JP2008513474A - 下痢を予防するかまたは治療する方法及び組成物 - Google Patents
下痢を予防するかまたは治療する方法及び組成物 Download PDFInfo
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- JP2008513474A JP2008513474A JP2007532483A JP2007532483A JP2008513474A JP 2008513474 A JP2008513474 A JP 2008513474A JP 2007532483 A JP2007532483 A JP 2007532483A JP 2007532483 A JP2007532483 A JP 2007532483A JP 2008513474 A JP2008513474 A JP 2008513474A
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
- H04L25/00—Baseband systems
- H04L25/02—Details ; arrangements for supplying electrical power along data transmission lines
- H04L25/03—Shaping networks in transmitter or receiver, e.g. adaptive shaping networks
- H04L25/03828—Arrangements for spectral shaping; Arrangements for providing signals with specified spectral properties
- H04L25/03834—Arrangements for spectral shaping; Arrangements for providing signals with specified spectral properties using pulse shaping
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04L—TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
- H04L27/00—Modulated-carrier systems
- H04L27/18—Phase-modulated carrier systems, i.e. using phase-shift keying
- H04L27/20—Modulator circuits; Transmitter circuits
- H04L27/2003—Modulator circuits; Transmitter circuits for continuous phase modulation
- H04L27/2007—Modulator circuits; Transmitter circuits for continuous phase modulation in which the phase change within each symbol period is constrained
- H04L27/2017—Modulator circuits; Transmitter circuits for continuous phase modulation in which the phase change within each symbol period is constrained in which the phase changes are non-linear, e.g. generalized and Gaussian minimum shift keying, tamed frequency modulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Physics & Mathematics (AREA)
- Computer Networks & Wireless Communication (AREA)
- Signal Processing (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Nonlinear Science (AREA)
- Power Engineering (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/942,397 US8685943B2 (en) | 2003-03-12 | 2004-09-16 | Methods for reducing diarrhea in a companion animal |
| PCT/US2005/033077 WO2006032005A2 (en) | 2004-09-16 | 2005-09-16 | Method and composition for preventing or treating diarrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008513474A true JP2008513474A (ja) | 2008-05-01 |
| JP2008513474A5 JP2008513474A5 (enExample) | 2008-10-30 |
Family
ID=36060717
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007532483A Pending JP2008513474A (ja) | 2004-09-16 | 2005-09-16 | 下痢を予防するかまたは治療する方法及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8685943B2 (enExample) |
| EP (1) | EP1796728A4 (enExample) |
| JP (1) | JP2008513474A (enExample) |
| CN (2) | CN101060861B (enExample) |
| AU (1) | AU2005284784B2 (enExample) |
| BR (1) | BRPI0515376A (enExample) |
| CA (1) | CA2581020C (enExample) |
| RU (2) | RU2563137C2 (enExample) |
| WO (1) | WO2006032005A2 (enExample) |
| ZA (1) | ZA200703100B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102271531A (zh) * | 2009-01-06 | 2011-12-07 | 雀巢产品技术援助有限公司 | 果冻食物组合物中的块状物 |
| JP5554350B2 (ja) * | 2009-03-11 | 2014-07-23 | ネステク ソシエテ アノニム | 具材入り肉汁食品組成物 |
| EP2588544A1 (fr) * | 2010-07-02 | 2013-05-08 | Ifremer (Institut Français De Recherche Pour L'Exploitation De La Mer) | Exopolysaccharides pour la prévention et la lutte contre la formation de biofilms |
