AU2005294329A1 - Thienopyridinone compounds and methods of treatment - Google Patents
Thienopyridinone compounds and methods of treatment Download PDFInfo
- Publication number
- AU2005294329A1 AU2005294329A1 AU2005294329A AU2005294329A AU2005294329A1 AU 2005294329 A1 AU2005294329 A1 AU 2005294329A1 AU 2005294329 A AU2005294329 A AU 2005294329A AU 2005294329 A AU2005294329 A AU 2005294329A AU 2005294329 A1 AU2005294329 A1 AU 2005294329A1
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- compound
- disorders
- disease
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- pharmaceutically acceptable
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- 125000005300 thiocarboxy group Chemical group C(=S)(O)* 0.000 description 1
- 229930192474 thiophene Chemical group 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 150000003852 triazoles Chemical group 0.000 description 1
- 125000004784 trichloromethoxy group Chemical group ClC(O*)(Cl)Cl 0.000 description 1
- 206010044652 trigeminal neuralgia Diseases 0.000 description 1
- WUUHFRRPHJEEKV-UHFFFAOYSA-N tripotassium borate Chemical class [K+].[K+].[K+].[O-]B([O-])[O-] WUUHFRRPHJEEKV-UHFFFAOYSA-N 0.000 description 1
- ZNRGQMMCGHDTEI-ITGUQSILSA-N tropisetron Chemical compound C1=CC=C2C(C(=O)O[C@H]3C[C@H]4CC[C@@H](C3)N4C)=CNC2=C1 ZNRGQMMCGHDTEI-ITGUQSILSA-N 0.000 description 1
- 229960003688 tropisetron Drugs 0.000 description 1
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- MDYZKJNTKZIUSK-UHFFFAOYSA-N tyloxapol Chemical compound O=C.C1CO1.CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1 MDYZKJNTKZIUSK-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
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- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Nutrition Science (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/960,769 US7407966B2 (en) | 2004-10-07 | 2004-10-07 | Thienopyridinone compounds and methods of treatment |
| US10/960,769 | 2004-10-07 | ||
| PCT/US2005/035935 WO2006041985A2 (en) | 2004-10-07 | 2005-10-06 | Thienopyridinone compounds and methods of treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2005294329A1 true AU2005294329A1 (en) | 2006-04-20 |
| AU2005294329A2 AU2005294329A2 (en) | 2006-04-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005294329A Abandoned AU2005294329A1 (en) | 2004-10-07 | 2005-10-06 | Thienopyridinone compounds and methods of treatment |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7407966B2 (enExample) |
| EP (1) | EP1802631A2 (enExample) |
| JP (1) | JP2008515907A (enExample) |
| KR (1) | KR20070106682A (enExample) |
| CN (1) | CN101061123A (enExample) |
| AR (1) | AR052314A1 (enExample) |
| AU (1) | AU2005294329A1 (enExample) |
| BR (1) | BRPI0516130A (enExample) |
| CA (1) | CA2583353A1 (enExample) |
| IL (1) | IL182436A0 (enExample) |
| MA (1) | MA29211B1 (enExample) |
| MX (1) | MX2007004230A (enExample) |
| NO (1) | NO20072348L (enExample) |
| NZ (1) | NZ554927A (enExample) |
| RU (1) | RU2007116950A (enExample) |
| TW (1) | TW200621245A (enExample) |
| WO (1) | WO2006041985A2 (enExample) |
| ZA (1) | ZA200703596B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7612078B2 (en) * | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US20050222175A1 (en) * | 2004-03-31 | 2005-10-06 | Dhanoa Dale S | New piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7488736B2 (en) * | 2004-05-17 | 2009-02-10 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7576211B2 (en) * | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7598265B2 (en) * | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| US7407966B2 (en) | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| RU2440996C2 (ru) | 2005-01-25 | 2012-01-27 | Галенеа Корп. | Замещенные ариламины и их применение в качестве модуляторов 5-ht6-рецептора |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| WO2010065743A2 (en) * | 2008-12-03 | 2010-06-10 | Nanotherapeutics, Inc. | Bicyclic compounds and methods of making and using same |
| CN102639526B (zh) * | 2009-09-14 | 2014-06-04 | 苏文生命科学有限公司 | 作为5-ht4受体配体的1,2-二氢-2-氧代喹啉化合物 |
| JP2014076948A (ja) * | 2011-02-09 | 2014-05-01 | Astellas Pharma Inc | イソキノリンアミド誘導体 |
