JP2008513464A5 - - Google Patents

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Publication number
JP2008513464A5
JP2008513464A5 JP2007532443A JP2007532443A JP2008513464A5 JP 2008513464 A5 JP2008513464 A5 JP 2008513464A5 JP 2007532443 A JP2007532443 A JP 2007532443A JP 2007532443 A JP2007532443 A JP 2007532443A JP 2008513464 A5 JP2008513464 A5 JP 2008513464A5
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JP
Japan
Prior art keywords
phenyl
pyrazol
optionally substituted
urea
methylpiperazin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007532443A
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English (en)
Japanese (ja)
Other versions
JP2008513464A (ja
JP5063351B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/032839 external-priority patent/WO2006033943A2/en
Publication of JP2008513464A publication Critical patent/JP2008513464A/ja
Publication of JP2008513464A5 publication Critical patent/JP2008513464A5/ja
Application granted granted Critical
Publication of JP5063351B2 publication Critical patent/JP5063351B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007532443A 2004-09-17 2005-09-15 ピラゾールキナーゼモジュレーターおよび使用方法 Expired - Fee Related JP5063351B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61068904P 2004-09-17 2004-09-17
US60/610,689 2004-09-17
PCT/US2005/032839 WO2006033943A2 (en) 2004-09-17 2005-09-15 Pyrazole kinase modulators and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012112312A Division JP2012153720A (ja) 2004-09-17 2012-05-16 ピラゾールキナーゼモジュレーターおよび使用方法

Publications (3)

Publication Number Publication Date
JP2008513464A JP2008513464A (ja) 2008-05-01
JP2008513464A5 true JP2008513464A5 (enExample) 2008-11-06
JP5063351B2 JP5063351B2 (ja) 2012-10-31

Family

ID=36090487

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007532443A Expired - Fee Related JP5063351B2 (ja) 2004-09-17 2005-09-15 ピラゾールキナーゼモジュレーターおよび使用方法
JP2012112312A Withdrawn JP2012153720A (ja) 2004-09-17 2012-05-16 ピラゾールキナーゼモジュレーターおよび使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012112312A Withdrawn JP2012153720A (ja) 2004-09-17 2012-05-16 ピラゾールキナーゼモジュレーターおよび使用方法

Country Status (6)