| EP2797426A1 (en) * | 2011-12-29 | 2014-11-05 | Hill's Pet Nutrition, Inc. | Compositions and methods for modifying gastrointestinal flora |
| JP6452616B2 (ja) * | 2012-12-04 | 2019-01-16 | ネステク ソシエテ アノニム | 擬似ローフ食品組成物 |
| GB201519854D0 (en) * | 2015-11-10 | 2015-12-23 | Mars Inc | Pet food |
| CN107296815A (zh) * | 2017-06-29 | 2017-10-27 | 中国人民解放军第二军医大学 | 酵母多糖在制备防护急性放射性骨髓损伤药物中的应用 |
| US11622974B2 (en) | 2019-01-18 | 2023-04-11 | C.P. Kelco U.S., Inc. | Prebiotic composition and its use |
| RU2740380C1 (ru) * | 2019-12-24 | 2021-01-13 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Биоинженерная конструкция на основе бактериального альгината и пробиотических бактерий и способ ее получения |
| TWI840668B (zh) * | 2021-05-13 | 2024-05-01 | 陳昭誠 | 由β-1-4-葡聚醣形成之纖維於製備用於治療腸躁症之組成物之用途 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02289520A (ja) * | 1989-02-09 | 1990-11-29 | Hayashibara Biochem Lab Inc | ビフィズス菌増殖促進剤 |
| JP2004523241A (ja) * | 2001-03-07 | 2004-08-05 | プロバイオニック コーポレイション | プロバイオティクスとして有用な新規ラクトバチルス・ロイテリ(Lactobacillusreuteri) |
| JP2006519863A (ja) * | 2003-03-12 | 2006-08-31 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | 下痢を予防するかまたは低減する方法及び組成物 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1501484A (en) * | 1975-10-24 | 1978-02-15 | Tate & Lyle Ltd | Icing mixture |
| US4410551A (en) * | 1980-05-15 | 1983-10-18 | Ralston Purina Company | Gravy forming intermediate moisture pet food |
| GB8512345D0 (en) * | 1985-05-15 | 1985-06-19 | Scras | Anti-diarrhea compositions |
| US4647470A (en) * | 1985-11-27 | 1987-03-03 | Merck & Co., Inc. | Low-acetyl gellan gum blends |
| US4822626A (en) * | 1987-01-05 | 1989-04-18 | Nabisco Brands, Inc. | Coated canine biscuits |
| GB8710704D0 (en) | 1987-05-06 | 1987-06-10 | Mars G B Ltd | Edible gels |
| EP0291228B1 (en) | 1987-05-14 | 1991-08-28 | Merck & Co. Inc. | Gellan gum/starch blends |
| JPH01193388A (ja) | 1987-10-09 | 1989-08-03 | Agency Of Ind Science & Technol | リオトロピック液晶セル |
| JP2769707B2 (ja) | 1988-11-28 | 1998-06-25 | 大洋香料株式会社 | 透明水性ゲル状芳香剤組成物 |
| DE69112260T2 (de) | 1990-04-23 | 1996-04-11 | Monsanto Co | Gellan-Gummi-Fasern. |
| IT1248934B (it) | 1990-06-01 | 1995-02-11 | Fidia Spa | Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle |
| US5079024A (en) * | 1990-09-25 | 1992-01-07 | Kraft General Foods, Inc. | Method of manufacture of a non-fat cream cheese product |
| US5158800A (en) * | 1991-10-08 | 1992-10-27 | Merck & Co., Inc. | Non-sticky, fat-containing confection |
| JPH0690707A (ja) * | 1992-01-06 | 1994-04-05 | Asahi Chem Ind Co Ltd | 緩下作用の改善された食物繊維組成物 |
| US5292534A (en) * | 1992-03-25 | 1994-03-08 | Valentine Enterprises, Inc. | Sustained release composition and method utilizing xanthan gum and an active ingredient |
| US5419283A (en) * | 1992-04-08 | 1995-05-30 | Ciuffo Gatto S.R.L. | Animal chew toy of starch material and degradable ethylene copolymer |
| US5380522A (en) * | 1992-08-11 | 1995-01-10 | Day; Charles E. | Method for treatment of irritable bowel syndrome |
| US5372829A (en) * | 1993-01-15 | 1994-12-13 | Merck & Co., Inc. | Process for preparing low-fat fried food |
| CA2125914A1 (en) | 1993-06-25 | 1994-12-26 | Pharmacia Corporation | Oil-coated microparticulated gellan gum |
| US5339771A (en) * | 1993-09-15 | 1994-08-23 | Axelrod Herbert R | Animal chew toy containing animal meal |
| US5571545A (en) * | 1994-02-22 | 1996-11-05 | Fuji Oil Company, Limited | Hamburger type food material and process of making it |