| EP2679591A1 (en) * | 2012-06-29 | 2014-01-01 | Poxel | Thienopyridone derivatives useful as activators of AMPK |
| US9381199B2 (en) | 2012-07-09 | 2016-07-05 | Hetero Research Foundation | Linagliptin solid dispersion |
| EP3628660A1 (en) * | 2018-09-28 | 2020-04-01 | Université de Caen Normandie | Donecopride and flucopride as neuroprotective agents in the treatment of neurodegenerative diseases |
| AU2023207844B2 (en) * | 2022-01-11 | 2025-02-20 | Suven Life Sciences Limited | PYRROLO[1,2-b]-2-PYRIDAZINONE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS |
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| US3069412A (en) * | 1958-08-15 | 1962-12-18 | Fmc Corp | N-aminoazetidine and preparation thereof |
| CA933923A (en) * | 1969-12-19 | 1973-09-18 | Eichenberger Kurt | Process for the manufacture of new thiopyranes |
| GB1570494A (en) * | 1975-11-28 | 1980-07-02 | Ici Ltd | Thienopyrimidine derivatives and their use as pesticides |
| DE2925175A1 (de) * | 1979-06-22 | 1981-01-08 | Basf Ag | Verfahren zur herstellung von isatosaeureanhydriden |
| IT1203323B (it) * | 1987-02-02 | 1989-02-15 | Hoechst Italia Spa | Additivo fotoattivatore per composizioni polimeriche costituito dal sale metallico di una cera ossidata |
| US5236917A (en) * | 1989-05-04 | 1993-08-17 | Sterling Winthrop Inc. | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof |
| US5155115A (en) * | 1991-03-12 | 1992-10-13 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
| US5219864A (en) | 1991-03-12 | 1993-06-15 | Kyowa Hakko Kogyo Co., Ltd. | Thienopyridine derivatives |
| US5227387A (en) * | 1991-09-03 | 1993-07-13 | Dowelanco | Quinoline nematicidal method |
| DE4138820A1 (de) * | 1991-11-26 | 1993-05-27 | Basf Ag | Chinolin-3-carbonsaeureamide, deren herstellung und verwendung |
| DE4208254A1 (de) * | 1992-03-14 | 1993-09-16 | Hoechst Ag | Substituierte pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel und fungizid |
| DE4227747A1 (de) * | 1992-08-21 | 1994-02-24 | Basf Ag | Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung |
| US5409948A (en) | 1992-11-23 | 1995-04-25 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating cognitive disorders with phenserine |
| JPH06239858A (ja) * | 1993-02-16 | 1994-08-30 | Otsuka Pharmaceut Co Ltd | 末梢血管拡張剤 |
| GB9306460D0 (en) | 1993-03-29 | 1993-05-19 | Smithkline Beecham Plc | Novel compounds |
| JPH07324087A (ja) * | 1994-04-04 | 1995-12-12 | Taisho Pharmaceut Co Ltd | 複素環化合物 |
| TW449600B (en) * | 1994-04-19 | 2001-08-11 | Takeda Chemical Industries Ltd | Condensed-ring thiophene derivatives, their production and use |
| JP3829879B2 (ja) | 1994-05-18 | 2006-10-04 | 大正製薬株式会社 | キノリンカルボン酸誘導体 |
| GB2295387A (en) | 1994-11-23 | 1996-05-29 | Glaxo Inc | Quinazoline antagonists of alpha 1c adrenergic receptors |
| DE19636769A1 (de) * | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724980A1 (de) * | 1997-06-13 | 1998-12-17 | Basf Ag | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
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| WO2001025218A1 (en) | 1999-10-01 | 2001-04-12 | Japan Energy Corporation | Novel quinazoline derivatives |
| US20040224927A1 (en) * | 2000-06-16 | 2004-11-11 | Trustees Of Tufts College | 7-N-substituted phenyl tetracycline compounds |
| FR2821356A1 (fr) * | 2001-02-23 | 2002-08-30 | Cerep | Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations |
| EP1270568A1 (en) | 2001-06-19 | 2003-01-02 | Biofrontera Pharmaceuticals AG | 1-methyl-4-(3-ethoxy-9h-thioxanthene-ylidene)-piperidine and its use as 5-HT2B and/or H1 antagonist |
| WO2003020728A1 (en) * | 2001-08-30 | 2003-03-13 | Pharmacia & Upjohn Company | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS |
| MXPA03000145A (es) * | 2002-01-07 | 2003-07-15 | Pfizer | Compuestos de oxo u oxi-piridina como moduladores de receptores 5-ht4. |
| WO2004034963A2 (en) | 2002-05-17 | 2004-04-29 | Eisai Co., Ltd. | Methods and compositions using cholinesterase inhibitors |
| US20040138238A1 (en) | 2002-08-08 | 2004-07-15 | Dhanoa Dale S. | Substituted aminopyrimidine compounds as neurokinin antagonists |