Country Link
US (1) US8710038B2 (enExample)
EP (1) EP1797072A4 (enExample)
JP (2) JP5063351B2 (enExample)
AU (1) AU2005287170B2 (enExample)
CA (1) CA2579313A1 (enExample)
WO (1) WO2006033943A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1804799B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CA2580856A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
EP2029138A1 (en) 2005-06-03 2009-03-04 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
CN101058561B (zh) * 2006-04-19 2011-01-26 苏州爱斯鹏药物研发有限责任公司 用于抑制蛋白激酶的二苯脲衍生物及其组合物和用途
JP5504259B2 (ja) * 2008-05-19 2014-05-28 メルク・シャープ・アンド・ドーム・コーポレーション 第ｉｘａ因子阻害剤としての複素環式化合物
AU2009289649B2 (en) 2008-09-03 2016-05-05 Biomarin Pharmaceutical Inc. Compositions including 6-aminohexanoic acid derivatives as HDAC inhibitors
US8329757B2 (en) * 2008-10-14 2012-12-11 Charlesson, Llc Curcumin analog compositions and related methods
CN102884059B (zh) 2010-03-11 2015-08-26 大日本住友制药株式会社 N-酰基环胺衍生物或其可药用盐
ES2555260T3 (es) 2010-06-15 2015-12-30 Bayer Intellectual Property Gmbh Derivados de diamida de ácido antranílico
US10059723B2 (en) 2011-02-28 2018-08-28 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
WO2012118782A1 (en) 2011-02-28 2012-09-07 Repligen Corporation Histone deacetylase inhibitors
US8957066B2 (en) 2011-02-28 2015-02-17 Biomarin Pharmaceutical Inc. Histone deacetylase inhibitors
KR101952222B1 (ko) * 2011-04-11 2019-02-26 그린 테크 가부시키가이샤 신규 피라졸 유도체
JP6105594B2 (ja) 2011-09-30 2017-03-29 エンドゥ ファーマシューティカルズ，インコーポレイティド 癌処置用ｃｙｐ１７阻害剤としてのイミダゾール誘導体
JP6130383B2 (ja) 2011-09-30 2017-05-17 エンドゥ ファーマシューティカルズ，インコーポレイティド ピリジン誘導体
WO2014057772A1 (ja) 2012-10-10 2014-04-17 株式会社ファルマエイト 新規ピラゾール誘導体
PL403149A1 (pl) * 2013-03-14 2014-09-15 Celon Pharma Spółka Akcyjna Nowe związki pochodne pirazolilobenzo[d]imidazolu
RU2665554C2 (ru) 2013-03-15 2018-08-31 Байомарин Фармасьютикал Инк. Ингибиторы hdac
EP2944635B1 (en) * 2014-05-15 2018-11-28 Council of Scientific & Industrial Research Pyrazole linked benzimidazole conjugates and a process for preparation thereof
GB201506660D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
GB201506658D0 (en) 2015-04-20 2015-06-03 Cellcentric Ltd Pharmaceutical compounds
EP3643705A1 (en) * 2018-10-24 2020-04-29 Basf Se Pesticidal compounds
WO2022186362A1 (ja) * 2021-03-03 2022-09-09 白鳥製薬株式会社 ピラゾール化合物の製造方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE923028C (de) 1952-04-02 1955-01-31 Basf Ag Verfahren zur Herstellung von Kuepenfarbstoffen
US3948937A (en) * 1972-02-29 1976-04-06 E. I. Du Pont De Nemours And Company Pyrazole plant growth regulants
ZA744908B (en) * 1973-09-17 1975-08-27 American Cyanamid Co Catalytic dehydrogenation process for the preparation of 3,5-disubstituted pyrazoles
GB1484615A (en) * 1974-11-23 1977-09-01 Lepetit Spa Tricyclic n-containing derivatives
US4014896A (en) 1975-02-12 1977-03-29 American Cyanamid Company Catalytic dehydrogenation process for the preparation of 3,4,5-trisubstituted pyrazoles
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
US4877881A (en) 1987-04-06 1989-10-31 Warner-Lambert Company Process of preparing pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxygenase inhibitors
DE3903993A1 (de) 1989-02-10 1990-08-16 Basf Ag Diarylsubstituierte heterocyclische verbindungen, ihre herstellung und arzneimittel daraus
JPH04124178A (ja) * 1990-09-12 1992-04-24 Sds Biotech Kk 複素環式化合物および該化合物を含有する除草剤
ES2129539T3 (es) 1993-06-08 1999-06-16 Basf Ag Procedimiento para la obtencion de pirazoles n-substituidos.
US5783593A (en) * 1993-11-04 1998-07-21 Abbott Laboratories Inhibitors of squalene synthetase and protein farnesyltransferase
DE19500838A1 (de) * 1995-01-13 1996-07-18 Basf Ag Verfahren zur Herstellung von 3,5-Diarylpyrazolen
DE69935335T2 (de) 1998-08-07 2007-11-22 Novartis Vaccines and Diagnostics, Inc., Emeryville Pyrazole als modulatoren des östrogenrezeptors
AU1199600A (en) * 1998-10-02 2000-04-26 Board Of Trustees Of The University Of Illinois, The Estrogen receptor ligands
DE19904397A1 (de) 1999-02-04 2000-08-10 Bayer Ag Verwendung von Pyrazol-Carbonsäureamiden
JP2003523958A (ja) 1999-12-23 2003-08-12 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化されたシクロオキシゲナーゼ−２の阻害剤、組成物ならびに使用法
PT1282418E (pt) * 2000-05-19 2005-10-31 Applied Research Systems Utilizacao de derivados pirazolo para o tratamento da infertilidade
SI1373263T1 (en) 2001-04-05 2005-04-30 Torrent Pharmaceuticals Ltd Heterocyclic compounds for aging-related and diabetic vascular complications
US7041685B2 (en) 2001-06-08 2006-05-09 Cytovia, Inc. Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
IL161576A0 (en) 2001-10-26 2004-09-27 Aventis Pharma Inc Benzimidazoles and analogues and their use as protein kinases inhibitors
FR2831536A1 (fr) * 2001-10-26 2003-05-02 Aventis Pharma Sa Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
JP2005162612A (ja) * 2002-01-09 2005-06-23 Ajinomoto Co Inc アシルスルホンアミド誘導体
US6790979B2 (en) * 2002-04-17 2004-09-14 University Of North Carolina At Chapel Hill Curcumin analogues and uses thereof
NI200300045A (es) * 2002-04-26 2005-07-08 Pfizer Prod Inc Inhibidores de triariloxiariloxipirimidin-2,4,6-triona de metaloproteinasa.
WO2003105751A2 (en) * 2002-06-17 2003-12-24 Ho-Jeong Kwon Novel curcumin derivatives
EP1601657A1 (en) 2003-03-12 2005-12-07 Vertex Pharmaceuticals Incorporated Pyrazole modulators of atp-binding cassette transporters
WO2004099164A1 (en) 2003-05-02 2004-11-18 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection
GB0326601D0 (en) 2003-11-14 2003-12-17 Novartis Ag Organic compounds
WO2005094823A1 (ja) 2004-03-30 2005-10-13 Kyowa Hakko Kogyo Co., Ltd. Ｆｌｔ－３阻害剤
JP4859665B2 (ja) * 2004-03-30 2012-01-25 武田薬品工業株式会社 アルコキシフェニルプロパン酸誘導体

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