| US5616569A (en) * | 1994-03-28 | 1997-04-01 | The Iams Company | Pet food product containing fermentable fibers and process for treating gastrointestinal disorders |
| US5534286A (en) | 1994-06-01 | 1996-07-09 | Monsanto Company | No-fat gellan gum spread |
| US5456937A (en) * | 1994-06-24 | 1995-10-10 | Chalupa; William F. | Gellan gum flavor beads |
| US5596084A (en) * | 1994-10-05 | 1997-01-21 | Monsanto Company | Alginate gels |
| JPH08157377A (ja) * | 1994-12-02 | 1996-06-18 | Nippon Oil Co Ltd | 家畜等の下痢予防・治療剤 |
| JP3836893B2 (ja) * | 1995-01-24 | 2006-10-25 | アボットジャパン株式会社 | ポリカルボフィルカルシウム含有製剤 |
| US5827526A (en) * | 1995-07-11 | 1998-10-27 | Abbott Laboratories | Use of indigestible oligosaccharides to prevent gastrointestinal infections and reduce duration of diarrhea in humans |
| JPH09172980A (ja) * | 1995-12-28 | 1997-07-08 | Ajinomoto Co Inc | 新規リン酸アミノ酸複合塩及び水溶性高分子を含有する反すう動物用飼料添加組成物 |
| JP3955112B2 (ja) | 1996-01-10 | 2007-08-08 | エステー化学株式会社 | ゲル状脱臭剤 |
| JPH09194393A (ja) * | 1996-01-22 | 1997-07-29 | Meiji Milk Prod Co Ltd | 免疫寛容を誘導する方法、免疫寛容誘導食品キットおよび免疫寛容誘導剤キット |
| JPH09201170A (ja) | 1996-01-24 | 1997-08-05 | Dainippon Pharmaceut Co Ltd | ジェランガム含有α化澱粉 |
| JPH09275973A (ja) | 1996-04-12 | 1997-10-28 | Suzuki Motor Corp | 微生物用培地 |
| GB2314840B (en) | 1996-06-28 | 2000-09-06 | Johnson & Johnson Medical | Oxidized oligosaccharides and pharmaceutical compositions |
| JPH1067625A (ja) | 1996-08-22 | 1998-03-10 | Lion Corp | 口腔用組成物 |
| JPH10179050A (ja) | 1996-12-27 | 1998-07-07 | Sanei Gen F F I Inc | ネイティブジェランガムを含有する食品 |
| US6458404B1 (en) * | 1996-08-27 | 2002-10-01 | San-Ei Gen F.F.I., Inc. | Dehydrated gel composition from hydrated isolated acetylated gellan gum |
| US5869118A (en) * | 1996-11-13 | 1999-02-09 | Abbott Laboratories | Gellan gum to improve physical stability of liquid nutritional products |
| US5895804A (en) * | 1997-10-27 | 1999-04-20 | National Starch And Chemical Investment Holding Corporation | Thermosetting polysaccharides |
| JP3874560B2 (ja) | 1998-01-09 | 2007-01-31 | 旭化成ケミカルズ株式会社 | 微細セルロース含有複合物 |
| TW408153B (en) | 1998-01-09 | 2000-10-11 | Asahi Chemical Ind | Cellulose-containing composite, process for its preparation and use thereof |
| JP2002517568A (ja) | 1998-06-10 | 2002-06-18 | モンサント・ピーエルシー | 改質ゲランガム組成物、その調製工程およびその用途 |
| JP3633942B2 (ja) | 1998-09-09 | 2005-03-30 | キユーピー株式会社 | 嘔吐予防食品 |
| US6242035B1 (en) | 1998-11-23 | 2001-06-05 | Cp Kelco U.S., Inc. | Reduced molecular weight native gellan gum |
| NL1013175C2 (nl) | 1999-09-29 | 2001-03-30 | Nutricia Nv | Voedingssamenstellingen die niet-verteerbare polysacchariden bevatten en gebruik ervan voor het verminderen van transport door tight junctions. |
| US6280779B1 (en) * | 1999-12-28 | 2001-08-28 | Colgate-Palmolive Company | Pet food for maintaining normal bowel health |
| US6410079B2 (en) * | 1999-12-28 | 2002-06-25 | Hill's Pet Nutrition, Inc. | High meat pet food compositions |
| US6426195B1 (en) * | 2000-03-28 | 2002-07-30 | Biogenex Lab | Method for silver staining a pathologic sample |
| JP2001269125A (ja) | 2000-03-29 | 2001-10-02 | Nihon Nosan Kogyo Kk | 豚用飼料 |
| EP1250851A1 (en) * | 2001-04-18 | 2002-10-23 | Societe Des Produits Nestle S.A. | Pet food composition containing semi-refined gelling agent |
| NZ515869A (en) | 2001-11-30 | 2003-09-26 | Med Chem Ingredients Ltd | Compositions and methods for animal treatment comprising gluco- and isomalto- oligosaccharides |
| JP2003210075A (ja) * | 2002-01-21 | 2003-07-29 | Nippon Flour Mills Co Ltd | 釣用疑似餌、その製造方法及び釣用疑似餌の製造用キット |
| GB0203431D0 (en) | 2002-02-13 | 2002-04-03 | Mars Inc | Gel |
| JP2003259817A (ja) | 2002-03-08 | 2003-09-16 | Takeo Co Ltd | ペット用冷菓組成物、それを用いたペット用冷菓およびペット用冷菓の製造方法 |
| CN1395938A (zh) * | 2002-09-03 | 2003-02-12 | 林斌 | 一种含低聚果糖的兽用口服液制剂 |
| US7455869B2 (en) * | 2002-12-19 | 2008-11-25 | San-Ei Gen F.F.I., Inc. | Composition for preparing artificial fruit flesh and food product containing the same |
| US20040168951A1 (en) | 2003-02-27 | 2004-09-02 | Mackie Robert W. | Method and system for self administration of medications |
| US20050004071A1 (en) * | 2003-04-21 | 2005-01-06 | Comper Wayne D. | Charged polysaccharides resistant to lysosomal degradation during kidney filtration and renal passage and their use to treat or prevent infection by coronaviruses |
| CA2530843A1 (en) | 2003-07-01 | 2005-01-20 | Todd Maibach | Film comprising therapeutic agents |
| US20050119222A1 (en) | 2003-12-01 | 2005-06-02 | The Iams Company | Compositions comprising fermentable fiber which are adapted for use by a companion animal and kits and methods of their use |
-
2004
- 2004-09-16 US US10/942,397 patent/US8685943B2/en not_active Expired - Lifetime
-
2005
- 2005-09-16 RU RU2010135601/15A patent/RU2563137C2/ru not_active IP Right Cessation
- 2005-09-16 JP JP2007532483A patent/JP2008513474A/ja active Pending
- 2005-09-16 CN CN200580039219.1A patent/CN101060861B/zh not_active Expired - Fee Related
- 2005-09-16 CN CN201610289207.4A patent/CN105878267A/zh active Pending
- 2005-09-16 BR BRPI0515376-0A patent/BRPI0515376A/pt not_active IP Right Cessation
- 2005-09-16 CA CA2581020A patent/CA2581020C/en not_active Expired - Fee Related
- 2005-09-16 RU RU2007114054/14A patent/RU2007114054A/ru not_active Application Discontinuation
- 2005-09-16 WO PCT/US2005/033077 patent/WO2006032005A2/en not_active Ceased
- 2005-09-16 AU AU2005284784A patent/AU2005284784B2/en not_active Ceased
- 2005-09-16 EP EP05797991A patent/EP1796728A4/en not_active Ceased
-
2007
- 2007-04-16 ZA ZA2007/03100A patent/ZA200703100B/en unknown
-
2008
- 2008-03-17 US US12/049,546 patent/US8563029B2/en not_active Expired - Fee Related
-
2014
- 2014-02-24 US US14/188,054 patent/US9028861B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02289520A (ja) * | 1989-02-09 | 1990-11-29 | Hayashibara Biochem Lab Inc | ビフィズス菌増殖促進剤 |
| JP2004523241A (ja) * | 2001-03-07 | 2004-08-05 | プロバイオニック コーポレイション | プロバイオティクスとして有用な新規ラクトバチルス・ロイテリ(Lactobacillusreuteri) |
| JP2006519863A (ja) * | 2003-03-12 | 2006-08-31 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | 下痢を予防するかまたは低減する方法及び組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8685943B2 (en) | 2014-04-01 |
| BRPI0515376A (pt) | 2008-07-22 |
| CN101060861A (zh) | 2007-10-24 |
| CN101060861B (zh) | 2016-06-01 |
| EP1796728A4 (en) | 2008-07-23 |
| US20080160164A1 (en) | 2008-07-03 |
| RU2563137C2 (ru) | 2015-09-20 |
| CA2581020A1 (en) | 2006-03-23 |
| AU2005284784A1 (en) | 2006-03-23 |
| WO2006032005A2 (en) | 2006-03-23 |
| ZA200703100B (en) | 2015-09-30 |
| AU2005284784B2 (en) | 2010-12-16 |
| RU2007114054A (ru) | 2008-10-27 |
| CN105878267A (zh) | 2016-08-24 |
| RU2010135601A (ru) | 2012-02-27 |
| US20050042260A1 (en) | 2005-02-24 |
| US8563029B2 (en) | 2013-10-22 |
| US20140171386A1 (en) | 2014-06-19 |
| EP1796728A2 (en) | 2007-06-20 |
| WO2006032005A3 (en) | 2006-10-19 |
| US9028861B2 (en) | 2015-05-12 |
| CA2581020C (en) | 2016-06-14 |
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