | 2005-01-25 | 2011-06-28 | Galenea Corp. | Substituted arylamine compounds and methods of treatment |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| EP2445877B1 (en) * | 2008-12-03 | 2014-07-23 | Nanotherapeutics, Inc. | Bicyclic compounds and methods of making and using same |
| EP2679591A1 (en) * | 2012-06-29 | 2014-01-01 | Poxel | Thienopyridone derivatives useful as activators of AMPK |
| US9381199B2 (en) | 2012-07-09 | 2016-07-05 | Hetero Research Foundation | Linagliptin solid dispersion |
| EP3628660A1 (en) * | 2018-09-28 | 2020-04-01 | Université de Caen Normandie | Donecopride and flucopride as neuroprotective agents in the treatment of neurodegenerative diseases |
| JP7664491B2 (ja) * | 2022-01-11 | 2025-04-17 | スヴェン・ライフ・サイエンシーズ・リミテッド | ５－ＨＴ４受容体アゴニストとしてのピロロ［１，２－ｂ］－２－ピリダジノン化合物 |
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2004
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2005
- 2005-10-06 RU RU2007116950/04A patent/RU2007116950A/ru not_active Application Discontinuation
- 2005-10-06 MX MX2007004230A patent/MX2007004230A/es unknown
- 2005-10-06 WO PCT/US2005/035935 patent/WO2006041985A2/en not_active Ceased
- 2005-10-06 EP EP05801809A patent/EP1802631A2/en not_active Withdrawn
- 2005-10-06 BR BRPI0516130-4A patent/BRPI0516130A/pt not_active IP Right Cessation
- 2005-10-06 JP JP2007535801A patent/JP2008515907A/ja active Pending
- 2005-10-06 AU AU2005294329A patent/AU2005294329A1/en not_active Abandoned
- 2005-10-06 CN CNA2005800391979A patent/CN101061123A/zh active Pending
- 2005-10-06 NZ NZ554927A patent/NZ554927A/en unknown
- 2005-10-06 KR KR1020077008043A patent/KR20070106682A/ko not_active Withdrawn
- 2005-10-06 CA CA002583353A patent/CA2583353A1/en not_active Abandoned
- 2005-10-07 TW TW094135236A patent/TW200621245A/zh unknown
- 2005-10-07 AR ARP050104240A patent/AR052314A1/es unknown
-
2007
- 2007-04-10 IL IL182436A patent/IL182436A0/en unknown
- 2007-05-04 ZA ZA200703596A patent/ZA200703596B/en unknown
- 2007-05-04 MA MA29866A patent/MA29211B1/fr unknown
- 2007-05-07 NO NO20072348A patent/NO20072348L/no not_active Application Discontinuation
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0565289A (ja) * | 1991-03-12 | 1993-03-19 | Kyowa Hakko Kogyo Co Ltd | チエノピリジン誘導体 |
| JPH07324087A (ja) * | 1994-04-04 | 1995-12-12 | Taisho Pharmaceut Co Ltd | 複素環化合物 |
| JP2002542287A (ja) * | 1999-04-28 | 2002-12-10 | レスピラトリウス アクチボラゲット | 医 薬 |
| JP2004529106A (ja) * | 2001-02-23 | 2004-09-24 | セレ | 新規なアリールカルバマート誘導体、その製造および使用 |
| JP2003212868A (ja) * | 2002-01-07 | 2003-07-30 | Pfizer Pharmaceuticals Inc | ５−ｈｔ４レセプターモジュレーターとしてのオキソ又はオキシピリジン |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009515877A (ja) * | 2005-11-10 | 2009-04-16 | エピックス ファーマシューティカルズ，インコーポレイテッド | Ｃｎｓ障害を処置するための組成物および方法 |
| JP2013504561A (ja) * | 2009-09-14 | 2013-02-07 | スベン ライフ サイエンシズ リミティド | ５−ｈｔ４受容体リガンドとしての１，２−ジヒドロ−２−オキソキノリン化合物 |
| WO2012108490A1 (ja) * | 2011-02-09 | 2012-08-16 | アステラス製薬株式会社 | イソキノリンアミド誘導体 |
Also Published As
| Publication number | Publication date |
|---|---|
| MA29211B1 (fr) | 2008-02-01 |
| NZ554927A (en) | 2009-07-31 |
| NO20072348L (no) | 2007-07-06 |
| WO2006041985A3 (en) | 2006-07-06 |
| US7407966B2 (en) | 2008-08-05 |
| EP1802631A2 (en) | 2007-07-04 |
| KR20070106682A (ko) | 2007-11-05 |
| CN101061123A (zh) | 2007-10-24 |
| BRPI0516130A (pt) | 2008-08-26 |
| AR052314A1 (es) | 2007-03-14 |
| WO2006041985A2 (en) | 2006-04-20 |
| IL182436A0 (en) | 2007-07-24 |
| CA2583353A1 (en) | 2006-04-20 |
| AU2005294329A1 (en) | 2006-04-20 |
| AU2005294329A2 (en) | 2006-04-20 |
| MX2007004230A (es) | 2007-06-11 |
| US20060079547A1 (en) | 2006-04-13 |
| TW200621245A (en) | 2006-07-01 |
| ZA200703596B (en) | 2008-05-28 |
| RU2007116950A (ru) | 2008-11-20 |
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