| AU2003255845A1 (en) | 2002-08-22 | 2004-03-11 | Piramed Limited | Phosphadidylinositol 3,5-biphosphate inhibitors as anti-viral agents |
| WO2004030629A2 (en) | 2002-10-01 | 2004-04-15 | Predix Pharmaceuticals | Novel neurokinin antagonists and methods of use thereof |
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| NZ542236A (en) | 2003-03-31 | 2008-05-30 | Predix Pharmaceuticals Holding | New piperidinylamino-thieno[2,3-d]pyrimidine compounds |
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| US7612078B2 (en) * | 2003-03-31 | 2009-11-03 | Epix Delaware, Inc. | Piperidinylamino-thieno[2,3-D] pyrimidine compounds |
| US7119205B2 (en) * | 2003-05-16 | 2006-10-10 | Abbott Laboratories | Thienopyridones as AMPK activators for the treatment of diabetes and obesity |
| RU2357734C2 (ru) * | 2003-07-25 | 2009-06-10 | Ф.Хоффманн-Ля Рош Аг | КОМБИНАЦИЯ АНТАГОНИСТА РЕЦЕПТОРА mGluR2 И ИНГИБИТОРА ФЕРМЕНТА AChE ДЛЯ ЛЕЧЕНИЯ ОСТРЫХ И/ИЛИ ХРОНИЧЕСКИХ НЕВРОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ |
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| NZ546887A (en) * | 2003-11-03 | 2009-04-30 | Probiodrug Ag | Combinations useful for the treatment of neuronal disorders |
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| US7407966B2 (en) | 2004-10-07 | 2008-08-05 | Epix Delaware, Inc. | Thienopyridinone compounds and methods of treatment |
| US7576211B2 (en) * | 2004-09-30 | 2009-08-18 | Epix Delaware, Inc. | Synthesis of thienopyridinone compounds and related intermediates |
| US7598265B2 (en) * | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| RU2440996C2 (ru) * | 2005-01-25 | 2012-01-27 | Галенеа Корп. | Замещенные ариламины и их применение в качестве модуляторов 5-ht6-рецептора |
| JP2009520688A (ja) * | 2005-11-23 | 2009-05-28 | エピックス デラウェア， インコーポレイテッド | Ｓ１ｐ受容体調節化合物およびそれらの使用 |
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2004
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-
2005
- 2005-10-06 WO PCT/US2005/035935 patent/WO2006041985A2/en not_active Ceased
- 2005-10-06 AU AU2005294329A patent/AU2005294329A1/en not_active Abandoned
- 2005-10-06 NZ NZ554927A patent/NZ554927A/en unknown
- 2005-10-06 MX MX2007004230A patent/MX2007004230A/es unknown
- 2005-10-06 JP JP2007535801A patent/JP2008515907A/ja active Pending
- 2005-10-06 EP EP05801809A patent/EP1802631A2/en not_active Withdrawn
- 2005-10-06 KR KR1020077008043A patent/KR20070106682A/ko not_active Withdrawn
- 2005-10-06 CN CNA2005800391979A patent/CN101061123A/zh active Pending
- 2005-10-06 CA CA002583353A patent/CA2583353A1/en not_active Abandoned
- 2005-10-06 RU RU2007116950/04A patent/RU2007116950A/ru not_active Application Discontinuation
- 2005-10-06 BR BRPI0516130-4A patent/BRPI0516130A/pt not_active IP Right Cessation
- 2005-10-07 TW TW094135236A patent/TW200621245A/zh unknown
- 2005-10-07 AR ARP050104240A patent/AR052314A1/es unknown
-
2007
- 2007-04-10 IL IL182436A patent/IL182436A0/en unknown
- 2007-05-04 MA MA29866A patent/MA29211B1/fr unknown
- 2007-05-04 ZA ZA200703596A patent/ZA200703596B/en unknown
- 2007-05-07 NO NO20072348A patent/NO20072348L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007004230A (es) | 2007-06-11 |
| NZ554927A (en) | 2009-07-31 |
| TW200621245A (en) | 2006-07-01 |
| CN101061123A (zh) | 2007-10-24 |
| US20060079547A1 (en) | 2006-04-13 |
| BRPI0516130A (pt) | 2008-08-26 |
| JP2008515907A (ja) | 2008-05-15 |
| US7407966B2 (en) | 2008-08-05 |
| KR20070106682A (ko) | 2007-11-05 |
| RU2007116950A (ru) | 2008-11-20 |
| ZA200703596B (en) | 2008-05-28 |
| IL182436A0 (en) | 2007-07-24 |
| WO2006041985A2 (en) | 2006-04-20 |
| NO20072348L (no) | 2007-07-06 |
| EP1802631A2 (en) | 2007-07-04 |
| WO2006041985A3 (en) | 2006-07-06 |
| AR052314A1 (es) | 2007-03-14 |
| MA29211B1 (fr) | 2008-02-01 |
| AU2005294329A2 (en) | 2006-04-20 |
| CA2583353A1 (en) | 2006-04-20 |
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| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 29 JUN 2007 Free format text: THE NATURE OF THE AMENDMENT IS: ADD CO-INVENTOR CHEN, DONGLI |
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| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |